Axial Spondyloarthritis (AxSpA)NCT07914439
Inspiratory Muscle Training in Axial Spondyloarthritis
A study testing Aerobic Exercise, Conventional Spinal Mobility Exercises and Inspiratory Muscle Training in people with Axial Spondyloarthritis (AxSpA), run by Bursa Yuksek Ihtisas Training and Research Hospital at 1 site in Turkey (Türkiye).
Trial summary
This study investigated the effects of inspiratory muscle training (IMT) combined with aerobic exercise on diaphragm function, disease activity, functional exercise capacity, fatigue, sleep quality, and health-related quality of life in patients with axial spondyloarthritis (AxSpA). Read more about this study
- Who is it for?
- Ages 18 to 60 years, men only
- Conditions the study is for
- Axial Spondyloarthritis (AxSpA)
- What is being tested?
- Aerobic Exercise, Conventional Spinal Mobility Exercises and Inspiratory Muscle Training
- Type of treatment
- Lifestyle or therapy programme
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 42 participants
- Where
- 1 siteTurkey (Türkiye)
- Study dates
- 31 May 2023to 31 Mar 2024
- Phase
- Interventional
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 to 60 years
- Men only
- No healthy volunteers
- Adult
Who may be able to join
- Male patients aged 18-60 years.
- Diagnosis of axial spondyloarthritis according to the 2009 Assessment of SpondyloArthritis international Society (ASAS) classification criteria.
- Stable pharmacological treatment for at least 3 months prior to enrollment.
- Provision of written informed consent.
Who cannot join
- Acute infection.
- Disease exacerbation or flare within the previous 3 months.
- Changes in pharmacological treatment within the previous 3 months.
- Cardiopulmonary diseases.
- Endocrine diseases.
- Systemic diseases, including hepatic or renal failure.
Show all 10Show fewer
- Neuromuscular disorders.
- Malignancy.
- Spinal deformities.
- Orthopedic disabilities.
Trial locations and contacts
1 site in 1 country.
Turkey (Türkiye)1 site
University of Health Sciences Bursa Yüksek İhtisas Training and Research Hospital
Bursa, Bursa, 16800
About this study
Official title: Impact of Inspiratory Muscle Training Plus Aerobic Exercise on Diaphragm Function, Disease Activity, and Sleep Quality in Axial Spondyloarthritis: A Pilot Randomized Controlled Trial
This study investigated the effects of inspiratory muscle training (IMT) combined with aerobic exercise on diaphragm function, disease activity, functional exercise capacity, fatigue, sleep quality, and health-related quality of life in patients with axial spondyloarthritis (AxSpA).
Axial spondyloarthritis is a chronic inflammatory rheumatic disease that primarily affects the spine and sacroiliac joints. Reduced chest wall mobility and respiratory muscle function may contribute to decreased exercise capacity, fatigue, and impaired quality of life.
Read more
This randomized controlled trial was conducted at Bursa Yuksek Ihtisas Training and Research Hospital, Türkiye, between May 2023 and March 2024. Forty-two male patients aged 18-60 years were randomly allocated to two groups.
The control group received aerobic exercise and conventional spinal mobility exercises, while the intervention group received additional inspiratory muscle training using a respiratory resistance device. Both groups participated in a 12-week exercise program.
Participants were assessed at baseline and after 12 weeks using diaphragm ultrasonography, disease activity measures, functional exercise tests, and validated questionnaires assessing fatigue, sleep quality, and quality of life.
The study aimed to determine whether adding inspiratory muscle training to an aerobic exercise program provides additional clinical benefits for patients with axial spondyloarthritis.
Read the detailed description
Axial spondyloarthritis (AxSpA) is a chronic inflammatory rheumatic disease characterized by involvement of the axial skeleton, reduced spinal mobility, and functional limitations. Restricted chest wall expansion and respiratory muscle dysfunction may contribute to impaired ventilatory function, reduced exercise tolerance, fatigue, sleep disturbances, and decreased quality of life.
Although structured exercise is recommended as an important non-pharmacological intervention in AxSpA, the additional effects of inspiratory muscle training (IMT) combined with aerobic exercise on diaphragm morphology, disease activity, and patient-reported outcomes remain insufficiently investigated.
This randomized controlled trial was conducted at the Department of Physical Medicine and Rehabilitation, Bursa Yuksek Ihtisas Training and Research Hospital, Türkiye, between May 2023 and March 2024.
A total of 60 male patients with AxSpA were screened for eligibility. Forty-two eligible participants were randomly assigned to two parallel intervention groups using a lottery-based sealed-envelope randomization procedure. Thirty-five participants completed the 12-week intervention and follow-up assessments.
The first group received supervised treadmill-based aerobic exercise at 55-80% of maximum heart rate, three days per week, together with conventional spinal mobility exercises.
The second group received the same aerobic and conventional exercise program supplemented by inspiratory muscle training using a Powerbreathe respiratory resistance device. Inspiratory muscle training consisted of 30 breaths twice daily, five days per week, with progressive resistance adjustments during the intervention period.
Both groups continued their existing pharmacological treatments.
Clinical assessments were performed at baseline and after 12 weeks by an investigator blinded to group allocation.
Diaphragm morphology and function were evaluated using ultrasonographic measurements of end-inspiratory and end-expiratory diaphragm thickness and diaphragmatic thickening indices. Disease activity was assessed using the Ankylosing Spondylitis Disease Activity Score with C-reactive protein (ASDAS-CRP).
Functional exercise capacity was evaluated using the six-minute walk test. Additional assessments included the Bath Ankylosing Spondylitis Functional Index, chest expansion, Fatigue Severity Scale, Pittsburgh Sleep Quality Index, and Short Form-36 Health Survey.
The investigation was designed to evaluate the additional effects of inspiratory muscle training on respiratory, functional, and patient-reported outcomes when combined with a structured aerobic and conventional exercise program in male patients with axial spondyloarthritis.
- Conditions
- Axial Spondyloarthritis (AxSpA)
- Being tested
- Aerobic Exercise, Conventional Spinal Mobility Exercises, Inspiratory Muscle Training
- Keywords
- Inspiratory Muscle Training, Aerobic Exercise, Diaphragm Ultrasonography, Diaphragm Thickness, Disease Activity, Sleep Quality, Functional Exercise Capacity
- Medical subject headings
- Axial Spondyloarthritis, Sleep Initiation and Maintenance Disorders
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Aerobic ExerciseBehavioural
Supervised treadmill walking at 55-80% of maximum heart rate, three sessions per week for 12 weeks. Each session consisted of 40 minutes of aerobic exercise, preceded by 5-10 minutes of warm-up and followed by 5-10 minutes of cool-down.
Conventional Spinal Mobility ExercisesBehavioural
Home-based flexibility, range-of-motion, abdominal, and breathing exercises performed as 3 sets of 10 repetitions, five days per week, for 12 weeks.
Inspiratory Muscle TrainingBehavioural
Inspiratory muscle training was performed using a Powerbreathe Classic HR inspiratory resistance device. Participants performed 30 breaths twice daily, five days per week, for 12 weeks. Training started at a resistance of 10 cmH₂O and was progressively increased according to the study protocol. Resistance adjustments were reviewed weekly by a physiatrist.
| Study group | Role | What they receive |
|---|---|---|
| Aerobic and Conventional Exercise | Active comparator | Participants assigned to this group received supervised treadmill-based aerobic exercise at 55-80% of maximum heart rate, three days per week, for 12 weeks. Each session included 40 minutes of aerobic exercise, with additional warm-up and cool-down periods. Participants also performed conventional spinal mobility exercises five days per week and continued their existing pharmacological treatments. Receives: Behavioral: Aerobic Exercise; Behavioral: Conventional Spinal Mobility Exercises |
| Inspiratory Muscle Training Plus Aerobic and Conventional Exercise | Experimental | Participants assigned to this group received the same 12-week aerobic and conventional exercise program as the active comparator group, supplemented by inspiratory muscle training (IMT) using a Powerbreathe Classic HR device. IMT consisted of 30 breaths twice daily, five days per week, with progressive inspiratory resistance adjustments. Participants continued their existing pharmacological treatments throughout the study. Receives: Behavioral: Aerobic Exercise; Behavioral: Conventional Spinal Mobility Exercises; Behavioral: Inspiratory Muscle Training |
What is being measured
The primary outcome is the main question the study is designed to answer.
Change in Right Diaphragmatic End-Inspiratory Thickness
Right diaphragmatic end-inspiratory thickness was assessed using B-mode ultrasonography during deep inspiration. Three measurements were averaged. Thickness was recorded in centimeters, and change from baseline to Week 12 was evaluated.
Measured: Baseline (Week 0) and Week 12
Change in Left Diaphragmatic End-Inspiratory Thickness
Left diaphragmatic end-inspiratory thickness was measured using B-mode ultrasonography during deep inspiration. Three measurements were averaged, and the change in thickness, expressed in centimeters, was evaluated from baseline to Week 12.
Measured: Baseline (Week 0) and Week 12
Change in Ankylosing Spondylitis Disease Activity Score with C-Reactive Protein (ASDAS-CRP)
Disease activity was evaluated using ASDAS-CRP, a composite index incorporating patient-reported symptoms and serum C-reactive protein. Higher scores indicate greater disease activity. Change from baseline to Week 12 was assessed.
Measured: Baseline (Week 0) and Week 12
Change in Six-Minute Walk Test Distance (6MWT)
Functional exercise capacity was evaluated using the six-minute walk test. The total distance walked during six minutes was recorded in meters. Change in walking distance from baseline to Week 12 was assessed.
Measured: Baseline (Week 0) and Week 12
Secondary outcomes (7)
Change in Bath Ankylosing Spondylitis Functional Index (BASFI)
Functional limitations were evaluated using the 10-item Bath Ankylosing Spondylitis Functional Index. Total scores range from 0 to 10, with higher scores indicating greater functional impairment. Change from baseline to Week 12 was assessed.
Measured: Baseline (Week 0) and Week 12
Change in Fatigue Severity Scale (FSS) Score
Fatigue was evaluated using the nine-item Fatigue Severity Scale. The mean item score ranges from 1 to 7, with higher scores indicating greater fatigue severity. Change from baseline to Week 12 was assessed.
Measured: Baseline (Week 0) and Week 12
Change in Pittsburgh Sleep Quality Index (PSQI) Global Score
Sleep quality was assessed using the Pittsburgh Sleep Quality Index, with global scores ranging from 0 to 21. Higher scores indicate poorer sleep quality. Change from baseline to Week 12 was assessed.
Measured: Baseline (Week 0) and Week 12
Change in Chest Expansion
Chest expansion was assessed using a measuring tape at the nipple line while standing. The difference between maximal inspiration and maximal expiration was measured in centimeters at baseline and Week 12.
Measured: Baseline (Week 0) and Week 12
Change in Short Form-36 (SF-36) Health Survey Domain Scores
Health-related quality of life was assessed using the eight domains of the SF-36 Health Survey. Domain scores range from 0 to 100, with higher scores indicating better health-related quality of life. Changes from baseline to Week 12 were assessed.
Measured: Baseline (Week 0) and Week 12
Change in Right Diaphragmatic End-Expiratory Thickness
Right diaphragmatic thickness was measured during deep expiration using B-mode ultrasonography. Three measurements were averaged. Thickness was recorded in centimeters at baseline and Week 12.
Measured: Baseline (Week 0) and Week 12
Change in Left Diaphragmatic End-Expiratory Thickness
Left diaphragmatic thickness was measured during deep expiration using B-mode ultrasonography. Three measurements were averaged. Thickness was recorded in centimeters at baseline and Week 12.
Measured: Baseline (Week 0) and Week 12
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted3 Nov 2026
- Study start31 May 2023
- Primary completion31 Mar 2024
- Study completion31 Mar 2024
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Axial Spondyloarthritis (AxSpA)Studies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Model description
- This study used a two-arm, parallel-group randomized controlled design. Forty-two participants were allocated equally to an aerobic exercise and conventional exercise group (n=21) or an inspiratory muscle training plus aerobic and conventional exercise group (n=21). Both interventions lasted 12 weeks.
- Masking
- Single blind
- Who is masked
- Outcomes assessor
- Enrolment
- 42 participants (actual)
Sponsor and investigators
- Lead sponsor
- Bursa Yuksek Ihtisas Training and Research Hospital
- Sponsor type
- Other government
- Responsible party
- Principal investigator, Dr. Mertcan Ay, Bursa Yuksek Ihtisas Training and Research Hospital
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07914439
- Sponsor's protocol ID
- 2011/KAEK-25 2023/05-21
- Status last verified
- Oct 2026
- First submitted
- 28 Oct 2026
- Last updated
- 3 Nov 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- Yes: De-identified individual participant data underlying the results reported in the publication may be made available to qualified researchers upon reasonable request to the corresponding author, subject to institutional approval, applicable ethical requirements, and data protection regulations.
Study at a glance
From the registry record, last updated by the sponsor on 3 Nov 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Impact of Inspiratory Muscle Training Plus Aerobic Exercise on Diaphragm Function, Disease Activity, and Sleep Quality in Axial Spondyloarthritis: A Pilot Randomized Controlled Trial
- ClinicalTrials.gov ID
- NCT07914439
- Acronym / sponsor ID
- 2011/KAEK-25 2023/05-21
- Conditions
- Axial Spondyloarthritis (AxSpA)
- Keywords
- Inspiratory Muscle Training, Aerobic Exercise, Diaphragm Ultrasonography, Diaphragm Thickness, Disease Activity, Sleep Quality, Functional Exercise Capacity
- Study type
- Interventional
- Recruitment status
- Completed
- Enrolment
- 42 participants (actual)
- Lead sponsor
- Bursa Yuksek Ihtisas Training and Research HospitalOther government
- Study start
- 31 May 2023 (actual)
- Primary completion
- 31 Mar 2024 (actual)
- Study completion
- 31 Mar 2024 (actual)
- First posted
- 3 Nov 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
This study investigated the effects of inspiratory muscle training (IMT) combined with aerobic exercise on diaphragm function, disease activity, functional exercise capacity, fatigue, sleep quality, and health-related quality of life in patients with axial spondyloarthritis (AxSpA).
Axial spondyloarthritis is a chronic inflammatory rheumatic disease that primarily affects the spine and sacroiliac joints. Reduced chest wall mobility and respiratory muscle function may contribute to decreased exercise capacity, fatigue, and impaired quality of life.
This randomized controlled trial was conducted at Bursa Yuksek Ihtisas Training and Research Hospital, Türkiye, between May 2023 and March 2024. Forty-two male patients aged 18-60 years were randomly allocated to two groups.
The control group received aerobic exercise and conventional spinal mobility exercises, while the intervention group received additional inspiratory muscle training using a respiratory resistance device. Both groups participated in a 12-week exercise program.
Participants were assessed at baseline and after 12 weeks using diaphragm ultrasonography, disease activity measures, functional exercise tests, and validated questionnaires assessing fatigue, sleep quality, and quality of life.
The study aimed to determine whether adding inspiratory muscle training to an aerobic exercise program provides additional clinical benefits for patients with axial spondyloarthritis.
Detailed description
Axial spondyloarthritis (AxSpA) is a chronic inflammatory rheumatic disease characterized by involvement of the axial skeleton, reduced spinal mobility, and functional limitations. Restricted chest wall expansion and respiratory muscle dysfunction may contribute to impaired ventilatory function, reduced exercise tolerance, fatigue, sleep disturbances, and decreased quality of life.
Although structured exercise is recommended as an important non-pharmacological intervention in AxSpA, the additional effects of inspiratory muscle training (IMT) combined with aerobic exercise on diaphragm morphology, disease activity, and patient-reported outcomes remain insufficiently investigated.
This randomized controlled trial was conducted at the Department of Physical Medicine and Rehabilitation, Bursa Yuksek Ihtisas Training and Research Hospital, Türkiye, between May 2023 and March 2024.
A total of 60 male patients with AxSpA were screened for eligibility. Forty-two eligible participants were randomly assigned to two parallel intervention groups using a lottery-based sealed-envelope randomization procedure. Thirty-five participants completed the 12-week intervention and follow-up assessments.
The first group received supervised treadmill-based aerobic exercise at 55-80% of maximum heart rate, three days per week, together with conventional spinal mobility exercises.
The second group received the same aerobic and conventional exercise program supplemented by inspiratory muscle training using a Powerbreathe respiratory resistance device. Inspiratory muscle training consisted of 30 breaths twice daily, five days per week, with progressive resistance adjustments during the intervention period.
Both groups continued their existing pharmacological treatments.
Clinical assessments were performed at baseline and after 12 weeks by an investigator blinded to group allocation.
Diaphragm morphology and function were evaluated using ultrasonographic measurements of end-inspiratory and end-expiratory diaphragm thickness and diaphragmatic thickening indices. Disease activity was assessed using the Ankylosing Spondylitis Disease Activity Score with C-reactive protein (ASDAS-CRP).
Functional exercise capacity was evaluated using the six-minute walk test. Additional assessments included the Bath Ankylosing Spondylitis Functional Index, chest expansion, Fatigue Severity Scale, Pittsburgh Sleep Quality Index, and Short Form-36 Health Survey.
The investigation was designed to evaluate the additional effects of inspiratory muscle training on respiratory, functional, and patient-reported outcomes when combined with a structured aerobic and conventional exercise program in male patients with axial spondyloarthritis.
Study design
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Single blind (outcomes assessor)
- Number of arms
- 2
- Model description
- This study used a two-arm, parallel-group randomized controlled design. Forty-two participants were allocated equally to an aerobic exercise and conventional exercise group (n=21) or an inspiratory muscle training plus aerobic and conventional exercise group (n=21). Both interventions lasted 12 weeks.
| Arm | Type | Receives |
|---|---|---|
| Aerobic and Conventional Exercise | Active comparator | Behavioral: Aerobic Exercise, Behavioral: Conventional Spinal Mobility ExercisesParticipants assigned to this group received supervised treadmill-based aerobic exercise at 55-80% of maximum heart rate, three days per week, for 12 weeks. Each session included 40 minutes of aerobic exercise, with additional warm-up and cool-down periods. Participants also performed conventional spinal mobility exercises five days per week and continued their existing pharmacological treatments. |
| Inspiratory Muscle Training Plus Aerobic and Conventional Exercise | Experimental | Behavioral: Aerobic Exercise, Behavioral: Conventional Spinal Mobility Exercises, Behavioral: Inspiratory Muscle TrainingParticipants assigned to this group received the same 12-week aerobic and conventional exercise program as the active comparator group, supplemented by inspiratory muscle training (IMT) using a Powerbreathe Classic HR device. IMT consisted of 30 breaths twice daily, five days per week, with progressive inspiratory resistance adjustments. Participants continued their existing pharmacological treatments throughout the study. |
Who may qualify
- Ages
- 18 to 60 years
- Sex
- Male only
- Healthy volunteers
- Not accepted
- Age groups
- Adult
Key inclusion criteria (4 listed)
- Male patients aged 18-60 years.
- Diagnosis of axial spondyloarthritis according to the 2009 Assessment of SpondyloArthritis international Society (ASAS) classification criteria.
- Stable pharmacological treatment for at least 3 months prior to enrollment.
- Provision of written informed consent.
Key exclusion criteria (10 listed)
- Acute infection.
- Disease exacerbation or flare within the previous 3 months.
- Changes in pharmacological treatment within the previous 3 months.
- Cardiopulmonary diseases.
- Endocrine diseases.
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Aerobic ExerciseSupervised treadmill walking at 55-80% of maximum heart rate, three sessions per week for 12 weeks. Each session consisted of 40 minutes of aerobic exercise, preceded by 5-10 minutes of warm-up and followed by 5-10 minutes of cool-down. | Behavioural | Aerobic and Conventional Exercise, Inspiratory Muscle Training Plus Aerobic and Conventional Exercise |
| Conventional Spinal Mobility ExercisesHome-based flexibility, range-of-motion, abdominal, and breathing exercises performed as 3 sets of 10 repetitions, five days per week, for 12 weeks. | Behavioural | Aerobic and Conventional Exercise, Inspiratory Muscle Training Plus Aerobic and Conventional Exercise |
| Inspiratory Muscle TrainingInspiratory muscle training was performed using a Powerbreathe Classic HR inspiratory resistance device. Participants performed 30 breaths twice daily, five days per week, for 12 weeks. Training started at a resistance of 10 cmH₂O and was progressively increased according to the study protocol. Resistance adjustments were reviewed weekly by a physiatrist. | Behavioural | Inspiratory Muscle Training Plus Aerobic and Conventional Exercise |
Primary outcome
Change in Right Diaphragmatic End-Inspiratory Thickness
Time frame: Baseline (Week 0) and Week 12
Right diaphragmatic end-inspiratory thickness was assessed using B-mode ultrasonography during deep inspiration. Three measurements were averaged. Thickness was recorded in centimeters, and change from baseline to Week 12 was evaluated.
Change in Left Diaphragmatic End-Inspiratory Thickness
Time frame: Baseline (Week 0) and Week 12
Left diaphragmatic end-inspiratory thickness was measured using B-mode ultrasonography during deep inspiration. Three measurements were averaged, and the change in thickness, expressed in centimeters, was evaluated from baseline to Week 12.
Change in Ankylosing Spondylitis Disease Activity Score with C-Reactive Protein (ASDAS-CRP)
Time frame: Baseline (Week 0) and Week 12
Disease activity was evaluated using ASDAS-CRP, a composite index incorporating patient-reported symptoms and serum C-reactive protein. Higher scores indicate greater disease activity. Change from baseline to Week 12 was assessed.
Change in Six-Minute Walk Test Distance (6MWT)
Time frame: Baseline (Week 0) and Week 12
Functional exercise capacity was evaluated using the six-minute walk test. The total distance walked during six minutes was recorded in meters. Change in walking distance from baseline to Week 12 was assessed.
7 secondary outcomes
Change in Bath Ankylosing Spondylitis Functional Index (BASFI)
Time frame: Baseline (Week 0) and Week 12
Change in Fatigue Severity Scale (FSS) Score
Time frame: Baseline (Week 0) and Week 12
Change in Pittsburgh Sleep Quality Index (PSQI) Global Score
Time frame: Baseline (Week 0) and Week 12
Change in Chest Expansion
Time frame: Baseline (Week 0) and Week 12
Change in Short Form-36 (SF-36) Health Survey Domain Scores
Time frame: Baseline (Week 0) and Week 12
Change in Right Diaphragmatic End-Expiratory Thickness
Time frame: Baseline (Week 0) and Week 12
Change in Left Diaphragmatic End-Expiratory Thickness
Time frame: Baseline (Week 0) and Week 12
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 3 Nov 2026.
- Individual participant dataSharing planned: Yes. De-identified individual participant data underlying the results reported in the publication may be made available to qualified researchers upon reasonable request to the corresponding author, subject to institutional approval, applicable ethical requirements, and data protection regulations.
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
The record lists no contact. Use the official record to reach the sponsor.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Aerobic Exercise, Conventional Spinal Mobility Exercises and Inspiratory Muscle Training in people with Axial Spondyloarthritis (AxSpA), run by Bursa Yuksek Ihtisas Training and Research Hospital at 1 site in Turkey (Türkiye).
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 4 inclusion and 10 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 3 Nov 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Turkey (Türkiye). Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Change in Right Diaphragmatic End-Inspiratory Thickness (time frame: Baseline (Week 0) and Week 12). The study lists 4 primary outcomes in all. It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 3 Nov 2026.