Enhanced Recovery After Surgery (ERAS) ProtocolERASNCT07920458
Nursing-Led ERAS Protocol for Improving Recovery After Emergency Laparotomy
A study testing Nursing-Led Enhanced Recovery After Surgery (ERAS) Protocol and Routine Postoperative Care in people with Enhanced Recovery After Surgery (ERAS) Protocol, run by Al-Zaytoonah University of Jordan at 1 site in Egypt.
Trial summary
This study evaluates the effect of a nursing-led Enhanced Recovery After Surgery (ERAS) protocol on recovery among adults undergoing emergency laparotomy. A total of 120 eligible patients aged 18-65 years were randomly assigned to either a study group receiving the nursing-led ERAS protocol in addition to routine… Read more about this study
- Who is it for?
- Ages 18 to 65 yearsHealthy volunteers can take part
- Conditions the study is for
- Enhanced Recovery After Surgery (ERAS) Protocol
- What is being tested?
- Nursing-Led Enhanced Recovery After Surgery (ERAS) Protocol and Routine Postoperative Care
- Type of treatment
- Lifestyle or therapy programme
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 120 participants
- Where
- 1 siteEgypt
- Study dates
- 1 Nov 2025to 30 Apr 2026
- Phase
- Interventional
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 to 65 years
- All sexes
- Healthy volunteers accepted
- Adult, Older adult
Who may be able to join
- Adults aged 18-65 years undergoing emergency laparotomy for acute abdominal conditions, who are conscious and hemodynamically stable postoperatively.
Who cannot join
- Patients with impaired consciousness, intellectual disabilities, psychiatric disorders, prolonged postoperative mechanical ventilation, extended ICU stay, reoperation, or postoperative death before completion of the study.
Trial locations and contacts
1 site in 1 country.
About this study
Official title: Effect of a Nursing-Led Enhanced Recovery After Surgery Protocol on Postoperative Outcomes in Patients Undergoing Emergency Laparotomy
This study evaluates the effect of a nursing-led Enhanced Recovery After Surgery (ERAS) protocol on recovery among adults undergoing emergency laparotomy. A total of 120 eligible patients aged 18-65 years were randomly assigned to either a study group receiving the nursing-led ERAS protocol in addition to routine postoperative care or a control group receiving routine postoperative care alone. The protocol includes respiratory care, pain and nausea management, early mobilization, nutritional support, prevention of postoperative complications, catheter and drain management, psychosocial support, and patient education and discharge planning. Postoperative pain, recovery milestones, complications, hospital readmission, length of hospital stay, and satisfaction with nursing care are assessed.
Read the detailed description
Emergency laparotomy is a major surgical procedure performed for acute abdominal conditions and is associated with postoperative pain, delayed mobilization and gastrointestinal recovery, postoperative complications, prolonged hospitalization, and readmission. Enhanced Recovery After Surgery (ERAS) is an evidence-based approach that integrates multiple perioperative strategies to support recovery. This study evaluates a nursing-led ERAS protocol among patients undergoing emergency laparotomy.
The study used a randomized controlled trial design with two parallel groups. Eligible participants were randomly allocated in a 1:1 ratio using a computer-generated randomization sequence. The study was conducted in the General Surgical Unit at Menoufia University Hospital, Egypt. The protocol was developed based on ERAS Society recommendations for emergency laparotomy and contemporary evidence regarding enhanced recovery interventions in abdominal surgery.
Before implementation, assigned staff nurses received orientation regarding the objectives, components, and procedures of the nursing-led ERAS protocol to promote standardized delivery and intervention fidelity. The protocol was individualized according to each patient's clinical condition, hemodynamic stability, tolerance to activity and oral intake, and physician orders. Adherence was monitored daily using an ERAS implementation checklist, direct observation, and review of patient records.
Postoperative pain was assessed during the first three postoperative days using the Numeric Pain Rating Scale. Recovery outcomes included postoperative mobilization, nutritional and gastrointestinal recovery, postoperative complications, length of hospital stay, and hospital readmission within 30 days after discharge. Patient satisfaction with nursing care was assessed before discharge using the Patient Satisfaction with Nursing Care Quality Questionnaire.
Outcome assessment was performed by a trained nurse who was not involved in delivering the intervention and was blinded to participants' group allocation. The same standardized assessment procedures and instruments were used for participants in both groups to minimize measurement bias. Written informed consent was obtained before enrollment, and the study received ethical approval from the Ethical and Research Committee of the Faculty of Nursing, Menoufia University (Approval No. 133).
- Being tested
- Nursing-Led Enhanced Recovery After Surgery (ERAS) Protocol, Routine Postoperative Care
- Keywords
- Emergency Laparotomy, Enhanced Recovery After Surgery, ERAS, Nursing-Led Intervention, Postoperative Recovery, Patient Satisfaction
- Medical subject headings
- Patient Satisfaction
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Nursing-Led Enhanced Recovery After Surgery (ERAS) ProtocolBehavioural
A structured nursing-led ERAS protocol consisting of eight domains: respiratory care, pain and PONV management, early mobilization and VTE prevention, nutritional and gastrointestinal recovery, complication prevention, catheter and drain management, delirium prevention and psychosocial support, and patient education, discharge planning, and follow-up. The protocol was provided in addition to routine postoperative care throughout hospitalization.
Routine Postoperative CareOther
Routine postoperative nursing care provided according to the hospital's standard policy.
| Study group | Role | What they receive |
|---|---|---|
| Nursing-Led Enhanced Recovery After Surgery (ERAS) Protocol | Experimental | Participants received a nursing-led Enhanced Recovery After Surgery (ERAS) protocol in addition to routine postoperative care following emergency laparotomy. The protocol included eight domains: respiratory care and prevention of pulmonary complications; pain and postoperative nausea and vomiting management; early mobilization and venous thromboembolism prevention; nutritional support and gastrointestinal recovery; monitoring and prevention of postoperative complications; catheter and drain management; delirium prevention and psychosocial support; and patient education, discharge planning, and follow-up. The protocol was individualized according to each patient's clinical condition, hemodynamic stability, and tolerance, and was implemented throughout hospitalization until discharge. Compliance was monitored daily. Receives: Behavioral: Nursing-Led Enhanced Recovery After Surgery (ERAS) Protocol |
| Routine Postoperative Care | Active comparator | Participants received routine postoperative nursing care according to the hospital's standard policy without the Nursing-Led ERAS protocol. Routine medical and nursing management continued throughout hospitalization. Receives: Other: Routine Postoperative Care |
What is being measured
The primary outcome is the main question the study is designed to answer.
Postoperative Pain Intensity
Postoperative pain intensity was assessed using the Numeric Pain Rating Scale (NPRS), an 11-point scale ranging from 0 (no pain) to 10 (worst possible pain). Mean pain scores were compared between the study and control groups.
Measured: Postoperative Days 1, 2, and 3.
Time to First Passage of Flatus
The time interval, measured in hours, from the end of emergency laparotomy surgery to the first documented passage of intestinal flatus. The time will be recorded from nursing documentation and compared between the study and control groups.
Measured: From the end of surgery until the first documented passage of flatus or hospital discharge, whichever occurs first, during the postoperative hospitalization.
Time to First Bowel Movement
The time interval, measured in hours, from the end of emergency laparotomy surgery to the first documented bowel movement. The time will be recorded from nursing documentation and compared between the study and control groups.
Measured: From the end of surgery until the first documented bowel movement or hospital discharge, whichever occurs first, during the postoperative hospitalization.
Length of Hospital Stay
Total duration of hospitalization, measured in days from hospital admission until hospital discharge. The duration will be calculated from admission and discharge dates documented in the patient's medical record and compared between the study and control groups.
Measured: From the date of hospital admission until the date of hospital discharge during the index hospitalization.
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted5 Nov 2026
- Study start1 Nov 2025
- Primary completion30 Apr 2026
- Study completion30 Apr 2026
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Enhanced Recovery After Surgery (ERAS) ProtocolStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Supportive care
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Single blind
- Who is masked
- Outcomes assessor
- Enrolment
- 120 participants (actual)
Sponsor and investigators
- Lead sponsor
- Al-Zaytoonah University of Jordan
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Faten Mabrouk Nouh, Menoufia University
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07920458
- Sponsor's protocol ID
- 133
- Acronym
- ERAS
- Status last verified
- Oct 2026
- First submitted
- 23 Sep 2026
- Last updated
- 5 Nov 2026
- Results posted
- No
- Data monitoring committee
- Yes
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- Yes: De-identified individual participant data (IPD) underlying the results reported in this study will be shared upon reasonable request. The data will include sociodemographic and clinical characteristics, postoperative pain scores, postoperative recovery milestones, complications, hospital readmission, length of hospital stay, and patient satisfaction with nursing care. All shared data will be de-identified to ensure participants' confidentiality and privacy.
Study at a glance
From the registry record, last updated by the sponsor on 5 Nov 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Effect of a Nursing-Led Enhanced Recovery After Surgery Protocol on Postoperative Outcomes in Patients Undergoing Emergency Laparotomy
- ClinicalTrials.gov ID
- NCT07920458
- Acronym / sponsor ID
- ERAS / 133
- Keywords
- Emergency Laparotomy, Enhanced Recovery After Surgery, ERAS, Nursing-Led Intervention, Postoperative Recovery, Patient Satisfaction
- Study type
- Interventional
- Recruitment status
- Completed
- Enrolment
- 120 participants (actual)
- Lead sponsor
- Al-Zaytoonah University of JordanUniversity, hospital or other
- Study start
- 1 Nov 2025 (actual)
- Primary completion
- 30 Apr 2026 (actual)
- Study completion
- 30 Apr 2026 (actual)
- First posted
- 5 Nov 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
This study evaluates the effect of a nursing-led Enhanced Recovery After Surgery (ERAS) protocol on recovery among adults undergoing emergency laparotomy. A total of 120 eligible patients aged 18-65 years were randomly assigned to either a study group receiving the nursing-led ERAS protocol in addition to routine postoperative care or a control group receiving routine postoperative care alone. The protocol includes respiratory care, pain and nausea management, early mobilization, nutritional support, prevention of postoperative complications, catheter and drain management, psychosocial support, and patient education and discharge planning. Postoperative pain, recovery milestones, complications, hospital readmission, length of hospital stay, and satisfaction with nursing care are assessed.
Detailed description
Emergency laparotomy is a major surgical procedure performed for acute abdominal conditions and is associated with postoperative pain, delayed mobilization and gastrointestinal recovery, postoperative complications, prolonged hospitalization, and readmission. Enhanced Recovery After Surgery (ERAS) is an evidence-based approach that integrates multiple perioperative strategies to support recovery. This study evaluates a nursing-led ERAS protocol among patients undergoing emergency laparotomy.
The study used a randomized controlled trial design with two parallel groups. Eligible participants were randomly allocated in a 1:1 ratio using a computer-generated randomization sequence. The study was conducted in the General Surgical Unit at Menoufia University Hospital, Egypt. The protocol was developed based on ERAS Society recommendations for emergency laparotomy and contemporary evidence regarding enhanced recovery interventions in abdominal surgery.
Before implementation, assigned staff nurses received orientation regarding the objectives, components, and procedures of the nursing-led ERAS protocol to promote standardized delivery and intervention fidelity. The protocol was individualized according to each patient's clinical condition, hemodynamic stability, tolerance to activity and oral intake, and physician orders. Adherence was monitored daily using an ERAS implementation checklist, direct observation, and review of patient records.
Postoperative pain was assessed during the first three postoperative days using the Numeric Pain Rating Scale. Recovery outcomes included postoperative mobilization, nutritional and gastrointestinal recovery, postoperative complications, length of hospital stay, and hospital readmission within 30 days after discharge. Patient satisfaction with nursing care was assessed before discharge using the Patient Satisfaction with Nursing Care Quality Questionnaire.
Outcome assessment was performed by a trained nurse who was not involved in delivering the intervention and was blinded to participants' group allocation. The same standardized assessment procedures and instruments were used for participants in both groups to minimize measurement bias. Written informed consent was obtained before enrollment, and the study received ethical approval from the Ethical and Research Committee of the Faculty of Nursing, Menoufia University (Approval No. 133).
Study design
- Primary purpose
- Supportive care
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Single blind (outcomes assessor)
- Number of arms
- 2
| Arm | Type | Receives |
|---|---|---|
| Nursing-Led Enhanced Recovery After Surgery (ERAS) Protocol | Experimental | Behavioral: Nursing-Led Enhanced Recovery After Surgery (ERAS) ProtocolParticipants received a nursing-led Enhanced Recovery After Surgery (ERAS) protocol in addition to routine postoperative care following emergency laparotomy. The protocol included eight domains: respiratory care and prevention of pulmonary complications; pain and postoperative nausea and vomiting management; early mobilization and venous thromboembolism prevention; nutritional support and gastrointestinal recovery; monitoring and prevention of postoperative complications; catheter and drain management; delirium prevention and psychosocial support; and patient education, discharge planning, and follow-up. The protocol was individualized according to each patient's clinical condition, hemodynamic stability, and tolerance, and was implemented throughout hospitalization until discharge. Compliance was monitored daily. |
| Routine Postoperative Care | Active comparator | Other: Routine Postoperative CareParticipants received routine postoperative nursing care according to the hospital's standard policy without the Nursing-Led ERAS protocol. Routine medical and nursing management continued throughout hospitalization. |
Who may qualify
- Ages
- 18 to 65 years
- Sex
- All
- Healthy volunteers
- Accepted
- Age groups
- Adult, Older adult
Key inclusion criteria (1 listed)
- Adults aged 18-65 years undergoing emergency laparotomy for acute abdominal conditions, who are conscious and hemodynamically stable postoperatively.
Key exclusion criteria (1 listed)
- Patients with impaired consciousness, intellectual disabilities, psychiatric disorders, prolonged postoperative mechanical ventilation, extended ICU stay, reoperation, or postoperative death before completion of the study.
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Nursing-Led Enhanced Recovery After Surgery (ERAS) ProtocolA structured nursing-led ERAS protocol consisting of eight domains: respiratory care, pain and PONV management, early mobilization and VTE prevention, nutritional and gastrointestinal recovery, complication prevention, catheter and drain management, delirium prevention and psychosocial support, and patient education, discharge planning, and follow-up. The protocol was provided in addition to routine postoperative care throughout hospitalization. | Behavioural | Nursing-Led Enhanced Recovery After Surgery (ERAS) Protocol |
| Routine Postoperative CareRoutine postoperative nursing care provided according to the hospital's standard policy. | Other | Routine Postoperative Care |
Primary outcome
Postoperative Pain Intensity
Time frame: Postoperative Days 1, 2, and 3.
Postoperative pain intensity was assessed using the Numeric Pain Rating Scale (NPRS), an 11-point scale ranging from 0 (no pain) to 10 (worst possible pain). Mean pain scores were compared between the study and control groups.
Time to First Passage of Flatus
Time frame: From the end of surgery until the first documented passage of flatus or hospital discharge, whichever occurs first, during the postoperative hospitalization.
The time interval, measured in hours, from the end of emergency laparotomy surgery to the first documented passage of intestinal flatus. The time will be recorded from nursing documentation and compared between the study and control groups.
Time to First Bowel Movement
Time frame: From the end of surgery until the first documented bowel movement or hospital discharge, whichever occurs first, during the postoperative hospitalization.
The time interval, measured in hours, from the end of emergency laparotomy surgery to the first documented bowel movement. The time will be recorded from nursing documentation and compared between the study and control groups.
Length of Hospital Stay
Time frame: From the date of hospital admission until the date of hospital discharge during the index hospitalization.
Total duration of hospitalization, measured in days from hospital admission until hospital discharge. The duration will be calculated from admission and discharge dates documented in the patient's medical record and compared between the study and control groups.
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 5 Nov 2026.
- ERAS Society consensus guidelines for perioperative care in emergency laparotomy, which informed the development of the Nursing-Led ERAS Protocol used in this study.Link provided by the sponsor.
- Individual participant dataSharing planned: Yes. De-identified individual participant data (IPD) underlying the results reported in this study will be shared upon reasonable request. The data will include sociodemographic and clinical characteristics, postoperative pain scores, postoperative recovery milestones, complications, hospital readmission, length of hospital stay, and patient satisfaction with nursing care. All shared data will be de-identified to ensure participants' confidentiality and privacy.
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
The record lists no contact. Use the official record to reach the sponsor.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Nursing-Led Enhanced Recovery After Surgery (ERAS) Protocol and Routine Postoperative Care in people with Enhanced Recovery After Surgery (ERAS) Protocol, run by Al-Zaytoonah University of Jordan at 1 site in Egypt.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 1 inclusion and 1 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 5 Nov 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Egypt. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Postoperative Pain Intensity (time frame: Postoperative Days 1, 2, and 3.). The study lists 4 primary outcomes in all. It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 5 Nov 2026.