Hypotonic Cerebral PalsyNCT07921186
Comparison of Vestibular Stimulation and Core Stability Training on Sitting Balance in Hypotonic CP
A study testing Core stability training with conventional therapy and Vestibular Stimulation with conventional therapy in people with Hypotonic Cerebral Palsy, run by Riphah International University at 1 site in Pakistan.
Trial summary
To compare the effectiveness of core stability training and vestibular stimulation on sitting balance in hypotonic Cerebral Palsy Read more about this study
- Who is it for?
- Ages 2 to 8 years
- Conditions the study is for
- Hypotonic Cerebral Palsy
- What is being tested?
- Core stability training with conventional therapy and Vestibular Stimulation with conventional therapy
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 32 participants
- Where
- 1 sitePakistan
- Study dates
- 1 Jul 2026to Mar 2027
- Phase
- Interventional
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 2 to 8 years
- All sexes
- No healthy volunteers
- Child
Who may be able to join
- Age between 2-8 years.
- Clinical diagnosis of hypotonic cerebral palsy.
- Segmental assessment of trunk control - not full independent trunk control.
- Cognitive ability (who follows command)
- Medical stability
Who cannot join
- Progressive neurological disorder.
- Uncontrolled epilepsy.
- Visual or hearing impairment
- Behavioral problems
- Vertigo
Trial locations and contacts
1 site in 1 country. Contact the study team or a site near you to ask about taking part.
Pakistan1 site, 1 recruiting
- Recruiting
Helping Hand for Relief and Development
Chakwal, Punjab Province
Qamar Mehmood, 03335151063, qamar.mehmood@riphah.edu.pk
Zahra Jahan, MS-PPT
About this study
Official title: Comparison of Vestibular Stimulation and Core Stability Training on Sitting Balance in Hypotonic Cerebral Palsy
To compare the effectiveness of core stability training and vestibular stimulation on sitting balance in hypotonic Cerebral Palsy
- Conditions
- Hypotonic Cerebral Palsy
- Being tested
- Core stability training with conventional therapy, Vestibular Stimulation with conventional therapy
- Medical subject headings
- Cerebral Palsy
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Core stability training with conventional therapyOther
Basic core stability training with supine bridging, lateral weight shifting and conventional therapy with trunk facilitation. Sessions will be conducted 5 time per week for 8 weeks. Sessions lasts for 30 minutes.
Vestibular Stimulation with conventional therapyOther
Vestibular stimulation with gym ball and swing along with conventional therapy. Sessions will be conducted 5 time per week for 8 weeks. Sessions lasts for 30 minutes.
| Study group | Role | What they receive |
|---|---|---|
| Core stability and conventional | Experimental | Core stability training and conventional therapy on sitting balance in Hypotonic cerebral palsy Receives: Other: Core stability training with conventional therapy |
| Vestibular stimulation and conventional therapy | Active comparator | Vestibular stimulation and conventional therapy on sitting balance in hypotonic cerebral palsy Receives: Other: Vestibular Stimulation with conventional therapy |
What is being measured
The primary outcome is the main question the study is designed to answer.
Segmental assessment of trunk control
To evaluate trunk stability and it has 7 levels. Each level consists of 3 components(static, active and reactive). Trunk stability will be measured baseline (0 week), mid intervention(4 weeks) and post intervention(8 weeks).
Measured: week 0 , week 4, week 8
Secondary outcomes (3)
Pediatric Balance Scale
To assess static and dynamic balance. It consists of 14 items scoring from (0=unable, 1=maximal assistance , 2= moderate assistance , 3=minimal assistance). Total score is 56.Static and dynamic balance will be measured baseline (0 week), mid intervention(4 weeks) and post intervention(8 weeks).
Measured: week 0 , week 4, week 8
Pediatric Evaluation of Disability inventory
To assess functional mobility and daily activities. it consists of 3 domains scoring from (0= child does not perform activity , 1 = child perform activity). Total functional score is 12. Functional mobility will be measured baseline (0 week), mid intervention(4 weeks) and post intervention(8 weeks).
Measured: week 0 , week 4, week 8
Reaching Performance Scale
To assess quality of reaching movements. It has 6 components scoring from(0=no performance , 1= poor performance, 2= moderate performance, 3= good performance) Total score is 18.Quality of reaching movement will be measured baseline (0 week), mid intervention(4 weeks) and post intervention(8 weeks).
Measured: week 0 , week 4, week 8
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted6 Nov 2026
- Study start1 Jul 2026
- Primary completionMar 2027 (estimated)
- Study completionMar 2027 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Publications (10)Papers the sponsor has linked to this study.
- Other trials for Hypotonic Cerebral PalsyStudies of the same condition, open and under way.
- More trials run by Riphah International UniversityThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Double blind
- Who is masked
- Participant, Outcomes assessor
- Enrolment
- 32 participants (estimated)
Sponsor and investigators
- Lead sponsor
- Riphah International University
- Sponsor type
- University, hospital or other
- Responsible party
- Sponsor
- Investigators
- Qamar Mehmood, MS, Principal investigator, Riphah International University
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07921186
- Sponsor's protocol ID
- REC/MS-PT/02473 Zahra Jahan
- Status last verified
- Nov 2026
- First submitted
- 2 Nov 2026
- Last updated
- 6 Nov 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No
Publications
Khan MZ, Khaliq S, Asim M, Mahmood NQK, Khan FA, Khan FA, et al. Impact of Vestibular Stimulation on Motor Function and Balance in Children with Hypotonic Cerebral Palsy: A Randomized Controlled Trial. Multidisciplinary Surgical Research Annals. 2025;3(2):1-7.
Sivaramachandran R, Natarajan M. Impact of sensory perceptual motor core stability training on sitting control in children with cerebral palsy. Fisioterapia em Movimento. 2025;38:e38118.
Parashar A, Pattnaik M, Mohanty P. Effect of vestibular stimulation versus whole body vibration on standing balance in children with spastic diplegic cerebral palsy. J Nov Physiother. 2017;7(348):2.
Rani M, Waqas S, Asim HM, Tariq M, Javaid A. Effectiveness of Vestibular Stimulation on Balance Using Swing Therapy in Children with Hypotonic Cerebral Palsy. Annals of King Edward Medical University. 2022;28(1).
Yılmaz DA, Yildiz M, Yildirim MS, Ozlenir M. The The effects of core stability exercises on proprioception and balance in children with hemiplegic cerebral palsy. Retos. 2023;50:1123-8
Elshafey MA, Abdrabo MS, Elnaggar RK. Effects of a core stability exercise program on balance and coordination in children with cerebellar ataxic cerebral palsy. J Musculoskelet Neuronal Interact. 2022 Jun 1;22(2):172-178.
PubMed 35642697Elbasan B, Akaya KU, Akyuz M, Oskay D. Effects of neuromuscular electrical stimulation and Kinesio Taping applications in children with cerebral palsy on postural control and sitting balance. J Back Musculoskelet Rehabil. 2018 Feb 6;31(1):49-55. doi: 10.3233/BMR-169656.
PubMed 28869434Mohamed N, Ibrahim MB, El-Agamy OA, Aldhahi MI, Elsebahy SY. Effects of Core Stability Training on Balance, Standing, and Gait in Children with Mild Cerebral Palsy: A Randomized Controlled Trial. Healthcare (Basel). 2025 May 29;13(11):1296. doi: 10.3390/healthcare13111296.
PubMed 40508909Vitrikas K, Dalton H, Breish D. Cerebral Palsy: An Overview. Am Fam Physician. 2020 Feb 15;101(4):213-220.
PubMed 32053326Aravamuthan BR, Fehlings D, Shetty S, Fahey M, Gilbert L, Tilton A, Kruer MC. Variability in Cerebral Palsy Diagnosis. Pediatrics. 2021 Feb;147(2):e2020010066. doi: 10.1542/peds.2020-010066. Epub 2021 Jan 5.
PubMed 33402528
Study at a glance
From the registry record, last updated by the sponsor on 6 Nov 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Comparison of Vestibular Stimulation and Core Stability Training on Sitting Balance in Hypotonic Cerebral Palsy
- ClinicalTrials.gov ID
- NCT07921186
- Acronym / sponsor ID
- REC/MS-PT/02473 Zahra Jahan
- Conditions
- Hypotonic Cerebral Palsy
- Study type
- Interventional
- Recruitment status
- Recruiting
- Enrolment
- 32 participants (estimated)
- Lead sponsor
- Riphah International UniversityUniversity, hospital or other
- Study start
- 1 Jul 2026 (actual)
- Primary completion
- Mar 2027 (estimated)
- Study completion
- Mar 2027 (estimated)
- First posted
- 6 Nov 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
To compare the effectiveness of core stability training and vestibular stimulation on sitting balance in hypotonic Cerebral Palsy
Study design
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Double blind (participant, outcomes assessor)
- Number of arms
- 2
| Arm | Type | Receives |
|---|---|---|
| Core stability and conventional | Experimental | Other: Core stability training with conventional therapyCore stability training and conventional therapy on sitting balance in Hypotonic cerebral palsy |
| Vestibular stimulation and conventional therapy | Active comparator | Other: Vestibular Stimulation with conventional therapyVestibular stimulation and conventional therapy on sitting balance in hypotonic cerebral palsy |
Who may qualify
- Ages
- 2 to 8 years
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Child
Key inclusion criteria (5 listed)
- Age between 2-8 years.
Key exclusion criteria (5 listed)
- Progressive neurological disorder.
- Uncontrolled epilepsy.
- Visual or hearing impairment
- Behavioral problems
- Vertigo
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Core stability training with conventional therapyBasic core stability training with supine bridging, lateral weight shifting and conventional therapy with trunk facilitation. Sessions will be conducted 5 time per week for 8 weeks. Sessions lasts for 30 minutes. | Other | Core stability and conventional |
| Vestibular Stimulation with conventional therapyVestibular stimulation with gym ball and swing along with conventional therapy. Sessions will be conducted 5 time per week for 8 weeks. Sessions lasts for 30 minutes. | Other | Vestibular stimulation and conventional therapy |
Primary outcome
Segmental assessment of trunk control
Time frame: week 0 , week 4, week 8
To evaluate trunk stability and it has 7 levels. Each level consists of 3 components(static, active and reactive). Trunk stability will be measured baseline (0 week), mid intervention(4 weeks) and post intervention(8 weeks).
3 secondary outcomes
Pediatric Balance Scale
Time frame: week 0 , week 4, week 8
Pediatric Evaluation of Disability inventory
Time frame: week 0 , week 4, week 8
Reaching Performance Scale
Time frame: week 0 , week 4, week 8
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 6 Nov 2026.
- BackgroundKhan MZ, Khaliq S, Asim M, Mahmood NQK, Khan FA, Khan FA, et al. Impact of Vestibular Stimulation on Motor Function and Balance in Children with Hypotonic Cerebral Palsy: A Randomized Controlled Trial. Multidisciplinary Surgical Research Annals. 2025;3(2):1-7.
- BackgroundSivaramachandran R, Natarajan M. Impact of sensory perceptual motor core stability training on sitting control in children with cerebral palsy. Fisioterapia em Movimento. 2025;38:e38118.
- BackgroundParashar A, Pattnaik M, Mohanty P. Effect of vestibular stimulation versus whole body vibration on standing balance in children with spastic diplegic cerebral palsy. J Nov Physiother. 2017;7(348):2.
- BackgroundRani M, Waqas S, Asim HM, Tariq M, Javaid A. Effectiveness of Vestibular Stimulation on Balance Using Swing Therapy in Children with Hypotonic Cerebral Palsy. Annals of King Edward Medical University. 2022;28(1).
- BackgroundYılmaz DA, Yildiz M, Yildirim MS, Ozlenir M. The The effects of core stability exercises on proprioception and balance in children with hemiplegic cerebral palsy. Retos. 2023;50:1123-8
- Background: PubMed 35642697Elshafey MA, Abdrabo MS, Elnaggar RK. Effects of a core stability exercise program on balance and coordination in children with cerebellar ataxic cerebral palsy. J Musculoskelet Neuronal Interact. 2022 Jun 1;22(2):172-178.
- Background: PubMed 28869434Elbasan B, Akaya KU, Akyuz M, Oskay D. Effects of neuromuscular electrical stimulation and Kinesio Taping applications in children with cerebral palsy on postural control and sitting balance. J Back Musculoskelet Rehabil. 2018 Feb 6;31(1):49-55. doi: 10.3233/BMR-169656.
- Background: PubMed 40508909Mohamed N, Ibrahim MB, El-Agamy OA, Aldhahi MI, Elsebahy SY. Effects of Core Stability Training on Balance, Standing, and Gait in Children with Mild Cerebral Palsy: A Randomized Controlled Trial. Healthcare (Basel). 2025 May 29;13(11):1296. doi: 10.3390/healthcare13111296.
- Background: PubMed 32053326Vitrikas K, Dalton H, Breish D. Cerebral Palsy: An Overview. Am Fam Physician. 2020 Feb 15;101(4):213-220.
- Background: PubMed 33402528Aravamuthan BR, Fehlings D, Shetty S, Fahey M, Gilbert L, Tilton A, Kruer MC. Variability in Cerebral Palsy Diagnosis. Pediatrics. 2021 Feb;147(2):e2020010066. doi: 10.1542/peds.2020-010066. Epub 2021 Jan 5.
- Individual participant dataSharing planned: No
Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
Qamar Mehmood, MS principal investigator
Riphah International University
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Core stability training with conventional therapy and Vestibular Stimulation with conventional therapy in people with Hypotonic Cerebral Palsy, run by Riphah International University at 1 site in Pakistan.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 5 inclusion and 5 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: looking for participants now, as of the sponsor's last update on 6 Nov 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Pakistan. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
Contact Qamar Mehmood (03335151063, qamar.mehmood@riphah.edu.pk), or a site near the patient. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Segmental assessment of trunk control (time frame: week 0 , week 4, week 8). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
On the ClinicalTrials.gov record for NCT07921186, which also lists 10 linked publications.
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 6 Nov 2026.