Clinical trials: A
Autism
the Efficacy of Oral Motor Therapy in Children With Autism
Children with Autism spectrum disorders have speech disorders, which in turn aggravate communication difficulties and lead to an increase in their core symptoms.
- Trial name
- NCT05406076
- Testing
- oral motor therapy, ABA
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- The First Affiliated Hospital of Anhui Medical University
SCHIZOPHRENIA 1 (Disorder), Simulation Based Learning
Simulation-Based Schizophrenia Training in Nursing Education
This study aims to examine the effect of a schizophrenia scenario-based simulation on nursing students' knowledge, empathy, and caregiving competence. The study uses a single-group pre-test/post-test (quasi-experimental) design.
- Conditions
- SCHIZOPHRENIA 1 (Disorder), Simulation Based Learning, Nursing Students
- Trial name
- NCT07757750
- Testing
- Simulation
- Where
- Turkey (Türkiye)
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- Medipol University
Syncope
The Diagnostic Performance of Tilt Test in Athletes
In the present study the investigators evaluate the sensitivity and specificity of passive tilt test in athletes, as well as their haemodynamic responses and autonomic nervous system activity during head-up tilt.
- Trial name
- NCT02316860
- Testing
- Passive tilt test
- Where
- Greece
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Aristotle University Of Thessaloniki
Substance Abuse
Youth Substance Use Prevention/Reduction Through Science-based Drug Abuse Education
Our primary goal is to conduct a pilot study of the effects of a new potential strategy for youth substance abuse prevention - science-based drug education integrated into the high school science curriculum.
- Trial name
- NCT00612482
- Testing
- drug prevention curriculum
- Where
- United States
- Volunteers
- 225 people, healthy volunteers welcome
- Sponsor
- Boston Children's Hospital
Chikungunya Virus
A Phase 3 Trial of the VLP-Based Chikungunya Vaccine PXVX0317 (CHIKV VLP Vaccine)
The goal of this multi-center, randomized, double blind, placebo controlled study is to evaluate the safety and immunogenicity of PXVX0317 (CHIKV VLP vaccine) in healthy adult and adolescent subjects.
- Trial name
- NCT05072080
- Testing
- CHIKV VLP/adjuvant
- Where
- 47 sites in United States
- Volunteers
- 3,258 people, healthy volunteers welcome
- Sponsor
- Bavarian Nordic
Contraception
Study to Evaluate the Contraceptive Efficacy/Safety of a Low Dose EE/LNG Transdermal Contraceptive Delivery System
The purpose of the study is to evaluate the efficacy and safety of a low dose transdermal contraceptive delivery system containing ethinyl estradiol and levonorgestrel.
- Trial name
- NCT01181479
- Testing
- AG200-15 (cycles 1-13), Lessina crossover to AG200-15
- Where
- 80 sites in United States
- Volunteers
- 1,504 people, healthy volunteers welcome
- Sponsor
- Agile Therapeutics
Cleft Palate Lip
Cleft Palate Surgical Simulator: Improvement in Surgical Trainees' Knowledge and Confidence.
Trainees' experience in cleft surgery is limited due to the high-risk nature of the surgery and centralization of cleft care. Simulations allow trainees to learn complex surgical skills whilst ensuring patient safety.
- Trial name
- NCT04489680
- Testing
- Educational
- Where
- United Kingdom
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Guy's and St Thomas' NHS Foundation Trust
Anaplastic Ependymoma, Atypical Teratoid/Rhabdoid Tumor
Chemotherapy and Donor Stem Transplant for the Treatment of Patients With High Grade Brain Cancer
This phase I trial investigates the side effects and effectiveness of chemotherapy followed by a donor (allogeneic) stem cell transplant when given to patients with high grade brain cancer.
- Conditions
- Anaplastic Ependymoma, Atypical Teratoid/Rhabdoid Tumor, Central Nervous System Germ Cell Tumor, Choroid Plexus Carcinoma
- Trial name
- NCT04521946
- Testing
- Etoposide, Fludarabine Phosphate, Hematopoietic Cell Transplantation
- Volunteers
- healthy volunteers welcome
- Sponsor
- M.D. Anderson Cancer Center
Iron Deficiency Anemia
Prevalence of Oral Manifestations of Iron Deficiency Anemia in a Sample of Egyptian Population
According to WHO Reportin 2002, iron deficiency anemia was considered to be the most important contributing factor to the global burden of anemia.
- Trial name
- NCT03365570
- Where
- Egypt
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Cairo University
Dietary Diversity
A Feasibility Study of Delivering Adolescent Nutrition Interventions Through School-Based Platforms in Ethiopia
Alive \& Thrive (A\&T) is an initiative that supports the scaling up of nutrition interventions to save lives, prevent illnesses, and contribute to healthy growth and development through improved maternal nutrition, breastfeeding…
- Trial name
- NCT04121559
- Testing
- School Interventions, Community Interventions, School System Interventions
- Where
- United States
- Volunteers
- 1,712 people, healthy volunteers welcome
- Sponsor
- International Food Policy Research Institute
Breastfeeding
Implementation Strategy for a Breastfeeding Guideline in Primary Care
The purpose of this study is to determine whether an implementation strategy for a breastfeeding guide is more effective than the usual practice (simple circulation of the guide) in terms of increasing the percentage of children…
- Trial name
- NCT01474096
- Testing
- implementation strategy of Breastfeeding
- Where
- Spain
- Volunteers
- 208 people, healthy volunteers welcome
- Sponsor
- Gerencia de Atención Primaria, Madrid
Orthodontic Aligners
Difference Between Pressing and Vacuum Techniques in Fabrication of Orthodontic Aligners in Cases With Crowding: A Cross-sectional Study
This cross sectional study is aiming to compare 2 methods of clear aligner fabrication.
- Trial name
- NCT06231888
- Testing
- Aligner
- Where
- Egypt
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Cairo University
Healthy Volunteers
A Safety Study of Mebendazole in Children 2 to 10 Years of Age
The purpose of this study is to assess the safety and tolerability of mebendazole 500-mg chewable tablet formulation in a pediatric population.
- Trial name
- NCT01173562
- Testing
- Mebendazole
- Where
- Tanzania
- Volunteers
- 397 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Pharmaceutical Research & Development, L.L.C.
Calorie Consumption
Dietary and Cognitive Effects of Food Ads Posted by TikTok Influencers
Randomized and controlled experimental study to evaluate how influencer food ads on TikTok affect calorie purchases among youth (ages 10-13).
- Trial name
- NCT05777486
- Testing
- TikTok Ads - With Food, TikTok Ads - Without Food
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Convulsion, Non-Epileptic
Retraining and Control Therapy (ReACT): Sense of Control and Symptom Expectations as Targets of a Treatment for PNES
The purpose of this study is to assess sense of control and catastrophic symptom expectations as targets for Retraining and Control Therapy (ReACT- an intervention focused on changing behaviors and thoughts) for treatment of…
- Trial name
- NCT05096273
- Testing
- ReACT
- Where
- United States
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Autism Spectrum Disorder
Can a Novel Telemedicine Tool Reduce Disparities Related to the Identification of Preschool Children With Autism?
Families seeking evaluation for autism spectrum disorder (ASD) often face barriers such as low availability of specialists, lengthy waitlists, and long distances to tertiary care diagnostic centers.
- Trial name
- TAP-P (NCT05373173)
- Testing
- Tele-assessment + In-person assessment, Tele-assessment only
- Where
- United States
- Volunteers
- 148 people, healthy volunteers welcome
- Sponsor
- Vanderbilt University Medical Center
Falciparum Malaria
Phase Ib Trial of Two Virosome Formulated Malaria Vaccine Components (PEV 301, PEV 302) in Tanzania
This is a phase Ib double-blind randomized placebo controlled age-deescalating trial to assess sagety and immunogenicity of two virosome formulated anti-malaria vaccine components (PEV 301 and PEV 302) administered in combination…
- Trial name
- PMAL03 (NCT00513669)
- Testing
- PEV 301& 302 in virosomes, Inflexal V (active comparator)
- Where
- Tanzania
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Swiss Tropical & Public Health Institute
Tinnitus, Misophonia
Mindfulness Application Effects on Mental Health Symptoms in Children With Severe Tinnitus and Misophonia
Children with "bothersome" tinnitus and misophonia have elevated anxiety and depression symptoms. The mainstay therapy for adults and children with these disorders is cognitive behavioral therapy (CBT).
- Trial name
- NCT06493825
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Orthodontic Anchorage Procedures
Posterior Segment Intrusion Using Miniplates
Treating hyperdivergent malocclusion accompanied by open bite could be challenging and may be done by several methods as high pull headgear and posterior bite planes or surgically by maxillary impaction in adults.
- Trial name
- NCT02674191
- Testing
- mini-plates supported molar intrusion, Application of ULTRACARE benzocaine 20%,, Administration of , Mepivacaine-l
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Manal El Namrawy
Hyoid Bone
Impact of Twin Block and Motion Class II Appliances on Hyoid Bone Position - A Retrospective Clinical Study
Analyse the impact Twin block appliance and Motion on Hyoid Bone
- Trial name
- Hyoid bone (NCT06715774)
- Testing
- Impact of Twin Block and Motion above Hyoid bone
- Where
- Spain
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- University of Salamanca
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