Clinical trials: ACL Injuries
Anterior Cruciate Ligament Injury, ACL
Mechanical Perturbation Training for ACL Injury Prevention
A prospective trial will be used to evaluate the efficacy of prophylactic mechanical perturbation training program. 24 female athletes who are regular participants in activities that involve cutting, pivoting, jumping, and…
- Trial name
- NCT03080402
- Testing
- Mechanical Perturbation Training
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of Delaware
ACL, ACL Injury
Acupuncture ACL (Anterior Cruciate Ligament)
Acupuncture research in regards to PONV has been fairly well established, however, studies about perioperative pain control and acupuncture are a little more murky.
- Conditions
- ACL, ACL Injury, Anterior Cruciate Ligament Injury, Anterior Cruciate Ligament Rupture
- Trial name
- NCT03711734
- Testing
- Acupuncture + Standard of Care
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Hospital for Special Surgery, New York
Anterior Cruciate Ligament Injuries
Influence of Proprioceptive Reweighting Ability on Lower-limb Biomechanics During Functional Tasks
Anterior cruciate ligament (ACL) injuries are frequent in handball especially among young players. Recent investigations highlighted the implication of the central nervous system as a potential risk factor for ACL rupture.
- Trial name
- NEURIBIO (NCT04736511)
- Testing
- Star Excursion Balance Test, Single leg Drop Vertical Jump, Unplanned sidestep cutting manoeuvre
- Where
- France
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- University Hospital, Brest
Machine Learning
MUSCLE-ML: Multimodal Integration of Muscle Strength, Structure by Machine Learning for Precision Rehabilitation After ACL Injury
The goal of this clinical trial is to use machine learning (ML) to predict functional recovery by integrating muscle-related factors and other relevant parameters for identification of non-responders to conventional…
- Trial name
- NCT07284771
- Testing
- No Intervention: Observational Cohort
- Volunteers
- 182 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
Anterior Cruciate Ligament Rupture, Deficiency of Anterior Cruciate Ligament
Comparison of Three Methods for Anterior Cruciate Ligament Reconstruction
The purpose of this randomized clinical trial is to determine the difference in quality of life outcome at two years, in patients undergoing an Anterior Cruciate Ligament (ACL) reconstruction procedure with either a patellar…
- Conditions
- Anterior Cruciate Ligament Rupture, Deficiency of Anterior Cruciate Ligament, Chronic Instability of Knee, Anterior Cruciate Ligament Injury
- Trial name
- NCT00529958
- Testing
- Patellar Tendon, Hamstring Tendon, Double-Bundle
- Where
- Canada
- Volunteers
- 330 people, healthy volunteers welcome
- Sponsor
- University of Calgary
Sports Injury, Anterior Cruciate Ligament Rupture
Comparison of Functional Outcome Between BQT and SBHT ACL Reconstruction
ACL rupture has a high morbidity in productive-age population. The increasing incidence and proper management has become a point of interest in the musculoskeletal sport injury.
- Trial name
- BQTSBHTFMUI (NCT04536246)
- Testing
- Bone Quadriceps Tendon (BQT) arthroscopic-assisted ACL reconstruction, Single-Bundle Hamstring Tendon (SBHT) arthroscopic-assisted ACL reconstruction
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Universitas Indonesia
Anterior Cruciate Ligament Rupture
Return to Play After ACL Reconstruction With Bone Marrow Aspirate, DBM, and an Internal Brace
The Investigators are studying the effect of an ACL reconstruction on return to play by capturing outcome measures and biomechanics information.
- Trial name
- NCT06294314
- Testing
- Fertilized ACL
- Where
- United States
- Volunteers
- 450 people, healthy volunteers welcome
- Sponsor
- Marshall University
ACL Injury
Neuromuscular Training Improves Single-Limb Stability
Pretest/post-test study design, study will try to determine if a 6-week neuromuscular training program designed to decrease the incidence of anterior cruciate ligament (ACL) injuries would improve single-limb stability in young…
- Trial name
- NCT04967937
- Testing
- Strengthening, resistance exercise, plyometric and dynamic movement training
- Where
- Pakistan
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Riphah International University
ACL Injury Prevention
Effect of Specific ACL Injury Prevention Training in Female Handball Players
The anterior Cruciate Ligament (ACL) injuries rates in female handball are high, particularly among adolescents. Therefore, the primary purpose of this randomized control trial is to explore the effects of an 8-week ACL injury…
- Trial name
- NCT05955599
- Testing
- ACL Injury Prevention Training, Control - Shoulder Injury Prevention Training
- Where
- 3 sites in Denmark
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Copenhagen University Hospital, Hvidovre
Knee Injuries, Anterior Cruciate Ligament Injuries
Effect of Neuromuscular Warm-up on Injuries in Female Athletes
The goal of the study is to determine effect of coach-led neuromuscular warm-up on non-contact, lower extremity (LE) injury rates among female athletes in a predominantly non-white public high school system.
- Conditions
- Knee Injuries, Anterior Cruciate Ligament Injuries, Ankle Injuries, Lower Extremity Injuries
- Trial name
- NCT01092286
- Testing
- neuromuscular warm-up
- Where
- United States
- Volunteers
- 1,653 people, healthy volunteers welcome
- Sponsor
- Ann & Robert H Lurie Children's Hospital of Chicago
ACL Injury
Effectiveness of a Novel Warm-up in Decreasing Risk Factors for ACL Injury in Female Youth Soccer Players
There is a large number of young women who sustain serious knee injuries from playing soccer. Female athletes are at high risk of knee injuries from soccer than males.
- Trial name
- NCT01591941
- Testing
- Core-PAC
- Where
- Canada
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Rupture of Anterior Cruciate Ligament
Biomechanical Analysis of Dynamic Tasks and Muscular Strength Following Anterior Cruciate Ligament Reconstruction
Background Anterior cruciate ligament (ACL) injuries are one of the most common sporting injuries of the knee. ACL reconstruction (ACLR) has become one of the most common surgical procedures in an attempt to increase joint…
- Trial name
- NCT02771548
- Testing
- Anterior Cruciate Ligament Reconstruction
- Where
- Ireland
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Dr Neil Welch ASCC
Anterior Cruciate Ligament Injuries, Injuries, Knee
Effects Provided by a Physiotherapy Treatment Preventing Lower Extremity Injuries in Female Football Players
Background and justification: Women's football has a percentage of knee injury of 31.8%, and the anterior cruciate ligament lesion is between 2 and 4 times higher than the male.
- Conditions
- Anterior Cruciate Ligament Injuries, Injuries, Knee, Prevention & Control
- Trial name
- NCT04062578
- Testing
- Physiotherapy program of lumbopelvic stabilization and strengthening of the hip region musculature
- Where
- Spain
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Universidad de Zaragoza
Injury Prevention, Postural Balance
Effects of FIFA 11+ With Dynamic Core Stability Training on Balance and Dynamic Knee Valgus in Amateur Soccer Players
The incidence of soccer-related injuries is reported to have the highest rate amongst all sports. To reduce the incidence of soccer injuries in youth and amateur soccer players, an injury prevention framework namely FIFA 11+ was…
- Trial name
- NCT04958837
- Testing
- FIFA 11+ protocol with additional Core training exercises, FIFA 11+ protocol
- Where
- Pakistan
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Double Leg Vertical Jump (DLVJ), Single Leg Squat (SLS)
ESSKA/ESMA ACL Injury Prevention Program in Czech Sport
This study aims to address the rising incidence of ACL injuries, particularly among adolescents, by developing and implementing a comprehensive prevention program based on the evidence-based "ACL Prevention for ALL" framework…
- Conditions
- Double Leg Vertical Jump (DLVJ), Single Leg Squat (SLS), Single Leg Drop Landing (SLDL), Drop Jump Test (DJ Test)
- Trial name
- NCT07019727
- Testing
- ESSKA/ESMA 'ACL Prevention for All' methodology
- Where
- Czechia
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Masaryk University
ACL Injury
New Triple Hop Test Quality Assessment Tool
This study will develop a new jump assessment tool for the Triple Hop Test, and will test its reliability on adolescent and adult, healthy and post- anterior cruciate ligament (ACL) population.
- Trial name
- NCT04228848
- Testing
- new triple hop test
- Where
- Israel
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Haifa
Anterior Cruciate Ligament Rupture
Intra-articular Administration of 3.0g Tranexamic Acid Has no Effect on Reducing Intra-articular Hemarthrosis and Postoperative Pain After Primary Anterior Cruciate Ligament Reconstruction: A Randomized Controlled Trial
The purpose of this study was to investigate whether intraarticular administration of tranexamic acid could reduce hemarthrosis and postoperative pain in patients following anterior cruciate ligament reconstruction.
- Trial name
- NCT04042688
- Testing
- intraarticular administration of tranexamic acid
- Where
- South Korea
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- Korea University Guro Hospital
Anterior Cruciate Ligament Rupture
Comparison of Different Anterior Cruciate Ligament Surgery Techniques in Skeletally Immature Patients.
This cohort study compares to groups of patients with reconstruction of anterior cruciate ligament (ACL). Patients in group 1 had ACL-reconstruction in the years 2001-2010 with a transphyseal drilling technique.
- Trial name
- NCT04644497
- Testing
- ACL-reconstruction
- Where
- Denmark
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Aarhus University Hospital
ACL Tears
Characterizing Clinical and Biomechanical Contributions to Function Following ACL Reconstruction
Quantify differences in quadriceps function and gait biomechanics in individuals within 2 years of ACL reconstruction compared to a healthy comparison group and establish the feasibility of conducting a progressive strengthening…
- Trial name
- NCT03132987
- Testing
- Progressive strengthening program
- Where
- United States
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Creighton University
ACL Injury, ACL Reconstruction
Comparative Effectiveness of Blood Flow Restriction With or Without Total Motion Release in ACL Rehabilitation
The aim of this clinical trial is to compare the effectiveness of combined Blood Flow Restriction (BFR) and Total Motion Release (TMR) versus BFR alone in the restoration of muscular strength, balance and knee functionality in…
- Trial name
- BFR-TMR-ACL (NCT07589309)
- Testing
- Blood Flow Restriction, Total Motion Release
- Where
- Pakistan
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Green International University