Clinical trials: ACL Reconstruction
ACL Reconstruction
Effects of Anodal Transcranial Direct Current Stimulation on Muscle Inhibition After ACL Reconstruction
This randomized controlled trial will investigate the effects of anodal transcranial direct current stimulation (tDCS) on arthrogenic muscle inhibition in athletes following anterior cruciate ligament (ACL) reconstruction.
- Trial name
- NCT07866963
- Testing
- Anodal Transcranial Direct Current Stimulation (tDCS), Standard Physical Therapy
- Volunteers
- 64 people
- Sponsor
- University of Lahore
ACL Reconstruction
A Multi-centre, Double-blind RCT to Investigate the Effect of Alendronate on Knee Function Following ACLR
Anterior cruciate ligament (ACL) is the key ligament connecting the femur to tibia that helps stabilising the knee joint. ACL tear is common.
- Trial name
- NCT05527548
- Testing
- Alendronate (ALN)
- Where
- Hong Kong
- Volunteers
- 100 people
- Sponsor
- Chinese University of Hong Kong
Anterior Cruciate Ligament (Acl) Reconstruction
The Psychological Impact of Mindfulness Intervention to Anterior Cruciate Ligament Reconstruction
Anterior cruciate ligament (ACL) reconstruction surgery is a common procedure performed by orthopedic surgeons. Postoperatively, patients often experience pain, muscle tension, and concerns about their ability to return to…
- Trial name
- NCT06382324
- Testing
- mindfulness practice of body scan, listening to light music
- Where
- Taiwan
- Volunteers
- 80 people
- Sponsor
- Chang Gung Memorial Hospital
Anterior Cruciate Ligament (ACL) Reconstruction Surgery
Bioactive Knee Sleeves After ACL Reconstruction
This trial is studying the effectiveness of a bioactive knee sleeve to improve swelling and range of motion in the early postoperative ACL reconstruction.
- Trial name
- SLEEVE-ACL (NCT07707128)
- Testing
- Bioactive Knee Sleeve
- Where
- United States
- Volunteers
- 35 people
- Sponsor
- Western Kentucky Heart and Lung Research Foundation and Educational Trust
ACL Reconstruction
Methylprednisolone Addition to Multimodal Pain Regimens After Anterior Cruciate Ligament Reconstruction
Patients who are being seen for ACL tears will be approached in the UAB Orthopedic Clinic. Included patients will be those aged 14-65 undergoing ACL Reconstruction.
- Trial name
- NCT07605923
- Testing
- Methyl Prednisolone (MP), Standard Post-Operative Pain Control, Surgeon's Standard ACL Postoperative Regimen
- Where
- United States
- Volunteers
- 64 people
- Sponsor
- University of Alabama at Birmingham
ACL Injury, ACL Reconstruction
Comparative Effectiveness of Blood Flow Restriction With or Without Total Motion Release in ACL Rehabilitation
The aim of this clinical trial is to compare the effectiveness of combined Blood Flow Restriction (BFR) and Total Motion Release (TMR) versus BFR alone in the restoration of muscular strength, balance and knee functionality in…
- Trial name
- BFR-TMR-ACL (NCT07589309)
- Testing
- Blood Flow Restriction, Total Motion Release
- Where
- Pakistan
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Green International University
LET, ACL Reconstruction
Long-term Follow up of the Stability 1 Trial
From 2014-2017, across 7 Canadian and 2 European sites, we randomized 618 patients at high-risk of re-injury, to anterior cruciate ligament reconstruction (ACLR) with or without a lateral extraarticular tenodesis (LET) and…
- Conditions
- LET, ACL Reconstruction, Osteoarthritis (OA) of the Knee
- Trial name
- STABILITY LTF (NCT06885372)
- Testing
- Lateral Extra-Articular Tenodesis (LET), ACL Reconstruction
- Where
- 8 sites in Canada, United Kingdom
- Volunteers
- 510 people
- Sponsor
- Western University, Canada
Anterior Cruciate Ligament Reconstruction Rehabilitation, Strength Outcomes
Effect of Graft Type on Knee Muscle Strength After ACL Reconstruction
This prospective observational study will compare recovery after anterior cruciate ligament reconstruction using quadriceps tendon autograft or hamstring tendon autograft.
- Conditions
- Anterior Cruciate Ligament Reconstruction Rehabilitation, Strength Outcomes, Anterior Cruciate Ligament (ACL) Reconstruction Surgery
- Trial name
- GRAFT-ACL (NCT07523854)
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Hacettepe University
Anterior Cruciate Ligament (ACL) Reconstruction, Anterior Cruciate Ligament Injury
Comparison of Bone-patellar Tendon-bone and Patellar Tendon-bone Grafts in ACL Reconstruction
The purpose of this randomized study is to compare donor site morbidity and clinical and functional outcomes of both surgery techniques (bone-patellar tendon-bone (BPTB) graft versus bone-patellar tendon without patellar bone…
- Trial name
- NCT07475351
- Testing
- Bone-Patellar tendon-Bone, Patellar tendon-Bone
- Where
- Spain
- Volunteers
- 110 people
- Sponsor
- Universidad de Granada
ACL Reconstruction, ACL Surgery
Post Operative Use of Neuromuscular Electrical Stimulation (NMES) Device for ACLR Patients
This study is being conducted to learn about how neuromuscular electrical stimulation (NMES) in addition to standard of care aids in the recovery of muscle strength in patients undergoing ACLR procedure.
- Conditions
- ACL Reconstruction, ACL Surgery, ACL Injury, Electrotherapy
- Trial name
- NCT07171346
- Testing
- Zynex NexWave Electrotherapy Device
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- University of Kansas Medical Center
ACL Reconstruction
Readiness Outcomes Affecting Return to Sport 3.0
The primary aim is to determine if MST will improve coping skills in young athletes returning to sport after ACLR as measured by ACSI-28.
- Trial name
- ROAR 3 (NCT07476430)
- Testing
- Mental Skills Training (MST)
- Where
- United States
- Volunteers
- 130 people
- Sponsor
- Boston Children's Hospital
Rehabilitation, ACL Reconstruction
Neuromuscular Intervention Targeted to Mechanisms of ACL Load in Female Athletes
The overall goal of this project is to reduce risk of second anterior cruciate ligament (ACL) injury in vulnerable populations (active athletes between 14 = 24 years old) through the identification of relative injury risk groups…
- Trial name
- NCT03190889
- Testing
- HOME, TNMT
- Where
- 4 sites in United States
- Volunteers
- 150 people
- Sponsor
- Mayo Clinic
ACL Surgery, ACL Injuries
Developing and Validating the Risk-taking Intention and Sport Engagement After ACL Reconstruction (RISE-ACL) Scale
Psychological factors play a critical role in recovery following anterior cruciate ligament (ACL) reconstruction. While tools such as the ACL - Return to Sport after Injury (ACL-RSI) focus on psychological readiness, emphasizing…
- Conditions
- ACL Surgery, ACL Injuries, ACL Reconstruction
- Trial name
- RISE-ACL (NCT06748066)
- Testing
- RISE-ACL development, RISE-ACL scale validation
- Where
- France
- Volunteers
- 162 people
- Sponsor
- University Hospital, Caen
ACL Reconstruction, Meniscus Tears
A Comparison of Outcomes After Anterior Cruciate Ligament (ACL) or Anterior Cruciate Ligament and Meniscus (ACL+Meniscus) Surgery Using Semiconductor Fabric Products
The goal of this clinical trial is to determine the effect of semiconductor sleeves on the treatment of Anterior Cruciate Ligament (ACL) or Anterior Cruciate Ligament and Meniscus (ACL+Meniscus) arthroscopic surgery.
- Conditions
- ACL Reconstruction, Meniscus Tears, Anterior Cruciate Ligament Rupture
- Trial name
- NCT06979804
- Testing
- Semiconducting fabric sleeves, Non-semiconducting fabric sleeves
- Where
- United States
- Volunteers
- 135 people
- Sponsor
- Illinois Center for Orthopaedic Research and Education
ACL Reconstruction
Protein Supplementation After ACL Surgery
The purpose of the study is to assess the longitudinal post-operative care effects of protein supplementation on muscle atrophy in the post-operative period following ACL reconstruction.
- Trial name
- NCT06311058
- Testing
- Whey protein isolate, Protein + BAA
- Where
- United States
- Volunteers
- 102 people
- Sponsor
- The Methodist Hospital Research Institute
ACL Reconstruction, Cognitive Function
Test of Return to Sport After ACL Reconstruction and Cognitive Task.
After reconstruction of the anterior cruciate ligament, the aim for the vast majority of sportspeople is to return to the field.
- Conditions
- ACL Reconstruction, Cognitive Function, Single Leg Hop Firm Surface, Testing Effect of Intervention
- Trial name
- AQQSHTATC (NCT06768957)
- Testing
- Single leg hop for distance, Single leg hop for distance plus cognitive task
- Where
- 4 sites in France
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- Simon VALOT
Quadriceps Atrophy, ACL Reconstruction
Does Blood Flow Restriction Training Improve Quadriceps Function After Arthroscopic Knee Surgery?
The purpose of this study is to evaluate the effectiveness of physical therapy (PT) plus BFR training compared to PT alone (without BFR training) after ACL reconstruction in patients who require extended limited weight bearing…
- Trial name
- NCT03096366
- Testing
- Blood flow restriction, Physical therapy
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- The University of Texas Health Science Center, Houston
ACL Reconstruction
When do School-aged Patients Return to School After ACL Surgery?
We intend to survey school aged patients following ACL surgery on when they return to school. We will analyze independent variables to determine if any relationship exists that may influence the amount of time missed.
- Trial name
- NCT03929237
- Testing
- observe when return to school after surgery
- Where
- 2 sites in United States
- Volunteers
- 58 people
- Sponsor
- St. Louis University
Anterior Cruciate Ligament (ACL) Reconstruction
Gabapentin Premedication for ACL Reconstruction: RCT
This double blind randomized control trial will enroll 100 participants ages 12-18 years, undergoing ACL repair. Participants receive gabapentin or placebo preoperatively.
- Trial name
- NCT03417479
- Testing
- Gabapentin
- Where
- United States
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- Children's Healthcare of Atlanta
ACL Reconstruction
Transphyseal Vs. Physeal Sparing ACL Reconstruction in Skeletally Immature Patients: Risk of Subsequent Lower Extremity Growth Deformity
To assess the risk of lower extremity angular growth deformity following anterior cruciate ligament (ACL) reconstructions in young patients who are not yet skeletally mature.
- Trial name
- NCT03081026
- Testing
- Bilateral hip to ankle x-ray, exam and strength testing.
- Where
- United States
- Volunteers
- 49 people
- Sponsor
- Duke University