Clinical trials: ACT
Cerebral Palsy
Safety and Effectiveness of Banked Cord Blood or Bone Marrow Stem Cells in Children With Cerebral Palsy (CP).
The purpose of this study is to compare the safety and effectiveness of two types of stem cells,(either banked cord blood or bone marrow), in children between the ages of 2 to 10 years with CP.
- Trial name
- ACT for CP (NCT01988584)
- Testing
- umbilical cord blood (hUCB) cells, bone marrow derived mononuclear cells (BMMNCs)
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- The University of Texas Health Science Center, Houston
Typhoid Fever
The Azithromycin and Cefixime Treatment of Typhoid in South Asia Trial (ACT-South Asia Trial)
Typhoid and paratyphoid (enteric) fever affects more than 11 million children and adults globally each year including 7 million in South Asia.
- Trial name
- ACT-South Asia (NCT04349826)
- Testing
- Azithromycin, Cefixime
- Where
- Nepal
- Volunteers
- 2,150 people
- Sponsor
- Oxford University Clinical Research Unit, Vietnam
Autism Spectrum Disorder
ACT Combined Yoga for Parental Burnout in Parents with Autistic Children
OBJECTIVE: To explore the intervention effect of ACT combined with a yoga intervention program on parenting burnout in parents with ASD.
- Trial name
- NCT06348992
- Testing
- Acceptance commitment therapy and yoga, Active Comparator: Mental Health Education Group
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Harbin Medical University
Depression, Trauma
Online Therapy Youth, Equivalent to Treatment As Usual?
With growing waiting lists in specialized youth mental health care (sGGZ) and shortages of care staff, finding creative solutions to respond to this scarcity issue is important.
- Conditions
- Depression, Trauma, Compulsive Disorder, Anxiety
- Trial name
- NCT06617663
- Testing
- EMDR, ACT
- Where
- Netherlands
- Volunteers
- 172 people, healthy volunteers welcome
- Sponsor
- GGZ Noord-Holland-Noord
Multiple Injuries of Hand (Disorder)
The Efficacy of Hand Injuries Rehabilitation Intervention Program That Incorporated Ethnic and Cultural Reference
The study has three main phases. The first phase included A. Adjustment of research tools. Phase B. will examine the efficacy of the cultural intervention. Phase C.
- Trial name
- NCT05891704
- Testing
- Hand therapy Rehabilitation intervention program that incorporate cultural reference, Conventional Hand therapy Rehabilitation intervention program
- Where
- Palestinian Territories
- Volunteers
- 100 people
- Sponsor
- Tel Aviv University
Alpha-1 Antitrypsin Deficiency
The Alpha-1 Foundation's and University of Florida's Alpha-1 Coded Testing (ACT) Study
The Alpha-1 Coded Testing (ACT) Study was established to study genetic testing and outcomes of individuals at risk for alpha-1 antitrypsin deficiency.
- Trial name
- ACT (NCT00500123)
- Testing
- Alpha-1 Antitrypsin Genotype
- Where
- United States
- Volunteers
- 50,000 people, healthy volunteers welcome
- Sponsor
- University of Florida
Malaria, Burkina Faso
Evaluation of Three Artemisinin-based Combinations for the Treatment of Uncomplicated Malaria in Childreen in Burkina Faso (CHIMIO2)
Bakground In Burkina Faso, since the adoption of this new malaria treatment policy in 2005, several studies evaluating the efficacy and tolerance of ACTs have been carried out by different research teams at different sites…
- Trial name
- CHIMIO2 (NCT04778813)
- Testing
- Artemether-lumefantrine
- Where
- Burkina Faso
- Volunteers
- 1,050 people
- Sponsor
- Centre national de recherche et de formation sur le paludisme
Very Premature Baby
Attention Control Training (ACT) and Very Preterm Infants
Infants' attention control, defined as the ability to select what to pay attention to, is a fundamental building block for developing learning abilities and behaviour self-regulation.
- Trial name
- ACT (NCT03896490)
- Testing
- Attention Control Training, Control
- Where
- United Kingdom
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Queen's University, Belfast
Asthma
Efficacy of Educational Intervention for Parents of Children With Asthma
Introduction. Asthma is a chronic inflammatory disorder of the airways, identified by airflow obstruction. Unfortunately only 2.4% of American asthmatics meet internationally recommended criteria for control.
- Trial name
- NCT01979224
- Testing
- Educational intervention for parents
- Volunteers
- 42 people
- Sponsor
- Universidad Autonoma de San Luis Potosí
Malaria, Falciparum
Study to Compare the Triple ACT AL+AQ With the ACT AL in Cambodia and Vietnam
This study is a multi-centre, open-label randomised trial to assess the efficacy, safety and tolerability of the Triple ACT artemether-lumefantrine+amodiaquine (AL+AQ) compared to the ACT artemether-lumefantrine (AL) in…
- Trial name
- TACT-CV (NCT03355664)
- Testing
- ACT, TACT
- Where
- 4 sites in Cambodia, Vietnam
- Volunteers
- 310 people
- Sponsor
- University of Oxford
Malaria, Anaemia
IMPACT2: Monitoring Interventions to Improve Artemisinin-based Combination Therapy (ACT) Access and Targeting
It is generally agreed that artemisinin-based combination therapy (ACT) is the malaria therapy of choice but there is much less agreement about the best ACT-deployment strategies.
- Trial name
- IMPACT2 (NCT01130155)
- Where
- Tanzania
- Volunteers
- 33,900 people, healthy volunteers welcome
- Sponsor
- London School of Hygiene and Tropical Medicine
Malaria
Pyronaridine Artesunate (3:1) Versus Coartem® in P Falciparum Malaria Patients
The primary objective of this phase III study is to compare the efficacy and safety of the fixed combination of pyronaridine artesunate (Pyramax®, PA) with that of Coartem® (artemether lumefantrine, AL) in children and adults…
- Trial name
- NCT00422084
- Testing
- Pyronaridine artesunate, Coartem® (artemether lumefantrine)
- Where
- 10 sites in Democratic Republic of the Congo, Ghana and 7 more
- Volunteers
- 1,272 people
- Sponsor
- Medicines for Malaria Venture
Social Anxiety Disorder, Generalized Anxiety Disorder
Where We All Meet: ACT Approach to Adolescents Anxiety Disorders
Transdiagnostic approaches have been proposed as more truthfully representing mental health problems. Acceptance and Commitment Therapy (ACT) is a transdiagnostic approach that proposes Psychological Inflexibility/Flexibility…
- Trial name
- NCT05906849
- Testing
- ACT for anxiety disorders
- Where
- Portugal
- Volunteers
- 87 people, healthy volunteers welcome
- Sponsor
- University of Coimbra
Malaria, Pneumonia
Assessment of Use of Rapid Diagnostic Testing in the Context of Home Management With ACTs
This study is to assess the value of incorporating a malaria RDT based strategy in HMM. The primary activity of the study wil be a two armed cluster randomised trial in two study sites in Uganda, one in Ghana and one in Burkina…
- Trial name
- NCT00720811
- Testing
- Artemether-lumefantrine combination, amoxycillin, paracetamol
- Where
- 4 sites in Burkina Faso, Ghana and 1 more
- Volunteers
- 6,456 people
- Sponsor
- Mbarara University of Science and Technology
HIV/AIDS
Adolescent Coordinated Transition Nigerian HIV+ Youth
The purpose of this study is to evaluate the comparative effectiveness of a comprehensive, coordinated transition protocol which includes an early introduction to the adult provider, an integrated case management team and a…
- Trial name
- ACT (NCT03152006)
- Testing
- ACT
- Where
- 5 sites in Nigeria
- Volunteers
- 216 people
- Sponsor
- University of Nevada, Las Vegas
Students With Disabilities and/or Family Members With Students With Disabilities That Have a Section 504 Plan
Randomized Controlled Trial Testing a Training Program About Section 504 of the Rehabilitation Act
The goal of this training program is to learn if the intervention (i.e., training program) can improve access to Section 504 among students with disabilities and family caregivers.
- Trial name
- NCT07710300
- Testing
- Treatment, Materials-only control condition
- Where
- United States
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Vanderbilt University
Plasmodium Falciparum, Malaria
Efficacy of Artesunate-amodiaquine and Artemether-lumefantrine for Treatment of Plasmodium Falciparum Malaria in Liberia
To assess the efficacy of both first-line antimalarial medications used for the treatment of uncomplicated Plasmodium falciparum malaria infections in two geographic regions in Liberia.
- Conditions
- Plasmodium Falciparum, Malaria, Uncomplicated Malaria
- Trial name
- NCT06300970
- Testing
- Amodiaquine-artesunate (ASAQ), Artemether+Lumefantrine (AL)
- Where
- 2 sites in Liberia
- Volunteers
- 352 people
- Sponsor
- Centers for Disease Control and Prevention
Obesity
Evaluation of California's SB 19 Pupil Nutrition Act
Four California school districts will be randomized to early implementation of California's SB 19 Pupil Nutrition Act or to business as usual.
- Trial name
- NCT00067847
- Testing
- State-directed nutrition policy change
- Where
- United States
- Volunteers
- 5,020 people, healthy volunteers welcome
- Sponsor
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Malaria
Artemisinin-Based Antimalarial Combinations and Clinical Response in Cameroon
To assess the efficacy of artesunate-amodiaquine, dihydroartemisinin-piperaquine, in comparison with artemether-lumefantrine during 42 days follow up period in 720 children with acute uncomplicated P.
- Trial name
- NCT01845701
- Testing
- Artesunate-Amodiaquine, Dihydroartemisinine-Piperaquine, Artemether-lumefantrine combination
- Where
- 2 sites in Cameroon
- Volunteers
- 720 people
- Sponsor
- University of Yaounde 1
Encephalopathy, Cerebral Palsy
Initiating Pediatric Palliative Care in ACT Group 4
Due to the wide range of diagnoses encountered in pediatric palliative care, the Association for Children's Palliative Care (ACT) and the Royal College of Paediatrics and Child Health (RCPCH) have developed a classification of…
- Conditions
- Encephalopathy, Cerebral Palsy, Cerebral Malformation, Traumatic Head Injury
- Trial name
- StartSPP (NCT06273267)
- Testing
- Collection of data from the patient's medical file
- Where
- France
- Volunteers
- 126 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris