Clinical trials: AI
Gastrointestinal Issues, Respiratory Issues
Real-world Observation of Medical Accuracy of a Novel AI-app
This study aims to evaluate the performance of the suggestions made by the WRA by comparing Ada's list of suggested conditions and advice level to usual care and a gold-standard in a Romanian clinical setting.
- Conditions
- Gastrointestinal Issues, Respiratory Issues, Cardiovascular Issues, Genitourinary Issues
- Trial name
- ROMAN-AI (NCT05194215)
- Testing
- Ada WRA
- Where
- Romania
- Volunteers
- 49 people
- Sponsor
- Ada Health GmbH
Pediatric, Adenotonsillectomy
AI-Generated Maternal Voice Storytelling During Pediatric Adenotonsillectomy
This prospective, three-arm randomized controlled trial aims to evaluate the effects of AI-generated maternal voice storytelling on the perioperative stress response, emergence delirium, anesthetic requirements, and perioperative…
- Trial name
- NCT07706725
- Testing
- AI-Generated Maternal Voice Storytelling, Relaxing Instrumental Music, midazolam premedication
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Adiyaman University Research Hospital
Clinician Experience, Clinician Burnout
Abridge AI Pilot Test
We are piloting a new technology (Abridge) that uses artificial intelligence to listen to clinician-patient office visits and then document the interaction in the electronic health record.
- Trial name
- NCT06778148
- Testing
- Ambient AI for clinician documentation
- Where
- United States
- Volunteers
- 232 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Type 1 Diabetes
The Pediatric Artificial Pancreas Automated Initialization Trial
The goal of this clinical trial is to obtain safety data and exploratory glycemic control data from use of an at-home closed loop control (CLC) system (t:slim X2 with Control-IQ Technology) with periodic parameter adjustments…
- Trial name
- PEDAP-AI (NCT06017089)
- Testing
- AI-based Advisor system
- Where
- 3 sites in United States
- Volunteers
- 33 people
- Sponsor
- Marc Breton
Urinary Stones, Prostate Cancer
Development of an AI-Agent for Urological Disease Diagnosis and Treatment
Urological diseases such as urinary stones, prostate cancer, and bladder cancer are very common and often require highly specialized diagnosis and treatment.
- Conditions
- Urinary Stones, Prostate Cancer, Bladder Cancer
- Trial name
- NCT07721935
- Where
- 3 sites in China
- Volunteers
- 2,000 people
- Sponsor
- Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
Healthy
Building an AI to Infer/Predict an Estimated Stool Microbiome Profile
This is a study to collect data to build, evaluate and validate (test) a tool to infer/predict an estimated microbiome (community of microorganisms such as bacteria, fungi and viruses that exists in a particular environment)…
- Trial name
- Poobiome (NCT05847543)
- Testing
- Stool diaper data and sample collection
- Where
- 4 sites in Malaysia, Singapore and 1 more
- Volunteers
- 440 people, healthy volunteers welcome
- Sponsor
- Danone Asia Pacific Holdings Pte, Ltd.
Intubation Performance Using AI Versus Conventional Videolaryngoscope in a Mannikin
AI-assisted Endotracheal Intubation
This study evaluates artificial intelligence (AI)-assisted videolaryngoscopy for endotracheal intubation in a simulated pediatric airway environment.
- Trial name
- NCT07508826
- Testing
- AI-assisted videolaryngoscopy, Conventional Intubation
- Where
- Canada
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- The Hospital for Sick Children
Behavior Problem of Childhood and Adolescence, Parent Management Training
Behavioral Parent Training With and Without AI Support for Children With Disruptive Behaviors
The goal of this clinical trial is to learn if adding an artificial intelligence (AI) application called to standard Behavioral Parent Training (BPT) helps families with children who have disruptive behavior problems.
- Conditions
- Behavior Problem of Childhood and Adolescence, Parent Management Training, Artificial Intelligence (AI), Disruptive Behaviours
- Trial name
- NCT07469215
- Testing
- Behavioral Parent Training (BPT), Behavioral Parent Training (BPT) + Support of AI app
- Where
- Spain
- Volunteers
- 40 people
- Sponsor
- Fundació Sant Joan de Déu
Atopic Dermatitis, Psoriasis
Cosmetic Efficacy Evaluation of Hydraporin AI Cream in Individuals With Atopic Dermatitis and Psoriasis
The goal of this clinical trial is to evaluate the cosmetic efficacy and safety of an investigational cream in participants with atopic dermatitis or psoriasis.
- Trial name
- NCT07918560
- Testing
- Investigational cream
- Where
- Brazil
- Volunteers
- 42 people
- Sponsor
- Brainfarma Industria Química e Farmacêutica S/A
Chronic Adrenal Insufficiency
A European Post-Authorisation Observational Study (Registry) of Patients With Chronic Adrenal Insufficiency (AI)
As a post-approval requirement of the European Medicines Agency, this European patient post authorization safety study is an observational study being conducted to monitor the safety of long-term treatment with Plenadren and…
- Trial name
- NCT01661387
- Where
- 24 sites in Germany, Italy and 3 more
- Volunteers
- 3,258 people
- Sponsor
- Shire
Adolescent Idiopathic Scoliosis (AIS)
AI-Based Digital Therapeutics vs. Traditional Schroth Exercises for Adolescent Idiopathic Scoliosis
This randomized controlled trial (RCT) evaluates the efficacy of a novel Artificial Intelligence (AI)-based digital therapeutic system compared to traditional outpatient Schroth exercises for the treatment of Adolescent…
- Trial name
- AIS-DTx-RCT (NCT07341633)
- Testing
- AI-Based Digital Therapeutic System, Standard Outpatient Schroth Therapy
- Where
- China
- Volunteers
- 300 people
- Sponsor
- Jinan University Guangzhou
Abdominal Pain, Pelvic Pain
Assess Patient Readiness for Pelvic Ultrasound With the Use of Artificial Intelligence
Point-of-Care Ultrasound (POCUS) is a relatively quick and non-invasive technique to assess bladder fullness which will be provided under standard of care.
- Trial name
- AI-POCUS (NCT07535294)
- Testing
- Experimental AI POCUS, Standard of Care Ultrasound
- Where
- United States
- Volunteers
- 520 people
- Sponsor
- Nicklaus Children's Hospital f/k/a Miami Children's Hospital
Colorectal Cancer Metastatic, Colorectal Cancer Stage III
COLONYVAQ™, a Quantum-Classical Guided Personalized Neoantigen Vaccine for MSS Stage III Colorectal Cancer
This is an early phase I, single-arm, open-label clinical study designed to evaluate the safety, tolerability, and feasibility of COLONYVAQ-CRC, a physics-aware, quantum-classical AI-guided personalized neoantigen peptide…
- Conditions
- Colorectal Cancer Metastatic, Colorectal Cancer Stage III, Colorectal Cancer Stage IV
- Trial name
- COLONYVAQ™-CRC (NCT07328087)
- Testing
- Experimental: COLONYVAQ-CRC + mFOLFOX6 or CAPOX + Nivolumab
- Where
- Greece
- Volunteers
- 12 people
- Sponsor
- Biogenea Pharmaceuticals Ltd.
Orthodontic Relapse
The Use of Remote Monitoring for Orthodontic Retention Review
To assess whether using retainers and an artificial intelligence supported remote monitoring system maintains a more stable orthodontic treatment result than using retainers with in-office review appointments.
- Trial name
- NCT05006339
- Testing
- Dental Monitoring, Clinic Review
- Where
- Australia
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- Sydney Local Health District
Chronic Pancreatitis, Exocrine Pancreatic Insufficiency
AI Evaluation of Pancreatic Exocrine Insufficiency in CP Patients
Early assessment of pancreatic exocrine insufficiency (PEI) is crucial for determining appropriate chronic pancreatitis (CP) treatment plans, thereby avoiding unnecessary suffering and further complications in patients.
- Conditions
- Chronic Pancreatitis, Exocrine Pancreatic Insufficiency, Machine Learning, Deep Learning
- Trial name
- NCT06278272
- Where
- China
- Volunteers
- 504 people
- Sponsor
- Changhai Hospital
Clinical Documentation, Artificial Intelligence
Ambient Audio-Visual Capture for Clinical Documentation and Assessment
AI-powered tools that automatically document clinical conversations are being adopted rapidly in outpatient settings but have not been evaluated in hospital wards.
- Conditions
- Clinical Documentation, Artificial Intelligence, Surgical Education, Medical Education
- Trial name
- BLACKFRAME-AV- (NCT07649772)
- Testing
- BlackFrame ambient audio-visual capture platform
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- BlackFrame.ai
Artifical Intelligence, Generative Artificial Intelligence
AI-Driven Video Avatars vs. Customized GPTs: Professional English Learning Among Nursing Students
The goal of this study is to evaluate and compare the effectiveness of two generative artificial intelligence technologies (an interactive AI video avatar vs.
- Conditions
- Artifical Intelligence, Generative Artificial Intelligence, Education, Nursing Students
- Trial name
- NCT07897422
- Testing
- Interactive AI Video Avatar, Personalized GPT Interface
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Manisa Celal Bayar University
Medical Informatics Applications
Real-world Effectiveness Evaluation of Clinical Decision Support System Based on Artificial Intelligence (AI-CDSS)
This study intends to explore the accuracy of clinical diagnosis of AI based CDSS system and promotion of clinical work by comparing CDSS before and after the online.
- Trial name
- NCT05065931
- Testing
- Auxiliary diagnostic system by AI-CDSS
- Where
- China
- Volunteers
- 34,113 people
- Sponsor
- Peking University Third Hospital
Pre-myopia, Myopia
Managing Premyopia in Chinese Children Using Artificial Intelligence Assisted Defocus Incorporated Multiple Segments Based Spectacle Lens: a Randomized Controlled Clinical Trial
Pre-myopia refers to a condition in which children have not yet developed myopia but exhibit insufficient hyperopic reserve (≤ +0.75 D).
- Trial name
- NCT07765550
- Testing
- Artificial Intelligence Assisted DIMS based Spectacle Lens, Smartwatches
- Where
- China
- Volunteers
- 128 people
- Sponsor
- Shanghai Eye Disease Prevention and Treatment Center
COPD
DYNAMIC AI: Digital Innovation With Remote Management and Predictive Modelling to Integrate COPD Care With Artificial Intelligence-based Insights: An Acceptability, Feasibility and Safety Study
DYNAMIC AI is an MHRA-regulated medical device trial that will examine the feasibility of using AI predictive models within COPD multi-disciplinary team meetings, to allow clinicians to prioritise and optimise COPD management.
- Trial name
- DYNAMIC AI (NCT05914220)
- Testing
- AI Insights Application
- Where
- United Kingdom
- Volunteers
- 500 people
- Sponsor
- NHS Greater Glasgow and Clyde