Clinical trials: ARDS, Human
Respiratory Distress Syndrome, Respiratory Distress Syndrome, Adult
Identifying PARDS Endotypes
Pediatric acute respiratory distress syndrome (PARDS) is a severe and diffuse lung injury that is a common cause of admission and mortality in the pediatric intensive care unit (PICU).
- Trial name
- NCT03539783
- Testing
- Respiratory epithelial cell brushing
- Where
- 2 sites in United States
- Volunteers
- 76 people
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Pulmonary Contusion, Respiratory Failure
Relationship of Pulmonary Contusion to Pulmonary Inflammation and Incidence of Acute Respiratory Distress Syndrome
Pulmonary contusion (PC) is a significant problem after blunt trauma that may often lead to acute respiratory distress syndrome (ARDS) and in some patients, death.
- Conditions
- Pulmonary Contusion, Respiratory Failure, ARDS
- Trial name
- NCT02265198
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Wake Forest University Health Sciences
Acute Lung Injury, Acute Respiratory Distress Syndrome
ALI (Acute Lung Injury) /ARDS (Acute Respiratory Distress Syndrome) in Oncologic Pediatric Patients
Identify pediatric oncologic patients with ALI/ARDS at GRAACC (Grupo de Apoio ao Adolescente e a Criança com Câncer) /IOP's (Instituto de Oncologia Pediátrica) Pediatric Intensive Care Unit and evaluate the mechanical ventilation…
- Conditions
- Acute Lung Injury, Acute Respiratory Distress Syndrome, Neoplasms
- Trial name
- NCT01304654
- Where
- Brazil
- Volunteers
- 29 people
- Sponsor
- Grupo de Apoio ao Adolescente e a Crianca com Cancer
Pediatric Acute Respiratory Distress Syndrome, Extracorporeal Membrane Oxygenation
Prone Position During ECMO in Pediatric Patients With Severe ARDS
In 2023, the second Pediatric Acute Lung Injury Consensus Conference (PALICC-2) updated the diagnostic and management guidelines for Pediatric Acute Respiratory Distress Syndrome (PARDS).
- Trial name
- PEPAD (NCT06369584)
- Testing
- prone position
- Where
- 8 sites in China
- Volunteers
- 7 people
- Sponsor
- Seventh Medical Center of PLA General Hospital
ARDS
Retrospective Postoperative ARDS Study at Vanderbilt University
By examining the intraoperative anesthetic characteristics of patients who developed ARDS postoperatively, we hope to identify variables which have a positive or negative association on the development of ARDS.
- Trial name
- NCT00656071
- Where
- United States
- Volunteers
- 89 people
- Sponsor
- Vanderbilt University
Bronchiolitis, Pneumonia
National Observatory of Children Hospitalized for Acute Respiratory Distress or Lower Respiratory Tract Infections
This study is an observational, multicenter and prospective study for surveillance of case of hospitalised children acute respiratory distress or lower respiratory tract infections
- Conditions
- Bronchiolitis, Pneumonia, Asthma
- Trial name
- OVNI (NCT06112132)
- Where
- France
- Volunteers
- 1,827 people
- Sponsor
- Association Clinique Thérapeutique Infantile du val de Marne
Respiratory Distress Syndrome in Premature Infants
First In Human Study on Synthetic Surfactant CHF 5633 in Respiratory Distress Syndrome
The aim of this study is to investigate the safety and tolerability of intratracheal administration of two different single doses of CHF 5633 in preterm neonates with RDS in terms of adverse events, adverse drug reactions…
- Trial name
- NCT01651637
- Testing
- synthetic surfactant (CHF5633)
- Where
- United Kingdom
- Volunteers
- 40 people
- Sponsor
- Chiesi Farmaceutici S.p.A.
Acute Respiratory Distress Syndrome
PEEP Test and Gas Exchange in ALI/ARDS Patients
The investigators aim to study the effect of different levels of PEEP in ALI/ARDS patients on gas exchange.
- Trial name
- NCT00284102
- Testing
- Mechanical ventilation
- Where
- Italy
- Volunteers
- 50 people
- Sponsor
- Policlinico Hospital
Child, Only, Infant, Newborn, Diseases
Capnography Monitoring in Ventilated Children
End-tidal CO2 measurements in children will be assessed for their accuracy with arterial CO2 measurements.
- Conditions
- Child, Only, Infant, Newborn, Diseases, Critical Illness, ARDS, Human
- Trial name
- NCT04354220
- Testing
- capnography monitoring, arterial blood gas
- Where
- Switzerland
- Volunteers
- 178 people, healthy volunteers welcome
- Sponsor
- Vincenzo Cannizzaro
Pediatric Acute Respiratory Distress Syndrome (PARDS)
Role of Dyspnea in the Progression of Pediatric Acute Respiratory Distress Syndrome
Pediatric acute respiratory distress syndrome (ARDS) is a life-threatening clinical syndrome, and dyspnea is its key symptom. Strenuous respiratory effort is a "second hit" for ARDS lungs, inducing changes in regional lung…
- Trial name
- NCT07750288
- Testing
- Noninvasive respiratory support, Transition from controlled to assisted mechanical ventilation, Weaning from mechanical ventilation
- Where
- Chile
- Volunteers
- 68 people
- Sponsor
- Universidad Nacional Andres Bello
Pressure Ulcer, Skin Lesion
Prevention of Skin Damage in the Patient in Prone Position: Development of Education Interventions Based on a Training Needs Assessment Study.
This is study 1 of 3 - of the overall project: The ProneTection Quality Improvement Project. The three aims of this study, study 1 are: 1.
- Conditions
- Pressure Ulcer, Skin Lesion, Acute Respiratory Distress Syndrome
- Trial name
- NCT05238870
- Testing
- Interviews for the needs analysis. No intervention.
- Where
- 2 sites in Belgium
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- University Ghent
Acute Respiratory Distress Syndrome, Lung Diseases
Corticosteroids as Rescue Therapy for the Late Phase of Acute Respiratory Distress Syndrome
The purpose of this study is to assess innovative treatment methods in patients with adult respiratory distress syndrome (ARDS) as well as those at risk of developing ARDS.
- Trial name
- NCT00295269
- Testing
- Mythylprednisolone
- Volunteers
- 200 people
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Respiratory Failure
Closed-Loop O2 Use During Invasive Mechanical Ventilation Of Pediatric Patients
During mechanical ventilation (MV) hypoxemic or hyperoxemic events should be carefully monitored and a quick response should be provided by the caregiver at the bedside.
- Trial name
- CLOUDIMPP (NCT05714527)
- Testing
- Close-loop FiO2 controller, Conventional
- Where
- 4 sites in Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Dr. Behcet Uz Children's Hospital
COVID-19, ARDS, Human
The Critical Care Response to the COVID-19 Pandemic in Madrid
Description of the adaptation of ICUs in the region of Madrid to que surge in demand of critical care due to COVID-19
- Trial name
- Tetrix (NCT04393324)
- Where
- Spain
- Volunteers
- 2,500 people, healthy volunteers welcome
- Sponsor
- Hospital San Carlos, Madrid
Acute Respiratory Failure, Pediatric Respiratory Distress Syndrome
Closed-loop Synchronization Versus Conventional Synchronization
A prior research indicated that asynchrony between the patient and ventilator occurred in 33 percent of 19,175 breaths, and was seen in every patient.
- Trial name
- CHESTSIPP (NCT05731024)
- Testing
- close-loop synchronization controller with SPONT mode, Conventional synchronization settings with SPONT mode
- Where
- 5 sites in Turkey (Türkiye)
- Volunteers
- 15 people
- Sponsor
- Dr. Behcet Uz Children's Hospital
Acute Respiratory Distress Syndrome, Severe Pneumonia
One Year Follow-ups of Patients Admitted to Spanish Intensive Care Units Due to COVID-19
The latest epidemiological data published from Chine reports that up to 30% of hospital-admitted patients required admission to intensive care units (ICU).
- Conditions
- Acute Respiratory Distress Syndrome, Severe Pneumonia, Respiratory Failure
- Trial name
- NCT04457505
- Where
- 31 sites in Spain
- Volunteers
- 8,500 people
- Sponsor
- Consorcio Centro de Investigación Biomédica en Red (CIBER)
Covid19, COVID-19 Pneumonia
imPulse™ Una Infrasound-to-ultrasound E-stethoscope
This study generates robust, uniform clinical data across emerging COVID-19 strains to train ML/AI algorithms of the Sponsor's imPulse™ Una infrasound-to-ultrasound e-stethoscope for digital diagnostic feature synthesis of…
- Conditions
- Covid19, COVID-19 Pneumonia, COVID-19 Respiratory Infection, COVID-19 Acute Respiratory Distress Syndrome
- Trial name
- NCT04941209
- Testing
- imPulse™ Una infrasound-to-ultrasound e-stethoscope, (PPA >95%) FDA EUA RT-PCR, HR-CT-scan
- Where
- 3 sites in Democratic Republic of the Congo, India and 1 more
- Volunteers
- 702 people
- Sponsor
- Level 42 AI, Inc.
Respiratory Distress Syndrome, Pediatric, Acute Lung Injury/Acute Respiratory Distress Syndrome (ARDS)
Continuous Infusion Versus Intermittent Boluses of Cisatracurium in the Early Management of Pediatric ARDS
The aim of this work is to compare continuous infusion vs on need intermittent boluses of Cisatracurium in the early management of pediatric acute respiratory distress syndrome
- Trial name
- NCT05153525
- Testing
- Intermittent boluses of Cisatracurium, Intravenous infusion of Cisatracurium for 24 hours
- Where
- 2 sites in Egypt
- Volunteers
- 60 people
- Sponsor
- Tanta University
Acute Respiratory Distress
The Epidemiology of Acute Respiratory Distress Among Children, A Retrospective Cross-Sectional Study
l Respiratory distress is still a major concern in pediatric medicine. l In this study we evaluated the symptoms and causes of respiratory distress among children in a tertiary hospital.
- Trial name
- NCT06578377
- Testing
- descriptive study
- Where
- Iran
- Volunteers
- 154 people
- Sponsor
- Mofid Children Hospital
Infant Respiratory Distress Syndrome, Acute Bronchiolitis
Continuous Regional Analysis Device for Neonate Lung
The purpose of the study is to assess whether Electrical Impedance Tomography (EIT) has the potential to optimize the ventilator therapy, validate the effectiveness, efficacy and safety of nursing and medical interventions…
- Conditions
- Infant Respiratory Distress Syndrome, Acute Bronchiolitis, Acute Respiratory Distress Syndrome
- Trial name
- CRADL (NCT02962505)
- Where
- 4 sites in Cyprus, Finland and 1 more
- Volunteers
- 200 people
- Sponsor
- University Hospital Schleswig-Holstein