Clinical trials: Abdominal Infection
Surgical Site Infection, Complication,Postoperative
Study to Analyze the Surgical Site Infections in a Group of Patients Who Were Randomly Applied a Negative Pressure Therapy Dressing Versus Conventional Dressing
Surgical site complications generate a series of consequences that prolong hospital stay, increase interventions and procedures, and consequently considerably increase healthcare costs.
- Conditions
- Surgical Site Infection, Complication,Postoperative, Surgical Wound Infection, Surgical Complication
- Trial name
- NCT05455801
- Testing
- negative preassure wound therapy
- Where
- Spain
- Volunteers
- 271 people
- Sponsor
- Hospital Universitario Central de Asturias
Laryngeal Masks, Pharyngitis
Postoperative Sore Throat in Children: Comparison Between Two Supraglottic Devices, Ambu® AuraOnce™ Laryngeal Mask Airway (LMA) and I-Gel®.
Sore throat is minor but well recognized complaint after receiving general anaesthesia. It is rated as 8th most undesirable outcome in postoperative period.It not only affects the patient's satisfaction but also can affect…
- Conditions
- Laryngeal Masks, Pharyngitis, Minors, Anesthesia
- Trial name
- NCT03140228
- Testing
- I-Gel, LMA
- Where
- Pakistan
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Aga Khan University
Acute Appendicitis, Appendicitis (Diagnosis)
Laparoscopic vs Open Appendectomy in Obese Patients
Acute appendicitis is one of the most common surgical emergencies globally. While surgical removal of the appendix (appendectomy) is the definitive treatment, the optimal surgical approach-laparoscopic versus open-remains widely…
- Conditions
- Acute Appendicitis, Appendicitis (Diagnosis), Obesity
- Trial name
- NCT07822503
- Testing
- Open Appendectomy, Laparoscopic Appendectomy
- Volunteers
- 166 people
- Sponsor
- University of Health Sciences Lahore
Bacterial Translocation, Surgical Site Infection
Plastic Wound Retractors and Bacterial Translocation in Abdominal Surgery
Hypothesis: Plastic wound retractors reduce passage of bacteria from the abdomen to the surgical incision site in abdominal surgery Currently, plastic wound retractors are used in abdominal surgery to facilitate access to the…
- Conditions
- Bacterial Translocation, Surgical Site Infection, Abdominal Surgery, Wound Infection
- Trial name
- NCT01007487
- Where
- 2 sites in Ireland
- Volunteers
- 250 people
- Sponsor
- St Vincent's University Hospital, Ireland
Acute Uncomplicated Appendicitis
Pilot Trial of Antibiotics Versus Surgery for Treating Acute Appendicitis
The major goal of the project is to demonstrate the feasibility of conducting a multi-center randomized clinical trial of antibiotic therapy versus appendectomy for the treatment of patients with acute uncomplicated appendicitis…
- Trial name
- NCT02447224
- Testing
- 1 gm IV ertapenem at enrollment, 1 gm IV ertapenem at Day 2 and oral metronidazole and cefdinir to complete 10 days, Appendectomy
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Olive View-UCLA Education & Research Institute
Appendicitis
Polymer Clips Versus Endoloops for Closure of the Appendiceal Stump During Emergency Laparoscopic Appendicectomy
The investigators propose a study to compare two methods of closing the stump of the appendix during an emergency excision of the appendix using a keyhole approach.
- Trial name
- PECAS (NCT02726152)
- Testing
- Polymer clips for closure of the appendiceal stump, Endoloops for closure of the appendiceal stump
- Where
- United Kingdom
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- National Health Service, United Kingdom
Complicated Intra Abdominal Infections
Antibiotic Safety (SCAMP)
The main purpose of this study is evaluate whether it is safe or not to use various combination of antibiotics (ampicillin, metronidazole, clindamycin, piperacillin-tazobactam, gentamicin) in treating infants with complicated…
- Trial name
- SCAMP (NCT01994993)
- Testing
- ampicillin and metronidazole and gentamicin, ampicillin and gentamicin and clindamycin, gentamicin and Piperacillin- tazobactam
- Where
- 50 sites in United States, Canada
- Volunteers
- 260 people
- Sponsor
- Michael Cohen-Wolkowiez
Other Acute Illnesses Presenting to the Hospital, Heart Failure
Evaluation of Implementation of a National Point-of-Care Ultrasound Training Program
This VA QUERI Partnered Evaluation Initiative will evaluate the impact of an immersive Point-of-care Ultrasound (POCUS) Training Course on provider skill acquisition and retention; the frequency of POCUS use by trained providers…
- Conditions
- Other Acute Illnesses Presenting to the Hospital, Heart Failure, Pneumonia, Deep Venous Thrombosis
- Trial name
- NCT03296280
- Where
- United States
- Volunteers
- 116 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Appendicitis
Diagnostic Accuracy of Serum Bilirubin in the Prediction of Perforated Appendicitis
Hyperbilirubinemia is reported to be a positive predictor in diagnosing perforated appendicitis. Therefore we analysed the diagnostic accuracy of serum bilirubin in discriminating between perforated and simple/no appendicitis.
- Trial name
- NCT01698099
- Where
- Germany
- Volunteers
- 500 people
- Sponsor
- University Hospital Tuebingen
Appendicitis
Open Versus Laparoscopic Appendectomy
The aim of this prospective randomized trial is to compare the feasibility of open with laparoscopic appendectomy in suspected acute appendicitis.
- Trial name
- NCT00908804
- Testing
- open appendectomy, laparoscopic appendectomy
- Where
- Finland
- Sponsor
- North Karelia Central Hospital
Covid19, Appendicitis
the Impact of COVID-19 Pandemic on the Incidence and Outcome of Complicated Appendicitis
During the COVID-19 pandemic, we noticed a rise in complicated appendicitis cases presenting to our medical center. We collected objective data on all patients admitted to the surgical department with appendicitis during February…
- Trial name
- NCT04786041
- Testing
- laparoscopic appendectomy
- Where
- Israel
- Volunteers
- 200 people
- Sponsor
- Meir Medical Center
Appendicitis, Surgery
Sugammadex vs Neostigmine Reversal in Pediatric Appendectomy
This study is designed as a randomized controlled trial with patients assigned to neuromuscular reversal with either sugammadex or neostigmine/glycopyrrolate reversal.
- Trial name
- NCT05256901
- Testing
- Sugammadex, Neostigmine/Glycopyrrolate
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- Emory University
Perforated Appendicitis
Surgical Site Infection in Perforated Appendicitis After Peritoneal Lavage With Super-oxidised Solution
This study is to evaluate the effectiveness of peritoneal lavage with super-oxidised solution in reducing surgical site infection after open surgery for perforated appendicitis.
- Trial name
- PLaSSo (NCT04512196)
- Testing
- Superoxidized Water, Normal Saline
- Where
- Malaysia
- Volunteers
- 102 people
- Sponsor
- Hospital Queen Elizabeth, Malaysia
Abdominal Hernia
Light vs Heavy Weighted Mesh Repair in Primary Abdominal Hernia in Terms of Surgical Site Infection
This study compares the incidence of surgical site infections (SSI) in patients undergoing abdominal hernia repair using either light or heavy-weighted polypropylene mesh.
- Trial name
- NCT06644612
- Testing
- Light Weight Mesh, Heavy Weight Mesh
- Where
- Pakistan
- Volunteers
- 106 people
- Sponsor
- Khyber Medical University Peshawar
Chronic Renal Failure
Open Label Trial to Establish the Equivalence Between ANDY-Disc® and Ultrabag® in Patients on CAPD.
Apart from haemodialysis, continuous ambulatory peritoneal dialysis (CAPD) is another effective therapy for end stage renal disease (ESRD).
- Trial name
- NCT00255619
- Testing
- Baxter's UltraBag® and FMC Andy·Disc®
- Where
- 6 sites in Malaysia
- Volunteers
- 264 people
- Sponsor
- Ministry of Health, Malaysia
Acute Appendicitis
Laparoscopic Assisted or Total Laparoscopic Appendectomy
Acute appendicitis (AA), is a common intra-abdominal surgical pathology with the overall incidence of approximately 7% and mortality of 0.2-0.8%.
- Trial name
- NCT02673528
- Testing
- Laparoscopic appendectomy
- Volunteers
- 451 people
- Sponsor
- Medical Park Gaziantep Hospital
Appendicitis
Pediatric Appendicitis Risk Calculator (pARC) in Children With Appendix Ultrasounds
Acute appendicitis (AA) is the most common condition requiring emergency surgery in children. At a network of institutions nationwide, a tool called the pediatric appendicitis risk calculator (pARC)1 is being studied to assess…
- Trial name
- NCT03522233
- Where
- 2 sites in United States
- Volunteers
- 800 people, healthy volunteers welcome
- Sponsor
- Children's Hospitals and Clinics of Minnesota
Enterobacteriaceae Infections, Bacteremia
Infections Caused by ESbL-Producing Enterobacteriaceae in Italy
To assess the molecular epidemiology, clinical impact, treatment outcome and risk factors for infections caused by Enterobacteriaceae producing ESBLs in Italy in a large multicenter observational survey. SPECIFIC OBJECTIVES 1.
- Conditions
- Enterobacteriaceae Infections, Bacteremia, Pneumonia, Skin Diseases
- Trial name
- NCT00404625
- Testing
- Risk factors for infections due to ESBL+ Enterobacteriaceae, Risk factors for inadequate initial antimicrobial therapy, Overall and 30-day mortality in bad first antibiotic therapy
- Where
- 6 sites in Italy
- Volunteers
- 813 people
- Sponsor
- University of Siena
Tuberculosis, Tuberculosis; Abdomen (Etiology)
Clinico-radiological Classification of Peritoneal Tuberculosis
Traditionally, peritoneal tuberculosis has been classified as wet-ascitic, dry-plastic type and fibrotic -fixed types. there is substantial overlap between these definitions and the clinical implication of the categorisation into…
- Conditions
- Tuberculosis, Tuberculosis; Abdomen (Etiology), Tuberculosis, Peritoneal
- Trial name
- NCT03927664
- Testing
- Radiological assessment
- Where
- 2 sites in India
- Volunteers
- 55 people
- Sponsor
- Post Graduate Institute of Medical Education and Research, Chandigarh
Soil-transmitted Helminthiasis, Schistosomiasis
Diagnosis of Neglected Tropical Diseases Among Patients With Persistent Digestive Disorders
NIDIAG is an international collaboration on integrated diagnosis-treatment platforms, funded by the European Commission (EC). NIDIAG aims to develop an improved, patient-centred system for delivering primary health care in…
- Conditions
- Soil-transmitted Helminthiasis, Schistosomiasis, Strongyloidiasis, Shigellosis
- Trial name
- NIDIAGDigest (NCT02105714)
- Testing
- Stool culturing for pathogenic bacteria, Kato-Katz technique, Baermann technique
- Where
- 7 sites in Côte d’Ivoire, Indonesia and 2 more
- Volunteers
- 2,800 people, healthy volunteers welcome
- Sponsor
- Swiss Tropical & Public Health Institute