Clinical trials: Abortion
Abortion Early
Very Early Medical Abortion
The research question begin addressed by this study is "Is Very Early Medical Abortion (VEMA - before a pregnancy is visible on ultrasound scan) as effective as medical abortion when performed later and an intrauterine pregnancy…
- Trial name
- VEMASCOT (NCT03989869)
- Testing
- Immediate treatment
- Where
- United Kingdom
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- NHS Lothian
Infections, Papillomavirus
Post-marketing Safety Study to Assess the Risk of Spontaneous Abortions in Women Exposed to Cervarix Residing in UK
This study will assess the risk of spontaneous abortion during weeks 1-23 and weeks 1-19 of gestation, respectively, and other pregnancy outcomes, in an exposed cohort, i.e.
- Trial name
- NCT01905462
- Testing
- Data Collection, Cervarix
- Where
- United Kingdom
- Volunteers
- 1,046 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Abortion in First Trimester, Abortion Early
A Patient Decision Aid for Method of Early Abortion: a Randomized Control Trial
Introduction: There are two options for women seeking early pregnancy termination in Canada; either surgical or medication abortion.
- Conditions
- Abortion in First Trimester, Abortion Early, Decision Aid, Clinical Decision-making
- Trial name
- NCT05182008
- Testing
- Decision aid, Usual care
- Where
- Canada
- Volunteers
- 365 people, healthy volunteers welcome
- Sponsor
- Nova Scotia Health Authority
Medical Abortion
The Acceptability and Feasibility of an Alternative to Routine Follow-up Visit After Medical Abortion in Vietnam
This trial will compare the efficacy and acceptability of post-medical abortion follow-up by assigning women to either 1) alternative follow-up via routine semi-quantitative pregnancy test and a self-administered follow-up…
- Trial name
- NCT01150422
- Testing
- Alternative follow-up
- Where
- 4 sites in Vietnam
- Volunteers
- 1,500 people, healthy volunteers welcome
- Sponsor
- Gynuity Health Projects
Medical Abortion
Outpatient Medical Abortion With Mifepristone and Misoprostol Through 77 Days of Gestation
To demonstrate non-inferiority of the efficacy of 200 mg mifepristone followed in 24 to 48 hours by 800 µg buccal misoprostol in outpatient medical abortion services among women 71-77 days' compared to women 64-70 days' LMP.
- Trial name
- XXGA (NCT02314754)
- Testing
- Mifepristone followed by misoprostol 24-48 hours later
- Where
- 8 sites in United States, Azerbaijan and 3 more
- Volunteers
- 719 people, healthy volunteers welcome
- Sponsor
- Gynuity Health Projects
Retained Products of Conception Post Abortion
Oral Contraceptive Pills Versus Expectant Management for Retained Pregnancy Products
We speculate that the use of combined oral contraceptives may be a possible solution to promote the management of retained pregnancy products versus expectant management.
- Trial name
- NCT03230825
- Testing
- Oral contraceptive, Expectant management
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Meir Medical Center
Pregnancy
Evaluation of Telemedicine Medical Abortion Service in Ecuador
This research seeks to demonstrate that a telemedicine model for the provision of legal abortion services in Ecuador is safe, feasible and acceptable to users requesting a medication abortion and who are less than 12 weeks…
- Trial name
- NCT06270056
- Testing
- Misoprostol
- Where
- 3 sites in Ecuador
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Gynuity Health Projects
Abortion, Induced
Mifepristone Plus Misoprostol Versus Misoprostol Alone for 2nd Trimester Abortion (14 - 21 Weeks Last Menstrual Period (LMP))
The primary goal of this study is to determine the clinical advantage of pre-treatment with mifepristone in second trimester misoprostol induction abortion.
- Trial name
- NCT00969982
- Testing
- mifepristone+misoprostol
- Where
- 2 sites in Moldova, Tunisia
- Volunteers
- 238 people, healthy volunteers welcome
- Sponsor
- Gynuity Health Projects
Contraception
RCT: Can a Single Counseling Phone Call Improve Contraception After an Abortion?
Hypothesis: Use of an effective contraceptive six weeks after abortion will be higher in the treatment group than in the control group.
- Trial name
- PPR (NCT01199952)
- Testing
- Treatment group: receives counseling phone call intervention
- Where
- United States
- Volunteers
- 207 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Contraception
Study of Immediate Start of Progestin Contraceptives in Medical Abortion
This study will compare immediate to post-abortion start of two progestin-based contraceptives (DMPA and etonorgestrel implants) among women having first trimester medical abortion who wish to use that method for post-abortion…
- Trial name
- Quickstart (NCT01902485)
- Testing
- Timing of Contraceptive Initiation in Medical Abortion
- Where
- 8 sites in United States, Mexico
- Volunteers
- 937 people, healthy volunteers welcome
- Sponsor
- Gynuity Health Projects
Medical Abortion
Self-Assessment of Medical Abortion Outcome Using Serial Multi-level Pregnancy Tests
This study aims to investigate the effectiveness and acceptability of the multi-level pregnancy test for self-assessment of abortion outcomes, without a routine provider contact.
- Trial name
- NCT02570204
- Testing
- Self-assessment
- Where
- 3 sites in United States
- Volunteers
- 343 people, healthy volunteers welcome
- Sponsor
- Gynuity Health Projects
Missed Miscarriage
Mifepristone and Misoprostol Versus Misoprostol Alone in the Medical Management of Missed Miscarriage
Miscarriage is the most common complication of pregnancy. As many as 15-25% of pregnancies end in miscarriage, and the number of miscarriages in England is estimated to be approximately 125,000 per year.
- Trial name
- MifeMiso (NCT03065660)
- Testing
- Mifepristone, Oral, 200 Mg
- Where
- 28 sites in United Kingdom
- Volunteers
- 711 people, healthy volunteers welcome
- Sponsor
- University of Birmingham
Recurrent Miscarriages
Maternal KIR and Fetal HLA-C Genes in Recurrent Miscarriages
For implantation of developing conceptus, placental cells need to invade mother's uterus to access maternal blood supply in a control manner.
- Trial name
- NCT00180804
- Where
- United Kingdom
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Imperial College London
Fibroid, Miscarriage in First Trimester
Fibroids and the Risk of Miscarriage: a Prospective Observational Study in an Early Pregnancy Population
The aim of this observational study is to whether fibroids increase the risk of miscarriage in women in our early pregnancy population.
- Conditions
- Fibroid, Miscarriage in First Trimester, Miscarriage in Second Trimester
- Trial name
- FiRM (NCT06986616)
- Where
- United Kingdom
- Volunteers
- 436 people, healthy volunteers welcome
- Sponsor
- King's College Hospital NHS Trust
Post Abortion Care
Contraceptive Counseling Following an Abortion
The purpose of this study is to determine whether contraceptive counseling is effective on acceptance and use of methods in women following an abortion.
- Trial name
- APA (NCT00756314)
- Testing
- Personalized contraceptive counseling
- Where
- Brazil
- Volunteers
- 246 people, healthy volunteers welcome
- Sponsor
- Instituto Materno Infantil Prof. Fernando Figueira
Reproductive Health
Improving Person Centered Care for Post Abortion Patients in Kenya
The purpose of this study is to understand the effect of a phone based post-abortion intervention on the experience of post-abortion care.
- Trial name
- SPARQ_PACK (NCT04206514)
- Testing
- Person Centered Care - Post Abortion Support
- Where
- Kenya
- Volunteers
- 371 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Birth Weight, Miscarriage
Micronutrient Supplementation Before and During 1st Pregnancy to Improve Birth Outcomes (JiVitA-5)
The purpose of this cluster-randomized trial is to evaluate the efficacy of daily, multiple micronutrient (MM) supplement versus identical placebo use among nulligravid, recently married women, starting preconceptionally through…
- Conditions
- Birth Weight, Miscarriage, Small-for-gestational Age, Preterm Birth
- Trial name
- JiVitA-5 (NCT03921177)
- Testing
- Multiple micronutrient supplement
- Where
- Bangladesh
- Volunteers
- 9,859 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins Bloomberg School of Public Health
Pregnancy; Habitual Aborter, Weeks of Gestation 37 or More
Accuracy and Reliability of Fetal Heart Rate and Uterine Contraction Monitoring Method
Clinical Investigation Protocol for a study designed to determine the equivalence of the Monica AN24 monitor to Philips 50XM for fetal heart rate (FHR) and uterine contraction (UC) monitoring during labor.
- Trial name
- NCT01280357
- Testing
- Monica AN24 (K101081), Philips 50XM
- Where
- 2 sites in United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Monica Healthcare Ltd
Legally Induced Abortion Without Mention of Complication
A Comparison of Sublingual and Buccal Misoprostol Regimens After Mifepristone for Mid-trimester Abortion
The primary goal of this study is to directly compare repeat doses of sublingual and buccal routes of 400 mcg misoprostol following mifepristone for second trimester abortion in order to determine if sublingual route confers an…
- Trial name
- NCT02708446
- Testing
- Mifepristone, Buccal misoprostol, Sublingual misoprostol
- Where
- 4 sites in Armenia, Nepal and 2 more
- Volunteers
- 320 people, healthy volunteers welcome
- Sponsor
- Gynuity Health Projects
Medical Abortion
Simplifying Menstrual Regulation (MR): Post Abortion Care in Pakistan
This study is an additional component of protocol 6005, titled Simplifying Menstrual Regulation (MR): Exploring the role of at-home semi-quantitative pregnancy tests for follow-up to menstrual regulation service provision in…
- Trial name
- NCT02343913
- Testing
- PAC checklist
- Where
- 15 sites in Pakistan
- Volunteers
- 329 people, healthy volunteers welcome
- Sponsor
- Gynuity Health Projects