Clinical trials: Absence
Epilepsy
Open-Label Extension Study to Assess the Safety and Seizure Frequency Associated With Lacosamide for Primary Generalized Tonic-Clonic Seizures in Subjects With Epilepsy
The purpose is to obtain data on the safety and seizure frequency associated with long-term oral Lacosamide for uncontrolled primary generalized tonic-clonic (PGTC) seizures in subjects with idiopathic generalized Epilepsy.
- Trial name
- NCT01118962
- Testing
- Lacosamide
- Where
- 19 sites in United States
- Volunteers
- 39 people
- Sponsor
- UCB BIOSCIENCES, Inc.
Caries; Dentin, Dental Restoration Failure of Marginal Integrity
Absence of Liner Following the Selective Caries Removal (ALFSCaRe)
This randomized, multi-centric, controlled clinical trial will assess the effectiveness of a simplified restorative protocol used after the selective carious tissue removal in posterior teeth presenting deep carious lesions.
- Trial name
- (ALFSCaRe) (NCT03933176)
- Testing
- Restoration of carious lesions
- Where
- Brazil
- Volunteers
- healthy volunteers welcome
- Sponsor
- Universidade Federal de Sergipe
Asenteeism
Classroom Air Purifiers for Reducing School Absence
Background Respiratory infections like influenza and SARS-CoV-2 pose significant global health risks due to their high transmissibility and severity.
- Trial name
- NCT07119333
- Testing
- Air purifiers
- Where
- Norway
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Norwegian Institute of Public Health
Obesity
Learning Theory to Improve Obesity Treatment
The purpose of this study is to optimize an obesity treatment program targeting overweight 8-12 year old children using "Cue Exposure Training".
- Trial name
- iROC (NCT01708785)
- Testing
- Single food Cue Exposure Treatment, Multiple food Cue Exposure Treatment, Partial Reinforcement - Enhanced Cue Exposure Treatment
- Where
- United States
- Volunteers
- 230 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
Mental Disorders
Application of Psychiatric Knowledge in the Rehabilitation Process in Return to Work.
The hypothesis was that education of rehabilitation officers who were responsible for rehabilitation back to work for sick-listed individuals in screening for mental disorders and psychiatric topics would increase the rate of…
- Trial name
- PKRW (NCT01989767)
- Testing
- control Rehabilitation as usual, education
- Where
- Denmark
- Volunteers
- 317 people
- Sponsor
- Hans Joergen Soegaard
Upper Respiratory Tract Infections
The Association of Hand Hygiene Practice on Primary Schoolgirls Absence Due to URIs in Riyadh City, 2017-2018.
Research Problem: Upper respiratory infections (URIs) are a common reason for absence from schools as it is estimated that children get six to eight episodes every year.
- Trial name
- NCT03535064
- Testing
- Hand Hygiene Workshop
- Where
- Saudi Arabia
- Volunteers
- 496 people
- Sponsor
- Abrar Alzaher
Absence Epilepsy, Epilepsy, Absence
Longitudinal Early Epilepsy Study
This longitudinal study will focus on the cognitive and brain development of children with absence epilepsy. In addition, the investigators aim to identify prognostic factors for cognitive deterioration and/or poor seizure…
- Trial name
- LEES (NCT02954107)
- Testing
- MRI, 24h-EEG + video, Neuropsychological tests
- Where
- 2 sites in Netherlands
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center
Prostate Cancer
Evaluation of a Blood Biomarker to Try and Distinguish Between the Presence or Absence of Aggressive Prostate Cancer
A Laboratory Study to Evaluate Urine and Blood Biomarkers That Can Distinguish Between the Presence or Absence of Aggressive Prostate Cancer
- Trial name
- NCT03256630
- Where
- United States
- Volunteers
- 128 people
- Sponsor
- Genomic Health®, Inc.
Obesity, Overweight
Family Based Treatment for Weight Loss With Breakfast Prescription
The purpose of this study is to evaluate whether a behavioral weight loss group in conjunction with a prescribed breakfast can help children between 8 and 12 years of age change their behaviors to help them lose weight and become…
- Conditions
- Obesity, Overweight, Overeating, Weight
- Trial name
- FAB (NCT02467036)
- Testing
- Family Based Behavioral Treatment
- Where
- United States
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
Study the Efficacy of Epidiolex for Typical Absence Seizures
Epidiolex in Typical Absence Seizures
This is a Pilot study, open-label study consisting of a screening period of up to 4 weeks, a 4-week dose-titration treatment period to dose of up to 20 mg/kg/day BID of CBD (Epidiolex), and a 30 day safety follow-up period…
- Trial name
- NCT04899050
- Testing
- Cannabidiol (Epidiolex)
- Where
- United States
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- University of South Florida
Childhood Absence Epilepsy, Epilepsy
Search for Genes Influencing Childhood Absence Epilepsy (CAE) Study
The purpose of our study is to identify gene(s) involved in the cause of childhood absence epilepsy (CAE).
- Conditions
- Childhood Absence Epilepsy, Epilepsy, Seizures
- Trial name
- NCT00041951
- Where
- United States
- Volunteers
- 185 people, healthy volunteers welcome
- Sponsor
- Icahn School of Medicine at Mount Sinai
Amenorrhea, Premature Ovarian Failure
GnRH Analogue for Ovarian Function Preservation in Hematopoietic Stem Cell Transplantation Patients
Primary Objectives: To determine the effectiveness of the 3-month depot leuprolide in inducing and maintaining secondary amenorrhea in patients undergo hematopoietic stem cell transplantation.
- Conditions
- Amenorrhea, Premature Ovarian Failure, Ovarian Function Insufficiency
- Trial name
- NCT00429494
- Testing
- Leuprolide Acetate, Questionnaire, Hematopoietic Stem Cell Transplantation
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- M.D. Anderson Cancer Center
Pregnancy, Sickness Absence
Active Pregnancy Policy at Work. Greater Wellbeing and Lower Sickness Absence
In a cluster randomized design it will be investigated whether teaching local leaders how to implement active pregnancy policy results in less sickness absence among their pregnant employees.
- Conditions
- Pregnancy, Sickness Absence, Occupational Exposure
- Trial name
- AGp (NCT03002987)
- Testing
- Active Pregnancy policy
- Where
- Denmark
- Volunteers
- 866 people, healthy volunteers welcome
- Sponsor
- Bispebjerg Hospital
Clubfoot
Rate Of Residual Clubfoot Deformity With Correlation To Absence Of Peroneus Tertius Muscle
Rate Of Residual Clubfoot Deformity With Correlation To Absence Of Peroneus Tertius Muscle , A Prospective Study.
- Trial name
- NCT03749265
- Testing
- Ultrasound test
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- HaEmek Medical Center, Israel
Prostate Cancer
Choline-PET for Evaluating the Incidence of Nodal Metastases Among Newly Diagnosed Patients of Prostate Cancer
Nodal involvement among patients with prostate cancer is known to be a poor prognostic factor. Traditionally, the presence or absence of nodal disease in patients with prostate cancer is ascertained with the use of anatomical…
- Trial name
- ChoPEN (NCT01769950)
- Testing
- Choline-PET
- Where
- India
- Volunteers
- 120 people
- Sponsor
- Bangalore Institute of Oncology
Absence Seizures, Absence Epilepsy
ECV - Epihunter Clinical Validation
The goal of this prospective study is to validate a wearable EEG seizure detection solution compared to video EEG. Subjects that undergo a clinical video EEG are asked to additionally wear a wearable EEG headband for up to 2…
- Trial name
- ECV (NCT04615442)
- Testing
- Epihunter
- Where
- 4 sites in United States, Belgium and 2 more
- Volunteers
- 102 people
- Sponsor
- Epihunter NV
Acute Myeloid Leukemia (AML)
Luveltamab Tazevibulin (STRO-002) in Infants and Children < 12 Years of Age With Relapsed/Refractory CBFA2T3::GLIS2 AML
This trial will evaluate whether luveltamab tazevibulin is well tolerated and active against a rare form of AML carrying a particular genetic abnormality called CBFA2T3::GLIS2 that arises in infants and children.
- Trial name
- NCT06679582
- Testing
- Luveltamab tazevibulin
- Where
- 36 sites in United States, Austria and 7 more
- Volunteers
- 1 people
- Sponsor
- Sutro Biopharma, Inc.
Autism Spectrum Disorder, Autism Spectrum Disorder (ASD)
Intranasal Insulin for Autism Spectrum Disorder in Children and Young Adults Aged 4 to 21 Years
This observational study evaluates the real-world use of intranasal insulin in children and young adults with autism spectrum disorder (ASD) utilizing the ViaNase™ device developed by Kurve Therapeutics.
- Conditions
- Autism Spectrum Disorder, Autism Spectrum Disorder (ASD), Autism Spectrum Disorder High-Functioning, Autism Spectrum Disorder With Absence of Functional Language
- Trial name
- IN-INS-AUT (NCT07521371)
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Healing Hope International
Childhood Absence Epilepsy, Juvenile Absence Epilepsy
Flunarizine for Treatment Resistant Absence Epilepsy
This is an open-label, single-centre study to evaluate the clinical efficacy, safety and tolerability of Flunarizine administered as adjunctive treatment in participants diagnosed with treatment resistant absence epilepsy.
- Conditions
- Childhood Absence Epilepsy, Juvenile Absence Epilepsy, Juvenile Myoclonic Epilepsy
- Trial name
- NCT06153186
- Testing
- Flunarizine Hydrochloride
- Where
- Canada
- Volunteers
- 9 people
- Sponsor
- University of British Columbia
Childhood Absence Epilepsy, Absence Seizures
Assessing Comorbidities in Epilepsy Using Eye Movement Recordings
This study wants to make it easier to find kids with a type of epilepsy called childhood absence epilepsy (CAE) who might have problems with ongoing seizures and thinking.
- Conditions
- Childhood Absence Epilepsy, Absence Seizures, Epilepsy Comorbidities
- Trial name
- ACER (NCT06310772)
- Where
- 2 sites in United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Eysz, Inc.