Clinical trials: Absorption
Environmental Enteric Dysfunction, Zinc Deficiency
Effects of EED on Zn Absorption and Retention in Children From a Standard Dose
The overall objective is to determine the impact of EED on zinc absorption and homeostasis, and its impact on the absorptive capacity of vitamin A absorption of young children (18-24 months of age) in an austere setting with high…
- Conditions
- Environmental Enteric Dysfunction, Zinc Deficiency, Vitamin A Deficiency
- Trial name
- ZEED1 (NCT02760095)
- Testing
- 3 mg zinc sulfate supplement, 0.5 mg of 13C10-retinyl-acetate
- Where
- 2 sites in United States, Bangladesh
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Asthma
Genotype Stratified Pharmacokinetic Study of Montelukast
Leukotriene receptor antagonists (LTRAs) are frequently prescribed to reduce the symptoms associated with asthma. Singulair (montelukast), manufactured by Merck, is a popular LTRA, however its effectiveness varies greatly between…
- Trial name
- GSPOM (NCT01086527)
- Testing
- 10 mg tablet of montelukast (Singulair)
- Where
- United States
- Volunteers
- 2 people, healthy volunteers welcome
- Sponsor
- Nemours Children's Clinic
Environmental Enteric Dysfunction, Zinc Deficiency
Effects of EED on Zn Absorption and Retention in Children From a MNP
The overall objective is to determine the impact of EED on total daily zinc absorption of young Bangladeshi children (18-24 months of age) in an austere setting with high rates of diarrhea, stunting, and micro-nutrient…
- Trial name
- ZEED2 (NCT02758444)
- Testing
- Micronutrient Powder (MNP) + 15 mg Zn, MNP + 10 mg Zn, MNP + 5 mg Zn
- Where
- 2 sites in United States, Bangladesh
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Vitamin D Deficiency
Treatment of Vitamin D Insufficiency
The purpose of this study is to answer the following questions: Does vitamin D increase calcium absorption, bone mass and muscle mass and function in women past menopause who have mildly low vitamin D levels? Do these benefits…
- Trial name
- NCT00933244
- Testing
- High Dose Vitamin D3, Low Dose Vitamin D3
- Where
- United States
- Volunteers
- 230 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
Osteoporosis
Dose Effects of SCF on Calcium Metabolism and GI Microflora in Adolescents
Soluble corn fiber (SCF) has been shown to enhance calcium utilization and bone properties in rats and in adolescent boys and girls.
- Trial name
- NCT01660503
- Testing
- 0 grams SCF, 10 grams SCF, 20 grams SCF
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Purdue University
Osteoporosis
Fructooligosaccharide and Calcium Absorption in Adolescent Girls
Fructooligosaccharides (FOS) are believed to have positive effects on calcium absorption and bone accrual during growth. This study aims to see whether the addition of fiber in the form of FOS to a calcium-containing beverage…
- Trial name
- NCT01005927
- Testing
- Fructooligosaccharide
- Where
- United States
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Purdue University
Anemia, Iron-deficiency
The Effect of Human Milk Oligosaccharides and Galacto-oligosaccharides on Iron Absorption in Kenyan Infants
Effective and safe strategies to deliver iron to infants and young children in Sub-Saharan Africa are urgently needed. One potential strategy to improve safety of iron fortification is to limit the total amount of unabsorbed iron…
- Trial name
- FeHMOGOS (NCT04163406)
- Testing
- ferrous fumarate, ferrous fumarate + GOS, ferrous fumarate + HMOs
- Where
- Kenya
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- Swiss Federal Institute of Technology
Mineral Absorption
Evaluation of Calcium, Vitamin D, Magnesium, and Zinc Absorption in Children
The goal of our research is to provide data to enhance the development of nutritional guidelines, especially as related to mineral nutrition, in children.
- Trial name
- NCT00868738
- Testing
- Vitamin D
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Baylor College of Medicine
Healthy
Evaluation of Fe Absorption From Iron Salt in Milk
The primary objective was: to compare iron absorption in apparently healthy children aged 3-6y from an instant full cream milk drink fortified with ferric pyrophosphate or ferric ammonium phosphate relative to ferrous sulfate as…
- Trial name
- NCT05642689
- Testing
- Iron fortified milk with iron salt labelled with 58Fe and 57Fe
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Société des Produits Nestlé (SPN)
Healthy Participants, Non-anemic Children
Ferrous Fumarate and Ferric Pyrophosphate as Food Fortificants in Developing Countries
Iron fortification of foods is usually considered the most cost-effective approach to prevent iron deficiency. However, iron is the most difficult mineral to add to foods.
- Conditions
- Healthy Participants, Non-anemic Children, Helicobacter Pylori Infection
- Trial name
- NCT00867867
- Testing
- Ferrous fumarate, Ferric pyrophosphate
- Volunteers
- 235 people, healthy volunteers welcome
- Sponsor
- International Centre for Diarrhoeal Disease Research, Bangladesh
Pneumoperitoneum
CO2 Absorption During Laparoscopy
CO2 absorption from the pneumoperitoneum increases over time during laparoscopic procedures. Adding 4% of oxygen to the carbon dioxide was shown in rabbits to decrease CO2 resorbtion through prevention of mesothelial hypoxia.
- Trial name
- NCT01340989
- Testing
- alteration of the insufflation gas, full conditioning, standard pneumoperitoneum
- Where
- Belgium
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University Hospital, Gasthuisberg
Iron-deficiency, Iron Deficiency Anemia
Iron Absorption and Exercise
Iron is a nutritionally essential mineral required for optimal physical and cognitive performance. Endurance exercise often leads to declines in iron status; however, the reason for the decline is not known.
- Trial name
- NCT04079322
- Testing
- Meal
- Where
- United States
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- Florida State University
Iron Deficiency, Anemia
The Efficacy of a Local Vitamin-C Rich Fruit (Guava) in Improving Iron Absorption From Mungbean Based Meals and Its Effect on Iron Status of Rural Indian Children (6-10 Years)
Iron deficiency is estimated to affect about one fifth of the world's population, and women and children are among the most severely affected.
- Trial name
- MUGUST_2 (NCT01191463)
- Testing
- Mung Bean Meal, Guava
- Where
- India
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Wageningen University
Intestinal Absorption
Comparative A1 vs A2 Formula and Breast Feeding on Alimentation and Gastrointestinal Digestion for the Infant
This pilot study primarily aimed to compare effects of breast feeding, A1 versus A2®cow milk based formula on alimentation and gastrointestinal digestion.
- Trial name
- NCT03081936
- Testing
- Oral consumption of Nutricia Aptamil Stage 1 formula, Oral consumption of a2® Platinum Stage 1 formula, Oral consumption of breast milk
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- a2 Milk Company Ltd.
Iron Absorption
Iron Absorption From an Iron-fortified Follow-up Formula With Added Synbiotic or Human Milk Oligosaccharides
The co-primary objectives of this study are: 1) to investigate the effect adding a synbiotic (combination of a pre-and probiotic) to iron-fortified follow-up formula (FUF) on iron bioavailability, and 2) to investigate the effect…
- Trial name
- NCT04774016
- Testing
- Test formula A without added pre- and pro-biotic, Test formula B with synbiotic, Test formula C with HMOs
- Where
- Thailand
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- Société des Produits Nestlé (SPN)
Malnutrition
Exchangeable Zinc Pool Size and Zn Absorption From Sprinkles and Traditional Foods in Pakistani Infants /Toddlers
The broad objective is to improve zinc status in older infants and young children who are at risk of zinc deficiency because of combination of inadequate dietary zinc intake and high rates of diarrhea.
- Trial name
- NCT01541696
- Where
- Pakistan
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Aga Khan University
Bronchiolitis, Bronchiolitis, Viral
Nasal and Bronchial Absorption Sampling in RSV Bronchiolitis
This study will compare the novel methods of NS and BS with the standard technique of nasophayngeal aspiration (NPA) and routine ETT suction.
- Conditions
- Bronchiolitis, Bronchiolitis, Viral, RSV Infection, Respiratory Failure
- Trial name
- RSV-SAM (NCT03062917)
- Testing
- Nasal and Bronchial Sampling
- Where
- United Kingdom
- Volunteers
- 152 people, healthy volunteers welcome
- Sponsor
- Imperial College Healthcare NHS Trust
Mineral Absorption in the Urine
Evaluation of Mineral Absorption in Infants Fed Infant Formula
This clinical trial will help determine if prebiotics can increase mineral absorption in babies
- Trial name
- NCT01177917
- Testing
- Infant Formula
- Where
- 5 sites in United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Mead Johnson Nutrition
Infant Allergy, Infant Gut Health
Study on the Impact of Different Feeding Methods on Allergy Prevention and Digestive Absorption in Infants and Young Children
Based on a real-world research paradigm, this study aims to evaluate the performance of infants fed via different methods-specifically goat milk formula, control formula, and breastfeeding-regarding allergy prevention and protein…
- Conditions
- Infant Allergy, Infant Gut Health, Infant Respiratory Diseases, Infant Feeding Scale
- Trial name
- NCT07886437
- Testing
- Observation, biological sample collection: stool
- Where
- China
- Volunteers
- 696 people, healthy volunteers welcome
- Sponsor
- Tsinghua University
Sleep, Inadequate, Energy Deficit
The Effects of Repeated Operational Stress and Limited Recovery on Resilience Capacity
This longitudinal study will examine the effects of repeated bouts of operational stress and limited recovery on integrated MPS, whole-body protein balance, iron absorption, and aerobic performance.
- Conditions
- Sleep, Inadequate, Energy Deficit, Iron Absorption, High Physical Activity
- Trial name
- REP DEF (NCT06784544)
- Testing
- Operational Stressors
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- United States Army Research Institute of Environmental Medicine