Clinical trials: Abuse, Drug
Substance Use, Sexual Risk Behaviors
Targeting HIV Risk Behaviors in Juvenile Drug Court-Involved Youth
This study is designed to gain knowledge about effective interventions for reducing HIV risk in a high risk population. A new Risk Reduction Therapy for Adolescents (RRTA) will be compared to usual services received by youth in…
- Trial name
- NCT01511380
- Testing
- Risk Reduction Therapy for Adolescents, Usual services
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- Medical University of South Carolina
Substance Abuse
Preventing Drug Abuse Among Sexual Minority Youth
The planned randomized clinical trial will longitudinally test a tailored, web-based drug abuse prevention program with a nationwide sample of 15- to 17-year-old sexual minority youth (youth who identify as gay, lesbian…
- Trial name
- NCT03954535
- Testing
- Free2b
- Where
- United States
- Volunteers
- 1,216 people, healthy volunteers welcome
- Sponsor
- Columbia University
Recreational Drug Use, Sexual Violence
Evaluation of Teen Connection Project for Trans and Gender Minority Youth
The purpose of this project is to develop and evaluate an online mentoring and skill-building program for transgender and/or gender minority youth (TGMY) ages 14 to 18, the Teen Connection Project (TCP).
- Conditions
- Recreational Drug Use, Sexual Violence, Victimisation, Depressive Symptoms
- Trial name
- TCP (NCT06587139)
- Testing
- Teen Connection Project (TCP)
- Where
- United States
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Buprenorphine, Naloxone
Observational Study of Misuse of High Dose Buprenorphine (Subutex® or Generic) in Opiate-Addicted Patients in France (Study P05186AM1)(COMPLETED)
The purpose of this study is to assess the risks of abuse, misuse and adverse events related to high dose buprenorphine. Approximately 1250 patients taking Subutex (Schering-Plough) or its Buprenorphine High Dose (BHD) generic…
- Conditions
- Buprenorphine, Naloxone, Opiate-related Disorders, Opiate Dependence
- Trial name
- OPUS R (NCT00723697)
- Testing
- buprenorphine
- Volunteers
- 1,307 people
- Sponsor
- Indivior Inc.
Suicidal Ideation, Social Behavior
Massive Mental Health Screening Using Smartphones in 24 Pre-graduate Education Centers in Mexico City: TEDUCA Survey Protocol
The objective of this study is to make a massive suicide risk and social behavior assessment in 24 pre-graduate education centers in Mexico City (approximately 30,000 students aged between 15 and 22 years), taking also into…
- Conditions
- Suicidal Ideation, Social Behavior, Depression, Depressive Disorder
- Trial name
- TEDUCA (NCT04067076)
- Testing
- Self-administered evaluation questionnaire
- Where
- Mexico
- Volunteers
- 30,000 people
- Sponsor
- Instituto de Investigación Sanitaria de la Fundación Jiménez Díaz
Risk Behavior, Substance Abuse
Juvenile Offender HIV Prevention and Drug Abuse Services
This study will determine the clinical effectiveness, moderators and mechanisms of change, and economic impact of an integrative, family-based intervention that concurrently targets change in HIV/Sexually Transmitted Disease…
- Conditions
- Risk Behavior, Substance Abuse, Delinquency
- Trial name
- Day Treatment (NCT01922297)
- Testing
- Day Treatment MDFT-HIV, Day Treatment SAU
- Where
- United States
- Volunteers
- 121 people, healthy volunteers welcome
- Sponsor
- University of Miami
Substance-Related Disorders
Medical Office Intervention for Adolescent Drug Use
The goal of this study is to assess the efficacy of a new intervention based on motivational enhancement therapy among adolescents with a history of substance use.
- Trial name
- NCT00229983
- Testing
- Motivational Enhancement Therapy
- Where
- United States
- Volunteers
- 170 people
- Sponsor
- Boston Children's Hospital
HIV-infection/Aids
Healthy Teen Girls: HIV Risk Reduction
This project assesses the efficacy of an HIV prevention program with adolescent females incarcerated in the Mississippi training school for girls.
- Trial name
- NCT00787696
- Testing
- Cognitive-behavioral HIV/STD risk reduction
- Where
- United States
- Volunteers
- 333 people, healthy volunteers welcome
- Sponsor
- Mississippi State University
Opioid Abuse, Opioid Addiction
The Discriminative Effects of Tramadol in Humans
This research is part of a set of studies whose purpose is to test whether tramadol can be used for the treatment of opioid addiction. Tramadol is already available in the United States as a pain medicine marketed as Ultram.
- Conditions
- Opioid Abuse, Opioid Addiction, Stimulant Abuse, Stimulant Addiction
- Trial name
- NCT00499746
- Testing
- tramadol, Hydromorphone, Methylphenidate
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- National Institute on Drug Abuse (NIDA)
Substance-Related Disorders, Drug Addiction
Home-Based Program to Help Parents of Drug Abusing Adolescents
This project is aimed at parents with a teenager who is already starting to use drugs. The study will test a new, innovative version of a brief intervention.
- Conditions
- Substance-Related Disorders, Drug Addiction, Substance Abuse
- Trial name
- NCT01591239
- Testing
- Home-Based Intervention, Educational Group
- Where
- United States
- Volunteers
- 286 people, healthy volunteers welcome
- Sponsor
- Treatment Research Institute
Doping in Sport, Performance Enhancing Product Use
Videogame for the Prevention of Doping and Supplement Abuse in Teenage Athletes
The purpose of this research is to test the effectiveness of an interactive doping education videogame among student athletes. Specifically, the game will teach athletes aged 13-16 years about the risks of doping and will foster…
- Trial name
- NCT04203992
- Testing
- Videogame, Control
- Volunteers
- 284 people, healthy volunteers welcome
- Sponsor
- McGill University
Adolescent Behavior
Drug Use Prevention Among Girls Through a Mother-Daughter Intervention
This study will develop and test drug use prevention strategies for low-income, minority girls. Gender-specific substance use rates, risk and protective factors, and health outcomes highlight the need for interventions aimed at…
- Trial name
- NCT00310258
- Testing
- Drug use prevention intervention
- Where
- United States
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- National Institute on Drug Abuse (NIDA)
Opioid-related Disorders, Opioid Addiction
ER/LA Opioid Surveillance for Emergency Department Visits and Hospitalizations for Overdose and Poisoning
Study to evaluate the impact of the ER/LA opioid REMS program on the incidence of Emergency Department visits and hospitalizations for overdose/poisoning and death among patients prescribed ER/LA opioid analgesics.
- Conditions
- Opioid-related Disorders, Opioid Addiction, Narcotic Abuse, Drug Abuse
- Trial name
- NCT02866266
- Testing
- Retrospective database review
- Volunteers
- 183,452 people
- Sponsor
- ER/LA Opioid REMS Program Companies (RPC)
Substance Use Disorders, Adolescent Behavior
Addiction in Adolescence - Pathomechanisms and Treatment Evaluation
This study aims to investigate the sociodemographic background as well as psychiatric comorbidities of adolescent substance users with substance use disorders.
- Trial name
- MATRIX-A (NCT03444974)
- Testing
- adapted treatment according to the MATRIX-A therapy
- Where
- Germany
- Volunteers
- 450 people, healthy volunteers welcome
- Sponsor
- Technische Universität Dresden
Neonatal Abstinence Syndrome
Efficacy and Outcomes of a Non-Pharmacological Intervention for Neonatal Abstinence Syndrome
The purpose of this study is to examine the efficacy of a specially-constructed crib mattress that delivers gentle vibrations (stochastic vibrotactile stimulation) as a complementary, non-pharmacological intervention for treating…
- Trial name
- NCT02801331
- Testing
- Stochastic Vibrotactile Stimulation (SVS)
- Where
- United States
- Volunteers
- 208 people
- Sponsor
- Elisabeth B Salisbury
Youths At-risk for Drug Use/Abuse
Neurological Influences on Drug Prevention Intervention
In this R01 study, a randomized clinical trial is proposed to evaluate the efficacy of a drug abuse prevention intervention for indicated middle school youth that coordinates family and teen-based components.
- Trial name
- NCT00198939
- Testing
- Integrated Family and Cognitive-Behavioral Drug Prevention Intervention, Psychoeducation
- Where
- United States
- Volunteers
- 330 people, healthy volunteers welcome
- Sponsor
- University of Florida
Juvenile Justice Involvement, Drug Abuse
Prevention Program for Problem Behaviors in Girls in Foster Care
This study will determine the efficacy of a parent-involved intervention in preventing problem behavior in middle school girls who are currently in foster care.
- Trial name
- NCT00239837
- Testing
- Middle School Success Intervention (MSS)
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Oregon Social Learning Center
Attention Deficit Disorder With Hyperactivity, Conduct Disorder
Brain Indices of Stimulant Treatment in Drug-Naive Youth at Risk for Substance Use Disorder
Childhood ADHD and comorbid oppositional defiant disorder (ODD) and conduct disorder (CD) are considered risk factors for subsequent substance abuse, and youth with both ADHD and ODD/CD are at greatest risk.
- Conditions
- Attention Deficit Disorder With Hyperactivity, Conduct Disorder, Substance Abuse
- Trial name
- NCT04170738
- Testing
- Adderall
- Where
- United States
- Volunteers
- 33 people
- Sponsor
- Jeffrey Newcorn
Adolescent
Development of a Community-based Network for Drug Abusers
Hidden drug abuse remains a significant concern for public health. An appropriate intervention is necessary to encourage hidden drug abusers to report their situations and seek professional help.
- Trial name
- NCT04400526
- Testing
- A video competition, A training workshop, A mass promotional campaign
- Where
- Hong Kong
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- The Hong Kong Polytechnic University
Substance Use Disorder, Delinquency
Early Intervention for Minors in Possession of Alcohol/Drugs: A Feasibility Study
The purpose of this study is to evaluate two brief, sustainable interventions for a sample of 280 adolescents charged with an initial drug-related offense: Motivational Enhancement Therapy (MET) intervention for youth and the…
- Trial name
- MAST1 (NCT01616212)
- Testing
- Motivational Enhancement Therapy /Adol and PW for parents, Motivational Enhancement Therapy for adolescents, Drug Education for adolescents, Parenting Wisely for parents
- Where
- United States
- Volunteers
- 239 people, healthy volunteers welcome
- Sponsor
- Oregon Research Institute