Clinical trials: Active Cancer
Leukemia
Physical Activity Adapted at Home Supervised by Videoconferencing in Post-cancer for Children / AYA Treated for Leukemia (ONCOPED SAPATIC)
Leukemia is the most common form of cancer (29%) in children, adolescents, and young adults (AYA) (CNIB Report, 2017). Current treatments for leukemia (conventional chemotherapy or hematopoietic stem cell transplantation) can…
- Trial name
- NCT04136665
- Testing
- Physical Activity Adapted program
- Where
- France
- Volunteers
- 2 people
- Sponsor
- University Hospital, Montpellier
Adolescent, Young Adult
Utilizing Novel Information Technology to Promote Exercise and Well-Being in Adolescents and Young Adults With Cancer
Adolescents and young adults (AYAs) with cancer have many needs for supportive care that differ from younger and older patients.This includes age-appropriate psychological support for management of distress, as well as supports…
- Conditions
- Adolescent, Young Adult, Cancer, Physical Activity
- Trial name
- AYA-UNITE (NCT03778658)
- Testing
- Physical Activity Intervention
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- Milton S. Hershey Medical Center
Childhood Extracranial Germ Cell Tumor, Extragonadal Embryonal Carcinoma
Active Surveillance, Bleomycin, Etoposide, Carboplatin or Cisplatin in Treating Pediatric and Adult Patients With Germ Cell Tumors
This phase III trial studies how well active surveillance help doctors to monitor subjects with low risk germ cell tumors for recurrence after their tumor is removed.
- Conditions
- Childhood Extracranial Germ Cell Tumor, Extragonadal Embryonal Carcinoma, Germ Cell Tumor, Malignant Germ Cell Tumor
- Trial name
- NCT03067181
- Testing
- Best Practice, Biopsy Procedure, Biospecimen Collection
- Where
- 629 sites in United States, Australia and 7 more
- Volunteers
- 1,780 people
- Sponsor
- Children's Oncology Group
Odontogenic Cysts
Volumetric Changes in Large Cystic Lesions Using Active Decompression and Distraction Sugosteogenesis vs Passive Decompression
Null hypothesis active decompression and distraction sugosteogenesis is not faster than passive decompression in volume reduction of large cystic lesions
- Trial name
- NCT06262802
- Testing
- Active decompression
- Volunteers
- 10 people
- Sponsor
- Radwa Hydar Ragab
Kidney Cancer
Studying Tumor Tissue Samples From Patients Who Have Undergone Surgery for Localized Kidney Cancer
RATIONALE: Studying samples of tumor tissue from patients with cancer in the laboratory may help doctors learn more about changes that occur in DNA and identify biomarkers related to cancer.
- Trial name
- NCT00908739
- Testing
- gene expression analysis, immunohistochemistry staining method, laboratory biomarker analysis
- Sponsor
- Case Comprehensive Cancer Center
Brain Tumor, Vascular Lesion
Factor XIII and Pulmonary Embolism in Neurosurgical Patients
Two studies (Gerlach et al. 2000; Gerlach et al. 2002) described the impact of factor XIII on the risk of prospective hemorrhage for patients undergoing craniotomy.
- Conditions
- Brain Tumor, Vascular Lesion, Factor XIII Deficiency, Pulmonary Embolism
- Trial name
- NCT01106937
- Where
- Germany
- Volunteers
- 130 people
- Sponsor
- Ludwig-Maximilians - University of Munich
T-cell Lymphoma, NK-Cell Lymphoma
A Registry for People With T-cell Lymphoma
The purpose of this registry study is to create a database-a collection of information-for better understanding T-cell lymphoma.
- Conditions
- T-cell Lymphoma, NK-Cell Lymphoma, T-cell Prolymphocytic Leukemia, T-cell Large Granular Lymphocytic Leukemia
- Trial name
- NCT05978141
- Testing
- Optional Blood Sample and Nail Sample
- Where
- 26 sites in United States
- Volunteers
- 1,000 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Modified Radical Mastectomy, Drain Effect
Active Drainage vs. Passive Drainage in MRM
The aim of the study is to compare between active drainage and passive drainage in post-operative seroma formation after modified radical mastectomy in female patient with breast carcinoma as regard of: Primary Outcomes: 1.
- Conditions
- Modified Radical Mastectomy, Drain Effect, Seroma Formation, Brest Cancer
- Trial name
- MRM Drains (NCT07621575)
- Testing
- compare active and passive drain
- Where
- Egypt
- Volunteers
- 157 people
- Sponsor
- MOHAMED GAMAL AHMED ARAKEEB
Acute Myeloid Leukemia (AML), Acute Lymphoblastic Leukemia (ALL)
A Study Evaluating the Safety, Tolerability, Pharmacokinetics and Preliminary Activity of Idasanutlin in Combination With Either Chemotherapy or Venetoclax in Treatment of Pediatric and Young Adult Participants With Relapsed/Refractory Acute Leukemias or Solid Tumors
This is a Phase I/II, multicenter, open-label, multi-arm study designed to evaluate the safety, tolerability, pharmacokinetics, and preliminary efficacy of idasanutlin, administered as a single agent or in combination with…
- Conditions
- Acute Myeloid Leukemia (AML), Acute Lymphoblastic Leukemia (ALL), Neuroblastoma, Solid Tumors
- Trial name
- NCT04029688
- Testing
- Idasanutlin, Venetoclax, Cyclophosphamide
- Where
- 14 sites in United States, Canada and 4 more
- Volunteers
- 38 people
- Sponsor
- Hoffmann-La Roche
Multiple Myeloma
Effects of Exercise in Combination With Epoetin Alfa
The purpose of the study was to determine the effect of Epoetin alfa therapy (short term versus long term) with and without a home-based individualized exercise program that incorporated aerobic and strength resistance training…
- Trial name
- NCT00577096
- Testing
- Epoetin Alfa, Exercise, Autologous Peripheral Blood Stem Cell Transplantation
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- University of Arkansas
Soft Tissue Sarcoma
Preliminary Clinical Study of Entinostat in Children With Malignant Soft Tissue Sarcoma Harboring PAX-family Gene Abnormalities
Pediatric soft tissue sarcomas (STS) are a group of malignant tumors originating from primitive mesenchymal tissues and account for approximately 7% of childhood cancers.
- Trial name
- NCT07888114
- Testing
- Entinostat, VAC/VTC chemotherapy
- Where
- China
- Volunteers
- 16 people
- Sponsor
- Beijing Tongren Hospital
Hematopoietic and Lymphoid Cell Neoplasm, Malignant Solid Neoplasm
Mobile Health and Social Media Physical Activity Intervention Among Adolescent and Young Adult Childhood Cancer Survivors, the StepByStep Study
This phase III trial compares a multi-component mobile health and social media physical activity intervention versus wearing a physical activity tracker alone among adolescent and young adult childhood cancer survivors.
- Trial name
- NCT04089358
- Testing
- Educational Intervention, FitBit, Goal Setting
- Where
- 116 sites in United States, Canada
- Volunteers
- 387 people
- Sponsor
- Children's Oncology Group
Prostate Cancer
Effects of GCP on Prostate Cancer.
Genistein Combined Polysaccharide (GCP) is derived from adding soy powder to shiitake mushrooms. This concentrated mixture is currently being sold in Japan and the United States and is thought to possibly contain properties that…
- Trial name
- NCT00269555
- Testing
- Genistein Combined Polysaccharide (GCP)
- Where
- United States
- Volunteers
- 62 people
- Sponsor
- University of California, Davis
Breast Cancer
Smart Phone Application in Increasing Physical Activity in Breast Cancer Survivors
This pilot clinical trial studies how well a smart phone application works in increasing physical activity in breast cancer survivors.
- Trial name
- NCT03054025
- Testing
- Smart Phone Monitoring Device
- Where
- United States
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Sidney Kimmel Comprehensive Cancer Center at Thomas Jefferson University
Oncology, Hematology
Goal Attainment Scale in Transplantation
The primary aim of this monocentric randomised controlled study is to evaluate the impact of using GAS to maintain the functional abilities of children and adolescents undergoing TCSE.
- Trial name
- GAST (NCT07372690)
- Testing
- GAS group, control group
- Where
- Italy
- Volunteers
- 176 people
- Sponsor
- Azienda Ospedaliera Ospedale Infantile Regina Margherita Sant'Anna
Acute Lymphoblastic Leukemia, Pediatric, Pediatric ALL
Healthy Bones, Healthy Life: Habitual Physical Activity on Bone & Metabolic Health in Pediatric Cancer Survivors
This project will examine habitual physical activity, bone health, and insulin resistance in pediatric acute lymphocytic leukemia (ALL) and lymphoma cancer survivors at two time points: baseline and 6 months.
- Conditions
- Acute Lymphoblastic Leukemia, Pediatric, Pediatric ALL, Pediatric Lymphoma, Bone Loss
- Trial name
- HBHL (NCT04472286)
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of Nebraska
Neoplasms
Implementation of a Program Based on Adapted Physical Activity and Recommendations for Second Cancers Prevention for TYACs
About 700 new cases of cancer are recorded each year among TYAC aged 15 to 25 years old in Rhône-Alpes region (France); more than 200 are treated and supported within the TYAC Department of the Institute of Hematology and…
- Trial name
- PREVAPAJA (NCT03336905)
- Testing
- Physical activity program and prevention after cancer
- Where
- France
- Volunteers
- 25 people
- Sponsor
- Centre Leon Berard
Cancer
Improving Physical Activity Maintenance of Cancer Survivors
Participants enrolled in the BfitBwell Cancer Exercise Program at the University of Colorado Cancer Center will be randomized 1:1 to receive the current BfitBwell program, or BfitBwell plus six, group-based behavior change…
- Trial name
- NCT03976193
- Testing
- BfitBwell program, 6 bi-weekly PA Behavior Change counseling sessions
- Where
- United States
- Volunteers
- 33 people
- Sponsor
- University of Colorado, Denver
Generalized Myasthenia Gravis
A Study to Evaluate Subcutaneous Zilucoplan in Pediatric Participants With Generalized Myasthenia Gravis
The purpose of this study is to assess the pharmacokinetics, pharmacodynamics, safety, tolerability, immunogenicity and activity of zilucoplan (ZLP) in pediatric study participants with generalized myasthenia gravis (gMG).
- Trial name
- ziMyG (NCT06055959)
- Testing
- Zilucoplan
- Where
- 9 sites in United States, Italy and 3 more
- Volunteers
- 8 people
- Sponsor
- UCB Biopharma SRL
Hodgkins Lymphoma, Non-hodgkins Lymphoma
Brown Fat Activity and White Fat Accumulation
White and brown adipocytes differ in their expression of hormones, cytokines, and inflammatory factors, and they modulate different biological functions.
- Trial name
- NCT01517581
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- Children's Hospital Los Angeles