Clinical trials: Activity
Crohn Disease
Personalising Anti-TNF Therapy in Crohns Disease (PANTS)
To develop a cost-effective, individualised anti-TNF treatment strategy for patients with Crohn's disease which maximizes benefit and minimises harm.
- Trial name
- PANTS (NCT03088449)
- Where
- United Kingdom
- Volunteers
- 1,750 people
- Sponsor
- Royal Devon and Exeter NHS Foundation Trust
Patients Hospitalized in a FRC Department
Validation of a SOFMER Activity Scale
A person's dependency is defined as the total or partial inability to perform without helps the necessary activities of daily life due to activity limitations in the usual environment.
- Trial name
- SAS (NCT03116204)
- Testing
- Assessment of score SAS
- Where
- 9 sites in France
- Volunteers
- 152 people
- Sponsor
- Hospices Civils de Lyon
Neurodevelopmental Disorders
The Effect of Physical Activity Autonomic Response of Autism Spectrum
This study will investigate the effect of physical activity on autism spectrum disorder (ASD) in individuals with ASD of different age groups through measuring the hemodynamic, heart activity and respiratory system parameters.
- Trial name
- NCT05725733
- Testing
- Physical Therapy
- Where
- Saudi Arabia
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of Jazan
Electromyography, Muscles
Electromyography Evaluation of the Impacts of Different Insoles in the Activity Patterns of the Lower Limb Muscles
The main objective of this research is to demonstrate that the use of insoles of different hardness in motorcycle riders may cause variations in the electromyographic activity of the lower limb muscles during the race.
- Conditions
- Electromyography, Muscles, Foot Orthoses
- Trial name
- NCT03734133
- Testing
- Foot insoles
- Where
- Spain
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- Universidad de León
Rheumatoid Arthritis AND Apical Periodontitis
Effect of Endodontic Treatment on Inflammatory Markers, Disease Activity and Periapical Healing in Rheumatoid Arthritis Patients With Apical Periodontitis : A Prospective Interventional Study
SUMMARY TITLE: "Effect of endodontic treatment on inflammatory markers, disease activity and periapical healing in rheumatoid arthritis patients with apical periodontitis" RATIONALE: Chronic inflammation plays a pivotal role in…
- Trial name
- NCT06433232
- Testing
- ROOT CANAL TREATMENT
- Where
- India
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- Postgraduate Institute of Dental Sciences Rohtak
Hodgkin Disease, Non-Hodgkin Lymphoma
Most Closely Matched 3rd Party Rapidly Generated LMP, BARF1 And EBNA1 Specific CTL, EBV-Positive Lymphoma (MABEL)
The subject has a type of cancer or lymph gland disease associated with a virus called Epstein Barr Virus (EBV), which has come back, is at risk of coming back, or has not gone away after standard treatments.
- Conditions
- Hodgkin Disease, Non-Hodgkin Lymphoma, Severe Chronic Active Epstein Barr Virus, T/NK-lymphoproliferative Disease
- Trial name
- MABEL (NCT02287311)
- Testing
- MABEL CTLs, Cyclophosphamide, Fludarabine
- Where
- 2 sites in United States
- Volunteers
- 38 people
- Sponsor
- Baylor College of Medicine
Crohn's Disease
Phase III Study of D9421-C 9 mg in Patients With Active Crohn's Disease in Japan
The purpose of this study is to evaluate the clinical efficacy of D9421-C 9 mg once daily compared to Mesalazine 1 g three times a day to patients with mild to moderate active Crohn's disease affecting ileum, ileocecal region…
- Trial name
- NCT01514240
- Testing
- D9421-C capsule 3 mg, Mesalazine tablets
- Where
- 25 sites in Japan
- Volunteers
- 123 people
- Sponsor
- AstraZeneca
Rhinitis, Allergic, Seasonal
7 Day Study of Mast Cell Inhibitor, R926112, in Patients With Symptomatic Seasonal Allergic Rhinitis
This is a study of the effectiveness and safety of a new nasal spray for the relief of the symptoms of seasonal allergies. The agents being compared are: R926112 (a novel anti-allergy medicine), Beconase (beclomethasone…
- Trial name
- NCT00115089
- Testing
- R926112, Beclomethasone dipropionate
- Volunteers
- 375 people
- Sponsor
- Rigel Pharmaceuticals
Cerebral Palsy, Motor Activity
Development of Horse-Riding Program Model for Children With Cerebral Palsy
The purpose of this study is to develop healing riding algorithm applicable in rural riding centers and to apply this to children with cerebral palsy.
- Trial name
- NCT03041818
- Testing
- Horseback riding therapy
- Where
- South Korea
- Volunteers
- 12 people
- Sponsor
- The Catholic University of Korea
Family Health, Happiness and Harmony, Physical Health
Family Drama Project II
A harmonious family relationship has significant effects on the psychological well-being and development of children. Good communication between parents and children is a crucial element for family health, happiness and harmony.
- Trial name
- NCT04048915
- Testing
- Long live drama, Short live drama
- Where
- Hong Kong
- Volunteers
- 7,026 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Pediatric Brain Tumor, Cognitive Impairment
Fitness to Aid the Brain and Cognitive Skills
The study will assess the feasibility of a pilot clinical trial of community-led aerobic exercise training for paediatric brain tumour survivors (PBTS) and the feasibility of a web-based platform to deliver this exercise…
- Trial name
- Fit ABCS (NCT05367076)
- Testing
- Web-based Aerobic Exercise Program
- Where
- Canada
- Volunteers
- 26 people
- Sponsor
- The Hospital for Sick Children
COVID-19
Study to Evaluate the Effects of RO7496998 (AT-527) in Non-Hospitalized Adult and Adolescent Participants With Mild or Moderate COVID-19
This study will evaluate the efficacy, safety, antiviral activity, and pharmacokinetics of study drug RO7496998 (AT-527) compared to placebo in non-hospitalized adult and adolescent participants with mild to moderate coronavirus…
- Trial name
- MORNINGSKY (NCT04889040)
- Testing
- RO7496998
- Where
- 50 sites in Argentina, Belgium and 10 more
- Volunteers
- 216 people
- Sponsor
- Hoffmann-La Roche
Premature Birth
Plasticity of Neonatal Neuronal Networks Temporal Theta Activity, the First Endogenous
Temporal theta slow-wave activity (TTA-SW) in premature infants is a specific signature of the early development of temporal networks, as it is observed at the turning point between non-sensory driven spontaneous local processing…
- Trial name
- NEURONAUX (NCT03677908)
- Testing
- ElectroEncephaloGraphy
- Where
- France
- Volunteers
- 28 people
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Critical Illness
Topical Application of Silver Nanoparticles and Oral Pathogens in Ill Patients
The purpose of this study is to determine whether oral topic silver nanoparticles are effective to reduce potential pathogen microbial loads in mechanical ventilation patients.
- Trial name
- NCT02761525
- Testing
- silver nanoparticles
- Volunteers
- 50 people
- Sponsor
- Universidad Autonoma de San Luis Potosí
Healthy Subjects
Trial Evaluating a 13-valent Pneumococcal Conjugate Vaccine Given With Diphtheria, Tetanus, and Acellular Pertussis Vaccine (DTaP) in Healthy Japanese Infants
Subjects will be randomly assigned to 1 of 3 groups to receive the following vaccines: Group 1: 13-valent pneumococcal conjugate vaccine (13vPnC) and diphtheria, tetanus, and acellular pertussis vaccine (DTaP), Group 2: 7-valent…
- Trial name
- NCT01200368
- Testing
- 13-valent pneumococcal conjugate vaccine (13vPnC), diphtheria, tetanus, and acellular pertussis vaccine (DTaP), 7-valent pneumococcal conjugate vaccine (7vPnC)
- Where
- 32 sites in Japan
- Volunteers
- 551 people
- Sponsor
- Pfizer
Pupillary Dilation Effect During Cycloplegic Refraction
Comparing Efficacy and Safety of CTO0303 in Pediatric Subjects
This is a prospective randomized study compared with active control arm.
- Trial name
- NCT06609525
- Testing
- CTO0303-A, CTO0303-B, CTO0303-C
- Where
- South Korea
- Volunteers
- 156 people, healthy volunteers welcome
- Sponsor
- Taejoon Pharmaceutical Co., Ltd.
Peripheral Artery Disease
Walking Impairment Questionnaire in PAD
Purpose is to test and validate a new questionnaire (the WELCH questionnaire) to estimate walking capacity in patients with claudication
- Trial name
- WELCH (NCT01114178)
- Testing
- questionnaire
- Where
- France
- Volunteers
- 340 people
- Sponsor
- University Hospital, Angers
Psoriasis Vulgaris
A Maximal Use Trial Evaluating the Pharmacokinetic Profile of MC2-01 Cream in Adolescent Subjects
This is a phase 2, open-label, single-group, multicentre trial in which the investigational product, MC2-01 cream, is investigated in adolescent subjects (age 12 to 16 years, 11 months) with clinically diagnosed extensive…
- Trial name
- NCT03819218
- Testing
- MC2-01 cream
- Where
- 2 sites in Czechia, Germany
- Volunteers
- 7 people
- Sponsor
- MC2 Therapeutics
Children, Exercise
Prescription of Exercise in Children
Most pediatric populations do not meet the physical activity (PA) recommendations set by international organizations. The effectiveness of casual PA advice provided during medical consultations has not been adequately assessed…
- Conditions
- Children, Exercise, Physical Activity, Screen Time
- Trial name
- NCT06765460
- Testing
- Medical prescription of exercise, Health Advice
- Where
- Spain
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- University Hospital Virgen de las Nieves
Physical Fitness, Adiposity
Effects of a 10-Week Zumba Program on Adiposity and Flexibility in 8-Year-Old Children
The purpose of this study is to investigate the effects of a 10-week Zumba dance-based exercise program on body fat (adiposity) and flexibility in healthy 8-year-old children.
- Trial name
- NCT07512349
- Testing
- Zumba Dance-Based Exercise Program
- Where
- Turkey (Türkiye)
- Volunteers
- 115 people, healthy volunteers welcome
- Sponsor
- Ege University