Clinical trials: Acute Distress Respiratory
Severe Acute Respiratory Syndrome
The Interaction Between Severe Acute Respiratory Distress Syndrome Viral Proteins and Monocytes
Severe acute respiratory syndrome (SARS) is a new threat to public health since November, 2002. The SARS is highly contagious and is believed to be transmitted by person-to-person through droplet and direct contact.
- Trial name
- NCT00172263
- Testing
- blood sampling
- Where
- China
- Volunteers
- healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Distress Respiratory Syndrome, Weaning Failure
Pressure Support Ventilation Versus Neurally Adjusted Ventilatory Assist in Difficult to Wean Pediatric Patients
This study assessed the effects of NAVA versus Pressure Support Ventilation (PSV) on patient-ventilator interaction in pediatric patients with difficult weaning from mechanical ventilation after moderate Pediatric Acute…
- Trial name
- NCT04360590
- Testing
- pressure support ventilation versus neurally adjusted ventilatory assist
- Volunteers
- 12 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Solid Cancer, Bronchial Endoscopy
Impact of Interventional Endoscopy on Quality of Life in Patients With Acute Respiratory Distress Due to Tumor Compression or Obstruction of the Lower Respiratory Tract
Bronchoscopic endoscopy has shown its effectiveness and reliability for the treatment (desobstruction or prothesis) of tumor-induced bronchial obstructions, particularly in the first few weeks.
- Conditions
- Solid Cancer, Bronchial Endoscopy, Therapeutic Bronchofiberscopy
- Trial name
- ENDoRA (NCT07051161)
- Testing
- bronchoscope
- Volunteers
- 60 people
- Sponsor
- University Hospital, Grenoble
Preterm Birth, Premature
Comparison of the Acute Effects of Chest Physiotherapy Methods Applied in Different Positions in Preterm Newborns
Infants in the neonatal intensive care unit (NICU) may be lost due to risks such as being sensitive, frequent exposure to birth complications and being prone to infection.
- Conditions
- Preterm Birth, Premature, Bronchopulmonary Dysplasia, Respiratory Distress Syndrome
- Trial name
- therapy (NCT05036603)
- Testing
- chest physiotherapy
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Sanko University
Acute Lung Injury, Acute Respiratory Distress Syndrome
Epidemiology Research on Acute Lung Injury/Acute Respiratory Distress Syndrome (ALI/ARDS) in Adult ICU in Shanghai
To survey the prevalence and the mortality of the Acute Lung Injury/ Acute Respiratory Distress Syndrome (ALI/ARDS) in 12 university hospital ICUs in Shanghai.
- Trial name
- NCT01186874
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Tongji University
Acute Respiratory Distress Syndrome, Influenza
STIP: Statin Trial for Influenza Patients
To assess the efficacy and safety of oral rosuvastatin in patients with suspected or confirmed influenza who require intensive care unit (ICU) admission due to respiratory distress.
- Conditions
- Acute Respiratory Distress Syndrome, Influenza, H1N1 Influenza
- Trial name
- STIP (NCT00970606)
- Testing
- Rosuvastatin (crestor)
- Where
- 21 sites in United States
- Volunteers
- 7 people
- Sponsor
- Gordon Bernard
ARDS
Heliox for Neonate With Acute Respiratory Distress Syndrome (ARDS)
Acute respiratory distress syndrome (ARDS) in neonates has been defined, the role of heliox is not clear.This study aimed to determine whether ARDS neonate would benefit from heliox when oxygenation deteriorated on mechanical…
- Trial name
- NCT03217149
- Testing
- heliox combined with MV, MV
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Daping Hospital and the Research Institute of Surgery of the Third Military Medical University
Acute Respiratory Distress Syndrome in Children
PROSpect: Prone and Oscillation Pediatric Clinical Trial
Severe pediatric acute respiratory distress syndrome (PARDS) is a life-threatening and frequent problem experienced by thousands of children each year.
- Trial name
- NCT03896763
- Testing
- Either supine or prone positioning and either CMV or HFOV
- Where
- 49 sites in United States, Argentina and 13 more
- Volunteers
- 600 people
- Sponsor
- University of Pennsylvania
Acute Respiratory Distress Syndrome
Impact of the Transpulmonary Pressure on Right Ventricle Function in Acute Respiratory Distress Syndrome
Pulmonary distension induced by mechanical ventilation physiologically alters right ventricle pre and after-load, hence might lead to right ventricle failure.
- Trial name
- VD-SDRA (NCT04184674)
- Testing
- Pneumotachograph, Esophageal catheter, Transthoracic and / or transesophageal cardiac ultrasound
- Where
- 2 sites in France
- Volunteers
- 50 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Cardiogenic Shock, Cardiac Arrest
China Extracorporeal Life Support Registry
Extracorporeal life support (ECLS), also known as extracorporeal membrane oxygenation (ECMO), is an extracorporeal technique of providing effective cardiac and respiratory support to patients with lungs and/or heart failure.
- Conditions
- Cardiogenic Shock, Cardiac Arrest, Heart Failure, Acute Respiratory Distress Syndrome
- Trial name
- NCT04158479
- Testing
- ECMO
- Where
- China
- Volunteers
- 20,000 people
- Sponsor
- Beijing Anzhen Hospital
Acute Respiratory Distress Syndrome
Open Lung Ventilation in ARDS: The PHARLAP Trial
Some people develop the condition called acute respiratory distress syndrome (ARDS). This is a condition where the lungs have become injured from one of a number of various causes, and do not work as they normally do to provide…
- Trial name
- PHARLAP (NCT01667146)
- Testing
- PHARLAP mechanical ventilation strategy, Control group mechanical ventilation strategy
- Where
- 27 sites in Australia, Ireland and 3 more
- Volunteers
- 115 people
- Sponsor
- Australian and New Zealand Intensive Care Research Centre
Obstetric Complication, Lung Injury, Acute
Lung Ultrasound to Detect Pulmonary Complications in Critically Ill Parturients
This study aims at describing the frequency, timing and type of pulmonary complications detected with lung ultrasound in critically-ill parturients in admitted to a high-dependency unit in Freetown, Sierra Leone.
- Conditions
- Obstetric Complication, Lung Injury, Acute, Pulmonary Disease, Acute Respiratory Distress Syndrome
- Trial name
- LUSIP (NCT03828630)
- Where
- Sierra Leone
- Volunteers
- 168 people
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Acute Respiratory Distress Syndrome
The Oscillation for ARDS Treated Early (OSCILLATE) Trial Pilot Study
Acute respiratory distress syndrome (ARDS) is a common and catastrophic complication of critical illness related to burns, motor vehicle accidents, or overwhelming infection. ARDS kills 40-70% of affected patients.
- Trial name
- OSCILLATE (NCT00474656)
- Testing
- High-frequency oscillation, Conventional lung-open mechanical ventilation
- Where
- 12 sites in Canada, Saudi Arabia
- Volunteers
- 94 people
- Sponsor
- Canadian Critical Care Trials Group
Covid19, COVID-19 Pneumonia
imPulse™ Una Infrasound-to-ultrasound E-stethoscope
This study generates robust, uniform clinical data across emerging COVID-19 strains to train ML/AI algorithms of the Sponsor's imPulse™ Una infrasound-to-ultrasound e-stethoscope for digital diagnostic feature synthesis of…
- Conditions
- Covid19, COVID-19 Pneumonia, COVID-19 Respiratory Infection, COVID-19 Acute Respiratory Distress Syndrome
- Trial name
- NCT04941209
- Testing
- imPulse™ Una infrasound-to-ultrasound e-stethoscope, (PPA >95%) FDA EUA RT-PCR, HR-CT-scan
- Where
- 3 sites in Democratic Republic of the Congo, India and 1 more
- Volunteers
- 702 people
- Sponsor
- Level 42 AI, Inc.
Acute Lung Injury, Acute Respiratory Distress Syndrome
Acute Lung Injury in Children: Epidemiology and Natural History. PEDIATRIC ALIEN.
The investigators propose to perform a one-year prospective audit of all Acute lung injury (ALI)and cute respiratory distress syndrome (ARDS) pediatric patients managed in several ICUs in Spain.
- Trial name
- ALIEN (NCT01131598)
- Where
- Spain
- Volunteers
- 1 people
- Sponsor
- Hospital de Cruces
Acute Respiratory Distress Syndrome
Surfactant Versus Nasal Continuous Positive Airway Pressure (nCPAP) for Respiratory Distress Syndrome in the Newborn ≥ 35 Weeks of Gestation
Term and near term newborns can present acute respiratory distress syndrome (RDS). Surfactant treatment has been shown effective in reducing mechanical ventilation and oxygen treatment durations in the preterm newborn.
- Trial name
- ASPEN (NCT01306240)
- Testing
- Surfactant instillation, nCPAP
- Where
- France
- Volunteers
- 19 people
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Cardiogenic Shock, Malignant Arrhythmias
The Caribbean Registry of Extracorporeal Membrane Oxygenation (ECMO) From the University Hospital in Martinique
The project's main goal is to collect baseline clinical and procedural data as well as to assess clinical outcomes for all patients undergoing VV, VA or VAV ECMO implantation in the French West Indies and Guiana.
- Conditions
- Cardiogenic Shock, Malignant Arrhythmias, Ischemic or Valvular Heart Failure, Drepanocytosis and Thoracic Syndrome
- Trial name
- NCT07351435
- Volunteers
- 1,200 people
- Sponsor
- University of Genova
Acute Respiratory Distress Syndrome
Titration of PEEP During Mechanical Ventilation in Patients With ARDS Using Electrical Impedance Tomography.
Lung units that participate in gas exchange are known as 'recruited' lung. Patients with lung injury suffer from a proportion of units that do not participate in gas exchange (i.e.
- Trial name
- NCT02596178
- Testing
- Electrical Impedance Tomography
- Where
- United States
- Sponsor
- Boston Children's Hospital
Respiratory Distress Syndrome, Adult
Abnormalities in Lung Computed Tomography and Physiological Alterations in Patients With Acute Respiratory Distress Syndrome
The objective of the study is to determine the correlation between the physiological variables and the degree of consolidation in lung computed tomography in patients with acute respiratory distress syndrome
- Trial name
- NCT02799940
- Where
- Argentina
- Volunteers
- 29 people
- Sponsor
- Hospital Regional Rio Gallegos
Acute Respiratory Distress Syndrome, Pediatric Intensive Care Unit
Pediatric Acute Respiratory Distress Syndrome Asia Study
Mortality rates in children with pediatric acute respiratory distress syndrome (PARDS) are higher in Asia compared to other regions.
- Conditions
- Acute Respiratory Distress Syndrome, Pediatric Intensive Care Unit, Mechanical Ventilation
- Trial name
- PARDS Asia (NCT04068038)
- Testing
- Ventilation protocol
- Where
- 19 sites in China, Hong Kong and 8 more
- Volunteers
- 738 people
- Sponsor
- KK Women's and Children's Hospital