Clinical trials: AdV Infection
Respiratory Viral Illnesses: Influenza A/B, RSV, Adenovirus
Residual Sample Collection for Respiratory Viral Panel
Collect de-identified, residual samples to support a clinical trial. Samples may be prospectively or retrospectively collected. Overall Study Objective Obtain clinical performance data to characterize clinical performance of the…
- Trial name
- NCT02049918
- Where
- United States
- Volunteers
- 1,487 people
- Sponsor
- GenMark Diagnostics
Allogeneic Hematopoietic Stem Cell Transplantation
Antigen Specific Adoptive T Cell Therapy for Adenovirus Infection After Hematopoietic Stem Cell Transplantation
The purpose of this study is to determine if it is possible to treat an infection with a cell-based immunotherapy (therapy that uses the patient's own immune system to treat the infection).
- Trial name
- NCT03378102
- Testing
- IFN-gamma-secreting HAdV antigen specific T cells
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Mari Dallas
Viral Infection After HSCT
Adoptive T-cell Therapy for Resistant Viral Infections After Allogeneic HSCT
The aim of the study is to evaluate the adverse events and the efficacy of virus specific T lymphocytes selected in vitro from a family donor to treat some refractory viral infections as Adenovirus (ADV), Ebstein Barr virus…
- Trial name
- VS-TC (NCT05075837)
- Testing
- Virus -specific T cells
- Volunteers
- 10 people
- Sponsor
- Istituto Giannina Gaslini
EBV, CMV
Allogeneic Multivirus - Directed Cytotoxic T Lymphocytes (CTL)
In this study, investigators are trying to see if infusion of T cells (called CTLs) will prevent or treat cytomegalovirus (CMV), Epstein Barr Virus (EBV) and adenovirus (AdV) reactivation or infection.
- Conditions
- EBV, CMV, Adenovirus
- Trial name
- NCT01945814
- Testing
- CTL for CMV seropositive donors, CTL for CMV naïve donors
- Where
- United States
- Volunteers
- 27 people
- Sponsor
- Catherine Bollard
Adenoviral Conjunctivitis
An Evaluation of the Efficacy and Safety of AL-46383A Ophthalmic Solution for the Treatment of Adenoviral Conjunctivitis
The purpose of this study is to evaluate the safety and efficacy of AL-46383A Ophthalmic Solution for the treatment of adenoviral conjunctivitis.
- Trial name
- NCT00901693
- Testing
- AL-46383A Ophthalmic Solution, AL-46383A Ophthalmic Solution Vehicle
- Volunteers
- 452 people
- Sponsor
- Alcon Research
NEPHROSIS, LIPOID
Latent Viral Infection of Lymphoid Cells in Idiopathic Nephrotic Syndrome
The primary purpose of the study is to evaluate the association of a latent infection of lymphoid cells during the first manifestation of steroid sensitive nephrite syndrome.
- Trial name
- Nephrovir (NCT00577525)
- Where
- France
- Volunteers
- 401 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Adenovirus Infections
A Phase 3 Trial to Compare IV BCV Versus IV CDV for Treatment of Adenovirus Infection After Allo-HCT
This randomized, open-label, parallel group, two-arm, multi-center assessment will compare IV BCV with IV CDV in adult and pediatric allogeneic HCT recipients with AdV viremia.
- Trial name
- ENOVIA (NCT07387367)
- Testing
- cidofovir, Brincidofovir
- Where
- 81 sites in United States, Austria and 11 more
- Volunteers
- 180 people
- Sponsor
- SymBio Pharmaceuticals
CMV, EBV
Cytotoxic T Cells to Prevent Virus Infections
In this study, investigators are trying to see if infusion of "m-CTLs" will prevent or treat cytomegalovirus (CMV), Epstein Barr Virus (EBV) and adenovirus (AdV) reactivation or infection after cord blood transplant.
- Conditions
- CMV, EBV, Adenovirus Infections
- Trial name
- NCT01923766
- Testing
- Cytotoxic T lymphocytes (CTLs).
- Where
- 2 sites in United States
- Volunteers
- 10 people
- Sponsor
- Children's National Research Institute
Adenovirus, Adenovirus Disease
Interest of Rapid Typing in Adenovirus Infections.
Proposal of a "rapid typing" technique by a new real-time PCR method, simpler, faster and cheaper than nucleotide sequencing (reference method) for rapid typing in Adenovirus infections.
- Conditions
- Adenovirus, Adenovirus Disease, Genotyping
- Trial name
- TYPADENO (NCT04056546)
- Volunteers
- 296 people
- Sponsor
- University Hospital, Bordeaux
Ebola Virus Disease
Staged Phase 3 Study to Assess the Safety and Immunogenicity of Ebola Candidate Vaccines Ad26.ZEBOV and MVA-BN-Filo
The purpose of this study is the evaluation of the safety and immunogenicity of two candidate Ebola vaccines Ad26.ZEBOV and MVA-BN-Filo, in a 2-dose heterologous regimen.
- Trial name
- EBOVAC-Salone (NCT02509494)
- Testing
- Ad26.ZEBOV, MVA-BN-Filo, MenACWY
- Where
- Sierra Leone
- Volunteers
- 1,023 people, healthy volunteers welcome
- Sponsor
- Janssen Vaccines & Prevention B.V.
Adenovirus Infection
Clinical Grade Adenovirus Specific T Cells for Immunotherapy After Allogeneic Stem Cell Transplantation (CTL-ADV)
Fourteen patients will be included for infusion of adenovirus-specific T-cells generated by a clinical grade IFN-γ based immunomagnetic isolation from a leukapheresis from their original donor or a haploidentical donor, in case…
- Trial name
- CTL-ADV (NCT02851576)
- Testing
- Infusion of ADV specific T cells
- Where
- France
- Volunteers
- 14 people
- Sponsor
- Central Hospital, Nancy, France