Clinical trials: Addiction, Substance
Mental Disorders, Addiction
Integrated Collaborative Care Teams for Youth With Mental Health and/or Addiction Challenges (YouthCan IMPACT)
Among youth, the prevalence of mental health and addiction (MHA) disorders is roughly 20%, yet youth are challenged to access services in a timely fashion.
- Trial name
- NCT02836080
- Testing
- Integrated Collaborative Care Team (ICCT), Treatment as Usual (TAU)
- Where
- 5 sites in Canada
- Volunteers
- 247 people
- Sponsor
- Centre for Addiction and Mental Health
Opioid Use Disorder
Expanding the Youth Opioid Recovery Support (YORS) Intervention for MOUD Adherence to Adolescents With OUD
Despite rising rates of fatal opioid overdoses in the United States, adolescents with OUD are far less likely than adults to receive and be retained on medication for opioid use disorder (MOUD).
- Trial name
- YORS (NCT06774248)
- Testing
- Youth Opioid Recovery Support (YORS)
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Potomac Health Foundations
Substance Use Disorders, Adolescent Behavior
Addiction in Adolescence - Pathomechanisms and Treatment Evaluation
This study aims to investigate the sociodemographic background as well as psychiatric comorbidities of adolescent substance users with substance use disorders.
- Trial name
- MATRIX-A (NCT03444974)
- Testing
- adapted treatment according to the MATRIX-A therapy
- Where
- Germany
- Volunteers
- 450 people, healthy volunteers welcome
- Sponsor
- Technische Universität Dresden
Nicotine Dependence, Cigarettes, Cessation, Tobacco
Reducing Nicotine Addiction in Adolescent Smokers
Adolescents are at risk for tobacco use due to factors such as impulsivity, poor perception, desire to prove themselves, and insufficient neurological development.
- Conditions
- Nicotine Dependence, Cigarettes, Cessation, Tobacco, Cessation, Smoking, Adolescent Problem Behavior
- Trial name
- NCT05477342
- Testing
- Board Game, Tobacco Cesseation Education, Combined İntervention
- Where
- Turkey (Türkiye)
- Volunteers
- 103 people, healthy volunteers welcome
- Sponsor
- Ministry of National Education, Turkey
Substance Use Disorders, Comorbidities and Coexisting Conditions
Adaptation of Community Reinforcement Approach for the Treatment of Drug Addiction
Central idea of the study is to adapt a treatment program for drug addiction treatment indigenously and relapse prevention, and to establish its efficacy.
- Trial name
- NCT06559631
- Testing
- Indigenously Adapted CRA
- Where
- 2 sites in Pakistan
- Volunteers
- 59 people
- Sponsor
- Muhammad Saghir
Health Services Research, Quality of Life
Quality of Life and Addiction Among Hospital Night Workers
The current context of the Covid-19 health crisis leads to an over-solicitation of health systems, with hospital staff in the front line.
- Conditions
- Health Services Research, Quality of Life, Addiction, Substance-Related Disorders
- Trial name
- ALADDIN (NCT04291534)
- Where
- 2 sites in France
- Volunteers
- 1,800 people
- Sponsor
- University Paris 7 - Denis Diderot
Substance Dependence, Compliance
Improving Substance Abuse Treatment Aftercare Adherence and Outcome
Although substance abuse treatment continuing care participation is strongly related to positive treatment outcomes, participation rates are low and few interventions have been developed that improve continuing care adherence and…
- Conditions
- Substance Dependence, Compliance, Treatment Outcome
- Trial name
- NCT00057187
- Testing
- Contracting, Prompting and Reinforcing
- Where
- United States
- Volunteers
- 157 people
- Sponsor
- US Department of Veterans Affairs
Drug Abuse
Hotline Service for Drug-abusing Youth and Young Adults
Aim: Providing peer counselling service delivered by student counsellors with a medical background via a hotline to drug-abusing youth and young adult aged 35 or below. Objectives: i.
- Trial name
- NCT04461314
- Testing
- peer-led counselling
- Where
- Hong Kong
- Volunteers
- 200 people
- Sponsor
- The University of Hong Kong
Substance-related Disorders, Alcohol-Related Disorders
LaunchPad: Supporting Healthy Decisions and Preventing Drug Use After High School
LaunchPad is an online substance use prevention program for high school seniors. The program is designed to help seniors develop skills and make informed decisions as they transition from high school to young adulthood.
- Conditions
- Substance-related Disorders, Alcohol-Related Disorders, Tobacco Use Disorder, Marijuana Use
- Trial name
- NCT07655609
- Testing
- Introduction, Norms re: Protective Behavior Strategies (PBS), Life Skills
- Volunteers
- 5,000 people, healthy volunteers welcome
- Sponsor
- Prevention Strategies, LLC
Drug Misuse, Addiction
Construction of a Risk Screening Tool for New Psychoactive Substance Misuse Among Adolescents and Young Adults
The goal of this observational study is to construct a risk tool available for screening young adults and adolescents at high risk of drug misuse and provides a chance for early intervention to young adults and adolescents at…
- Trial name
- NCT06714578
- Testing
- Questionnaire and Physical Exam
- Where
- China
- Volunteers
- 1,035 people, healthy volunteers welcome
- Sponsor
- Wei XIA, PhD
Drug Addiction, Drug Abuse
Impact of Online Patient Feedback (OQ) to Therapist
Dropout represents one of the largest problems in substance abuse treatment. International and Nordic research show that only 20 - 40 % of substance abusers complete treatment as intended.
- Trial name
- NCT01891045
- Testing
- OQ-45.2 no feedback, OQ-45.2
- Where
- 2 sites in Norway
- Volunteers
- 160 people
- Sponsor
- Oslo University Hospital
Opioid Related Disorders, Opiate Addiction
Evaluation of Changes in Prescribing Behavior of ER/LA Opioid Prescribers
A study will be performed to evaluate changes in prescribing behavior of prescribers of ER/LA opioids
- Conditions
- Opioid Related Disorders, Opiate Addiction, Narcotic Abuse, Drug Abuse
- Trial name
- NCT02920762
- Testing
- on-interventional study - retrospective database review
- Volunteers
- 5,575,834 people
- Sponsor
- ER/LA Opioid REMS Program Companies (RPC)
Mental Health, Substance-Related Disorders
First Face Training Evaluation in Tribal Communities
The goal of this study is to evaluate a culturally grounded training curriculum, First Face for Mental Health, in Tribal communities, using a waitlist controlled trial design.
- Trial name
- NCT05998005
- Testing
- First Face Training Program
- Where
- 9 sites in United States
- Volunteers
- 554 people, healthy volunteers welcome
- Sponsor
- Cambridge Health Alliance
Substance-Related Disorders, Recidivism
Alliances to Disseminate Addiction Prevention and Treatment (ADAPT)
Youth involved in the juvenile justice system (YJJ) bear a disproportionate burden of the addiction crisis. YJJ substance use (SU) is extremely prevalent, with a third of YJJ meeting criteria for a substance use disorder (SUD).
- Conditions
- Substance-Related Disorders, Recidivism, Opioid-Related Disorders, Substance Use
- Trial name
- ADAPT (NCT04499079)
- Testing
- Learning Health System
- Where
- United States
- Volunteers
- 7,316 people
- Sponsor
- Indiana University
Addiction, Addiction Disorders
Evaluation of the ADD'Pro Vocational Reintegration Program (ADD-PRO-EVAL)
The goal of this clinical trial is to evaluate whether an integrated medico-psychosocial vocational support program (ADD'Pro) can improve employment outcomes in adults with substance use disorders receiving care at a specialized…
- Conditions
- Addiction, Addiction Disorders, Substance Use Recovery, Return to Work
- Trial name
- ADD-PRO-EVAL (NCT07520617)
- Testing
- ADD'Pro Program, Standard Care (in control arm)
- Where
- France
- Volunteers
- 100 people
- Sponsor
- University Hospital, Clermont-Ferrand
Cocaine-Related Disorders
Piracetam for Treatment of Cocaine Addiction, Phase II - 4
The purpose of this study is to follow patients in Phase I of an inpatient study in an eight week open label assessment of piracetam in an outpatient treatment program.
- Trial name
- NCT00000199
- Testing
- Piracetam
- Where
- United States
- Sponsor
- University of Pennsylvania
Addiction, Depression/Anxiety
Healing Lodge First Face Training Evaluation Study
The purpose of this study is to evaluate a culturally grounded training program, xaʔtus (meaning First Face) for Mental Health. This program will train community members in how to recognize and respond to youth and adults…
- Conditions
- Addiction, Depression/Anxiety, Trauma, Psychological, Self-harm
- Trial name
- NCT06290180
- Testing
- First Face for Mental Heatlh
- Where
- United States
- Volunteers
- 92 people, healthy volunteers welcome
- Sponsor
- Cambridge Health Alliance
Substance Abuse, Substance Dependence
Improving Outcomes in Psychosis Associated With Substance Use Using Aripiprazole
This project focuses on the under-researched group of individuals who develop psychotic episodes of short duration (less than four weeks) while using substances.
- Trial name
- SIP (NCT01155544)
- Testing
- Behavioral Intervention
- Where
- 2 sites in United States
- Sponsor
- Northwell Health
Cigarette Smoking-Related Carcinoma
Electronic Cigarette Use During Pregnancy
Aim 1: To compare the overall toxicant exposure in pregnant women who use electronic cigarettes (e-cigs, vapor, e-liquid, e-juice, vape, vaping devices) compared to women who smoke conventional cigarettes. Aim 2.
- Trial name
- NCT03480373
- Where
- 6 sites in United States
- Volunteers
- 182 people
- Sponsor
- UConn Health
Homelessness, Substance Use Disorder (SUD)
Coordinated Access for Addiction Recovery and Equity in VA Supportive Housing
The Department of Housing and Urban Development-VA Supportive Housing (HUD-VASH) Program provides subsidized permanent housing with case management to homeless-experienced Veterans (HEVs).
- Trial name
- CARE-VASH (NCT07141394)
- Testing
- Medication for Addiction Treatment (MAT), Cognitive Behavioral Therapy for Substance Use Disorders (CBT-SUD)
- Where
- United States
- Volunteers
- 7,908 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development