Clinical trials: Adherence
Asthma
Launching an Asthma Initiative Designed to Improve Asthma Management and Outcomes
Following on from a 10 year study conducted in Finland this study is designed to test the validity and sustainability of an enhanced asthma management model for the UK.
- Trial name
- NCT02140671
- Volunteers
- 33,370 people
- Sponsor
- Research in Real-Life Ltd
Patient Satisfaction
Group Based Care Versus Individual Care
The Study compares group based care versus individual given care-effects on patient satisfaction and health. Midwives will be randomized to either traditional antenatal care (Individual care) or group based antenatal…
- Trial name
- GBAC (NCT01224275)
- Testing
- group based care
- Where
- Sweden
- Volunteers
- 1,150 people
- Sponsor
- Karolinska Institutet
HIV, Patient Acceptance of Health Care
Network Supported Engagement In HIV Care
The Network Supported Engagement in Care (NSEC) intervention is a brief, theory based and culturally sensitive intervention designed to capitalize on organic yet underutilized social support networks in the lives of young black…
- Trial name
- NSEC (NCT01726712)
- Testing
- Supportive Care
- Where
- United States
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- University of Chicago
Adolescent Behavior, Psychosocial Functioning
Intervention to Enhance Coping and Help-seeking Among Youth in Foster Care
This study will deploy a scalable secondary prevention program that leverages existing foster youth transition services to improve mental health functioning and service use before and after exiting foster care.
- Conditions
- Adolescent Behavior, Psychosocial Functioning, Coping Behavior, Help-Seeking Behavior
- Trial name
- NCT06019377
- Testing
- Stronger Youth Networks and Coping (SYNC)
- Where
- United States
- Volunteers
- 106 people
- Sponsor
- Portland State University
Heart Failure
Home Care for the Patient With Heart Failure: Can Caregiver Education Prevent Hospital Admissions?
The study is aimed to evaluate if the education of the caregiver is able to reduce hospital admissions of patients with heart failure assisted at home.
- Trial name
- NCT03389841
- Testing
- Education
- Volunteers
- 434 people
- Sponsor
- Maria Stella Padula
Familial Hypercholesterolemia, Adherence, Medication
The Use of Mobile Health Technology and Behavioral Economics to Encourage Adherence in Adolescents
Familial hypercholesterolemia (FH) affects over one million Americans and increases the risk of cardiovascular disease (CVD) by as much as 20-fold.
- Trial name
- NCT04458766
- Testing
- Monetary incentives
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- Boston Children's Hospital
PrEP, HIV Prevention
The Community PrEP Study to Assess the Acceptance of PrEP Delivered Through CBCT Platforms
The investigators aim to 1) speed up access to and delivery of PrEP to young women, and 2) compare interventions to support and maximize the prevention-effective use of PrEP.
- Conditions
- PrEP, HIV Prevention, Adolescence, Cost-effectiveness
- Trial name
- NCT03977181
- Testing
- Group-based Community Health Club, Individual-based Adherence Support
- Where
- South Africa
- Volunteers
- 480 people, healthy volunteers welcome
- Sponsor
- Foundation for Professional Development (Pty) Ltd
Viral Resistance, Treatment Failure
Virologic Treatment Failure and Drug Resistance in HIV-infected Kenyan Children (RESPECT)
The primary objective of this study is to use a well-characterized pediatric AMPATH cohort, with detailed medication-taking, drug level, and clinical data, to longitudinally evaluate treatment failure and drug resistance to…
- Trial name
- RESPECT (NCT03120065)
- Testing
- Electronic Dose Monitoring (MEMS)
- Where
- Kenya
- Volunteers
- 499 people
- Sponsor
- Rachel Vreeman, MD, MS
Medication Adherence, Liver Transplant Disorder
Text Messages for Liver Transplant Recipients
Although medical advancements have enabled children experiencing liver transplants to live longer, medical management post-transplant is ongoing and complex.
- Trial name
- NCT04995770
- Testing
- Praise Text Messages
- Where
- United States
- Volunteers
- 35 people
- Sponsor
- Children's Hospital Los Angeles
Malocclusion, Compliance, Patient
The Effectiveness of Electronic Reminders in Improving Elastic Compliance in Orthodontic Patients
Fixed orthodontic appliances in combination with intraoral elastics are a common and effective method use in the orthodontic correction of malocclusions. However, their success is largely dependent on the patient's compliance.
- Trial name
- NCT03144323
- Testing
- Reminders
- Where
- 2 sites in United Kingdom
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- Guy's and St Thomas' NHS Foundation Trust
Cystic Fibrosis
Investigating the Use of a Positive Parenting Programme to Improve Treatment Adherence in Cystic Fibrosis
Cystic fibrosis (CF) is an illness that makes the lungs clog up with sticky mucus. There is no cure and so treatments are used to help make the illness easier to live with.
- Trial name
- NCT02501369
- Testing
- Self-directed Teen Triple P
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Emma Wells
Asthma
Symbicort SMART (Symbicort Maintenance And Reliever Therapy)
The purpose of this study is to investigate the extent of Symbicort use in patients prescribed Symbicort as maintenance and reliever therapy.
- Trial name
- SMART (NCT00523679)
- Where
- 3 sites in South Korea
- Volunteers
- 2,000 people
- Sponsor
- AstraZeneca
Osteosarcoma, Ewing Sarcoma
Adherence to a Personalized Home Exercise Program in Patients With Bone Tumor Undergoing Lower Extremity Salvage Surgery
The objective of this study is to describe adherence to a personalised home exercise program in patients undergoing resection and reconstruction of lower limb for bone tumor and neoadjuvant chemotherapy treatment in the first six…
- Conditions
- Osteosarcoma, Ewing Sarcoma, Chondrosarcoma, Bone Tumor
- Trial name
- ADER (NCT05779670)
- Where
- Italy
- Volunteers
- 50 people
- Sponsor
- Istituto Ortopedico Rizzoli
Cystic Fibrosis
Impact of the Introduction of ORKAMBI on Anxiety, Depression, Quality of Life and Adherence of Adolescents and Young Adults
The aim of this project is to evaluate the psychological reshuffle induced by ORKAMBI. The particular focus of this study is the consequence of its introduction on anxiety, depression, quality of life and adherence to all cystic…
- Trial name
- ORK-AJA (NCT03659214)
- Testing
- Questionnaires
- Where
- France
- Volunteers
- 19 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Orthodontic Brackets
Damon vs MBT Braces: Patient Compliance and Treatment Efficiency
Comparison between two bracket prescription systems, MBT and DAMON Ultima brackets and evaluate whether the changes incorporated in DAMON Ultima brackets can drive earlier improvement on teeth position, clinically visual…
- Trial name
- NCT07185087
- Testing
- passive self-ligating, Damon Ultima brackets, Conventional ligation, MBT brackets
- Where
- Iraq
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- University of Baghdad
Medication Palatability
Acceptability of Various Available Midazolam Formulations (Syrup, Rectal Suppository, Oro-dispersible Minitablet) in Clinical Practice
This observational study aims to gain knowledge on how the different midazolam formulations (oral syrup, rectal suppository, ODMT) are accepted by 2- to 10-year-old pediatric inpatients and outpatients at the University…
- Trial name
- NCT05894057
- Testing
- Data collection on acceptability of midazolam administration by 2- to 10-year-old pediatric patients at UKBB
- Where
- Switzerland
- Volunteers
- 100 people
- Sponsor
- University Children's Hospital Basel
Tuberculosis
Investigation of a Novel Approach to Improve Treatment Success Rates for Tuberculosis Patients in Senegal
Tuberculosis (TB) patients who receive inadequate treatment or do not complete therapy are more likely to remain infectious, thus contributing to the continuous spread of TB infection in communities.
- Trial name
- NCT00412009
- Testing
- Comprehensive package of activities
- Where
- Senegal
- Volunteers
- 1,500 people
- Sponsor
- Institut de Recherche pour le Developpement
Childhood Obesity, Adolescent Obesity
Local Proof of Concept of Evira in Abu Dhabi Study
Evira is a digital treatment tool developed for treatment of childhood obesity. Through daily weighings at home using a special scale together with a message function in the Evira application, parents and the clinicians can…
- Conditions
- Childhood Obesity, Adolescent Obesity, Treatment Adherence
- Trial name
- NCT06665893
- Testing
- Digi-physical treatment tool
- Where
- United Arab Emirates
- Volunteers
- 70 people
- Sponsor
- Sheikh Shakhbout Medical City
Vaccine-Preventable Diseases, Vaccine Refusal
Volatility and Heterogeneity of Vaccine Sentiments Means Continuous Monitoring is Needed When Measuring Message Effectiveness
The success of vaccination programs often depends on the effectiveness of the vaccine messages, particularly during emergencies such as the COVID-19 pandemic.
- Trial name
- NCT05499299
- Testing
- Google ads
- Where
- Hong Kong
- Volunteers
- 127,000 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Adherence, Engagement
MyPocketPal Feasibility Study
Participants will take part in a 4-week study consisting of two in-person sessions. During the first session, participants will complete a demographic form and baseline questionnaire, after which the study application will be…
- Trial name
- NCT07668843
- Testing
- MyPocketPal, Control
- Where
- Singapore
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Nanyang Technological University
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