Clinical trials: Adiposity
Pro-opiomelanocortin (POMC) Deficiency Obesity
Setmelanotide for the Treatment of Early-Onset Pro-Opiomelanocortin (POMC) Deficiency Obesity
To demonstrate statistically significant and clinically meaningful effects of setmelanotide on percent body weight change in participants with pro-opiomelanocortin (POMC) deficiency or proprotein convertase subtilisin/kexin type…
- Trial name
- NCT02896192
- Testing
- Setmelanotide
- Where
- 7 sites in United States, Belgium and 5 more
- Volunteers
- 15 people
- Sponsor
- Rhythm Pharmaceuticals, Inc.
Diabetes Mellitus, Type 1
Bright 1 Bodies Weight Management Program
Physical inactivity occurs among 65% to 95% of youth with type 1 diabetes (T1D) and based upon limited evidence may contribute to the rapidly growing incidence of overweight among this population.
- Trial name
- B1B (NCT02768987)
- Testing
- Bright 1 Bodies
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Yale University
Healthy, Overweight
Examining the Longitudinal Relationship Between Sleep and Weight Gain in College Students
This two-year prospective, observational study examines the relationship between habitual short sleep and weight gain, as well as the association between habitual short sleep and behaviors that put people at risk of weight gain.
- Trial name
- STARLIT (NCT04100967)
- Where
- United States
- Volunteers
- 116 people, healthy volunteers welcome
- Sponsor
- Oakland University
Behavior, Health, Child Obesity
Greenlight Plus Study: Approaches to Early Childhood Obesity Prevention
A randomized controlled trial enrolling 900 parent-infant dyads (English and Spanish speaking) comparing Greenlight (control), a behavioral intervention focusing on nutrition, physical activity, media use, and sleep as compared…
- Trial name
- NCT04042467
- Testing
- Greenlight Plus, Greenlight
- Where
- 6 sites in United States
- Volunteers
- 900 people, healthy volunteers welcome
- Sponsor
- Vanderbilt University Medical Center
Obesity
Environmental Chemicals That Accumulate in Fat
A crucial factor in evaluating the risk of dioxins, and related endocrine disruptor compounds (dioxins for short) in the human population is the accumulation of these chemicals in the human body.
- Trial name
- NCT03726567
- Testing
- Bariatric surgery
- Where
- United Kingdom
- Volunteers
- 80 people
- Sponsor
- Hull University Teaching Hospitals NHS Trust
Obesity
Effect of Exercises on Physical Health and Cardiorespiratory Fitness in Obese Women
The study will be a Randomized clinical trial and will be conducted in services hospital lahore. The sample size of 50 patients will be taken in this study to find the effects of high intensity interval training versus moderate…
- Trial name
- NCT05618899
- Testing
- HIGH INTENSITY INTERVAL TRAINING, MODERATE INTENSITY EXERCISE
- Where
- Pakistan
- Volunteers
- 50 people
- Sponsor
- Riphah International University
Covid-19, Obesity, Childhood
COVID-19, Obesity and Lifestyle in Children
This study aims to evaluate the impact of the COVID-19 pandemic and its measures on lifestyle in Dutch children between 4 - 18 years.
- Conditions
- Covid-19, Obesity, Childhood, Lifestyle, Lifestyle, Healthy
- Trial name
- COLC (NCT04411511)
- Testing
- Exposure to the Dutch measures due to the Covid-19 pandemic.
- Where
- Netherlands
- Volunteers
- 4,000 people, healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center
Asthma in Children, Dyspnea; Asthmatic
Mechanisms for Dyspnea on Exertion in Children With Obesity and Asthma: Distinct Physiological Phenotypes
The overall objective of this study is to better understand the respiratory mechanisms provoking dyspnea on exertion in obese asthmatic children.
- Conditions
- Asthma in Children, Dyspnea; Asthmatic, Obesity, Childhood
- Trial name
- NCT04184609
- Testing
- Control, Albuterol
- Where
- United States
- Sponsor
- Ohio State University
Diabetes Mellitus Type 2
A Study to Evaluate BMS-986036 in Obese Adults With Type-2 Diabetes
The purpose of this study is to assess the potential of BMS-986036 for treatment obese adults with type-2 diabetes.
- Trial name
- NCT02097277
- Testing
- BMS-986036
- Where
- 16 sites in United States, Canada
- Volunteers
- 219 people
- Sponsor
- Bristol-Myers Squibb
NAFLD, Fatty Liver
Low Carbohydrate Diet: The Effects on Non Alcoholic Fatty Liver Disease in Obese Teens With Metabolic Syndrome
Concurrent with the rising prevalence of childhood obesity, the co-morbid condition of non-alcoholic fatty liver disease (NAFLD) has become the leading cause of chronic liver disease among children.
- Conditions
- NAFLD, Fatty Liver, Obesity, Metabolic Syndrome
- Trial name
- NAFLD (NCT02358928)
- Testing
- Diet Intervention
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- University of Texas Southwestern Medical Center
Weight Loss, Pediatric Obesity
iAmHealthy Parents First: A Televideo Parent and Child Obesity Program for Rural Families
The purpose of this study is to assess whether providing a parent-only group program before providing a parent and child group program works better than the parent and child group program alone.
- Trial name
- NCT05612971
- Testing
- iAmHealthy Parents First, iAmHealthy
- Where
- United States
- Volunteers
- 410 people
- Sponsor
- University of Kansas Medical Center
Child Obesity
Using Video Gaming to Evaluate Front of Pack Labeling With Children
Regulated nutrition information is complex, using decimal places and percentages. Front of pack (FOP) labels provide simplified nutrition information on the front of packages.
- Trial name
- NCT03482336
- Testing
- Four FOP label designs
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Michigan State University
Obesity, Childhood
Addressing Health Disparities in Childhood Obesity, One Summer at a Time
Almost 50% of Native American and Hispanic children are overweight or obese by the 5th grade. Research has demonstrated that the 'obesity gap' facing minority students is largely due to summer weight gain.
- Trial name
- NCT03595332
- Testing
- Summer activity program
- Where
- United States
- Volunteers
- 222 people, healthy volunteers welcome
- Sponsor
- Northern Arizona University
Sleep, Obesity
Enhancing Sleep Duration: Effects on Children's Eating and Activity Behaviors
The proposed study aims to determine whether an intervention to increase sleep in school-age children is associated with positive changes in eating, activity behaviors and zBMI.
- Trial name
- NCT01508793
- Testing
- Optimize Sleep
- Where
- 2 sites in United States
- Volunteers
- 103 people
- Sponsor
- The Miriam Hospital
Overweight Children With Type 2 Diabetes Risk
Prevention of Diabetes in Overweight/Obese Preadolescent Children
Background: The global pandemic obesity has led to increased risk for prediabetes and type 2 diabetes (T2D). Objectives: (i) To evaluate the effect of a 22 weeks multidisciplinary intervention program including exercise on T2D…
- Trial name
- PREDIKID (NCT03027726)
- Testing
- lifestyle and psycho-educational program, Exercise plus lifestyle and psycho-educational program
- Where
- Spain
- Volunteers
- 84 people
- Sponsor
- University of the Basque Country (UPV/EHU)
Cardiovascular Diseases, Heart Diseases
Obesity Prevention for Pre-Adolescents
To develop and evaluate, in a randomized controlled trial, a comprehensive obesity prevention program for third, fourth and fifth grade students.
- Conditions
- Cardiovascular Diseases, Heart Diseases, Obesity
- Trial name
- NCT00185978
- Testing
- diet, physical activity, reduced sedentary behavior
- Where
- United States
- Volunteers
- 900 people, healthy volunteers welcome
- Sponsor
- Stanford University
Obesity
Specially Designed Eating Plates Effects on Food Intake in Normal Weight and Overweight Children
Previous studies demonstrated that children served themselves more food when using larger plates and bowels. The purpose of this study is to evaluate if self-served portions and caloric intake in normal weight and overweight…
- Trial name
- NCT02166892
- Testing
- Specially designed plates
- Where
- Israel
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Dan Nemet, MD
Obesity, Childhood
Nutritional Intake and Gut Microbiome
Pediatric obesity has been increasing in prevalence, but concerns have been raised around the world because no treatment has been found. Recently, however, research on gut microbiome has begun to become a new alternative.
- Trial name
- NCT03388411
- Testing
- Gut microbiome profiling
- Where
- South Korea
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- Hallym University Kangnam Sacred Heart Hospital
Obesity, Physical Activity
A Participatory Parental Intervention Promoting Physical Activity in Preschools
The aim of this study is to test whether a parent-focused participatory intervention in addition to gym lessons can enhance preschoolers physical activity compared to gym lessons alone.
- Trial name
- NCT00987532
- Testing
- parent-focused intervention, twice weekly gym lessons
- Where
- Germany
- Volunteers
- 1,047 people, healthy volunteers welcome
- Sponsor
- Universitätsmedizin Mannheim
Childhood Obesity
FOR HEALTH: A Family-oriented Healthy Eating, Activity and Lifestyle Intervention for Overweight Preschool Children
In this 3-phase study, following an initial small-scale (phase 1) feasibility trial, the aim of phase 2 of the project is to investigate whether a community-based, 12-month intervention for overweight and obese preschool children…
- Trial name
- FOR HEALTH (NCT01698606)
- Testing
- Multidisciplinary, family-centered lifestyle intervention with behavioral counseling
- Where
- Canada
- Volunteers
- 11 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
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