Clinical trials: Adolescent Development
Perinatal Condition, Neurodevelopmental Disorders
Perinatal and Psychological Correlates of Neurodevelopmental Disorders in Children.
The goal of this observational study is to investigate perinatal, cognitive and social-emotional correlates of neurodevelopmental disorders and educational difficulties in children and adolescents.
- Conditions
- Perinatal Condition, Neurodevelopmental Disorders, Social Functioning, Child Development
- Trial name
- NCT06215092
- Testing
- Psychological assessment
- Where
- Poland
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Bartosz M. Radtke
Autism Spectrum Disorder (ASD)
Omega-3 Fatty Acids Monotherapy in Children and Adolescents With Autism Spectrum Disorders
The primary aim of this study is to examine the efficacy and tolerability of short-term omega-3 fatty acids monotherapy in youth with Autism Spectrum Disorders (ASD).
- Trial name
- NCT01248130
- Testing
- Omega-3 Fatty Acid
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- Massachusetts General Hospital
Child Development
LEAPS-NCHD Program Evaluation
An estimated 88 million children drop out of primary school each year worldwide, and the highest number of dropouts are in the first and second grade.
- Trial name
- NCT03764436
- Testing
- LEAPS-NCHD Program
- Where
- Pakistan
- Volunteers
- 3,858 people, healthy volunteers welcome
- Sponsor
- Harvard School of Public Health (HSPH)
Autism Spectrum Disorder, Autism Spectrum Disorder (ASD)
Intranasal Insulin for Autism Spectrum Disorder in Children and Young Adults Aged 4 to 21 Years
This observational study evaluates the real-world use of intranasal insulin in children and young adults with autism spectrum disorder (ASD) utilizing the ViaNase™ device developed by Kurve Therapeutics.
- Conditions
- Autism Spectrum Disorder, Autism Spectrum Disorder (ASD), Autism Spectrum Disorder High-Functioning, Autism Spectrum Disorder With Absence of Functional Language
- Trial name
- IN-INS-AUT (NCT07521371)
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Healing Hope International
Autistic Disorder
Aripiprazole Oral Solution in the Treatment of Children and Adolescents With Autistic Disorder
This is a multicenter, randomized, double-blind, placebo-controlled, parallel-group study to assess the efficacy, safety, tolerability and the steady-state plasma trough concentration of aripiprazole flexible-dosed in children…
- Trial name
- NCT03487770
- Testing
- Aripiprazole Oral Solution
- Where
- China
- Volunteers
- 111 people
- Sponsor
- Otsuka Beijing Research Institute
ADHD - Attention Deficit Disorder With Hyperactivity, Autism Spectrum Disorder
Virtual Reality-assisted Cognitive Rehabilitation in Autistic Youth With ADHD
This study aims to evaluate the effectiveness of a virtual reality-based intervention using the Virtual Reality Rehabilitation System (VRRS) to improve executive functions in autistic and ADHD youth aged 8 to 18 years.
- Trial name
- NCT07426302
- Testing
- VRRS Cognitive Training, Treatment as Usual (TAU)
- Where
- Italy
- Volunteers
- 50 people
- Sponsor
- IRCCS Centro Neurolesi Bonino Pulejo
Autism Spectrum Disorder, Challenging Behaviour
Propranolol for Aggression, Self-Injury, and Severe Disruptive Behavior in Adolescents and Adults With Autism
The goal of this clinical trial is to learn if propranolol can help reduce challenging behaviors associated with Autism Spectrum Disorder, including aggression, self-injury, and severe disruptive behaviors.
- Conditions
- Autism Spectrum Disorder, Challenging Behaviour, Aggression, Severe Disruptive Behaviour Disorders
- Trial name
- NCT07091279
- Testing
- Propranolol
- Where
- 2 sites in United States
- Volunteers
- 60 people
- Sponsor
- Jeremy Veenstra-vanderweele
Heart Defects, Congenital, Executive Dysfunction
EF Intervention in Children With Severe Congenital Heart Disease
Survival rates of children with severe congenital heart disease (CHD) have increased with ongoing medical progress over the past decades.
- Trial name
- E-FIT (NCT05198583)
- Testing
- E-Fit
- Where
- Switzerland
- Volunteers
- 42 people
- Sponsor
- University Children's Hospital, Zurich
Post-COVID-19 Syndrome, Anxiety
Connecting Breath and Mind for CYP With Long COVID
Recruitment target: Phase I: Co-design of intervention: 5 to 15 CYP aged between 12-18 years of age referred to the pan-London long COVID MDT.
- Conditions
- Post-COVID-19 Syndrome, Anxiety, Breathlessness
- Trial name
- NCT05705154
- Testing
- Psychology interventions
- Where
- United Kingdom
- Volunteers
- 40 people
- Sponsor
- Royal Brompton & Harefield NHS Foundation Trust
Autism Spectrum Disorder
A Study to Investigate the Efficacy, Safety, and Tolerability of JNJ-42165279 in Adolescent and Adult Participants With Autism Spectrum Disorder
The purpose of this study is to evaluate the efficacy of JNJ-42165279 compared with placebo in the improvement of symptoms of Autism Spectrum Disorder (ASD) during 12 weeks of treatment using the Autism Behavior Inventory (ABI).
- Trial name
- Envision (NCT03664232)
- Testing
- JNJ-42165279
- Where
- 9 sites in United States
- Volunteers
- 78 people
- Sponsor
- Janssen Research & Development, LLC
Executive Dysfunction
Development and Pilot Testing of a Novel Preschool Executive Function Curriculum
Executive function (EF) skills are a set of essential cognitive abilities that enable individuals to demonstrate their knowledge and talents, effectively complete tasks and navigate social interactions through flexible regulation…
- Trial name
- NCT05135728
- Testing
- Unstuck and On Target: Preschool
- Where
- United States
- Volunteers
- 63 people
- Sponsor
- Children's National Research Institute
Adolescent Development
Adolescent Transition West Africa
This trial will serve as an outcome evaluation of 'Adolescent Transition in West Africa' (ATWA), a school-based program in Mali, Burkina Faso, and Niger for adolescents ages 10-19.
- Trial name
- ATWA (NCT05396664)
- Testing
- ATWA
- Where
- 3 sites in Burkina Faso, Mali and 1 more
- Volunteers
- 4,300 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
Depression, Stress
Development of a Predictive Index for Probable Depression Among Secondary School Students
The present study aims to develop a new predictive index to predict future depression of adolescents by using factors including individual, interpersonal and environmental.
- Conditions
- Depression, Stress, Youth
- Trial name
- NCT04063202
- Testing
- Observation
- Where
- 4 sites in Hong Kong
- Volunteers
- 4,799 people
- Sponsor
- Chinese University of Hong Kong
Polycystic Ovary Syndrome, Hyperandrogenism
Effect of Metformin on Sensitivity of the GnRH Pulse Generator to Suppression by Estradiol and Progesterone
Many, but not all, girls with high levels of the male hormone testosterone go on to develop polycystic ovary syndrome (PCOS) as adults.
- Trial name
- NCT01427595
- Testing
- Metformin, Progesterone, estrace
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- University of Virginia
Healthy
Hippocampal and Frontoparietal Development and Inference
The goal of this clinical trial is to test if an intervention used to manipulate memory and inference can improve our understanding of how brain development supports these abilities in healthy adolescent and adult volunteers.
- Trial name
- NCT07199907
- Testing
- Associative Inference, Probabilistic Inference
- Where
- United States
- Volunteers
- 142 people, healthy volunteers welcome
- Sponsor
- University of Texas at Austin
Anxiety, Autism Spectrum Disorder
Adaptation and Feasibility of the Community-Based Anxiety Program Tailored for Autism (CAPTA)
Anxiety is very common in autistic youth. Recently, an intervention has been created by the investigators to target these symptoms in autistic youth in a community setting.
- Conditions
- Anxiety, Autism Spectrum Disorder, Separation Anxiety, Generalized Anxiety Disorder
- Trial name
- NCT06046170
- Testing
- Cognitive Behavioral Therapy, Treatment as Usual
- Where
- 3 sites in United States
- Volunteers
- 32 people
- Sponsor
- Baylor College of Medicine
Achondroplasia
A Clinical Trial to Evaluate Efficacy and Safety of Navepegritide in Adolescents (12 - 18 Years of Age) With Achondroplasia.
The purpose of this clinical trial is to evaluate efficacy and safety of once weekly subcutaneous (SC) doses of navepegritide 100 μg/kg compared to placebo (inactive drug) in adolescents aged 12 to 18 years with Achondroplasia.
- Trial name
- teACH (NCT06732895)
- Testing
- Navepegritide
- Where
- 5 sites in Canada, Denmark and 3 more
- Volunteers
- 25 people
- Sponsor
- Ascendis Pharma A/S
Chronic Toxic Stress, Developmental/ Behavioral Regression in Young Children
(YMP) Young Moms Program
Young Moms Program (YMP) is designed to address systemic barriers to the health and stability of young moms and their children such as the lack of coordination of service delivery or logistical barriers within the health system.
- Trial name
- YMP (NCT05082857)
- Testing
- "traditional" Parents as Teachers (PAT), "hybrid" PAT model
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Wake Forest University Health Sciences
Autism
The Effects of a Clean Room Sleeping Environment on Elemental and Chemical Concentrations in Children With Autism
A child and their parent were asked to participate in a research project that sought to study whether sleeping in a very clean environment for 14 days improved the elimination of chemicals and metals from the child's body.
- Trial name
- NCT02195401
- Testing
- Cleanroom
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- The Children's Institute
Autism Spectrum Disorder
Arbaclofen vs. Placebo in the Treatment of Children and Adolescents With ASD (ARBA)
This study will examine the safety and efficacy of arbaclofen vs. placebo on social function in children and adolescents with Autism Spectrum Disorder (ASD).
- Trial name
- ARBA (NCT03887676)
- Testing
- Arbaclofen
- Where
- 4 sites in Canada
- Volunteers
- 90 people
- Sponsor
- Holland Bloorview Kids Rehabilitation Hospital