Clinical trials: Adolescent Nutrition
Overweight Adolescents
CommitFit App to Facilitate Health Behavior Change in Clinic Adolescents
We conducted a 3-month RCT with 30 adolescents (aged 13-15 years) and their caregivers to evaluate the effectiveness of the novel mHealth app "CommitFit", which uses gamification to motivate users to log and achieve health…
- Trial name
- NCT06985251
- Testing
- gamified mHealth lifestyle app, Attention Control, gamified mHealth app with financial incentives
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Missouri-Columbia
HIV Disease, Vitamin D Deficiency
Vitamin D Supplementation in HIV-infected Youth
Along with its effects on bone metabolism, vitamin D is an important modulator of the immune system. Experimental studies have shown that the active metabolite of vitamin D [1,25(OH)2D] is able to skew the T cell compartment into…
- Conditions
- HIV Disease, Vitamin D Deficiency, Hypovitaminosis D, Hyperparathyroidism
- Trial name
- NCT01656070
- Testing
- oral cholecalciferol 1000000 UI (vitamin D3)
- Where
- Italy
- Volunteers
- 50 people
- Sponsor
- University of Milan
Obesity, Childhood, Hepatic Steatosis
Effect of Polyphenol Supplementation on Hepatic Steatosis and Vascular Compliance
The main objective is to study the effect of polyphenol supplementation on hepatic steatosis as measured by hepatic ultrasound, hepatic magnetic resonance imaging and on intima-media thickness and vascular elastography in obese…
- Conditions
- Obesity, Childhood, Hepatic Steatosis, Intimal Hyperplasia
- Trial name
- NCT03994029
- Testing
- Effect of polyphenols on hepatic steatosis and vascular elastography and intima media thickness
- Where
- Canada
- Volunteers
- 60 people
- Sponsor
- St. Justine's Hospital
Overweight and Obesity
A Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of HRS9531 Injection in Adolescents With Obesity
The aim of this trial is to evaluate the safety, tolerability, pharmacokinetics and pharmacodynamics of HRS9531 injection compared with placebo in adolescents with obesity
- Trial name
- NCT07559136
- Where
- China
- Volunteers
- 48 people
- Sponsor
- Fujian Shengdi Pharmaceutical Co., Ltd.
Obesity and Type 2 Diabetes
Adapting and Assessing the Feasibility of a Telehealth Diabetes Prevention Program for Hispanic Adolescents
Hispanic adolescents are disproportionately burdened by type 2 diabetes (T2D). Social determinants of health (SDoH) serve as barriers to behavior change and participation in disease prevention efforts, especially among vulnerable…
- Trial name
- Fit24+ (NCT06943001)
- Testing
- Fit24+
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Baylor College of Medicine
Pediatric Cancer
Pilot Evaluation of a Healthy Lifestyle Intervention for Adolescent and Young Adult Survivors of Pediatric Cancer
This is a feasibility and acceptability trial to test a newly developed healthy lifestyle intervention for adolescent and young adult survivors of pediatric cancer.
- Trial name
- NCT04839952
- Testing
- Healthy Lifestyles, Education-Only Control
- Where
- United States
- Volunteers
- 59 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins All Children's Hospital
Child Behavior Problems, Parenting Skills
Project HERA (Health, Education, and Relationship-building for Adolescents- Moms and Tots)
Specific Aims: 1. The primary aims of this study are to conduct formative interviews with teen mothers to inform a targeted adaptation of empirically based weight management and parent training programs for teen mothers for their…
- Conditions
- Child Behavior Problems, Parenting Skills, Obesity Prevention
- Trial name
- Project HERA (NCT02200484)
- Testing
- Combined parent training and obesity prevention program, Wellness program (active contact control)
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- University of Massachusetts, Worcester
Obesity
Gamification and Energetic Behavior Changes
Obesity [Body mass index (BMI kg/m2 ≥ 95th percentile)] affects 1 in 5 adolescents in the United States, with 13 million suffering from severe obesity (BMI ≥ 120% > 95th percentile or ≥ 35 mg/kg2).
- Trial name
- NCT03050840
- Testing
- Way to Health
- Where
- United States
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- Children's Hospital of Philadelphia
Nutritional Status, Omega 3 Fat Status
Association of Seafood Consumption and Nutritional Status Among Adolescent Girls
This study examines how seafood consumption, social changes, and climate change affect the nutrition and well-being of adolescent girls in south-western Bangladesh.
- Conditions
- Nutritional Status, Omega 3 Fat Status, Micronutrient Status, Fish Consumption
- Trial name
- AQUAFOOD (NCT07555197)
- Testing
- Assess natural behavior
- Where
- Bangladesh
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
Obesity, Extreme Obesity
Identification and Characterization of Youth With Extreme Obesity
While obese and extremely obese youth are at increased risk of health complications, especially the extremely obese group rarely seek medical care. One of the underlying reasons might be the lack of adequate treatment options.
- Trial name
- YES (NCT01625325)
- Where
- 5 sites in Germany
- Volunteers
- 429 people, healthy volunteers welcome
- Sponsor
- Prof. Dr. Martin Wabitsch
Overweight, Obesity
A Research Study on How Well Cagrilintide and CagriSema Work in Children and Adolescents With Excess Body Weight
This study will look at how well CagriSema and cagrilintide help children and adolescents with excess body weight lose weight. The study has 2 parts: main and extension study.
- Trial name
- NCT07253285
- Testing
- Cagrilintide, Semaglutide
- Where
- 121 sites in United States, Australia and 24 more
- Volunteers
- 460 people
- Sponsor
- Novo Nordisk A/S
Obesity, Life Style, Healthy
LiPO Teen (the Lifestyle in Pregnancy and Offspring Teenagers
The study is a follow-up of a Randomized Controlled Trial (RCT) performed in 2007-10 - the "Lifestyle in Pregnancy" LiP study. The LiP study included 360 pregnant women with BMI ≥30 kg/m2 from Odense University Hospital and…
- Conditions
- Obesity, Life Style, Healthy, Follow-up, Gestational Weight Gain
- Trial name
- NCT05774652
- Testing
- Lifestyle intervention Dietary advise and/or advise on physical activity
- Where
- Denmark
- Volunteers
- 301 people, healthy volunteers welcome
- Sponsor
- Odense University Hospital
Type2 Diabetes, Type 2 Diabetes Mellitus in Obese
Brain Health in Youth With Normal Weight, Overweight and Obesity at Risk for Type 2 Diabetes (T2D)
Investigators propose to study youth across the spectrum of body mass index (BMI) and dysglycemia. This approach will allow investigators to disentangle the relationship of key features of type 2 diabetes (T2D) risk (e.g.
- Conditions
- Type2 Diabetes, Type 2 Diabetes Mellitus in Obese, Dysglycemia, Microvascular Complications
- Trial name
- Metabrain (NCT05277558)
- Testing
- Observational
- Where
- 2 sites in United States
- Volunteers
- 117 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Cardiovascular Diseases, Hypertension
Influence of Insulin on BP Change During Adolescence
To define the relation of insulin resistance during childhood and adolescence to the development of the insulin resistance syndrome in young adulthood.
- Conditions
- Cardiovascular Diseases, Hypertension, Obesity, Insulin Resistance
- Trial name
- NCT00007098
- Volunteers
- 2 people
- Sponsor
- University of Minnesota
Prader Willi Syndrome, Obsessive-compulsive Disorder
Behavioral Treatment of Obsessive-Compulsive Symptoms in Youth With Prader-Willi Syndrome: A Pilot Project
Obsessive-compulsive (OC) symptoms are often present among youth with Prader-Willi Syndrome (PWS). They are also associated with considerable problems in the daily functioning of the child and his/her family.
- Trial name
- NCT00742664
- Testing
- Cognitive-behavioral therapy, Wait-list control
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- University of South Florida
Exercise, Physical Activity
The Active by Choice Today (ACT) Trial to Increase Physical Activity
The increasing prevalence of obesity in U.S. children and adolescents is a major health threat to our society, especially among minority and low social economic status (SES) populations.
- Conditions
- Exercise, Physical Activity, Obesity
- Trial name
- ACT (NCT01028144)
- Testing
- Physical Activity Program, General Health Program
- Where
- United States
- Volunteers
- 1,422 people, healthy volunteers welcome
- Sponsor
- University of South Carolina
Overweight and Obesity
Improving Emotion Regulation Skills Among Adolescents Attempting to Lose Weight
While the prevalence of overweight and obesity among children and adolescents has plateaued, national data indicate that approximately 35% of children and adolescents continue to struggle with overweight/obesity.
- Trial name
- NCT03393221
- Testing
- ER, SBWC
- Where
- United States
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Rhode Island Hospital
Obesity, Abdominal, Adiposity
Probiotics and the Gut Microbiome in Obese Hispanic Youth
This study will recruit 40 obese Hispanic youth (12 - 18 years of age who are greater than or equal to Tanner stage 4) from hospitals, clinics, and community centers.
- Trial name
- NCT03115385
- Testing
- VSL#3
- Where
- United States
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- University of Southern California
Obesity, Adolescent
Insulin Resistance, Lipid Profile, CRP, IL-18 and Carotid Intima-Media Thickness (CIMT) Diameter in Obese Adolescents
Carotid intima-media thickness (CIMT) is a marker for detecting endothelium dysfunction, and has become a non-invasive method that is very useful in detecting and evaluating subclinical atherosclerosis in obese children and…
- Trial name
- CIMT (NCT06152068)
- Where
- Indonesia
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Universitas Airlangga
Nutrition Disorder, Child, Nutrition Disorders in Adolescence
Health and Nutrition Survey on Shenzhen Children
1. Master and analyze the nutritional health, growth and development status of primary and secondary school students in Shenzhen, and discover the main nutritional health, growth and development problems and influencing factors.
- Conditions
- Nutrition Disorder, Child, Nutrition Disorders in Adolescence, Nutritional Deficiency, Nutrition, Healthy
- Trial name
- NCT05244785
- Where
- China
- Volunteers
- 4,500 people, healthy volunteers welcome
- Sponsor
- Shenzhen Center for Chronic Disease Control
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