Clinical trials: Adolescent Substance Abuse
Prevention, Family Function
Familias Unidas: Preventing Substance Abuse in Hispanic Youth
The focus of this study will be to test the Familias Unidas Intervention program among Hispanic 8th graders in the Miami-Dade County Public School System.
- Conditions
- Prevention, Family Function, Substance Use, Sexual Behavior
- Trial name
- NCT01038206
- Testing
- Familias Unidas
- Where
- United States
- Volunteers
- 746 people, healthy volunteers welcome
- Sponsor
- University of Miami
Adolescent Behaviors, Substance Abuse
Linking Families Together Study- A Randomized Trial to Raise Parental Monitoring
In this study, we will evaluate the efficacy and sustainability of the Linking Families Together (LIFT) intervention to improve parental monitoring during the transition from middle to high school a particularly risky time for…
- Trial name
- LIFT (NCT02129153)
- Testing
- LIFT (Parent Information)
- Where
- United States
- Volunteers
- 318 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Depression, Post-traumatic Stress Disorder
Evaluating Implementation Strategies to Scale-up Transdiagnostic Evidence-based Mental Health Care in Zambia
This study utilizes a Hybrid Type 1 multi-arm parallel group randomized control design to compare the effectiveness of an evidence-based treatment (CETA) delivered either in-person or via telephone, compared with a treatment as…
- Conditions
- Depression, Post-traumatic Stress Disorder, Anxiety, Substance Abuse
- Trial name
- NCT03458039
- Testing
- In-person CETA, Telephone CETA, Treatment as Usual (TAU)
- Where
- Zambia
- Volunteers
- 456 people, healthy volunteers welcome
- Sponsor
- Centre for Infectious Disease Research in Zambia
Prevention Harmful Effects
Computerized Alcohol Screening for Children and Adolescents (cASCA) in Primary Care
The purpose of this study is to assess the psychometric properties of a brief screening questionnaire for alcohol problems among 9- to 18-year-old patients in pediatricians' offices, and to pilot test a personalized…
- Trial name
- cASCA (NCT02233946)
- Testing
- computer-facilitated brief intervention
- Where
- 5 sites in United States
- Volunteers
- 871 people, healthy volunteers welcome
- Sponsor
- Boston Children's Hospital
Opioid Use, Traumatic Injury
Opioid Use After Traumatic Injury in Adolescents
Currently, 1 in 8 adolescents continue to receive prescription opioids a year or more after injury. By longitudinally surveying patients, we can identify risk factors and pathways to nonmedical opioid use.
- Conditions
- Opioid Use, Traumatic Injury, Adolescent Behavior, Substance Abuse Disorder
- Trial name
- NCT03628846
- Where
- United States
- Volunteers
- 123 people, healthy volunteers welcome
- Sponsor
- Indiana University
Adolescent Cannabis Use Disorder
Biofeedback for Adolescent Cannabis Use Disorder
The aims of this study are: 1) to estimate the effect size of HRV biofeedback for stress in adolescents undergoing cognitive behavioral therapy (CBT) for cannabis use disorder (primary outcome: Perceived Stress Scale) and 2) to…
- Trial name
- NCT02059083
- Testing
- Heart rate variability biofeedback, CBT
- Sponsor
- Denver Health and Hospital Authority
Substance Use Disorders, Risk Behavior
Culturally Informed Family Based Treatment of Adolescents: A Randomized Trial
This Stage II randomized trial tests Culturally Informed \& Flexible Family Based Treatment for Adolescents (CIFFTA) developed as part of a Stage I treatment development effort and yielding promising preliminary findings.
- Conditions
- Substance Use Disorders, Risk Behavior, Psychiatric Disorders, Family Dysfunction
- Trial name
- CIFFTA (NCT01823250)
- Testing
- Family Therapy based on Structural Family Therapy, Group Therapy, Psychoeducational Sessions
- Where
- United States
- Volunteers
- 190 people
- Sponsor
- University of Miami
Alcohol Abuse
Family Check-Up for Adolescents and Siblings
A two group randomized design will be used to test the primary hypothesis that the experimental intervention will reduce alcohol consumption and alcohol-related negative consequences significantly more than a comparison…
- Trial name
- NCT00925340
- Testing
- Family Check Up, Psychoeducation
- Where
- United States
- Volunteers
- 104 people
- Sponsor
- Brown University
Alcohol Abuse, Tobacco Use Disorder
Computer Adaptation of Screening, Brief MET Intervention to Reduce Teen Drinking
The goal of this project is to evaluate the feasibility, acceptability, and effect size of a new computerized Motivational Enhancement Therapy (cMET) intervention for alcohol-involved adolescents in primary care.
- Conditions
- Alcohol Abuse, Tobacco Use Disorder, Substance Use
- Trial name
- NCT01881841
- Testing
- cMET
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- Boston Children's Hospital
Substance-Related Disorders
Medical Office Intervention for Adolescent Drug Use
The goal of this study is to assess the efficacy of a new intervention based on motivational enhancement therapy among adolescents with a history of substance use.
- Trial name
- NCT00229983
- Testing
- Motivational Enhancement Therapy
- Where
- United States
- Volunteers
- 170 people
- Sponsor
- Boston Children's Hospital
Adolescent Substance Use
Substance Use Prevention in Teen Psychiatric Patients
The earlier a child initiates alcohol and other drug (AOD) use, the greater the risk of long-range problems. This association persists despite changes in national substance use rates over time, indicating its stability and…
- Trial name
- tCheckup (NCT01170013)
- Testing
- Family Check-up, Parent psychoeducation
- Where
- United States
- Volunteers
- 68 people
- Sponsor
- Brown University
Substance Abuse
Teen Success Project
The purpose of this study is to examine the effectiveness of Juvenile Probation Officers (JPOs) delivering Contingency Management (CM) to teens on their caseload who have problems with drug use.
- Trial name
- JPO-CM (NCT03015805)
- Testing
- Contingency Management, Probation as Usual
- Where
- 14 sites in United States
- Volunteers
- 310 people
- Sponsor
- Chestnut Health Systems
Substance Use, Delinquency
Family-based and Adolescent Residential Drug Treatment
The fundamental objective of this study is to compare the effectiveness of an intensive in-home family-based treatment, Multidimensional Family Therapy, with a multifaceted residential treatment, Adolescent Residential Treatment…
- Trial name
- ART (NCT01737632)
- Testing
- Multidimensional Family Therapy (MDFT), Adolescent Residential Treatment
- Where
- 2 sites in United States
- Volunteers
- 113 people, healthy volunteers welcome
- Sponsor
- University of Miami
Substance Abuse
Advancing Adolescent Screening and Brief Intervention Protocols in Primary Care Settings
This proposed study tests the effectiveness and examines the implementation of screening and brief intervention techniques to delay initiation and reduce substance use among adolescents accessing medical care in Federally…
- Trial name
- NCT01523444
- Testing
- computer-assisted Screening & Brief Advice, computer-assisted Screening & Brief Advice Plus
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Treatment Research Institute
Violence, Alcohol Abuse
Tailored Teen Alcohol and Violence Prevention in the Emergency Room (ER)
This study is designed to address both alcohol misuse and violence among adolescents ages 14-18 seeking care in an urban emergency department (ED).
- Trial name
- NCT00251212
- Testing
- Adapted Motivational Interviewing & Skills Training
- Volunteers
- 3,694 people
- Sponsor
- University of Michigan
Substance Use
Adaptive Interventions for Prevention/Intervention for Youth Substance Abuse
The main aim of this formative study is to test and iteratively refine a new mobile phone app, which delivers assessments and tailored intervention content.
- Trial name
- NCT03928756
- Testing
- Push Notifications with Tailored Intervention Content, Push Notifications with Engaging, Non-therapeutic Content, No Push Notifications
- Where
- United States
- Volunteers
- 39 people
- Sponsor
- University of Michigan
Depression, Anxiety
Primary Care Internet-Based Depression Prevention for Adolescents (CATCH-IT)
In this 5-year, two-site randomized clinical trial, we propose to test the efficacy of the CATCH-IT primary care/Internet based depression prevention intervention against Attention Monitoring Psychoeducation (AMPE) in preventing…
- Conditions
- Depression, Anxiety, Externalizing Symptoms, Substance Abuse
- Trial name
- CATCH-IT (NCT01228890)
- Testing
- CATCH-IT, AMPE
- Where
- 4 sites in United States
- Sponsor
- University of Chicago
Adolescent Problem Behavior, Truancy; Unsocialized
Substance Use Interventions for Truant Adolescents
This study evaluates a brief motivation-building intervention for parents and teens to reduce truancy and substance use. It is hypothesized that the motivational intervention will result in better outcomes compared to an…
- Conditions
- Adolescent Problem Behavior, Truancy; Unsocialized, Marijuana Abuse, Truancy; Socialized
- Trial name
- GOALS (NCT03655574)
- Testing
- Motivational + Family Check-up (MET+FCU), Psychoeducation
- Where
- 2 sites in United States
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Brown University
Substance Use Disorders, Substance Abuse
Effects of Core Stabilization Exercises on Pulmonary Functions, Respiratory Muscle Strength and Functional Capacity
In recent years adolescent substance abuse is a serious and growing problem. Substance use among adolescents means the use of alcohol, opiates, amphetamines, inhalants, cocaine, marijuana, benzodiazepines, hallucinogens, and…
- Conditions
- Substance Use Disorders, Substance Abuse, Substance Use
- Trial name
- NCT03461614
- Testing
- Exercise group, Control group
- Where
- Turkey (Türkiye)
- Volunteers
- 49 people
- Sponsor
- Istanbul University
Alcohol Abuse, Alcohol Dependence
Development and Testing of Adolescent Twelve-Step Facilitation
This study is the first to develop and test in a randomized experimental design the efficacy of an integrated 12-step facilitation intervention tailored for young people.
- Conditions
- Alcohol Abuse, Alcohol Dependence, Drug Abuse, Drug Dependence
- Trial name
- NCT01449981
- Testing
- Integrated Twelve-Step Facilitation, Cognitive Behavioral Therapy
- Where
- United States
- Volunteers
- 59 people
- Sponsor
- Massachusetts General Hospital