Clinical trials: Adolescents
Depressive Symptoms
Efficacy and Biological Targets of Response to rTMS Therapy in Youth Depression
Youth depression is a debilitating disorder that exacts enormous social, economic and personal cost. Unfortunately, treatments which are conventionally used to treat adult depression have often modest to no efficacy in youth and…
- Trial name
- NCT02472470
- Testing
- rTMS
- Where
- Canada
- Volunteers
- 20 people
- Sponsor
- Centre for Addiction and Mental Health
Adolescent Overweight, Adolescent Obesity
Improving Sleep, Decision-Making, and Eating in Adolescents With Obesity
This study is being performed to understand the effects of a lifestyle modification and sleep intervention on weight loss outcomes in adolescence.
- Conditions
- Adolescent Overweight, Adolescent Obesity, Sleep, Eating Behaviors
- Trial name
- STAR (NCT06745570)
- Testing
- Lifestyle Modification and Sleep Intervention
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Nemours Children's Clinic
Unverricht-Lundborg Disease
Brivaracetam as add-on Treatment of Unverricht-Lundborg Disease in Adolescents and Adults
The study will compare the efficacy and safety of brivaracetam with placebo in patients with Unverricht-Lundborg disease.
- Trial name
- NCT00357669
- Testing
- Brivaracetam 25 mg, Brivaracetam 50 mg
- Where
- 13 sites in Finland, France and 5 more
- Volunteers
- 50 people
- Sponsor
- UCB Pharma SA
Anxiety, Oncology
Mindfulness-Music Intervention for Adolescents and Young Adults With Cancer
This study is evaluating how well a music therapy program works to improve anxiety and stress in adolescents and young adults receiving cancer treatment.
- Conditions
- Anxiety, Oncology, Stress
- Trial name
- MAYA (NCT03709225)
- Testing
- Music-based meditation
- Where
- United States
- Volunteers
- 38 people
- Sponsor
- Dana-Farber Cancer Institute
Orthodontic Anchorage Procedures
Posterior Segment Intrusion Using Miniplates
Treating hyperdivergent malocclusion accompanied by open bite could be challenging and may be done by several methods as high pull headgear and posterior bite planes or surgically by maxillary impaction in adults.
- Trial name
- NCT02674191
- Testing
- mini-plates supported molar intrusion, Application of ULTRACARE benzocaine 20%,, Administration of , Mepivacaine-l
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Manal El Namrawy
Asthma
A Randomized Study To Evaluate The Efficacy And Safety Of An Investigational Drug In Adolescent And Adult Subjects With Asthma Uncontrolled on Non-steroidal Therapy.
This study is designed to determine if the investigational drug is effective and safe in individuals with asthma.
- Trial name
- NCT00603382
- Testing
- GW685698X
- Where
- 149 sites in United States, Bulgaria and 12 more
- Volunteers
- 599 people
- Sponsor
- GlaxoSmithKline
Internet Addiction
The Use of Nursing-students-led bCBTMI
The use of the internet is very popular in adolescence. Notwithstanding the benefits from the internet, many users are addicted to the internet and develop problematic behaviours which are regarded as "Internet addiction" (IA).
- Trial name
- NCT05897359
- Testing
- bCBTMI, Control
- Where
- Hong Kong
- Volunteers
- 60 people
- Sponsor
- The Hong Kong Polytechnic University
Scoliosis; Adolescence
A New Spinal Orthosis for Adolescent Idiopathic Scoliosis
The new device with digital technology provides a new avenue to enable clinicians to communicate wirelessly with the imbedded core system such that they can adjust the electrical stimulation parameters and retrieve the…
- Trial name
- NCT03825159
- Testing
- Spinal Orthosis with an Integrated System of Electric Surface Stimulation and Heat Sensing, spinal orthosis
- Where
- Taiwan
- Volunteers
- 60 people
- Sponsor
- Changhua Christian Hospital
Self Harm
Multicenter Study to Evaluate the Clinical and Cost Effectiveness of a Youth Culturally Adapted Therapy (YCMAP)
To evaluate the clinical and cost-effectiveness of a youth culturally adapted manual assisted therapy (YCMAP) in Pakistani Adolescents with a history of self-harm
- Trial name
- NCT04131179
- Testing
- Youth Culturally Adapted Manual Assisted Psychological Therapy (Y-CMAP)
- Where
- 3 sites in Pakistan
- Volunteers
- 684 people
- Sponsor
- Pakistan Institute of Living and Learning
Anxiety
Youth Mayo Clinic Anxiety Coach Randomized Controlled Trial
This research study aims to test the feasibility and effectiveness of using the Mayo Clinic Anxiety Coach smartphone app as an addition to traditional therapy for the treatment of anxiety disorders in youth, particularly those…
- Trial name
- NCT02205203
- Testing
- Mayo Clinic Anxiety Coach, Treatment as Usual
- Where
- United States
- Volunteers
- 145 people
- Sponsor
- Stephen Whiteside
Obesity, Overweight
Mobile Attention Retraining in Overweight Female Adolescents
Background: People are constantly exposed to unhealthy foods. Some studies of adults show that training attention away from unhealthy foods might reduce overeating.
- Conditions
- Obesity, Overweight, Binge Eating, Healthy Volunteers
- Trial name
- NCT02977403
- Testing
- Attention Bias Retraining
- Where
- United States
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Sickle Cell Disease
Medication Adherence in Youth With Sickle Cell Disease (SCD)
Youth diagnosed with sickle cell disease (SCD) may have difficulty taking medication as prescribed (adherence). Hydroxyurea (HU) is one medication that youth may take to help manage SCD.
- Trial name
- NCT02143076
- Testing
- Demographic Questionnaire, Medical Adherence Measure Questionnaire, Acceptability Questionnaire
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- St. Jude Children's Research Hospital
Pregnancy in Adolescence, Counseling
Reducing Adolescent Pregnancy
This multi-site study is employing a brief contraception counseling intervention in the Emergency Department (ED) to shed light on factors that affect decision making as well as barriers and facilitators to conception initiation…
- Conditions
- Pregnancy in Adolescence, Counseling, Contraception Behavior
- Trial name
- NCT04120376
- Testing
- Contraception Counseling
- Where
- 2 sites in United States
- Volunteers
- 144 people, healthy volunteers welcome
- Sponsor
- Children's Hospital of Philadelphia
Acne, Quality of Life
Effect of Acne Vulgaris on Quality of Life of Teenagers Compared to Parent Perceived Effect on Quality of Life
Acne vulgaris is a common problem in the adolescent community. Past research has shown that acne affects teenager's self-esteem and mood.
- Trial name
- NCT01835210
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Ann & Robert H Lurie Children's Hospital of Chicago
Obesity
A Phase II, Randomized, Double-blind, Placebo-controlled, in Parallel Groups Clinical Trial to Assess the Safety and Efficacy of Dietary Supplementation With Tryptophan to Achieve Weight Loss, and Its Neuropsychological Effects in Adolescents With Obesity
A phase II, randomized, double-blind, placebo-controlled, in parallel groups clinical trial to assess the safety and efficacy of dietary supplementation with tryptophan to achieve weight loss, and its neuropsychological effects…
- Trial name
- NCT02612259
- Testing
- TRYPTOPHAN
- Volunteers
- 44 people
- Sponsor
- Fundació Sant Joan de Déu
Asthma
Efficacy and Safety of 3 Doses of Tiotropium Compared to Placebo in Adolescents (12 to 17 Yrs) With Moderate Asthma
The primary objective of this trial is to evaluate the efficacy and safety of tiotropium 1.25 mcg (2 actuations of 0.625 mcg), tiotropium 2.5 mcg (2 actuations of 1.25 mcg) and tiotropium 5 mcg (2 actuations of 2.5 mcg) once…
- Trial name
- NCT01122680
- Testing
- Tiotropium bromide
- Where
- 19 sites in United States, Germany and 3 more
- Volunteers
- 105 people
- Sponsor
- Boehringer Ingelheim
Marijuana Abuse
A Real-time, Contextual Intervention Using Mobile Technology to Reduce Marijuana Use in Youth
The purpose of this study is to further develop and test the Momentary Self-Monitoring and Feedback + Motivational Enhancement Therapy (MOMENT) intervention, a real-time, contextual intervention to reduce marijuana use among…
- Trial name
- MOMENT (NCT01762696)
- Testing
- MET, MOMENT
- Where
- 2 sites in United States
- Volunteers
- 70 people
- Sponsor
- Boston Children's Hospital
Lower Limb and Combined Lower Limb and Upper Limb Spasticity Due to Cerebral Palsy
Long-term Open-label Study of Botulinumtoxin Type A to Treat Spasticity of Leg(s) or Leg(s) and Arm in Cerebral Palsy
The purpose of this study is to determine whether injections of Botulinum toxin type A into muscles of the leg(s) or of leg(s) and one arm are safe in treating children/adolescents (age 2-17 years) long-term with increased muscle…
- Trial name
- NCT01905683
- Testing
- IncobotulinumtoxinA (16-20 Units per kg body weight)
- Where
- 43 sites in Austria, Czechia and 10 more
- Volunteers
- 370 people
- Sponsor
- Merz Pharmaceuticals GmbH
Chronic Pain, Chronic Pain Syndrome
Interoceptive Awareness and Function in Adolescents With Chronic Pain
The main objectives of this study are to compare the levels of interoceptive awareness and self-reported function pre and post completion of an occupational therapy treatment plan.
- Conditions
- Chronic Pain, Chronic Pain Syndrome, Pain, Chronic
- Trial name
- NCT07325110
- Testing
- Occupational Therapy
- Where
- United States
- Volunteers
- 49 people
- Sponsor
- Connecticut Children's Medical Center
Contraceptive Usage, Contraception Behavior
Effectiveness Testing of a Videogame Intervention (No Baby No) to Decrease Contraception Non-use Among Adolescents.
The purpose of this study is to evaluate the effectiveness of a videogame compared to an attention/time control at reducing contraceptive non-use among adolescents.
- Trial name
- NCT06990724
- Testing
- Videogame Intervention, Commercial game control
- Where
- 7 sites in United States
- Volunteers
- 850 people, healthy volunteers welcome
- Sponsor
- Weill Medical College of Cornell University
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