Clinical trials: African Americans
HIV
Likely Use of PrEP for African American YMSM
HIV Pre-Exposure Prophylaxis (PrEP), in the form of the anti-retroviral pill Truvada©, has been approved by the FDA as a method for reducing HIV transmission rates in the population, particularly young men who have sex with men…
- Trial name
- NCT02810249
- Testing
- No intervention used
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Duke University
Asthma
Asthma Symptom Based Adjustment of Inhaled Steroid Therapy in African American Children
African American (AA) children carry a disproportionate burden of mortality and morbidity in asthma. A major contributor to racial disparity in asthma is lack of adherence to guideline-recommended use of daily inhaled…
- Trial name
- ASIST (NCT02298205)
- Testing
- Asthma controller medication (Beclomethasone) adjustment strategy, Provider-based adjustment
- Where
- United States
- Volunteers
- 206 people
- Sponsor
- Washington University School of Medicine
Stress, Trauma
Exploring PTSD Symptoms, Barriers and Facilitators to Mindfulness
The purpose of this study is to investigate justice-involved Black/African American female adolescents' (JI BAFAs; N=35) self-reported outcomes: stress, posttraumatic stress disorder (PTSD), recidivism, etc., as well as their…
- Conditions
- Stress, Trauma, PTSD, HPA
- Trial name
- NCT06311188
- Testing
- ITR Healing intervention
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Obesity, Childhood, Metabolic Syndrome
FIT Families Multicomponent Obesity Intervention for African American Adolescents
Obesity is one of the most prevalent medical problems facing children and adolescents today, particularly among African American adolescents where the rate is alarmingly high.
- Trial name
- NCT04974554
- Testing
- FIT, Home-Based Family Support
- Where
- United States
- Volunteers
- 360 people
- Sponsor
- Medical University of South Carolina
Lupus
Improving Quality of Life for African American Female Adolescents With Lupus
This study will evaluate a program designed to help African American adolescents with lupus (systemic lupus erythematosus or SLE) cope with the disease.
- Trial name
- NCT00068874
- Testing
- Coping skills and cognitive restructuring techniques, Educational training
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- Medical University of South Carolina
Healthy
Mexican and African American Family Focus Groups on Puberty
Primary Objective: For focus groups of Mexican American and African-American girls and focus groups of their parents to explore factors that could enhance the conduct of a future study of puberty and body mass.
- Trial name
- NCT00528762
- Testing
- Focus Group
- Where
- United States
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- M.D. Anderson Cancer Center
Sexually Transmitted Infections
Sexually Transmitted Infections Among African American Women Who Have Sex With Women
The purpose of this study is to determine rates of sexually transmitted infections (STIs) among African American women who have sex with women (AAWSW).
- Trial name
- WSHP (NCT01546714)
- Where
- 2 sites in United States
- Volunteers
- 165 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Asthma
Asthma in the Delta Region of Arkansas (ADRA): Prevalence and Morbidity
The purpose of the study is to conduct a cross-sectional study to examine asthma prevalence and morbidity in a predominately minority, low-income population in rural Arkansas.
- Trial name
- NCT00589719
- Where
- United States
- Volunteers
- 964 people, healthy volunteers welcome
- Sponsor
- Arkansas Children's Hospital Research Institute
Correct Consistent Condom Use
A Self-Guided Intervention to Promote Condom Use Among African American Males
The Centers for Disease Control and Prevention has declared that AIDS is a "state of emergency" in the US for African Americans - young African American men are especially vulnerable in this epidemic.
- Trial name
- NCT01536730
- Testing
- Homework Intervention Strategy
- Where
- United States
- Volunteers
- 193 people, healthy volunteers welcome
- Sponsor
- Indiana University
Depression
Preventing Postpartum Depression in African American Home Visiting Clients
The goal of this study is to determine whether a 6 week intervention is effective in preventing the worsening of depressive symptoms and development of clinical depression in low-income African American pregnant and recently…
- Trial name
- NCT01175603
- Testing
- Mothers and Babies Course (Adapted for Baltimore Home Visiting Programs)
- Where
- 4 sites in United States
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
HIV Infections, Sexually Transmitted Infections
HIV Prevention Program for African American Teen Males
The purpose of this study is to test if sexual health interventions can reduce the incidence of STIs among African American teens (15 to 21 years old).
- Trial name
- NCT00849823
- Testing
- Male Sexual Health Program, Focus on the Future Program
- Where
- United States
- Volunteers
- 840 people, healthy volunteers welcome
- Sponsor
- Richard Crosby
Vitamin D Deficiency
Vitamin D Supplementation in Overweight/Obese African American Adults and Youth (D-SUNNY)
Primary Specific Aim 1: To compare the dose-responsive effects of vitamin D3 supplementations on 25(OH) D, parathyroid hormone (PTH), and serum/urine calcium.
- Trial name
- D-SUNNY (NCT01583621)
- Testing
- Cholecalciferol
- Where
- United States
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- Augusta University
Hepatitis B Infection
Effect of Entecavir in Blacks/African Americans and Hispanics With Chronic Hepatitis B Virus (HBV) Infection
The purpose of this clinical research study is to develop observational clinical experience with the use of entecavir in participants who are either of Black/African-American race or of Hispanic ethnicity.
- Trial name
- NCT00371150
- Testing
- Entecavir
- Where
- 27 sites in United States, Brazil and 3 more
- Volunteers
- 131 people
- Sponsor
- Bristol-Myers Squibb
Diabetes Mellitus, Type 2
A Task Analysis Study of DECIDE For African American Patients With Type 2 Diabetes
The Decision-Making Education for Choices in Diabetes Every Day (DECIDE) program (copyrighted) was created by Dr. Felicia Hill-Briggs and is used by permission for the purpose of this pilot study.
- Trial name
- eDECIDE (NCT03855449)
- Testing
- eDECIDE Web-based Intervention Group
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- University of Kansas Medical Center
Asthma
Phase4/Symbicort® Versus Pulmicort Flexhaler® in African Americans
To compare the efficacy of SYMBICORT® pMDI 160/4.5 μg x 2 actuations twice daily (bid) to that of budesonide inhalation powder DPI 180 μg x 2 inhalations bid, in African American(self-reported) subjects with inhaled…
- Trial name
- Titan (NCT00702325)
- Testing
- Budesonide / formoterol fumarate (SYMBICORT), Budesonide
- Where
- 57 sites in United States
- Volunteers
- 311 people
- Sponsor
- AstraZeneca
Vitamin D Deficiency
Vitamin D3 Supplementation Pilot Study
The purpose of this research study is to determine whether taking vitamin D, every day, over a 12 week period will improve the vitamin D status, risks for poor heart health, risks for developing type 2 diabetes, and/or muscle…
- Trial name
- NCT01546103
- Testing
- Cholecalciferol
- Where
- United States
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Children's Hospital of Philadelphia
Gonorrhea, Chlamydia
Safer Sex Program for Young African-American Men
To evaluate the efficacy of the adapted program a randomized controlled trial enrolling 620 eligible African American men who have sex with men (MSM) will be conducted.
- Conditions
- Gonorrhea, Chlamydia, Trichomoniasis, Syphilis
- Trial name
- NCT01439503
- Testing
- Intervention
- Where
- United States
- Volunteers
- 620 people, healthy volunteers welcome
- Sponsor
- Richard Crosby
Coronary Artery Disease
A Trial of Stress Reduction in the Secondary Prevention of Coronary Heart Disease in Blacks
The overall hypothesis of this study is that a cardiac rehabilitation program with meditation will be more effective than cardiac rehabilitation alone in improving blood flow through the diseased coronary arteries in African…
- Trial name
- CCR (NCT01810029)
- Testing
- Cardiac Rehabilitation plus Transcendental Meditation
- Where
- United States
- Volunteers
- 56 people
- Sponsor
- Maharishi International University
Alzheimer Disease
Alzheimer's Disease Treatment and Illness Perceptions Survey (TIPS) II
The TIPS Study, or Treatment and Illness Perceptions Survey, is a study funded by the national Alzheimer's Association to learn more about differences between African Americans' and Whites' attitudes, beliefs, and experiences…
- Trial name
- NCT00059410
- Where
- United States
- Volunteers
- 210 people, healthy volunteers welcome
- Sponsor
- Alzheimer's Association
Violence in Adolescence, Substance Use
BrotherlyACT: A Tech-Enhanced Violence and Substance Use Intervention for Black Boys and Young Men
This study will adapt and test a culturally tailored, multi-component, and trauma-focused digital intervention to reduce the risk and effects of youth violence and substance use and bridge service access gaps for young Black…
- Conditions
- Violence in Adolescence, Substance Use, Avoidance of Healthcare
- Trial name
- BrotherlyACT (NCT06359990)
- Testing
- BrotherlyACT, BrotherlyACT Waitlist Control Group (WCG)
- Where
- United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Rush University Medical Center