Clinical trials: Aggression
Social Competence, Bullying
Effects of ACT OUT! Social Issue Theater on Youth and Adolescents
The ACT OUT! Trial is designed as a proof-of-concept, cluster, randomized, superiority trial with two parallel groups. Although the unit of measurement is student, the unit of randomization is classroom, stratified by school.
- Trial name
- NCT04097496
- Testing
- Act Out! Intervention
- Where
- United States
- Volunteers
- 1,537 people, healthy volunteers welcome
- Sponsor
- Indiana University
Non-Hodgkin Lymphoma
Analysis of Molecular Markers of Drug Resistance in Tumor Biopsies From Previously Untreated Aggressive Non-Hodgkin's Lymphoma
Although the cause(s) of clinical drug resistance in non-Hodgkin's lymphomas (NHL) are unknown, in vitro studies suggest that abnormalities of the cell cycle and mechanisms of apoptosis may play an important role.
- Trial name
- NCT00026910
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- National Cancer Institute (NCI)
Agitation Management, Aggression
Effect of Verbal De-Escalation-Based Simulation on Agitation Management, Perception of Aggression, and Impact of Aggression in Emergency Department Nurses
This mixed-methods randomized controlled study aims to evaluate the effects of verbal de-escalation-based simulation training on emergency department nurses' knowledge of agitation management, perceptions of aggression, and the…
- Conditions
- Agitation Management, Aggression, Verbal De-Escalation
- Trial name
- NCT07784868
- Testing
- Standard Verbal De-Escalation Training, Verbal De-Escalation-Based Simulation Training
- Where
- Turkey (Türkiye)
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- Uskudar University
Prostate Cancer
Evaluation of a Blood Biomarker to Try and Distinguish Between the Presence or Absence of Aggressive Prostate Cancer
A Laboratory Study to Evaluate Urine and Blood Biomarkers That Can Distinguish Between the Presence or Absence of Aggressive Prostate Cancer
- Trial name
- NCT03256630
- Where
- United States
- Volunteers
- 128 people
- Sponsor
- Genomic Health®, Inc.
Sickle Cell Disease
Study of HLA-Haploidentical Stem Cell Transplantation to Treat Clinically Aggressive Sickle Cell Disease
The study is a Phase II clinical trial. Patients will receive intensity modulated total body irradiation (TBI) at a dose of 3 Gy with standard fludarabine/ i.v.
- Trial name
- NCT03121001
- Testing
- ATG, fludarabine, cyclophosphamide
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of Illinois Chicago
Dating Violence
The Effect of an Intervention Based on Implicit Theories of Personality on the Prevention of Adolescent Dating Violence
This study evaluates the efficacy of an intervention based on the Implicit Theories of Personality (ITP) to prevent dating violence in Spanish adolescents.
- Trial name
- NCT03583645
- Testing
- Incremental theory of personality, Educational Intervention
- Volunteers
- 402 people, healthy volunteers welcome
- Sponsor
- University of Deusto
Anger, Hostility
Two Anger Management Programs for Teens.
The general aim of the proposed pilot study is to evaluate the the efficacy of mind-body bridging (MBB) for anger management compared with the Real Deal anger management program, in helping adolescents control or reduce their…
- Conditions
- Anger, Hostility, Aggression
- Trial name
- NCT02001246
- Testing
- Real Deal program for Anger Management, Mind-body Bridging (MBB) program
- Where
- 2 sites in United States
- Volunteers
- 35 people
- Sponsor
- University of Utah
Fibromatosis
A Trial of Imatinib for Patients With Aggressive Desmoid Tumor (Aggressive Fibromatosis)
Aggressive fibromatosis (AF, also known as desmoid tumor) is a fibroproliferative neoplasm that typically arises in the abdomen but can develop at other anatomic sites, most commonly in the extremities.
- Trial name
- NCT02495519
- Testing
- Imatinib
- Where
- South Korea
- Volunteers
- 21 people
- Sponsor
- Yonsei University
Sickle Cell Disease
SCD-Haplo: Phase II Study of HLA-Haploidentical SCT for Aggressive SCD
Related donor stem cell transplantation using the alemtuzumab/ TBI platform has been shown to be a safe strategy to cure severe sickle cell disease.
- Trial name
- SCD-Haplo (NCT02013375)
- Testing
- Haploidentical Transplant, Alemtuzumab, Total Body Irradiation
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- Damiano Rondelli, MD
Lymphoma, T-Cell, Lymphoma, Extranodal NK-T-Cell
Campath-1H and EPOCH to Treat Non-Hodgkin's T- and NK-Cell Lymphomas
Background: The paradigm of combining therapeutic agents with non-overlapping toxicities for the treatment of malignancy produces clinical remissions and cures in a number of tumor types.
- Trial name
- NCT00069238
- Testing
- Alemtuzumab (Campath), EPOCH
- Where
- United States
- Volunteers
- 31 people
- Sponsor
- National Cancer Institute (NCI)
Depression, Bullying
Intervention Based on Implicit Theories of Personality: Effects on Depression and Bullying
This study evaluates the efficacy of an intervention based on the Implicit Theories of Personality (ITP) in Spanish adolescents.
- Trial name
- ITP (NCT03481699)
- Testing
- Incremental theory of personality, Educational Intervention
- Volunteers
- 882 people, healthy volunteers welcome
- Sponsor
- University of Deusto
Multiple Endocrine Neoplasia
Metabolomics and Genetic Diagnosing Pancreatic Neuroendocrine Tumors in MEN1 Patients
Objectives: The aim of the present study is to assess the significance of metabolomics and genetics in diagnosing and survival evaluation for pNET in the periodic follow-up of MEN1 patients.
- Trial name
- NCT03048266
- Where
- United States
- Volunteers
- 629 people, healthy volunteers welcome
- Sponsor
- M.D. Anderson Cancer Center
Aggression
Risperidone Augmentation for Treatment-Resistant Aggression in ADHD
Primary objectives: 1. To assess the short-term efficacy of risperidone augmentation for treatment-resistant aggression in children with ADHD. 2.
- Trial name
- NCT00297739
- Testing
- Risperidone
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Armenteros, Jorge L., M.D., P.A.
Bullying
The Effect of School-Based Bullying Prevention Program on Bullying Victimization, Tendencies and Future Expectations of Adolescents
The aim of this study is to determine the effect of a school-based bullying prevention program on adolescents' bullying victimization, tendencies and future expectations.
- Trial name
- NCT06663215
- Testing
- School Based Bullying Prevention Program
- Where
- Turkey (Türkiye)
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Harran University
Irritable Mood, Aggression
Utility of Amantadine Hydrochloride in the Treatment of Post-traumatic Irritability
The purpose of this study is to determine if amantadine hydrochloride given 100 mg in the morning and at noon is safe and effective in the treatment of mood and behavior changes (i.e.
- Conditions
- Irritable Mood, Aggression, Traumatic Brain Injury
- Trial name
- NCT00627250
- Testing
- Amantadine
- Volunteers
- 76 people
- Sponsor
- Wake Forest University Health Sciences
Conduct Disorder, ADHD
Investigation of Psychophysiological Correlation of Aggression and Response to Aversive Stimuli
This study investigates the psychophysiological correlations of aggression and response to aversive stimuli in a population of 133 children clinically diagnosed with conduct disorder (CD) and/or attention-deficit/hyperactivity…
- Conditions
- Conduct Disorder, ADHD, Oppositional Defiant Disorder
- Trial name
- NCT03725371
- Testing
- No intervention was administered for the purpose of this study.
- Volunteers
- 133 people
- Sponsor
- Yale-NUS College
Social Exclusion, Aggression
Motivational Interviewing-Based Training
The middle school period is the period when children begin to experience physical, emotional and social development and try to adapt to psychological changes.
- Conditions
- Social Exclusion, Aggression, Bullying of Child
- Trial name
- NCT06972030
- Testing
- Motivational interviewing
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Muş Alparslan University
Lymphoma
SWOG-9704 Chemoradiotherapy and Peripheral Stem Cell Transplantation Compared With Combination Chemotherapy in Treating Patients With Non-Hodgkin's Lymphoma
RATIONALE: Drugs used in chemotherapy use different ways to stop cancer cells from dividing so they stop growing or die. Radiation therapy uses high-energy x-rays to damage cancer cells.
- Trial name
- NCT00004031
- Testing
- rituximab, CHOP regimen, carmustine
- Where
- 15 sites in United States, Canada
- Volunteers
- 397 people
- Sponsor
- SWOG Cancer Research Network
Autism, Autism Spectrum Disorder (ASD
Cognitive-Behavioral Therapy for Irritability in Adolescents With High Functioning Autism Spectrum Disorder
In addition to the core symptoms, children and adolescents with Autism Spectrum Disorder (ASD) often exhibit disruptive behavior problems including irritability, tantrums, noncompliance, and aggression.
- Conditions
- Autism, Autism Spectrum Disorder (ASD, Asperger's Disorder, Pervasive Developmental Disorder (PDD-NOS)
- Trial name
- NCT01631851
- Testing
- Cognitive-Behavioral Therapy (CBT) for Irritability
- Where
- United States
- Volunteers
- 9 people
- Sponsor
- Yale University
Aggression
An Evaluation of an Integrated Approach to Prevention and Early Intervention in the Elementary School Years
In this study, the investigators propose to examine whether the combination of a universal, elementary school-based preventive intervention with an indicated preventive and treatment intervention would yield greater impact on…
- Trial name
- P2P+IY (NCT03132805)
- Testing
- PATHS to PAX, PATHS to PAX and the Incredible Years
- Where
- United States
- Volunteers
- 5,233 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins Bloomberg School of Public Health