Clinical trials: Aggression
Dementia, Aggression
Preventing Aggressive Behavior in Demented Patients
The purpose of this study is to develop and pilot test and non-pharmacological intervention designed to prevent the occurence of aggression in persons with dementia.
- Trial name
- PAVeD (NCT00622128)
- Testing
- Preventing Aggressive Behavior in Demented Patients
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- US Department of Veterans Affairs
Substance Use, Deliberate Self-harm
Evaluation of a Brief Surf the Urge Intervention
The purpose of this study is to evaluate the effectiveness of a brief "Surf the Urge" intervention to reduce adolescent and young adult (i.e., 14 to 24 years old) urge-related behaviors.
- Conditions
- Substance Use, Deliberate Self-harm, Trichotillomania, Aggression
- Trial name
- SUBMI (NCT02771886)
- Testing
- Surf the Urge
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- Kimberly N Schubert
Leukemia, Lymphoma
Combination Chemotherapy Plus Infusion of White Blood Cells in Treating Patients With Hematologic Cancer
RATIONALE: Drugs used in chemotherapy use different ways to stop cancer cells from dividing so they stop growing or die. Combining more than one drug may kill more cancer cells.
- Conditions
- Leukemia, Lymphoma, Myelodysplastic Syndromes, Myelodysplastic/Myeloproliferative Diseases
- Trial name
- NCT00003243
- Testing
- aldesleukin, filgrastim, therapeutic allogeneic lymphocytes
- Where
- United States
- Sponsor
- Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
Lymphoma, B-Cell
Phase I Master Protocol of Novel Combination Therapy for Patients With Relapsed or Refractory Aggressive B-Cell Lymphoma
The purpose of this study is to find the highest dose of a new drug, in combination with standard drugs, which can be tolerated without causing very severe side effects.
- Trial name
- NCT04161248
- Testing
- Venetoclax, Rituximab Injection, Rituximab SC
- Where
- 4 sites in Canada
- Volunteers
- 40 people
- Sponsor
- Canadian Cancer Trials Group
Stress, Health Promotion
The Effects of Pythagorean Self-Awareness Intervention on Young Adolescents in Primary School-Α One Arm Clinical Trial
In this one arm clinical trial, students of the 6th grade in a primary school participated in the PSAI for 8 weeks. Self-report questionnaires and hair cortisol concentrations were used for the evaluation of the aforementioned…
- Conditions
- Stress, Health Promotion, Adolescence
- Trial name
- NCT04824326
- Testing
- PSAI-CA
- Where
- Greece
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- National and Kapodistrian University of Athens
Passive-Aggressive Personality Disorder
Use of Biofeedback and Virtual Reality as Facilitators of Emotional Recognition in the Treatment of Aggressive Outbursts
The methodology will be applied for the treatment of aggressive episodes. Many people show this kind of behavior associated with several psychological disorders like austistic spectrum disorder (ASD).
- Trial name
- BReTIA (NCT05748808)
- Testing
- Use of biofeedback and virtual reality in the treatment of aggressive outbursts
- Where
- Spain
- Volunteers
- 60 people
- Sponsor
- University of Seville
Aggressive Periodontitis
Gingival Crevicular Fluid Levels Of Monocyte Chemoattractant Protein-1
The aim of this study is to estimate GCF MCP-1 levels of healthy and Aggressive periodontitis (AgP) subjects and to compare MCP-1 levels between Localized AgP (LAgP) and Generalized AgP (GAgP) to establish its predictive…
- Trial name
- MCP-1 (NCT02927704)
- Testing
- Gingival crevicular fluid (GCF) sample
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Abant Izzet Baysal University
Attention Deficit Disorder With Hyperactivity, Conduct Disorder
Medication Strategies for Treating Aggressive Behavior in Youth With Attention Deficit Hyperactivity Disorder
This study will assess whether adding a mood stabilizer, divalproex sodium, to stimulant treatment is more effective than stimulant treatment alone in reducing aggressive behavior among children with attention deficit…
- Conditions
- Attention Deficit Disorder With Hyperactivity, Conduct Disorder, Oppositional Defiant Disorder
- Trial name
- NCT00228046
- Testing
- Divalproex Sodium, Methylphenidate, Dextroamphetamine
- Where
- 2 sites in United States
- Volunteers
- 40 people
- Sponsor
- Stony Brook University
Aggressive B-Cell Non-Hodgkin Lymphoma
A Study on Fractionated Rituximab to Avoid Lysis Syndrome in Aggressive B-Lymphoma
Tumour lysis syndrome (TLS) occurs as a consequence of the rapid destruction of malignant cells, spontaneously and/or in response to cytotoxic agents and immunotherapies.
- Trial name
- FRILLY (NCT05840289)
- Testing
- fractionated first dose rituximab
- Where
- Switzerland
- Volunteers
- 94 people
- Sponsor
- University Hospital, Geneva
Problem Behavior, Aggression
Basic and Applied Research on Extinction Bursts
Although highly effective, treatments like FCT include extinction, which can have adverse side effects. The extinction burst, an increase in the frequency or intensity of destructive behavior at the start of treatment, is the…
- Conditions
- Problem Behavior, Aggression, Self Injury
- Trial name
- NCT05925101
- Testing
- Extinction-only condition, Rate-drop condition, Rate-hold condition
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Rutgers, The State University of New Jersey
Prader-Willi Syndrome, Aggression
Guanfacine Extended Release for the Reduction of Aggression and Self-injurious Behavior Associated With Prader-Willi Syndrome
This is a placebo-controlled clinical trial to assess whether Guanfacine Extended Release (GXR) reduces aggression and self injurious behavior in individuals with Prader Willi Syndrome (PWS).
- Conditions
- Prader-Willi Syndrome, Aggression, Self-Injurious Behavior, Pathologic Processes
- Trial name
- PWS-GXR (NCT05657860)
- Testing
- Guanfacine Extended Release
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Maimonides Medical Center
Psychiatric &or Mood Disorder
Effect of Massage Therapy on Aggression in a Psychiatric Inpatient Unit
The purpose of this study is to investigate whether relaxation massage therapy is effective in reducing the levels of arousal and aggression on a young adult inpatient unit.
- Trial name
- NCT00421070
- Testing
- Massage therapy
- Where
- Australia
- Volunteers
- 47 people
- Sponsor
- Melbourne Health
Prader-Willi Syndrome
Dose Clinical Trial of Guanfacine Extended Release for the Reduction of Aggression and Self-injuries Behavior Associated With Prader-Willi Syndrome
This is a placebo-controlled clinical trial to assess the utility of Guanfacine Extended Release (GXR) in the management of patients with Prader Willi Syndrome (PWS) who have significant aggression or self-injury.
- Trial name
- NCT04066088
- Testing
- Guanfacine extended release (GXR)
- Where
- United States
- Sponsor
- NYU Langone Health