Clinical trials: Aggression
Aggressive B-Cell Non-Hodgkin Lymphoma
A Study on Fractionated Rituximab to Avoid Lysis Syndrome in Aggressive B-Lymphoma
Tumour lysis syndrome (TLS) occurs as a consequence of the rapid destruction of malignant cells, spontaneously and/or in response to cytotoxic agents and immunotherapies.
- Trial name
- FRILLY (NCT05840289)
- Testing
- fractionated first dose rituximab
- Where
- Switzerland
- Volunteers
- 94 people
- Sponsor
- University Hospital, Geneva
Diffuse Large B-cell Lymphoma and Aggressive B-cell Lymphomas
Tumour Immune and Ki-67 Scoring Methods as Prognostic Biomarkers in Diffuse Large B-cell Lymphoma and Aggressive B-cell Lymphomas
Diffuse large B-cell lymphoma (DLBCL) is the most common aggressive non-Hodgkin lymphoma with heterogeneity in its clinical presentations, biological behaviour and response to therapy (1-4).
- Trial name
- NCT07804173
- Where
- Egypt
- Volunteers
- 70 people
- Sponsor
- Sohag University
Aggressive, Defiant Disorder, Oppositional
Task-Based Grounding Program
The purpose of this study is to improve the availability of brief interventions to help children with defiant, aggressive and disruptive behaviors by creating a brief scalable intervention for parents delivered via telehealth.
- Conditions
- Aggressive, Defiant Disorder, Oppositional, Attention Deficit Hyperactivity Disorder
- Trial name
- NCT04648553
- Testing
- Task-Based Grounding, Connected Care (Enhanced Treatment as usual)
- Where
- United States
- Volunteers
- 28 people
- Sponsor
- Dartmouth-Hitchcock Medical Center
Aggression
An Evaluation of an Integrated Approach to Prevention and Early Intervention in the Elementary School Years
In this study, the investigators propose to examine whether the combination of a universal, elementary school-based preventive intervention with an indicated preventive and treatment intervention would yield greater impact on…
- Trial name
- P2P+IY (NCT03132805)
- Testing
- PATHS to PAX, PATHS to PAX and the Incredible Years
- Where
- United States
- Volunteers
- 5,233 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins Bloomberg School of Public Health
Bullying of Child, Bullying Victimisation
REThink for Mental Health of the Youths in Romania
In order to test the effect of the intervention, a multi-center randomized control trial (RCT) will be conducted to test the efficacy of the REThink interventions on improving bullying (both victimization and aggression) and…
- Conditions
- Bullying of Child, Bullying Victimisation, Bullying
- Trial name
- REThink (NCT06646159)
- Testing
- REThink Intervention
- Where
- Romania
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Babes-Bolyai University
Respiratory Failure, Volume Overload
Stop Hypernatremia, Use Metolazone, for Aggressive, Controlled, Effective Diuresis
Patients who are on mechanical ventilation in an intensive care unit often require diursis as part of their pre-extubation regimen. The drug of choice for diuresis has traditionally been furosemide.
- Conditions
- Respiratory Failure, Volume Overload, Hypernatremia
- Trial name
- SHUM (NCT01617798)
- Testing
- Supplemental metolazone diuresis
- Where
- United States
- Sponsor
- Oregon Health and Science University
Depression
The Relationships of Cyber-bullying and Bullying With Mental Health Among Taiwanese Adolescents
Background and significance: Though the problem of bullying among adolescents is evidently increasing and of a serious social concern, it is often undetected until serious outcomes have surfaced.
- Trial name
- NCT02860832
- Where
- Taiwan
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Lung Neoplasms, Progression
Tumor Cell Plasticity and Aggressiveness in Human Non-small Cell Lung Cancer
Tumor cell plasticity (TCP) is a conubium of processes which lead to re-activation of developmental programs correlating with epithelial-to-mesenchymal transition, and ultimately leading to acquisition of stem cell properties and…
- Trial name
- NCT06409416
- Testing
- Analysis of diagnostic biomarkers
- Volunteers
- 20 people
- Sponsor
- Casa Sollievo della Sofferenza IRCCS
Aggression Childhood, Teen Dating Violence
Trauma-Informed Peer Aggression and Dating Violence Prevention for Preteens Receiving Intensive Mental Health Services
The goal of this clinical trial is to learn if this intervention (Social Skills, Problem Solving, emotion Regulation, and psycho-Education on Trauma: A Trauma-Informed Peer Aggression and Teen Dating Violence Prevention Program…
- Trial name
- SPARE (NCT06769282)
- Testing
- Experimental: Intervention (SPARE) plus Treatment as Usual, Treatment as Usual (TAU)
- Where
- United States
- Volunteers
- 88 people
- Sponsor
- Rhode Island Hospital
PTSD, Depression
Trauma and Truth Interventions (NET) Versus Conflict Resolution and Social Skills Trainings for Vulnerable Youths in Northern Uganda
More than 300,000 children are fighting in armed conflicts all over the world. In Uganda an estimated number of 25,000 children have been abducted and forced to fight or work as porters and sex slaves on the side of the rebels…
- Conditions
- PTSD, Depression, Aggression
- Trial name
- NCT00893750
- Testing
- NET Truth Education, Conflict Resolution and Social Competence Skills, Traditional Ways of Coping
- Where
- Uganda
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- University of Konstanz
Oppositional Defiant Disorder
Treatment of Children With Peer Related Aggressive Behavior (ScouT)
The efficacy of the computer based Treatment Program for Children with Aggressive Behaviour (Soziales computerunterstütztes Training für Kinder mit aggressivem Verhalten, ScouT) which is a child focused social competence training…
- Trial name
- NCT02143427
- Testing
- Social Skills Training, Treatment Program with techniques to activate resources
- Where
- Germany
- Volunteers
- 140 people
- Sponsor
- University of Cologne
Aggressive Fibromatosis
National Clinical-biological Prospective Cohort of Incident Cases of Aggressive Fibromatosis (ALTITUDES)
The purpose of this study is to constitute the French largest Aggressive fibromatosis cohort.
- Trial name
- ALTITUDES (NCT02867033)
- Testing
- biopsy, biobank constitution, Coloscopy
- Where
- 39 sites in France
- Volunteers
- 628 people
- Sponsor
- Centre Oscar Lambret
Generalized Aggressive Periodontitis
Metagenomic and Immune-inflammatory Analysis of Individuals With Generalized Aggressive Periodontitis and Their Descendants.
Generalized aggressive periodontitis (GAgP) is a multifactorial disease related to several aspects that influence its installation and progression.
- Trial name
- NCT03933514
- Testing
- Plaque control
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- University of Campinas, Brazil
Thyroid Cancer
This Study is Mainly About Finding Incidence Among Other Factors of Thyroid Cancer in Patient with Benign Disease As MNG to Early Discover of the Malignancy to Save the Patient from Aggressive Procedure
The purpose of the present study was to evaluate the prevalence of thyroid cancer in patients who had thyroidectomy for MNG, and analyze patient-related parameters to identify type and risk factors associated with incidental…
- Trial name
- NCT06730971
- Testing
- Total thyroidectomy
- Volunteers
- 300 people
- Sponsor
- Asmaa Mohamed Emam
Aggression, Antisocial Behavior
Omega-3 Supplementation and Behavior Problems
The objectives of this project are as follows: 1. To assess whether omega-3 dietary supplementation for six months can reduce externalizing behavior problems (antisocial and aggressive behavior) in schoolchildren aged 8 to 18…
- Conditions
- Aggression, Antisocial Behavior, Antisocial Personality
- Trial name
- NCT02334098
- Testing
- Omega-3 supplemented drink, Smartfish
- Where
- China
- Volunteers
- 324 people, healthy volunteers welcome
- Sponsor
- Dr. Annis Fung
Social Competence, Bullying
Effects of ACT OUT! Social Issue Theater on Youth and Adolescents
The ACT OUT! Trial is designed as a proof-of-concept, cluster, randomized, superiority trial with two parallel groups. Although the unit of measurement is student, the unit of randomization is classroom, stratified by school.
- Trial name
- NCT04097496
- Testing
- Act Out! Intervention
- Where
- United States
- Volunteers
- 1,537 people, healthy volunteers welcome
- Sponsor
- Indiana University
Aggression
Risperidone Augmentation for Treatment-Resistant Aggression in ADHD
Primary objectives: 1. To assess the short-term efficacy of risperidone augmentation for treatment-resistant aggression in children with ADHD. 2.
- Trial name
- NCT00297739
- Testing
- Risperidone
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Armenteros, Jorge L., M.D., P.A.
Bullying
Bullying Experiences Among Alexandria Faculty of Medicine Students
A cross-sectional study was conducted at Faculty of Medicine, Alexandria to study the prevalence, types and consequences of bullying among medical students. An online survey was distributed among medical students.
- Trial name
- NCT06517329
- Where
- Egypt
- Volunteers
- 565 people
- Sponsor
- Alexandria University
Child Development Disorders, Pervasive
Randomized Trial of Parent Training for Young Children With Autism
The purpose of this 24 week study is to determine whether a new Parent Training program is effective in reducing disruptive behaviors in young children with pervasive developmental disorders.
- Trial name
- RUBI (NCT01233414)
- Testing
- Parent Training, Psychoeducational Program
- Where
- 6 sites in United States
- Volunteers
- 180 people
- Sponsor
- Yale University
Periodontitis, Juvenile
Chairside Mouthrinse Test and Cost Effectiveness
The aim is to study whether participants at risk could be identified using an aMMP-8 chairside mouth rinse test and to study if oral health and health behaviour is linked to the test result in Finnish adolescents.
- Trial name
- JuvePar (NCT04139863)
- Testing
- aMMP-8 chairside test
- Where
- Finland
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of Helsinki