Clinical trials: Aging
Aging
Epigenetics in the Aging Process
This study will examine the role of epigenetics (heritable changes in gene function that occur without a change in DNA sequence) in the aging process.
- Trial name
- NCT00242255
- Where
- 4 sites in United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Inactivity, Physical, Aging
Oral 'Breath Test' to Measure Anabolic Sensitivity to a Protein Meal Across the Age and Physical Activity Spectrum
The purpose of this study is to determine how anabolic sensitivity, in response to the ingestion of a liquid protein meal, differs across the lifespan, between biological sexes, and with varying physical activity levels.
- Conditions
- Inactivity, Physical, Aging, Healthy Aging, Growth & Development
- Trial name
- NFRF (NCT06744491)
- Where
- Canada
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Caesarean Delivery
Regenerative Effects of Birth Material Derived Extracellular Vesicles
Stem cells offer great hope for a wide range of disorders, including age-related brain disease such as dementia. Mesenchymal stem cells (MSCs) are special types of adult stem cells found in various tissues like the umbilical…
- Trial name
- ReGAIN (NCT06866184)
- Where
- United Kingdom
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Aberdeen
Persistent COVID-19, Quality of Life
Vascular Structure, Vascular Function and Vascular Aging in Adults Diagnosed With Persistent COVID
The ICOPER study aims to analyze the structure, vascular function, vascular aging and determining factors in 300 adults diagnosed with Persistent Covid in the field of Primary Health Care.
- Conditions
- Persistent COVID-19, Quality of Life, Lifestyles, Arterial Stiffness
- Trial name
- ICOPER (NCT05819840)
- Where
- Spain
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Fundacion para la Investigacion y Formacion en Ciencias de la Salud
Muskuloskeletal Diseases
Approaches to Chiropractic Care in Aging Patients
The goal of this observational study is to understand how chiropractors adjust their therapeutic approaches based on their beliefs, the patient's age, and patient-specific characteristics, with a particular focus on aging…
- Trial name
- NCT07023809
- Where
- Canada
- Volunteers
- 12 people
- Sponsor
- Université du Québec à Trois-Rivières
Ethics, Aging
The Effect of Aging Simulation Suits on Nursing Students' Attitudes Toward Older Adults and Their Levels of Compassion
With the increasing elderly population, nursing students' attitudes toward older adults and their levels of compassion competence have become increasingly important.
- Conditions
- Ethics, Aging, Compassion
- Trial name
- NCT07547475
- Testing
- aging simulation suit on nursing students', aging simulation suit on nursing students
- Where
- Cyprus
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- Eastern Mediterranean University
Cockayne Syndrome
Observational Study to Assess Natural History in Cockayne Syndrome Patients
This is an Observational Study of children under the age of 11 diagnosed with Cockayne Syndrome to assess the natural progression of Cockayne Syndrome disease, with special attention to hearing and physical changes in length or…
- Trial name
- NCT00985413
- Where
- 4 sites in United States, France and 1 more
- Volunteers
- 40 people
- Sponsor
- DNage B.V.
Aging
Large-scale Multi-omics Analysis of Cerebrospinal Fluid
The aim of this study is to explore the role of cerebrospinal fluid (CSF) biomarkers in aging and neurodegenerative diseases.
- Trial name
- NCT06636201
- Where
- China
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Sarcopenia
Sarcopenia and Aging
Objective: Evaluate the muscular strength in the ageing process and identify the changes between the abdominal muscles, upper and louver edges.
- Trial name
- NCT00907010
- Volunteers
- 48 people
- Sponsor
- Universidade de Franca
Work Stress, Sleep Disturbance
The Use of Worktime Planning Tools in the Finnish Public Sector. A Quasi-experimental Study (PLANTOOLS)
This study aims to investigate whether use of interactive worktime planning tools that support work-time control (possibilities to influence individual shift rosters, i.e., participatory rostering) and guide for health-supporting…
- Trial name
- PLANTOOLS (NCT02775331)
- Testing
- Shift planning with self-rostering and shift ergonomics, Shift planning with shift ergonomics
- Volunteers
- 9,000 people, healthy volunteers welcome
- Sponsor
- Finnish Institute of Occupational Health
Frailty, Emergencies
ER2 Frailty Levels and Incident Adverse Health Events in Older Community Dwellers
Older adults' health and functional status are heterogeneous because of the various cumulative effects of chronic diseases and physiologic decline, contributing to a vicious cycle of increased frailty 1-4.
- Conditions
- Frailty, Emergencies, Aging
- Trial name
- NCT04431986
- Testing
- No intervention: secondary use of a database
- Volunteers
- 1,741 people, healthy volunteers welcome
- Sponsor
- Jewish General Hospital
Ovarian Aging, Adverse Pregnancy Outcomes
The Bone and hEArt Health Consequences of Ovarian agiNg (BEACON) Study
Ovarian aging is a major driver of a woman's long-term health and disease risk. In particular, the rapid decline in the ovarian reserve that occurs with the menopause transition is linked to a striking increase in the risk for…
- Trial name
- BEACON (NCT07621965)
- Volunteers
- 655 people
- Sponsor
- Indiana University
Frailty, Physical Disability
Vitamin D and Calcium Supplementation at Danish Nursing Homes
Nursing home residents are in high risk of vitamin D deficiency, which negatively affects bone health. Vitamin D and calcium supplements have shown to increase bone density and reduce fracture risk and may affect daily physical…
- Conditions
- Frailty, Physical Disability, Aging, Muscle Weakness
- Trial name
- NCT04956705
- Testing
- Vitamin D and calcium
- Where
- 2 sites in Denmark
- Volunteers
- 109 people, healthy volunteers welcome
- Sponsor
- University College Copenhagen
Surgery, Aging
Preparing Older Adults for Major Surgery With Preoperative Comprehensive Geriatric Assessments
The researchers will conduct observations, interviews, and focus groups with clinicians, staff and patients of the Perioperative Optimization of Senior Health (POSH) clinic, which conducts preoperative comprehensive geriatric…
- Conditions
- Surgery, Aging, Health Care Utilization, Frailty
- Trial name
- NCT06184919
- Testing
- Process Mapping: Observations, Process Mapping: Interviews, Process Mapping: Focus Group
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of Wisconsin, Madison
Refractive Error
Ocular Comfort and the "Aging" Lens (ERBIUM)
The purpose of this trial was to evaluate the factors affecting comfortable contact lens wear and how those factors affect contact lens replacement frequency.
- Trial name
- NCT01198600
- Testing
- Habitual contact lens, Lotrafilcon B contact lens, Contact lens cleaning and disinfecting system (ClearCare)
- Where
- Canada
- Volunteers
- 78 people
- Sponsor
- CIBA VISION
Hypophosphatemia, Rickets
The Impact of Phosphate Metabolism on Healthy Aging
Determine the association between duration and dose of chronic conventional therapy with Pi and renal (nephrocalcinosis/nephrolithiasis), vascular (endothelial function), and cardiovascular function (echo- cardiography) in…
- Conditions
- Hypophosphatemia, Rickets, Hypercalciuria, XLH
- Trial name
- NCT03771105
- Testing
- phosphate
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Yale University
Fall Prevention in Healthy Aging
Bridging Generations: Educating Children on Dementia and Fall Prevention Through Animation
A retrospective data review was conducted on a case-control trial involving 60 children (29 boys, 31 girls) as part of a public education initiative hosted on the web-based platform "Hand in Hand Across Barriers - Public…
- Trial name
- fall (NCT07000370)
- Where
- United Kingdom
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Northumbria University
Dysbiosis, Inflammation Gum
Microbiome Alterations With Xylitol (MAX) in Pregnancy
The purpose of this study is to understand if chewing xylitol-gum initiated before 20 weeks of pregnancy and continued until delivery affects the bacteria that are found in the oral and vaginal cavities, signs of inflammation…
- Conditions
- Dysbiosis, Inflammation Gum, Placenta-mediated Pregnancy Complications, Microbioata
- Trial name
- MAX (NCT06329596)
- Testing
- Xylitol gum, Sorbitol gum
- Where
- Malawi
- Volunteers
- 80 people
- Sponsor
- Baylor College of Medicine
Progeria
Clinical Studies of Progeria
This study will examine children with Hutchinson-Gilford Progeria syndrome, a genetic disease that causes many changes to the body over time, including heart disease, bone changes, hair loss, and joint and skin changes.
- Trial name
- NCT00094393
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- National Human Genome Research Institute (NHGRI)
Aging, Ageism
Intergroup Contact Intervention for Nursing Undergraduates to Improve Aging Stereotype
This study aimed to investigate the effects of intergroup contact training on the levels of aging stereotypes, intergroup anxiety, and willingness to engage in geriatric nursing work among undergraduate nursing students.
- Trial name
- NCT06615219
- Testing
- Intergroup contact training, Regular course training only
- Where
- China
- Volunteers
- 126 people
- Sponsor
- Huzhou University