Clinical trials: Aging, completed
Photosensitivity Disorders
Skin Aging in Renal Transplant Patients
Determination of collagen, pigment and haemoglobin content of sun exposed and sun protected skin by Siascopy. Immunocompromised patients (for more than seven years) compared to immunocompetent patients.
- Trial name
- NCT01776983
- Testing
- Photosensitivity under the influence of immunocomp
- Where
- Switzerland
- Volunteers
- 100 people
- Sponsor
- University of Zurich
Hypertension, Hormone Disturbance
12 Weeks of Resistance Band Exercise Impacts on Adiposity, Hormones, and Blood Pressure in Postmenopausal Women
The purpose of this study was to examine the impacts of a 12-week resistance band exercise program on body composition, aging-related hormones, and blood pressure in postmenopausal women with stage 1 hypertension.
- Conditions
- Hypertension, Hormone Disturbance, Adiposity
- Trial name
- NCT03919201
- Testing
- Resistance band exercise intervention, No exercise intervention group
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Pusan National University
Malnutrition
Assessment of Food Practices by Residents in Nursing Homes
Nutrition is an essential component of health and a key determinant of aging and quality of life of individuals. Malnutrition in the elderly is now recognized as a public health problem affecting nearly half of residents in…
- Trial name
- ARC2 (NCT02626078)
- Testing
- observation and interview of residents
- Where
- 8 sites in France
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Hospices Civils de Lyon
Cataract
Dynamic Light Scattering for Studying Lens Aging and Cataract Formation
This study will use dynamic light scattering (DLS) technology to study normal lens aging and early cataract formation. Cataract is a clouding of the lens that interferes with the passage of light to the retina, impairing visual…
- Trial name
- NCT00081991
- Where
- United States
- Volunteers
- 267 people, healthy volunteers welcome
- Sponsor
- National Eye Institute (NEI)
Cardiovascular Disease, Skin Health
Effects of Anthocyanin on Skin Health and Markers of Cardiovascular Disease Risk
The purpose of this study is to determine whether short-term exposure to a compound found in some fruits and vegetables (anthocyanin), is effective in improving skin health and reducing the levels of various markers of…
- Conditions
- Cardiovascular Disease, Skin Health, Postmenopause
- Trial name
- NCT00574574
- Testing
- anthocyanin
- Where
- United Kingdom
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- University of East Anglia
Frailty, Physical Disability
Vitamin D and Calcium Supplementation at Danish Nursing Homes
Nursing home residents are in high risk of vitamin D deficiency, which negatively affects bone health. Vitamin D and calcium supplements have shown to increase bone density and reduce fracture risk and may affect daily physical…
- Conditions
- Frailty, Physical Disability, Aging, Muscle Weakness
- Trial name
- NCT04956705
- Testing
- Vitamin D and calcium
- Where
- 2 sites in Denmark
- Volunteers
- 109 people, healthy volunteers welcome
- Sponsor
- University College Copenhagen
Atherosclerosis, Life Style
Effect of a Cardiovascular Health Promotion Program in Youth - The Tyrolean Early Vascular Ageing-study
Atherosclerosis - the main cause of cardiovascular diseases - starts already in childhood. The Tyrolean Early Vascular Ageing-study aims to improve the vascular health of Tyrolean adolescents by a multi-layer intervention program.
- Trial name
- EVA-Tyrol (NCT03929692)
- Testing
- Multi-layer health promotion program, Standard health education
- Where
- 2 sites in Austria, Italy
- Volunteers
- 2,102 people, healthy volunteers welcome
- Sponsor
- Medical University Innsbruck
Osteopenia, Arterial Hypertension
Comparative Effects of Moxonidine on Bone Metabolism, Vascular and Cellular Aging in Hypertensive Postmenopausal Women
This study evaluates the effect of moxonidine versus bisoprolol on collagen type 1 C-telopeptide in postmenopausal female patients with arterial hypertension and osteopenia.
- Trial name
- COMPASS (NCT02355821)
- Testing
- Moxonidine, Bisoprolol
- Where
- Russia
- Volunteers
- 114 people
- Sponsor
- National Research Center for Preventive Medicine
Intergenerational Relations, Aging Well
Cyber School for Grandparents: an Intergenerational Educational Program
Social participation and social relationships are relevant aspects of older adult's psychosocial well-being. In this regard, specific interest is devoted to Information and Communication Technologies (ICT) which enable to connect…
- Trial name
- NCT05135819
- Testing
- Cyber School for Grandparents
- Where
- Italy
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Antonio Guaita, MD
Aging
Implementing Shared Decision Making in Interprofessional Home Care Teams
This study will train health providers in home care teams across Quebec in shared decision making about the decision to stay at home or move to another location. This decision is one of the toughest for older Canadians.
- Trial name
- IPSDM-SW (NCT02592525)
- Testing
- IP-SDM training for health professionals
- Where
- Canada
- Volunteers
- 653 people, healthy volunteers welcome
- Sponsor
- CHU de Quebec-Universite Laval
Progeria
Clinical Studies of Progeria
This study will examine children with Hutchinson-Gilford Progeria syndrome, a genetic disease that causes many changes to the body over time, including heart disease, bone changes, hair loss, and joint and skin changes.
- Trial name
- NCT00094393
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- National Human Genome Research Institute (NHGRI)
Cockayne Syndrome
Pharmacokinetics and Safety Study of Single and Multiple Oral Doses Prodarsan™ in Patients With Cockayne Syndrome
This study is to compare the exposure of orally administered Prodarsan to the intravenous dosed Osmitrol (10% solution) in Cockayne Syndrome (CS) patients.
- Trial name
- NCT01142154
- Testing
- Prodarsan
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- DNage B.V.
Heart Disease, Physical Frailty
Genetics and Epidemiology of Aging Associated Conditions in the Sardinian Population
Background: The island of Sardinia, an Italian region, has a population that is highly interrelated. Researchers have developed the SardiNIA longitudinal study to examine the possible genetic factors that predispose individuals…
- Conditions
- Heart Disease, Physical Frailty, Exaggerated Personality Traits
- Trial name
- NCT00182949
- Where
- Italy
- Volunteers
- 6,926 people, healthy volunteers welcome
- Sponsor
- National Institute on Aging (NIA)
Virtual Reality, Bucket List
Assessing the Feasibility of Using Virtual Reality Experiences in Older Adults
To assess the feasibility of using computer-generated VR (CG-VR) and film-based VR (FB-VR) in seriously ill older adults
- Conditions
- Virtual Reality, Bucket List, Serious Illness, Aging
- Trial name
- NCT07580352
- Testing
- Feasibility of using VR
- Where
- United States
- Volunteers
- 52 people
- Sponsor
- Stanford University
Alzheimer's Disease, Aging
Memory Aid for Informed Consent in Alzheimer's Research
The purpose of this trial is to test whether a memory and organizational aid in the form of a document that summarizes and simplifies a study's key points can improve the decision-making abilities and competency of mild to early…
- Trial name
- NCT00105612
- Testing
- Memory and Organizational Aid, Standard Informed Consent Process
- Where
- United States
- Volunteers
- 110 people
- Sponsor
- National Institute on Aging (NIA)
Health Behavior, Ageing
Supporting Healthy Aging by Peer Education and Support
Canadians are living longer than ever before. However, many in our society age with long term chronic medical conditions which have a major impact on their need for healthcare, their quality of life and well-being.
- Trial name
- SHAPES (NCT02745275)
- Testing
- Peer-led Health Education
- Where
- Canada
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- University of Alberta
Cardiovascular Diseases, Heart Diseases
Epidemiology of Depression and Heart Failure in Aging
To understand how depression leads to congestive heart failure (CHF) in older adults.
- Conditions
- Cardiovascular Diseases, Heart Diseases, Heart Failure, Heart Failure, Congestive
- Trial name
- NCT00241761
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Glaucoma
Glaucoma Within Northern Ireland Cohort for the Longitudinal Study of Ageing
Glaucoma is the leading cause of irreversible blindness worldwide. It is caused by damage to the optic nerve between the back of the eye and the brain leading to progressive blindness.
- Trial name
- GwNICOLA (NCT03109665)
- Testing
- SD-OCT Angiography, SD-OCT
- Where
- United Kingdom
- Volunteers
- 129 people
- Sponsor
- Queen's University, Belfast
Cancer, Malignant Neoplasm
Measuring Changes in Body Composition and Physical Function in Patients With Childhood Cancers
The primary objective of this study is to evaluate the feasibility and acceptability of obtaining repeated measurements of lean muscle mass, physical function, and biological aging in children receiving active cancer therapy.
- Trial name
- NCT05823740
- Testing
- Bioelectrical impedance Analysis (BIA), D3-Creatine Dilution (D3Cr), 6-Minute Walk Test (6MWT)
- Where
- United States
- Volunteers
- 28 people
- Sponsor
- UNC Lineberger Comprehensive Cancer Center
Colorectal Cancer
The Biomarkers Of RIsk of Colorectal Cancer (BORICC) Follow-Up (BFU) Study
Worldwide, colorectal cancer is the 3rd most common cancer; risk increases with age and is modified by lifestyle factors notably diet, physical activity and obesity.
- Trial name
- BFU (NCT04005742)
- Where
- United Kingdom
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- Newcastle University