Clinical trials: Albumins
Hemophilia B
Recombinant Fusion Protein Linking Coagulation Factor IX With Albumin (rIX-FP) in Chinese Subjects With Hemophilia B Previously Treated With FIX Therapy
This study will investigate the pharmacokinetics (PK), efficacy, and safety of rIX-FP for the routine prophylaxis of bleeding episodes in male Chinese previously treated patients (PTPs) with hemophilia B (FIX activity of ≤ 2%).
- Trial name
- NCT06399289
- Testing
- Recombinant fusion protein linking coagulation factor IX with albumin (rIX-FP)
- Where
- 7 sites in China
- Volunteers
- 23 people
- Sponsor
- CSL Behring
Ridge Preservation
E-PRF vs Collagen Membranes in Ridge Preservation
Dental implants are often considered the gold standard to replace missing teeth. Having success with dental implants depends on the hard tissue and soft tissue remaining after tooth extractions.
- Trial name
- NCT07281053
- Testing
- Barrier membrane for ridge preservation
- Where
- United States
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- Center for Advanced Rejuvenation and Esthetics
Burns
Albumin Use in Burn Patients
This is a study of why and how physicians use albumin during the first 72 hours after a burn injury.
- Trial name
- NCT00609414
- Where
- 12 sites in United States, Canada
- Volunteers
- 460 people
- Sponsor
- University of North Carolina, Chapel Hill
Gastric Cancer
Neoadjuvant Chomotherapy With Paclitaxel-albumin and S-1 for Advanced Gastric Cancer
This is a interventional clinical trial to assess the efficacy and safety of combinational therapy of paclitaxel-albumin and S-1 for the neoadjuvant chemotherapy of advanced gastric cancer.
- Trial name
- NCT04258657
- Testing
- paclitaxel-albumin and S-1
- Where
- China
- Volunteers
- 20 people
- Sponsor
- Beijing Friendship Hospital
Hemophilia A
Study Evaluating On-Demand Treatment Of Xyntha In Chinese Subjects
This study will evaluate the safety and efficacy of on-demand treatment with Xyntha in Chinese hemophilia A subjects.
- Trial name
- NCT00868530
- Testing
- Xyntha
- Where
- 6 sites in China
- Volunteers
- 53 people
- Sponsor
- Pfizer
Chicken-pox Illness (Varicella Virus Disease), Chickenpox
A Safety and Immune Study of 2 Types of GlaxoSmithKline's Varicella Vaccines Given as a 2-doses Course to Healthy Children 12-23 Months of Age.
The purpose of this study is to evaluate the safety and immunogenicity of 2 formulations of GSK Biologicals' varicella vaccines given as a 2-dose course in the second year of life.
- Trial name
- NCT02570126
- Testing
- Varilrix HSA-free, Varilrix™
- Where
- 23 sites in Estonia, Germany and 3 more
- Volunteers
- 1,236 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Acute Kidney Injury, Pediatric Cardiac Surgery
The Effect of Preoperative Albumin Administration on Postoperative Acute Kidney Injury in Pediatric Patients With Hypoalbuminemia Undergoing Cardiac Surgery
The study aims to evaluate whether preoperative albumin supplementation in pediatric patients with hypoalbuminemia undergoing cardiac surgery can reduce inflammatory responses and prevent acute kidney injury (AKI) following…
- Trial name
- NCT06710353
- Testing
- Albumin solution, Crystalloid solutions
- Where
- South Korea
- Volunteers
- 190 people
- Sponsor
- Seoul National University Hospital
Rupture, Spontaneous, Rupture Liver
A Comparison Between Child-Pugh and Albumin-Bilirubin Scores
To compare Child-Pugh and Albumin-Bilirubin scores in patients with spontaneous rupture of hepatocellular carcinoma
- Conditions
- Rupture, Spontaneous, Rupture Liver, Hepatocellular Carcinoma, Hepatic Impairment
- Trial name
- NCT03534843
- Testing
- Liver resection, Transcatheter arterial embolization
- Volunteers
- 230 people
- Sponsor
- Huazhong University of Science and Technology
Pancreaticoduodenectomy, Pancreatic Fistula
Intravenous Human Albumin In Improving Pancreaticoduodenectomy Outcomes
Pancreaticoduodenectomy (PD), more commonly known as Whipple's surgery is the mainstay treatment for pancreatic head and periampullary cancer.
- Conditions
- Pancreaticoduodenectomy, Pancreatic Fistula, Delayed Gastric Emptying, Pancreatic Cancer
- Trial name
- NCT04418739
- Testing
- Human albumin
- Where
- Malaysia
- Volunteers
- 122 people, healthy volunteers welcome
- Sponsor
- Universiti Kebangsaan Malaysia Medical Centre
Measles, Mumps
Safety Study of ProQuad® rHA in Infants (V221-037)
Primary objective: To describe the safety profile of a second dose of ProQuad® manufactured with recombinant human albumin (rHA) when administered to children in their second year of life.
- Conditions
- Measles, Mumps, Rubella, Varicella
- Trial name
- NCT00560755
- Testing
- ProQuad®
- Volunteers
- 3,388 people, healthy volunteers welcome
- Sponsor
- Merck Sharp & Dohme LLC
Systemic Lupus Erythematosus
The Predictive and Prognostic Values of the Fibrinogen to Albumin Ratio and C-reactive Protien to Albumin Ratio in Systemic Lupus Erythematosus Patients
The aim of the study was to study the predictive value of FAR and CAR in order to provide a new predictive biomarkers for the disease activity and prognosis.
- Trial name
- NCT06404723
- Testing
- Fibrinogen to albumin Ratio and C-reactive to Albumin Ratio
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Sohag University
Hemoglobins, Albumins
Association Between Preoperative HALP and Immediate Postoperative Outcomes
Multiple inflammation-based prognostic scores have been developed for the prediction of perioperative morbidity and mortality following pancreaticoduodenectomy (PD).
- Conditions
- Hemoglobins, Albumins, Platelets, Lymphocytes
- Trial name
- NCT05506748
- Testing
- pantients undergoing pancreaticoduodenectomy
- Where
- Nepal
- Volunteers
- 22 people
- Sponsor
- Chitwan Medical College
Idiopathic Nephrotic Syndrome (INS)
Comparison of Efficacy and Safety of Albumin Versus Fresh Frozen Plasma in Managing Diuretic Resistant Edema in Children With Idiopathic Nephrotic Syndrome.
Edema is a major component of nephrotic syndrome (NS), defined by Kidney Disease Improving Global Outcomes (KDIGO) guidelines is, urine protein/creatinine ratio ≥ 2 mg/mg, and hypoalbuminemia ≤ 2.5 g/dl).
- Trial name
- ALB-FFP (NCT07685093)
- Testing
- Human Albumin 20%, Fresh Frozen Plasma
- Volunteers
- 56 people
- Sponsor
- Qamar Shafiq
Type 2 DM /Diabetic Nephropathy
CRP to Serum Albumin Ratio in Type 2 DM é Diabetic Nephropathy
we aimed to compare C-reactive protein to serum albumin ( CAR) level of the T2DM patients with DN to those T2DM without DN
- Trial name
- NCT05681286
- Volunteers
- 70 people
- Sponsor
- Assiut University
Very Preterm Infants
Plasma Protein Levels and Very Preterm Birth
The primary aim of this study is to investigate the relationship between early plasma protein levels and hemodynamics in very preterm infants during postnatal transition.
- Trial name
- ProHémie (NCT02007902)
- Testing
- Evaluation of the relationship plasma protein levels - neonatal hemodynamics
- Where
- 2 sites in France
- Volunteers
- 125 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de la Réunion
Hyperbilirubinemia, Neonatal
Role of Serum (B/A) Ratio Compared to (TSB) for Early Prediction of Bilirubin-induced Neurological Dysfunction (BIND).
The aim of this study is to evaluate serum bilirubin/albumin (B/A) ratio compared to total serum bilirubin (TSB) for early prediction of bilirubin-induced neurological dysfunction (BIND).
- Trial name
- NCT06603753
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- alaa aboelhassan mohamed aboelhassan
Extracranial Germ Cell Tumor, Pediatric
Nab-PTX, Ifosfamide and Cisplatin in the Treatment of Pediatric Extracranial Germ Cell Tumor.
The purpose is to evaluate the effectiveness and safety of albumin-bound paclitaxel (nab-PTX), ifosfamide and cisplatin in the treatment of children patients with advanced, recurrent or refractory extracranial germ cell tumor.
- Trial name
- NCT04581265
- Testing
- albumin-bound paclitaxel (nab-PTX), ifosfamide and cisplatin
- Volunteers
- 43 people
- Sponsor
- Sun Yat-sen University
Type 1 Diabetes
PREVENTKD (Prevent Risks by Early interVEntion at Nighttime in Type 1 Diabetes for Kidney Disease)
The purpose of this study is to determine if the early treatment with a blood pressure medication (an ACE Inhibitor) can prevent or delay the development of kidney disease (microalbuminuria) in patients with Type 1 diabetes who…
- Trial name
- PREVENTKD (NCT00729365)
- Testing
- Ramipril
- Where
- 6 sites in United States
- Volunteers
- 65 people
- Sponsor
- Northwestern University
Measles, Mumps
Immunogenicity and Safety of Concomitant Administration of MMR™ rHA and VARIVAX® by Intramuscular Versus Subcutaneous Route (V205C-011)
Primary objective: To compare if, when given concomitantly with VARIVAX® by the same route at 12-18 months of age using separate injection sites, a single dose of M-M-RTMII administered by IM route is as immunogenic as a single…
- Conditions
- Measles, Mumps, Varicella
- Trial name
- NCT00432523
- Testing
- M-M-R™II manufactured with recombinant Human Albumin (rHA) and VARIVAX®
- Where
- 2 sites in France, Germany
- Volunteers
- 752 people, healthy volunteers welcome
- Sponsor
- Merck Sharp & Dohme LLC
Gestational Diabetes Mellitus in Pregnancy
Can Albumin/C-reactive Protein Ratio be Utilized for Predicting Gestational Diabetes Diagnosis or the Adverse Outcomes
This study provides a comprehensive evaluation of the potential utility of the albumin/high-sensitivity C-reactive protein (hsCRP) ratio in diagnosing gestational diabetes mellitus (GDM) and predicting adverse pregnancy outcomes.
- Trial name
- Alb/hsCRP (NCT06761053)
- Testing
- Intervention/Exposure for the GDM Group (Experimental Arm), Intervention/Exposure for the Control Group
- Where
- Turkey (Türkiye)
- Volunteers
- 146 people, healthy volunteers welcome
- Sponsor
- Mustafa Kemalpasa Government Hospital