Clinical trials: Alcohol Drinking
Healthy
Alcohol Metabolism and Disease Risk in Asians
The primary pathway of alcohol metabolism involves two main enzymes, alcohol and aldehyde dehydrogenase. Several genes that encode these enzymes have variants that alter the rate of alcohol metabolism and increase levels of…
- Trial name
- R21AA28365 (NCT04967599)
- Testing
- Phenotype Feedback Intervention, Genotype Feedback Intervention
- Where
- United States
- Volunteers
- 360 people, healthy volunteers welcome
- Sponsor
- University of Southern California
HIV-infection/Aids, Intimate Partner Violence
Improving HIV Care Engagement Among Ugandan Adolescent Girls and Young Women: The Kisoboka Mukwano Intervention
This study will develop and pilot test a couples-based intervention to help adolescent girls and young women living with HIV (WLHIV (15-24 years) living in Uganda access HIV care and improve the outcomes of their HIV treatment by…
- Conditions
- HIV-infection/Aids, Intimate Partner Violence, Domestic Violence, Alcohol Use Disorder
- Trial name
- NCT05947539
- Testing
- Kisoboka Mukwano ("It is possible, my love!") Intervention, Screening and Referral
- Where
- Uganda
- Volunteers
- 80 people
- Sponsor
- Arizona State University
Alcohol Consumption
The Effect of Computerized Alcohol Screening and Brief Intervention (CASI) on Alcohol Consumption in Adolescent Patients in the Emergency Department
The purpose of this research is to examine the effectiveness of the Computerized Alcohol Screening and Brief Intervention (CASI) in adolescent patients in the Emergency Department at the UC Irvine Medical Center.
- Trial name
- CASI (NCT01680627)
- Testing
- CASI
- Where
- United States
- Volunteers
- 235 people
- Sponsor
- University of California, Irvine
Substance Use Disorders, HIV Infections
Development and Evaluation of a Virtual Reality Tool for At-Risk Trauma-Exposed Young People
This is a multi-phased study, funded through a National Institute on Drug Abuse (NIDA) K24 grant that aims to ultimately refine a virtual reality tool through qualitative and quantitative research targeting HIV and substance…
- Trial name
- NCT05816083
- Testing
- Virtual Reality Tool
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Medical University of South Carolina
Alcohol Use Disorder
Enhancing the Effects of Adolescent Alcohol Treatment With Atomoxetine
The primary objectives of this study are twofold. The first primary objective is to evaluate the feasibility, acceptability, and tolerability of atomoxetine (40 mg/day for 3 days then 80 mg/day thereafter) as compared to placebo…
- Trial name
- NCT04565288
- Testing
- Atomoxetine
- Where
- United States
- Volunteers
- 42 people
- Sponsor
- Brown University
Dating Violence, Dating Abuse
A Brief Intervention
This randomized controlled trial (RCT) study is a small scale test of the feasibility and preliminary efficacy of a brief motivational interview-style intervention.
- Trial name
- NCT01632176
- Testing
- Brief, motivational interview and one booster session
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- Boston University
Substance Use, Binge Drinking
Substance Use Screening to Encourage Behavior Change Among Young People in Primary Care
This study evaluates whether completing a short screening questionnaire about health behaviours in the waiting room before a primary care consultation decreases excessive substance use in young people aged 14 to 24 years.
- Conditions
- Substance Use, Binge Drinking, Cannabis Use, Adolescent Behavior
- Trial name
- YP-HEALTH (NCT04146714)
- Testing
- Substance use questionnaire, Physical activity questionnaire
- Where
- Switzerland
- Volunteers
- 840 people, healthy volunteers welcome
- Sponsor
- Prof. Dagmar M. Haller
Alcohol Drinking
Engaging General Practice in the Prevention of Patients With Alcohol Problems
The aim of the study is to test whether or not a tailored multi-component intervention program to increase the activity of general practice teams in the prevention of hazardous and harmful alcohol consumption results in increase…
- Trial name
- NCT00298220
- Testing
- Feedback about patients at risk, Dissemination guideline and patient information letters, Tailored educational training
- Volunteers
- 77 people, healthy volunteers welcome
- Sponsor
- Radboud University Medical Center
Infant, Low Birth Weight
Experimental Study to Reduce Low Birthweight
Introduction: Low birthweight (LBW) is associated with a wide range of short- and long-term consequences and is related to a complex set of maternal psychosocial and behavioural determinants.
- Trial name
- STOP-LBW (NCT04866277)
- Testing
- Fast-track referral for reference services
- Volunteers
- 2,832 people, healthy volunteers welcome
- Sponsor
- Instituto de Saude Publica da Universidade do Porto
Alcohol Use Disorder
Supporting Adolescent Alcohol Treatment With Computer-Based ('Path180') Skills Training
This 8-week clinical trial will test a computer-based skills training program called Path180 with 112 adolescents aged 13 to 19 who are receiving mental health counseling or outpatient substance use treatment.
- Trial name
- NCT07713251
- Testing
- Path180
- Where
- United States
- Volunteers
- 112 people, healthy volunteers welcome
- Sponsor
- Brown University
Smoking, Alcohol Drinking
Smoking and Alcohol Initiation
This study evaluates multi-attribute utility, a modification of subjective expected utility, as a descriptive model of the adolescent's decision to initiate smoking or alcohol use.
- Trial name
- NCT00271843
- Where
- United States
- Volunteers
- 2,600 people
- Sponsor
- National Institute on Drug Abuse (NIDA)
Suicide, Alcohol Use Disorder
Qungasvik (Toolbox): Prevention of Alcohol/Suicide Risk in Alaska Native Youth
For the past 20+ years the investigators have focused on addressing two interrelated public health issues, alcohol use disorder (AUD) and suicide in Alaska.
- Trial name
- NCT05400135
- Testing
- Qungasvik (Tools for Life)
- Where
- United States
- Volunteers
- 542 people, healthy volunteers welcome
- Sponsor
- University of Alaska Fairbanks
Type 2 Diabetes, Inflammation
Effect of Alcohol on Cephalic Phase Reflex and Gene Expression
Moderate alcohol consumption has consistently been associated with lowered risk of developing type two diabetes mellitus compared to abstainers and heavy drinkers.
- Conditions
- Type 2 Diabetes, Inflammation, Carbohydrate&Lipid Metabolism, Oral Processing
- Trial name
- AR22 (NCT00652405)
- Testing
- alcohol
- Where
- Netherlands
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- TNO
Alcohol Drinking
High Schools- High on Life: an Intervention to Reduce Excessive Drinking in Danish High Schools
High schools High on life' intervention is a high school-based, multi-component intervention guided by theory, evidence, and empirical findings to reduce excessive drinking among Danish high school students.
- Trial name
- NCT03906500
- Testing
- High schools High on Life
- Where
- Denmark
- Volunteers
- 3,682 people, healthy volunteers welcome
- Sponsor
- University of Southern Denmark
Obesity
Weight Gain in First-year University Students
The transition to university from secondary school comes with many changes to living arrangements, dietary and alcohol intake, physical activity, and stress.
- Trial name
- NCT05856734
- Testing
- Weight and body composition change, Change in dietary intake, Change in physical activity
- Where
- United Kingdom
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Aberdeen
Alcoholism
Stand Down-Think Before You Drink: An RCT of a Mobile App for Hazardous Drinking With Peer Phone Support
Hazardous drinking is common among Veteran primary care patients and increases risk for more costly and complex medical problems over the long-term. Yet, the vast majority of these Veterans go untreated.
- Trial name
- PS-Stand Down (NCT05473598)
- Testing
- Stand Down app, Peer-Supported Stand Down, Usual Care
- Where
- 2 sites in United States
- Volunteers
- 234 people
- Sponsor
- VA Office of Research and Development
Psychosis, Alcohol Use Disorder
Piloting of an Intervention to Reduce Problematic Alcohol Use in Early Phase Psychosis Patients
A focus of research for youth and Emerging Adults with early phase psychosis (EPP) has been cannabis use. However, this focus has led to overlooking the possible negative influence of another legal recreational drug, alcohol.
- Trial name
- NCT05365347
- Testing
- Cognitive Enhancement Therapy (CET)
- Where
- Canada
- Volunteers
- 24 people
- Sponsor
- Nova Scotia Health Authority
Alcohol-related Disorders, Drinking and Driving
Evaluation of an School-based Alcohol Prevention Program for Middle School Students
The purpose of this research is to create and evaluate the efficacy of an exciting (fun to use), and potentially disseminable computer-based prevention program, Click City®: Alcohol, for use by 7th graders with a booster in 8th…
- Conditions
- Alcohol-related Disorders, Drinking and Driving, Neurological Impairment
- Trial name
- AlcoholINET (NCT01847183)
- Testing
- Click City®: Alcohol
- Where
- United States
- Volunteers
- 2,300 people
- Sponsor
- Oregon Research Institute
Alcoholism
Trial Testing the Effect of Strategies on Performance of Brief Intervention Programmes for Harmful Alcohol Consumption
The overall objective is to study if training and support, financial reimbursement and referral to an internet based brief intervention programme, singly or in combination, may increase implementation of evidence based methods of…
- Trial name
- ODHIN_RCT (NCT01501552)
- Testing
- Training and support (T&S), Financial incentive, E-SBI (online screening and brief intervention)
- Where
- 10 sites in Netherlands, Poland and 3 more
- Volunteers
- 120 people
- Sponsor
- Fundacion Clinic per a la Recerca Biomédica
Chronic Pancreatitis, Genetic Mutation
An Observational Study on the Natural Course of Chronic Pancreatitis
To explore the impact on genetic and environmental factors for clinical manifestation, and the progression of chronic pancreatitis, including development of pancreatic insufficiency and other complications.
- Conditions
- Chronic Pancreatitis, Genetic Mutation, Smoking, Tobacco, Drinking, Alcohol
- Trial name
- NCT04574297
- Testing
- smoking and alcohol assumption, genetic sequencing
- Volunteers
- 798 people
- Sponsor
- Changhai Hospital