Clinical trials: Aldosteronism
Hypertension, Dialysis
Does Aldosterone Cause Hypertension by a Non-Renal Mechanism?
It is well known that Aldosterone (aldo) can cause hypertension (HBP). Since aldo is known to cause the kidney to retain sodium (Na) and Na retention is known to cause HBP, it has been thought that the mechanism by which aldo…
- Conditions
- Hypertension, Dialysis, Hyperaldosteronism
- Trial name
- NCT00553722
- Testing
- Eplerenone
- Where
- Israel
- Volunteers
- 27 people
- Sponsor
- Shaare Zedek Medical Center
Primary Aldosteronism, Primary Aldosteronism Due to Aldosterone Producing Adenoma
A Novel and Efficient Biochemical Screening Strategy for Glucocorticoid-Remediable Aldosteronism: Combined 1-mg Overnight Dexamethasone Suppression Test and Steroid Profile
This prospective observational study evaluates a simplified biochemical screening strategy to differentiate Glucocorticoid-Remediable Aldosteronism (GRA) from Aldosterone-Producing Adenoma (APA).
- Trial name
- NCT07700888
- Testing
- 1 mg overnight dexamethasone inhibition test
- Where
- China
- Volunteers
- 50 people
- Sponsor
- Peking Union Medical College Hospital
Primary Aldosteronism Concurrent With Autonomous Cortisol Secretion
Accuracy of 68Ga-Pentixafor PET/CT for Subtypting Diagnosis in Patients With Primary Aldosteronism Concurrent With Autonomous Cortisol Secretion
To evaluate the accuracy of 68Ga-Pentixafor PET-CT in the classification diagnosis of primary aldosteronism concurrent with autonomous cortisol secretion patient, using AVS and/or postoperative remission as the reference standard…
- Trial name
- ABOARD (NCT06635993)
- Testing
- 68Ga-Pentixafor PET/CT
- Where
- China
- Volunteers
- 97 people
- Sponsor
- Qifu Li
Idiopathic Hyperaldosteronism, Hyperaldosteronism
Superselective Adrenal Arterial Embolization Versus Oral Spironolactone for Treatment of Idiopathic Hyperaldosteronism
Idiopathic hyperaldosteronism (IHA) represents about 65% of primary hyperaldosteronism cases. Although mineralocorticoid receptor antagonists (MRAs) are the standard first-line treatment, they are often limited by adverse…
- Trial name
- NCT07328230
- Testing
- Superselective Adrenal Arterial Embolization, Spironolactone
- Where
- 3 sites in China
- Volunteers
- 172 people
- Sponsor
- Chinese Academy of Medical Sciences, Fuwai Hospital