Clinical trials: Alteration of Cognitive Function
SARS-CoV-2 Infection, Cognitive Change
The ACDC Study Assessing Cognitive Deterioration in COVID-19
The long-term impact and effects of COVID-19 are still being determined. However, what is clear, is that some people are still struggling following a period of illness with COVID-19.
- Conditions
- SARS-CoV-2 Infection, Cognitive Change, Cognitive Dysfunction
- Trial name
- ACDC (NCT05855434)
- Testing
- Magnetic Resonance Imaging
- Where
- United Kingdom
- Volunteers
- 30 people
- Sponsor
- NHS Grampian
Children and Adolescents Inpatient in Psychiatric Hospital
Chess Training as add-on Intervention for Adolescents With Psychiatric and Psychosomatic Disorders
In the planned study, the effect of chess training on the cognitive abilities of children and adolescents with psychiatric and psychosomatic illnesses will be investigated in a naturalistic setting.
- Trial name
- NCT05698615
- Testing
- Chess training
- Where
- Germany
- Volunteers
- 59 people
- Sponsor
- Central Institute of Mental Health, Mannheim
Kindergarten Children
Board Games at Kindergarten (5 Years Old) to Improve Cognitive and Emotional Processes
Cognitive (i.e. executive functions, memory) and socio-emotional (i.e. affection recognition) processes emerges at first years. These processes have been frequently related to adequate academic performance in the scientific…
- Trial name
- NCT06304454
- Testing
- Board game intervention
- Where
- Spain
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Brain In Game scientific-technical service
Psychosis
Mechanisms of Cognitive Change
This study will determine whether targeted cognitive training, a low-cost and low-risk commercial cognitive remediation therapy, directly impacts therapeutic targets as well as secondary outcomes in college undergraduates.
- Trial name
- CTCS (NCT04103775)
- Testing
- Cognitive Remediation, Active Control
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Colorado State University
Microbial Colonization, Atopic Dermatitis
Nationwide Research on the Rewilding of Kindergarten Yards
Biodiversity is essential for nature and human well-being. Land use has reduced biodiversity in cities that is associated with altered commensal microbiota and a rising burden of immunological disorders among urban children.
- Conditions
- Microbial Colonization, Atopic Dermatitis, Asthma in Children, Allergy
- Trial name
- Vahvistu (NCT06390878)
- Testing
- Biodiversity, Playground equipment
- Where
- 2 sites in Finland
- Volunteers
- 320 people, healthy volunteers welcome
- Sponsor
- Natural Resources Institute Finland
Cognitive Change
COgnitive Dynamics in Early Childhood
The goal of this accelerated longitudinal observational cohort study is to advance our understanding of cognitive variability in children aged 7 to 10 at first measurement.
- Trial name
- CODEC (NCT06330090)
- Where
- Netherlands
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Radboud University Medical Center
Cognitive Change, Well-Being, Psychological
Trout Consumption in Young Children and Families and Brain Health
Regular fish consumption may support brain health. Trout lines developed in Idaho contain higher levels of omega-3 fatty acids, nutrients important for human cognition and mental wellbeing.
- Trial name
- NCT06721468
- Testing
- Trout, Child-centered nutrition phrases, Puzzle
- Where
- 2 sites in United States
- Volunteers
- 99 people, healthy volunteers welcome
- Sponsor
- University of Idaho
Emotion Regulation
Intervention in a Small-scale Study of Game Based Cognitive Change Skills
This activity will have the objectives of preliminary testing user satisfaction, the feasibility of the platform and its preliminary efficacy
- Trial name
- NCT05424601
- Testing
- Rethink game, PsyPills
- Where
- Romania
- Volunteers
- 165 people, healthy volunteers welcome
- Sponsor
- Babes-Bolyai University
Type 1 Diabetes Mellitus, Cognitive Change
The VRIF Trial: Hypoglycemia Reduction With Automated-Insulin Delivery System
The objective of this pilot study is (i) to test the use of an Artificial Pancreas (AP) System as a viable therapy treatment for two vulnerable populations: 6 to 10 year-old and adults older ≥65 years old with T1D; (ii) to assess…
- Trial name
- NCT03674281
- Testing
- SAP, CLC
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of Virginia
Adolescent Behavior, Dental Plaque
Evaluating the Effectiveness of a Cognitive Behavioral Intervention (CBI)
This is a Phase III, randomized, one-center, three arm parallel group, open label and single blind clinical study to evaluate the effectiveness of a cognitive behavioral intervention (CBI) adjunctive to a smart powered toothbrush…
- Conditions
- Adolescent Behavior, Dental Plaque, Gingivitis, Cognitive Change
- Trial name
- NCT05782348
- Testing
- Cognitive behavioral intervention, Colgate smart toothbrush
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Howard University
Cognitive Change, Development, Adolescent
Enhancement of Learning and Memory Following Supplementation With Juice PLUS+® OMEGA in an Adolescent Population
This study aims to investigate the effect of chronic supplementation with a commercially available, plant-derived, omega-3 intervention and cognitive performance in adolescent participants aged 13-14 years.
- Trial name
- AdCog-O (NCT05581108)
- Testing
- Juice PLUS+® OMEGA
- Where
- United Kingdom
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- University of Reading
Cognitive Change, Beta-Thalassemia
Assessment of Cognitive Function, Fatigue and Health Related Quality of Life in Children With Beta Thalassemia
This study aims to: Assess the cognitive function in children with beta thalassemia Evaluate the fatigue in beta thalassemic children Assess the health related quality of life measures in children with beta thalassemia.
- Conditions
- Cognitive Change, Beta-Thalassemia, Fatigue, Quality of Life
- Trial name
- NCT05469230
- Where
- Egypt
- Volunteers
- 168 people, healthy volunteers welcome
- Sponsor
- Cairo University
Child, Only, Narration
Effects of a Group EMDR Intervention on Narrative Complexity and Specificity of Autobiographical Memories: the Hug the Child Study (HTC)
Background and study aims: The Eye Movement Desensitization and Reprocessing Group Protocol with Children (EMDR-GP/C) was first developed by Korkmazlar following the Marmara earthquake in Turkey in 1999 and can be adapted for…
- Conditions
- Child, Only, Narration, Memory Dysfunction, Distress, Emotional
- Trial name
- HTC (NCT05319002)
- Testing
- Group EMDR
- Where
- Italy
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- University of Pisa
Dementia, Mild Cognitive Impairment
Video Games to Track Cognitive Health
The purpose of this study is to assess cognitive function using a rapid, portable, computerized neurocognitive testing device in a wide variety of clinical settings.
- Conditions
- Dementia, Mild Cognitive Impairment, Cognitive Impairment, Cognitive Decline
- Trial name
- NCT03608722
- Testing
- SLUMS, MMSE, MoCA
- Volunteers
- 2,500 people, healthy volunteers welcome
- Sponsor
- BrainCheck, Inc.
Behavioral
Cognitive Changes in Childs After Anesthesia / Surgery
The role of surgical stress and anesthesia is unknown in the early childhood. In vitro and animal studies showed a risk for treatment with anesthesia in the developmental brain.
- Trial name
- NCT02658526
- Testing
- anesthesia - surgery
- Where
- Germany
- Volunteers
- healthy volunteers welcome
- Sponsor
- Konstanze Plaschke
Sleep Disorder, ADHD
Sleep Patterns in Children and Adolescents With ADHD
This study is aimed to find out Sleep profile differences in children and adolescents with and without ADHD,Relationship between sleep profile disturbance and ADHD symptoms, Impact of sleep disturbance on cognition functions and…
- Conditions
- Sleep Disorder, ADHD, Cognitive Change
- Trial name
- NCT03737552
- Testing
- Polysomnography
- Where
- Egypt
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Assiut University
Head Trauma, Cognitive Change
Reducing Head Impact Exposure in Hawaii High School Football
This three-year study will determine the effectiveness of a helmetless tackling training intervention to decrease head impact exposure in Hawaiian high school football players.
- Conditions
- Head Trauma, Cognitive Change, Confidence, Self, Sports Injuries in Children
- Trial name
- HuTT808 (NCT04020874)
- Testing
- HuTT-2x, HuTT-4x
- Where
- United States
- Volunteers
- 496 people, healthy volunteers welcome
- Sponsor
- University of Massachusetts, Lowell
Cognitive Change, Child Development
Conectar Jugando: Board Games in Rural Elementary Classrooms (6-12 Years Old) to Improve Executive Functions
The use of board games in classrooms has been increasing in recent years. Education and psychology professionals have found in the board game a way to train some key cognitive processes for good academic development: executive…
- Trial name
- CJ-Rural (NCT05267730)
- Testing
- Conectar Jugando Game Program
- Where
- Spain
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- Brain In Game scientific-technical service
Cognitive Change
Improving Clinical Decision Making Skills for Myanmar Physical Therapists by Series of Workshop
This study aims to improve the Clinical Decision Making (CDM) skills of a group of Myanmar physical therapists by series of educational workshops that will introduce them to and guide them through the decision making process by…
- Trial name
- NCT03149146
- Testing
- Clinical Decision Making (CDM) Workshop, Clinical Decision Making (CDM) Workbook
- Where
- Burma
- Volunteers
- 59 people, healthy volunteers welcome
- Sponsor
- Mahidol University
Cognitive Change, Motor Activity
Group Music Practice Enhances Development
This randomized controlled trial shows for the first time that focused musical instrumental practice as compared to traditional sensitization to music provokes multiple transfer effects in the cognitive and sensorimotor domain.
- Trial name
- OC (NCT04200794)
- Testing
- musical instrumental training, sensitization to music
- Where
- Switzerland
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- School of Health Sciences Geneva