Clinical trials: Ambulation Disorder, Neurologic
Cerebrovascular Accident
Can Arm and Leg Cycling Exercise Improve Walking After Stroke
It has been found that arm and leg cycling is similar to walking. Thus, the objective of this research is to determine if arm and leg cycling can be used to improve walking ability in a post-stroke population.
- Trial name
- NCT02316405
- Testing
- Arm and Leg Cycling Exercise for Walking after Stroke
- Where
- Canada
- Volunteers
- 20 people
- Sponsor
- University of Victoria
Osteoporosis, Cerebral Palsy
Use of Oral Bisphosphonates in the Treatment of Osteoporosis of Non-walking Children With Cerebral Palsy
It is a double blind randomized study aiming at estimating the efficiency of oral bisphosphonates on the decrease of osteoporosis by comparing the evolution of densitometric values between two groups of children (treatment versus…
- Trial name
- NCT00822029
- Testing
- FOSAMAX
- Where
- France
- Volunteers
- 2 people
- Sponsor
- Department of Clinical Research and Innovation
Children With Cerebral Palsy
An In-Shoe Device to Monitor Toe-Walking in Children With Cerebral Palsy
The present project will focus on evaluating the technical efficacy of the in-shoe gait monitoring device (ActiveGait) through laboratory based biomechanical gait assessments of children who exhibit gait deviations due to CP or…
- Trial name
- NCT01684254
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- Spaulding Rehabilitation Hospital
Parkinson Disease
Effects of an Independent Walking Program With Walking Poles in People With Parkinson Disease
Study Purpose: The purpose of the study is to compare changes in activity levels and walking in people with Parkinson disease after an 8-week independent walking program with or without using walking poles.
- Trial name
- ActivatePD (NCT06908135)
- Testing
- Independent walking program using walking poles, Independent walking program without walking poles
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- Pacific Northwest University of Health Sciences
Cerebral Palsy (CP)
Cerebral Palsy: Ankle Foot Orthoses - Footwear Combinations
Ambulatory children with cerebral palsy (CP) demonstrate altered lower limb biomechanical alignment in walking (e.g. excessive hip/knee flexion or equinus during stance) and experience walking activity limitations that negatively…
- Trial name
- CP-AFOFC (NCT03756571)
- Testing
- Ankle Foot Orthoses-Footwear Combination, Traditional Solid Ankle AFO (TSAFO)
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- Seattle Children's Hospital
Phenylketonurias, Non Alcoholic Fatty Liver
Walking Program in Fatty Liver Children With Phenylketonuria
phenylketonuria (commonly known as PKU) is an inherited disorder that increases the levels of a substance called phenylalanine in the blood.
- Trial name
- NCT06718842
- Testing
- walking free online supervised program
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Cairo University
Cerebral Palsy
Isokinetic Strength Training in Children With Hemiparetic Cerebral Palsy
This study endeavored to assess the effect of an isokinetic strength training (IsoK-ST) program on weight-bearing symmetry, gait-symmetry, and dynamic balance in children with hemiparetic cerebral palsy (HCP).
- Trial name
- NCT04907448
- Testing
- Physical Therapy
- Where
- Saudi Arabia
- Volunteers
- 36 people
- Sponsor
- Cairo University
Becker Muscular Dystrophy
Safety and Biomarker Response to (+)-Epicatechin in Becker Muscular Dystrophy
This is a Phase 1, open-label, dose escalation study aimed at evaluating the safety, early efficacy and potential biomarkers of (+)-epicatechin in patients with Becker or Becker-like Muscular Dystrophy (BMD).
- Trial name
- NCT04386304
- Testing
- (+)-Epicatechin
- Where
- 3 sites in United States
- Volunteers
- 22 people
- Sponsor
- Epirium Bio Inc.
Home-based Programs, EzyGain
EMMVIES : Walking Training at Home in VIrtual Reality for Children With Chronic Illnesses Impacting Physical Health
Over the past 30 years, the prevalence of congenital or acquired chronic diseases in children has risen, affecting between 10 and 30% of them, or at least 100,000 children in France.
- Conditions
- Home-based Programs, EzyGain, AMY Treadmill, Cerebral Palsy
- Trial name
- EMMVIES (NCT07021638)
- Testing
- EMMVIES program
- Where
- France
- Volunteers
- 30 people
- Sponsor
- University Hospital, Angers
Pulmonary Disease, Autonomic Dysfunction
Meditative Movement for COPD Symptoms in Non-Smoking Flight Attendants
This study will explore the a Qigong based exercise intervention, here referred to as Meditative Movement (MM), to ameliorate the symptoms associated with chronic obstructive pulmonary disease (COPD) and its co-morbidities.
- Conditions
- Pulmonary Disease, Autonomic Dysfunction, COPD
- Trial name
- MMforFA (NCT02612389)
- Testing
- Meditative Movement taught via DVD
- Where
- United States
- Volunteers
- 220 people, healthy volunteers welcome
- Sponsor
- Dartmouth-Hitchcock Medical Center
Blindness
Continued Study of Artificial Vision: Evaluation of the BrainPort® System and Investigation of Visual Ambulation
The purpose of this study is to evaluate the use of an artificial vision system called Brainport system in blind patients To investigate visual, and oculomotor (eye motion) mechanisms involved in the use of the Brainport system.
- Trial name
- BrainPort (NCT02643238)
- Testing
- BrainPort
- Where
- United States
- Volunteers
- 7 people, healthy volunteers welcome
- Sponsor
- Akron Children's Hospital
Spinal Muscular Atrophy
Mechanisms and Treatment of Exercise Intolerance and Persistent Fatigue in Spinal Muscular Atrophy
This study will focus on the pathophysiological underpinnings of reduced exercise capacity and fatigue in ambulatory patients with spinal muscular atrophy (SMA).
- Trial name
- NCT05518773
- Testing
- Observational
- Where
- United States
- Volunteers
- 34 people
- Sponsor
- Columbia University
Cerebral Palsy
Effect of Nordic Walking on Gait-asymmetry Patterns in Children With Hemiparesis
Nordic walking is a physical activity consisting of walking with poles similar to ski poles. The poles are designed for the purpose of activating the upper body during walking.
- Trial name
- NCT05644652
- Testing
- designed physical therapy program, Nordic walking
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Cairo University
Spinal Muscular Atrophy Type 2
GCB-001 in Treatment of Patients With Type II (SMA) Spinal Muscular Atrophy
This study explored dose escalation of single-arm, open, single intrathecal injection in patients with delayed onset type 2 SMA. The investigator plans to conduct 2 cohorts.
- Trial name
- GITOPWTSMA (NCT06772402)
- Testing
- GCB-001
- Where
- China
- Volunteers
- 6 people
- Sponsor
- Genecombio Ltd.
Spastic Cerebral Palsy
Effects of Functional Progressive Strength Training in Children With Spastic Cerebral Palsy
This study focuses on the effects of Functional Progressive Strength Training (FPST) on children with spastic cerebral palsy, a condition characterized by increased muscle tone that affects movement.
- Trial name
- NCT06407869
- Testing
- Functional Progressive Strength Training, Control
- Where
- Pakistan
- Volunteers
- 40 people
- Sponsor
- Riphah International University
Stroke, Knowledge, Attitudes, Practice
Effects of an Educational Intervention on Rehabilitation Clinicians' Practices for Health-related Outcomes After Stroke
The overall aim of this pilot study is to evaluate the feasibility of a study protocol for a future stepped wedge cluster randomized clinical trial (c-RCT) that will investigate the effects of an innovative KT intervention on 1)…
- Conditions
- Stroke, Knowledge, Attitudes, Practice, Physical Disability, Motor Skills Disorders
- Trial name
- NCT03807115
- Testing
- Implementation of stroke mobility guidelines
- Where
- 6 sites in Canada
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- McGill University
Duchenne Muscular Dystrophy
Safety and Efficacy Study of IGF-1 in Duchenne Muscular Dystrophy
The purpose of this study is to determine whether IGF-1 therapy improves or preserves muscle function in Duchenne Muscular Dystrophy (DMD).
- Trial name
- NCT01207908
- Testing
- IGF-1
- Where
- United States
- Volunteers
- 44 people
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Spinal Muscular Atrophy Type 3, Duchenne Muscular Dystrophy (DMD)
Establishing Walking-related Digital Biomarkers in Rare Childhood Onset Progressive Neuromuscular Disorders
The purpose of this research is (1) to identify disease specific walking-related digital biomarkers of disease severity, and (2) monitor longitudinal changes in natural environments, for extended periods of time, in DMD and SMA.
- Trial name
- NCT06839469
- Where
- 3 sites in United States
- Volunteers
- 106 people, healthy volunteers welcome
- Sponsor
- Columbia University
Spinal Muscular Atrophy Type 3, Duchenne Muscular Dystrophy
Wearable Technology to Assess Gait Function in SMA and DMD
The purpose of this project is to devise instrumented insoles capable of accurately measuring gait at each footfall, over multiple hours in any environment.
- Trial name
- NCT04193085
- Testing
- Observational
- Where
- United States
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Columbia University
Cerebral Palsy
Brain Change After Fun, Athletic, Sports-skill Training (BeFAST)
The purpose of this study is to determine the associations between changes in neural activity and structure, advanced gross motor skills, gait characteristics, and physical activity participation following a gait-related…
- Trial name
- BeFAST (NCT02584491)
- Testing
- Functional gait-related training
- Where
- Canada
- Volunteers
- 9 people
- Sponsor
- Holland Bloorview Kids Rehabilitation Hospital