Clinical trials: Anaesthesia Induction
Anesthesia; Reaction, Children, Only
Effect of Anesthesia Induction on Cerebral Hemodynamic in Children
General anesthesia induces hemodynamic changes, notably a reduction of arterial blood pressure going up to 30%, that may impact cerebral perfusion and oxygenation.The purpose of this study is to assess the impact of anesthesia on…
- Trial name
- PEDICACHE (NCT04581213)
- Testing
- General anesthesia
- Where
- Canada
- Volunteers
- 50 people
- Sponsor
- St. Justine's Hospital
Burst Suppression, General Anesthesia
Interrater Variability for the Identification of Anesthetic-induced Burst Suppression EEG
Burst suppression describes a specific EEG pattern that can generally indicate a too deep general anesthesia. The pathophysiology of anesthetic-induced Burst Suppression may be distinctly different from the pathophysiology of…
- Conditions
- Burst Suppression, General Anesthesia, Electroencephalogram
- Trial name
- NCT05508386
- Testing
- MATLAB-based interface, showing 50 EEG traces, classification of the EEG-pattern as Burst Suppression possible, yes, no.
- Where
- Germany
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Technical University of Munich
Pediatric Population, Preoperative Anxiety
Comparing the Effectiveness of Virtual Reality in Paediatric Patients
To the best of our knowledge,the investigators found only a study using VR in reducing preoperative anxiety in paediatric population.
- Trial name
- NCT06044753
- Testing
- Virtual Reality Headset
- Where
- Malaysia
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Universiti Kebangsaan Malaysia Medical Centre
Anesthesia, Pediatrics
Chocolate or Sevoflurane: Use of Parosmia to Facilitate More Cooperative Inhalation Inductions in Children
Children undergoing surgery and anesthesia are often negatively impacted by anxiety and fear in the preoperative period. Routine inhalational anesthetic induction is a unique aspect of pediatric anesthesia.
- Trial name
- NCT06449157
- Testing
- Inhalation induction with parosmia
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Johns Hopkins University
Anxiety, Preoperative Anxiety
Effect of Parental Presence on Anxiety of Children During Induction of Anesthesia
Anxiety is when children feel scared, worried, or nervous before or during anesthesia induction. This can happen because they don't know what's happening, are scared of the hospital or medical equipment, or are worried about…
- Trial name
- PPIA (NCT06709443)
- Where
- Pakistan
- Volunteers
- 75 people
- Sponsor
- Liaquat National Hospital & Medical College
Safety Issues
Paracetamol Hypothermia Children
Transient Acetaminophen Induced Hypothermia in Pediatrics Population Undergoing General Anesthesia
- Trial name
- NCT04608669
- Testing
- Paracetamol
- Where
- Lebanon
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Saint George Hospital
Fasting
Blood Glucose Levels in Children During Anesthesia
This cross-sectional study aims to investigate blood glucose levels in children during general anesthesia and explore the incidence of hypoglycemia after anesthesia induction in relation to preoperative fasting.
- Trial name
- NCT06915493
- Testing
- General Anesthesia
- Where
- Iceland
- Volunteers
- 350 people
- Sponsor
- Landspitali University Hospital
General Anaesthesia During Pregnancy
Intelligence and Neurodevelopmental Disorders After Prenatal Exposure to General Anaesthesia
Every year in the European Union, thousands of babies are exposed to anaesthesia before they are born because their mothers need surgery during pregnancy.
- Trial name
- PAE-IQ (NCT06633406)
- Testing
- Age-appropriate Wechsler Intelligence Test, Disruptive Behavior Disorders Rating Scale, Social Responsiveness Scale
- Where
- 3 sites in Belgium
- Volunteers
- 192 people, healthy volunteers welcome
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Continuous Positive Airway Pressure, Hypoxia
Positive Pressure at Induction of Anesthesia in Children
SCENARIO: Hypoxemia is one of the most common adverse events during the induction of general anesthesia and may culminate with more serious complications such as cardiac arrest and death.
- Conditions
- Continuous Positive Airway Pressure, Hypoxia, General Anesthesia
- Trial name
- NCT03432390
- Testing
- Continuous Positive Airway Pressure, Open system ventilation
- Where
- Brazil
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Instituto Materno Infantil Prof. Fernando Figueira
Movement After Intravenous Cannulation
Optimum Time for Intravenous Cannulation After Induction With Sevoflurane in Pediatric Patient
This study aimed to determinate effective dose 95 (ED95) intravenous cannulation in pediatric patient after induction of sevoflurane 8 vol%
- Trial name
- NCT04284579
- Testing
- IV cannula
- Where
- Indonesia
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Universitas Indonesia
Anaesthesia, Anesthesia Depth Monitoring
Monitoring the Depth of Anesthesia and Nociception During the Induction of General Anesthesia in Pediatric Patients
Perioperative assessment of adequate depth of anesthesia and analgesia is currently a recommended part of routine anesthesia practice for all surgical procedures.
- Trial name
- ANIGAPP (NCT07245654)
- Where
- Czechia
- Volunteers
- 100 people
- Sponsor
- Brno University Hospital
Anxiety at Induction of Pediatric Anesthesia
Improving the Quality of Anesthesia Induction by Reducing Preoperative Anxiety in the Operating Room
Preoperative anxiety refers to a range of physical and/or psychological manifestations, which can have a significant impact on medical outcomes and the experience of the child and their parents.
- Trial name
- QUALIN (NCT06972420)
- Testing
- Hypnosis session
- Where
- France
- Volunteers
- 60 people
- Sponsor
- Assistance Publique Hopitaux De Marseille
Oxygen Deficiency
High-flow Nasal Cannula for Pediatric Anesthetic Induction
Endotracheal intubation in infants often involves more than one attempt, and oxygen desaturation is common. It is unclear whether nasal high-flow therapy, which extends the time to desaturation during elective intubation in…
- Trial name
- NCT05578131
- Testing
- high flow nasal oxygen, face mask
- Where
- South Korea
- Volunteers
- 132 people
- Sponsor
- Seoul National University Hospital
Hypotension on Induction
Hypotension in Children With Down Syndrome With Anesthesia Induction
Children generally undergo induction of anesthesia by inhalation of sevoflurane. Children with Down Syndrome experience bradycardia with induction of anesthesia using sevoflurane.
- Trial name
- NCT04603469
- Testing
- Non invasive blood pressure
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- Baylor College of Medicine
Anesthetic, Sevoflurane
Sevoflurane Concentrations in Children
The sevoflurane concentrations (as well as vital signs, child's date of birth, type of surgery) will be recorded during the first 10 minutes of anesthesia.
- Conditions
- Anesthetic, Sevoflurane, Age
- Trial name
- NCT06510803
- Testing
- The washin of sevoflurane in the GE Ohmeda workstation
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- State University of New York at Buffalo
Pain on Propofol IV Injection
In Children, Does Using a Synera Patch Decrease Pain When Injecting Propofol at Anesthesia Induction?
The purpose of this study is to evaluate if the Synera Patch (lidocaine/tetracaine patch), used to numb the skin before IV placement, is effective in reducing pain associated with propofol IV administration when inducing general…
- Trial name
- Synera patch (NCT01576770)
- Testing
- lidocaine/tetracaine transdermal patch (NDC 43469-864-01), Gebauer's Ethyl Chloride
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- The University of Texas Health Science Center, Houston
Neuromuscular Blockade
Comparing Reversal With Neostigmine and Sugammadex in Paediatric
A reversal agent is commonly given to improve neuromuscular function after intra-operative administration of non-depolarizing neuromuscular blocking agents.
- Trial name
- JS (NCT03137290)
- Testing
- Neostigmine, Sugammadex Sodium
- Where
- Malaysia
- Volunteers
- 80 people
- Sponsor
- Universiti Sains Malaysia
Opioid-Induced Respiratory Depression, Postoperative Complications (Cardiopulmonary)
Pupillometry in Identifying Risk of Postoperative Opioid-induced Respiratory Depression in Children Undergoing Tonsillectomy
This study will evaluate whether quantitative pupillometry measurements can be used to identify children at risk for postoperative opioid-induced respiratory depression (OIRD) following tonsillectomy.
- Conditions
- Opioid-Induced Respiratory Depression, Postoperative Complications (Cardiopulmonary), Respiratory Complications Due to Anesthesia
- Trial name
- NCT07573150
- Testing
- Infrared Pupillometry
- Where
- 2 sites in United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- NeurOptics Inc
Postoperative Recovery
Ketamin Plus Propofol for Anesthesia Induction
ASA I-II 112 pediatric patients will recruit who underwent adenoidectomy-tonsillectomy surgery. Propofol 1 mg/kg + ketamin1 mg/kg (1/1 ratio) for group I; propofol 1,5 mg/kg + ketamin 0,75 mg/kg (2/1 ratio) for group II; propofol…
- Trial name
- NCT04761159
- Testing
- Ketamine
- Where
- Turkey (Türkiye)
- Volunteers
- 112 people, healthy volunteers welcome
- Sponsor
- Cukurova University
Bronchospasm
Bronchospasm During Anesthetic Induction: Study of Clinical Characteristics and Treatments Administered According to Etiology
Bronchospasm during anaesthesia is a rare but potentially life-threatening event. They are classically part of IgE-dependent anaphylaxis but can also occur as an independent clinical entity, triggered by inflammatory factors such…
- Trial name
- NCT05025709
- Where
- France
- Volunteers
- 31 people
- Sponsor
- Central Hospital, Nancy, France