Clinical trials: Analgesia
Pain, Acute, Burns
Distraction As Multimodal Pain Management
A randomized controlled trial will be performed at the Ngwelezana Hospital, Empangeni, South Africa. Paediatric patients between the age of 5-12 years with minor and superficial partial thickness burn injuries who require…
- Conditions
- Pain, Acute, Burns, Pediatric ALL
- Trial name
- DISTRACT (NCT06591195)
- Testing
- Distraction by use of kaleidoscope
- Volunteers
- 126 people
- Sponsor
- Radboud University Medical Center
Pain
Nasal Ketamine for Minor Procedures in Children
Nasal Ketamine has previously been tested in children for deep sedation or preoperative anxiolysis. The investigators intend to test the efficacy of low dose nasal Ketamine in children undergoing minor procedures in the emergency…
- Trial name
- NCT02839928
- Testing
- Intranasal ketamine, Intranasal atomizer, EMLA
- Volunteers
- 20 people
- Sponsor
- Kaplan Medical Center
Labor Pain, Dural Puncture Epidural Technique
Two Different Sized Spinal Needles DPE vs Conventional Epidural Technique
DPEA (Dural Puncture Epidural Analgesia) is an alternative to the conventional epidural analgesia and technically a Combined Spinal Epidural (CSE) with omission of intrathecal drugs administration.
- Trial name
- NCT07708909
- Testing
- Dural Puncture Epidural Analgesia 27G, Dural Puncture Epidural Analgesia 25G, Conventional epidural
- Volunteers
- 240 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Labor Pain
Programmed Intermittent Epidural Bolus for Labor Analgesia During First Stage of Labor-3
Until recently, at Mount Sinai Hospital (MSH), epidural analgesia for labor pain was delivered with a pump that could only provide continuous infusion of the freezing medication in combination of pushes of medication activated by…
- Trial name
- NCT02887222
- Testing
- Bupivacaine
- Where
- Canada
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Samuel Lunenfeld Research Institute, Mount Sinai Hospital
Labor Pain, Pregnancy Outcomes
The Association Between Epidural Labor Analgesia and Pregnancy Outcomes
Labor analgesia can alleviate intrapartum pain, in the importance of the delivery is very obvious.But some researches think labor analgesia may affect the progress of labor, increase the cesarean section rate.This research adopts…
- Conditions
- Labor Pain, Pregnancy Outcomes, Psychological Disorder
- Trial name
- NCT03381495
- Testing
- Ropivacaine Hydrochloride, Sufentanil
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Deng Dongrui
Laceration of Skin
IN Ketamine vs IN Midazolam and Fentanyl for Laceration Repair
Often, repair of the cuts (laceration repair) proves to be traumatic for the children and the parents. Nasal spray (Intranasal/IN) approaches for procedural pain reduction, such as during dental work, have been demonstrated to…
- Trial name
- NCT03528512
- Testing
- Ketamine, Midazolam and fentanyl
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- Corewell Health East
Pain Management, Anxiety
Distraction With Virtual Reality From Pain and Anxiety for Patients With Hematological Malignancies
The goal of this clinical trial] is to study the effectiveness of Virtual Reality (VR) in reducing pain and anxiety during painful procedures for patients with hematological malignancies The main question[s] it aims to answer…
- Conditions
- Pain Management, Anxiety, Procedures, Hematological Neoplasms
- Trial name
- NCT07085065
- Testing
- VR session
- Where
- Tunisia
- Volunteers
- 365 people
- Sponsor
- Yesmine Amara
Pain Management, Spinal Fusion
Intrathecal Morphine Versus Epidural Extended Release Morphine for Pediatric Patients Undergoing Spinal Fusion
This study plans to learn more about preventing pain in children who are having posterior spinal fusion surgery using two different kinds of morphine (a pain medicine).
- Conditions
- Pain Management, Spinal Fusion, Scoliosis
- Trial name
- NCT00880607
- Testing
- Intrathecal morphine, Extended Release Epidural Morphine
- Where
- United States
- Volunteers
- 84 people
- Sponsor
- University of Colorado, Denver
Total Hip Replacement
Effectiveness of Patient-Controlled Intravenous Analgesia (PCIA) With Fentanyl
To enhance post-operative pain management, patient-controlled intravenous analgesia (PCIA) has been employed. The fentanyl background PCIA therapy was created to solve the limitations of IV-based PCIA, such as programming errors…
- Trial name
- NCT05429567
- Testing
- Fentanyl
- Where
- Egypt
- Volunteers
- 70 people
- Sponsor
- Egymedicalpedia
Musculoskeletal Pain, School Health
Effectiveness of Health Education Program on Musculoskeletal Pain Management in Primary School Students
Musculoskeletal pain during childhood can negatively affect school attendance, physical activity, and social participation. This study will evaluate the effectiveness of the school-based health education program 'SocLaLola'…
- Conditions
- Musculoskeletal Pain, School Health, Sedentary Behaviors, Health Education
- Trial name
- LOLA (NCT07160478)
- Testing
- School Health Program
- Where
- Spain
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- Universitat de Lleida
Ropivacaine, Infraumbilical Surgery
Caudal Ropivacaine With or Without Dexmedetomidine for Post Operative Analgesia
The goal of this clinical trial is to evaluate the postoperative analgesic effects of caudal Ropivacaine with or without Dexmedetomidine in pediatric infraumbilical surgery.
- Conditions
- Ropivacaine, Infraumbilical Surgery, Dexmedetomidine, Analgesia
- Trial name
- NCT05979558
- Testing
- ropivacaine with dexmedetomidine
- Where
- Nepal
- Volunteers
- 62 people
- Sponsor
- National Academy of Medical Sciences, Nepal
Chronic Pain Management
Using Virtual Reality Applications for Younger Patients With Chronic Pain
In this study, patients who are 7-21 years of age and have chronic pain affecting their head, neck, and/or upper limb will participate in 6 once-weekly sessions.
- Trial name
- NCT07630350
- Testing
- Virtual reality gaming, Physical therapy exercises
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Elizabeth Pickle
Cancer
PECTORAL PLANE BLOCK COMPAIRED TO ERECTOR SPINAE PLANE BLOCK IN MULTIMODAL ANALGESIA FOR MASTECTOMY PATIENTS IN SOUTH ASIAN POPULATION -A PROSPECTIVE RANDOMISED CONTROL TRIAL
This prospective randomized controlled trial was conducted at the Department of Anesthesia, Shaukat Khanum Memorial Cancer Hospital and Research Centre (SKMCH\&RC), Lahore.
- Trial name
- NCT07197177
- Testing
- regional block
- Where
- Pakistan
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Shaukat Khanum Memorial Cancer Hospital & Research Centre
Post Operative Pain, Inguinal Hernia
Comparison of Two Different Analgesic Regional Block Techniques in Pediatric Patients Undergoing a Hernia Repair
Lower abdominal operations; especially inguinal hernia repairs are one of the most frequently performed operations in the daily practice of pediatric surgeries.Regional anesthesia techniques are frequently and effectively used…
- Trial name
- NCT05896072
- Testing
- Erector Spinae Plane Block, Caudal Block
- Where
- 7 sites in Turkey (Türkiye)
- Volunteers
- 66 people
- Sponsor
- Abant Izzet Baysal University
Sickle Cell Disease
Assessing Molecular Mechanisms and Effects of Music Therapy in Youth With Sickle Cell Disease Using Single-cell RNA-sequencing
The goal of this clinical trial is to evaluate whether a 4-week music therapy (MT) intervention can reduce chronic pain and improve psychosocial outcomes in youth with sickle cell disease (SCD).
- Trial name
- NCT07562451
- Testing
- Music Therapy, Standard of Care
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Emory University
Analgesia, Sedation and Analgesia
Dexmedetomidine as an Adjunct to Fentanyl for Term Neonates on Mechanical Ventilation
Despite well conducted studies on pain management in mechanically ventilated neonates, there is still a need for exploration of appropriate and accurate pharmacological management strategies for this ongoing pain, and assessment…
- Conditions
- Analgesia, Sedation and Analgesia, Neonatal, Mechanical Ventilation in Neonates
- Trial name
- NCT07241351
- Testing
- Dexmedetomidine, fentanyl 1mcg/kg/hr, fentanyl 0.5 mcg/kg/hr
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Ain Shams University
Analgesia
Peroperative Effect of Regional Anesthesia in Hip Surgery
A total of 120 patients scheduled for surgical operation due to hip fracture were divided into two randomized groups. The first group received pericapsular nerve group (PENG) block, while the second group received lumbar erector…
- Trial name
- NCT05960253
- Testing
- Pericapsular Nerve Group Block, Lumber Erector Spinae Plane Block
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people
- Sponsor
- Ankara City Hospital Bilkent
Vaso-occlusive Crisis
Oral Ketamine for Treatment of Vaso-Occlusive Pain
The purpose of this study is to learn more about the feasibility of oral ketamine for the treatment of painful sickle-cell crises in children and adolescents as a supplement to intravenous (IV) opioids.
- Trial name
- NCT05378555
- Testing
- Ketamine Hydrochloride
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Boston Children's Hospital
Ultrasound, Serratus Anterior Plane Block
Ultrasound Guided Serratus Anterior Plane Block Versus Thoracic Erector Spinae Plane Block for Post Operative Analgesia in Pediatrics Undergoing Thoracotomy
This study is designed to compare the post operative analgesic effect of serratus anterior plane block versus thoracic erector spinae plane block in pediatrics undergoing thoracotomy
- Conditions
- Ultrasound, Serratus Anterior Plane Block, Thoracic Erector Spinae Plane Block, Post Operative Analgesia
- Trial name
- NCT06862518
- Testing
- Control group, Serratus Anterior Plane Block (SAPB) group, Erector Spinae Plane Block (ESPB) group
- Where
- Egypt
- Volunteers
- 105 people
- Sponsor
- Tanta University
Empathy
The Test of Those Managing Pain With Their Own Pain
The study aims primarily to investigate physicians' awareness of their health status, empathy towards patients, and management processes through a questionnaire targeting physicians who diagnose and manage patients' pain.
- Trial name
- NCT06939543
- Testing
- empathy
- Volunteers
- 175 people, healthy volunteers welcome
- Sponsor
- Haseki Training and Research Hospital
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