Clinical trials: Analgesic, Opioid
Tooth Extraction
De-Implementing Opioids for Dental Extractions
The overarching goal of this project is to de-implement the reliance on opioid analgesics and to implement reliance on non-opioid analgesics to manage postoperative pain following dental extractions.
- Trial name
- DIODE (NCT03584789)
- Testing
- Clinical Decision Support, Patient education
- Where
- United States
- Volunteers
- 5,722 people
- Sponsor
- HealthPartners Institute
Pain
Safety of Twice Daily Oxycodone Hydrochloride Controlled-release Tablets in Children With Moderate to Severe Malignant and/ or Nonmalignant Pain Requiring Opioids
The purpose of this study is to characterize the safety of oxycodone hydrochloride (HCl) controlled-release (CR) tablets in opioid tolerant pediatric patients aged 6 to 16 years, inclusive, with moderate to severe malignant…
- Trial name
- NCT01192295
- Testing
- Oxycodone HCl controlled-release tablets
- Where
- 47 sites in United States, Greece and 6 more
- Volunteers
- 155 people
- Sponsor
- Purdue Pharma LP
Postoperative Pain
An Open-label Study of Hydromorphone Oral Solution in Subjects Aged 28 Days to 16 Years for Postoperative Pain
The primary objective of this study is to characterize the pharmacokinetics and pharmacodynamics of hydromorphone oral solution in pediatric subjects aged 28 days to 16 years inclusive.
- Trial name
- Palladone (NCT00465647)
- Testing
- Hydromorphone
- Where
- 14 sites in United States
- Volunteers
- 116 people
- Sponsor
- Purdue Pharma LP
Musculoskeletal Injury
Oral Analgesic Utilization for CHildhood Musculoskeletal Injuries
Pain management for children presenting to the emergency department (ED) with an injured limb is often under-treated, even though it is known that broken arms and legs cause moderate to severe pain.
- Trial name
- NCT02064894
- Testing
- oral morphine and oral ibuprofen, Oral morphine, Oral ibuprofen
- Where
- 3 sites in Canada
- Volunteers
- 501 people
- Sponsor
- St. Justine's Hospital
Pain Due to Certain Specified Procedures
Pilot Study of Sucrose to Reduce Pain in Sick Babies
Small amounts of sweet tasting sugar water reduces pain in babies during painful blood tests and injections. The investigators do not know if sugar also reduces pain in babies already receiving a continuous infusion of opioid…
- Trial name
- NCT01438008
- Testing
- 24% sucrose po solution
- Where
- Canada
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- Children's Hospital of Eastern Ontario
Post Operative Pain
Parent Nurse Controlled Analgesic in Pediatric Patients With Developmental Delay
The purpose of this study is to compare, the safety, efficacy and level of parent and nurse satisfaction with three methods of opioid administration post-operatively in children (4-18 years of age) with developmental delay.
- Trial name
- PNCA (NCT00743730)
- Testing
- Pain and standard side effect management for PNCA with basal method., Pain and standard side effect management with PNCA without basal, Pain and standard side effect management with IV on an as needed basis method.
- Where
- United States
- Volunteers
- 94 people
- Sponsor
- Medical College of Wisconsin
Pain, Postoperative, Opioid Use
Erector Spinae Plane Blocks for Adolescent Idiopathic Scoliosis
Pediatric spinal fusion (PSF) surgery is a painful procedure that can treat adolescent idiopathic scoliosis (AIS). One technique that can potentially reduce patients' pain levels and need for opioid medication is the…
- Conditions
- Pain, Postoperative, Opioid Use, Recruitment
- Trial name
- NCT04500613
- Testing
- Bilateral Erector Spinae Plane Block with bupivacaine and dexamethasone, No bilateral Erector Spinae Plane Block (no bupivacaine and no dexamethasone)
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Hospital for Special Surgery, New York
Pain, Postoperative
Pain Control in Pediatric Posterior Spine Fusion Patients: The Effect of Gabapentin
The purpose of this study is to evaluate the patient experience when using gabapentin with other pain control medications after posterior spinal fusion surgery for scoliosis in adolescents.
- Trial name
- NCT01977937
- Testing
- Gabapentin 250mg/5mL NDC:59762-5025-01, Simple Syrup
- Where
- United States
- Volunteers
- 55 people
- Sponsor
- Oregon Health and Science University