Clinical trials: Analgesics
a Single-Dose of Etoricoxib, Post-Operative Morphine Consumption
Pre-Emptive Analgesia Efficacy of Etoricoxib for Postoperative Pain
Taken together, studies of the value of pre-emptive analgesia are inconclusive. This randomized, double-blind, dose-ranging, placebo-controlled study was therefore designed to test that a reduction in post-operative morphine…
- Conditions
- a Single-Dose of Etoricoxib, Post-Operative Morphine Consumption, Total Pain Relief Over 8 Hr(TOPAR8), Post Transabdominal Hysterectomy
- Trial name
- NCT00149253
- Testing
- a single-dose of Etoricoxib before induction of anesthesia
- Where
- Thailand
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Khon Kaen University
Inguinal Hernia, Surgery
Analgesia Evaluation of an Ultrasound-guided Technique for Inguinal Hernia Surgery in Children in Children
The basis for the transversalis fascia plane (TFP) block involves infiltration of local anaesthetic blocking the ilioinguinal and iliohypogastric nerve which are located between the fascia of the transversus abdominis muscle and…
- Conditions
- Inguinal Hernia, Surgery, Paediatric
- Trial name
- NCT06883370
- Testing
- ultrasound-guided transversals fascia plane block with ropivacaine
- Where
- Malaysia
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- National University of Malaysia
Abdominal Pain
The Effect of Pain Medication in Children With Acute Abdominal Pain and Its Implication Over the Surgeon's Decision
Surgeons are the individuals who will operate on a patient if it is determined to be necessary after they present with abdominal pain.
- Trial name
- NCT00839787
- Testing
- Morphine Sulfate
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Texas Southwestern Medical Center
Crown Lengthening Procedure With Ostectomy
Analgesic Efficacy of Arnica Montana in Comparison With Diclofenac Sodium Following a Periodontal Surgical Procedure
Introduction: Homeopathy is a deep healing, comprehensive and distinct system originally developed by Samuel Hahnemann about 200 years ago.
- Trial name
- NCT03520595
- Testing
- Arnica 200 drug 3 pills,3 times daily for 3 days, Diclofenac Sodium 50mg twice daily
- Where
- India
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Tatyasaheb Kore Dental College
Inhalation of Nitrous Oxide, Opioid Analgesic Adverse Reaction
Combination of Nitrous Oxide 70% With Fentanyl Intranasal for Procedural Analgosedation in Children
This study analyzes the analgesic efficacy and adverse events of nitrous oxide 70% combined with basic analgetics compared to nitrous oxide 70% with fentanyl intranasal for analgosedation for short and painful procedures in…
- Conditions
- Inhalation of Nitrous Oxide, Opioid Analgesic Adverse Reaction, Pain
- Trial name
- NCT02533908
- Testing
- Fentanyl intranasal, NaCl 0.9% intranasal
- Where
- Switzerland
- Volunteers
- 402 people, healthy volunteers welcome
- Sponsor
- University Children's Hospital, Zurich
Pediatric Obstructive Sleep Apnea Syndrome
Investigating the Safety of Post-surgical Analgesics in Children With Obstructive Sleep Apnea
Every year thousands of young children with obstructive sleep apnea undergo surgery which requires them to be prescribed pain medication.
- Trial name
- NCT01680939
- Testing
- Morphine, Ibuprofen
- Where
- Canada
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Hamilton Health Sciences Corporation
Pain
Analgesic Use and Effectiveness for Dental Procedures
Opioid analgesics prescribed by dentists may contribute to the larger national issue of the use and abuse of the drug. On occasion dental pain may be sufficiently severe to support the use of opioids.
- Trial name
- NCT02929602
- Where
- United States
- Volunteers
- 2,773 people, healthy volunteers welcome
- Sponsor
- Pearl Network
Pain
Analgesic Effect of Oral 25% Glucose Versus Oral 24% Sucrose for Pain Relief During Heel Lance in Preterm Neonates
RESEARCH HYPOTHESIS-In preterm neonates during heel lance oral 25% glucose is more efficacious in reducing pain as compared to oral 24% sucrose when assessed by PIPP(Premature infant pain profile)
- Trial name
- NCT01931020
- Testing
- Sucrose, Glucose
- Where
- India
- Volunteers
- 94 people, healthy volunteers welcome
- Sponsor
- Lady Hardinge Medical College
Analgesia, Post Caserean
Piroxicam Versus Diclofenac for Post Caesarean Section Analgesia
Multimodal analgesic combination of pentazocine-diclofenac has been found to be superior to pentazocine-piroxicam and was associated with a higher level of maternal satisfaction.
- Trial name
- NCT06943092
- Testing
- Piroxicam group, Diclofenac group
- Where
- Nigeria
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- Federal Teaching Hospital Abakaliki
Postoperative Nausea and Vomiting, Postoperative Pain
Dexamethasone for Paediatric Adeno-tonsillectomy - A Dose-finding Study
Adeno-tonsillectomy is a commonly performed surgical procedure in children. Main morbidities are postoperative pain, nausea and vomiting, and haemorrhage.
- Trial name
- NCT00403806
- Testing
- dexamethasone, Saline
- Where
- Switzerland
- Volunteers
- 215 people, healthy volunteers welcome
- Sponsor
- University Hospital, Geneva
Anesthesia, Spinal, Pain
Comparison of Two Analgesic Pretreatment Techniques Before Spinal Needle Insertion for Pain Reduction and Maternal Satisfaction Level Assessment in Women Undergoing LSCS.
Nowadays lower segment cesarean sections are preferably carried out under regional anesthesia due to multiple advantages. Local infiltration of lidocaine or any other anesthetic is used before lumber puncture in many centers to…
- Conditions
- Anesthesia, Spinal, Pain, Pregnancy, Cesarean Section
- Trial name
- NCT04050059
- Testing
- EMLA cream, 2% lidocaine
- Where
- Pakistan
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Aga Khan University
Field Physician Care, Analgesics
Analgesia in ÖAMTC Helicopter Emergency Service in Austria
A sufficient analgesia in injured or sick people is the main goal of physicians treating a patient. In emergency medicine potent analgesia like ketamine or opioids are routinely used.
- Conditions
- Field Physician Care, Analgesics, Hypnotics, Emergencies
- Trial name
- NCT03760302
- Testing
- analgesics, hypnotics
- Where
- Austria
- Volunteers
- 35,000 people, healthy volunteers welcome
- Sponsor
- Medical University Innsbruck
SCS
Multicenter Outcome Registry of AnaLgesic Effect of SCS(MORALES) Registry Protocol
The objective is to provide information to help the physician community decide the most effective type of device/therapy that would work for their patients, based off of the etiology of pain, the location of the pain for…
- Trial name
- NCT04548375
- Testing
- SCS
- Where
- United States
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Cardio Surgical Partners
Surgery
Analgesic Efficacy of Us Guided Fascia Iliaca Block Versus Caudal Block in Pediatric Graft Surgeries
The study is aimed to determine which of the two methods , either the fascia iliaca block or the caudal block is better in managing the post operative pain and by which decreasing the consumption of analgesic drugs post…
- Trial name
- NCT06427174
- Testing
- Fascia iliaca block, Caudal block
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Assiut University
Pain
Genetic Basis For Variation In NSAID Analgesia In A Clinical Model Of Acute Pain
This study will evaluate how genetic makeup contributes to the variation in people regarding their sensitivity to and experience of pain.
- Trial name
- NCT00115752
- Testing
- Valdecoxib, COX Inhibitor
- Where
- United States
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- National Institute of Nursing Research (NINR)
Post Operative Pain
Analgesic Efficacy of Genicular Nerve Block Versus (IPack Block ) in Patients Undergoing (ACL) Repair
One of the most common injuries to the knee is an anterior cruciate ligament (ACL) sprain or tear due to trauma ACL damage is crippling and often requires repair with an arthroscopic method, which is an outpatient surgery.
- Trial name
- NCT06404658
- Testing
- Genicular nerve block
- Where
- Egypt
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Beni-Suef University
Anesthesia, Local
Dexmedetomidine as an Adjuvant to Local Anesthesia in Quadratus Lumborum Block After Cesarean Delivery
Postoperative pain is considered one of the major problems after abdominal operations, so proper pain control is one of the main issues in clinical practice.
- Trial name
- NCT04748224
- Testing
- Bupivacaine 0.25% Injectable Solution, bupivacaine plus dexmedetomidine
- Where
- 2 sites in Egypt
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Cairo University
Gonad Regulating Hormone Adverse Reaction, Analgesic Adverse Reaction
Neurobehavioral Development in Toddlers and Preschoolers in Relation to Prenatal Exposure of Mild Analgesics (NeuroToP - a COPANA Follow up)
Fundamental aspects of both neurological and reproductive function are established in fetal life, and there is a present increased awareness of the potential effects of fetal exposures on neurodevelopmental and reproductive…
- Conditions
- Gonad Regulating Hormone Adverse Reaction, Analgesic Adverse Reaction, Developmental Disability, Adhd
- Trial name
- NeuroToP (NCT07316387)
- Where
- Denmark
- Volunteers
- 685 people, healthy volunteers welcome
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Hysterosalpingography, Anxiety
The Effect of Using Music and Natural Landscape Paintings on Pain Level, Anxiety and Analgesic Use of Women During HSG
The study was planned as a randomized controlled study in order to evaluate the use of music and natural scenery paintings in women who underwent HSG procedure, their pain level, anxiety and post-procedure analgesic use.
- Conditions
- Hysterosalpingography, Anxiety, Pain
- Trial name
- NCT05712954
- Testing
- music group, video group
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- ŞERİVAN KARAKUT
Cleft Palate Children
Length of Hospital Stay and Postoperative Analgesic Requirements After Introduction of a Specific Maxillary Nerve Block in Children Undergoing Cleft Palate Surgery
Cleft lip and palate (CLP) is one of the most common congenital malformations and requires repeated surgical correction during childhood.
- Trial name
- NCT07279883
- Where
- Sweden
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Karolinska Institutet