Clinical trials: Anatomical Pathological Condition
Chronic Rhinosinusitis With Nasal Polyps (CRSwNP)
China CRSwNP Registry Study
Chronic rhinosinusitis with nasal polyps (CRSwNP) is a long-lasting inflammatory disease of the nose and sinuses that can cause nasal blockage, loss of smell, nasal discharge, facial discomfort, sleep problems, and reduced…
- Trial name
- POLARIS (NCT07795658)
- Testing
- Routine Clinical Care for CRSwNP
- Where
- China
- Volunteers
- 1,000 people
- Sponsor
- Beijing Tongren Hospital
Uterine Fibroid, Uterine Bleeding
4K Versus 3D Laparoscopic Colporraphy by Surgeons in Training: a Prospective Randomized Trial
This prospective randomized trial aims to assess if the operative time of vaginal cuff suture performed by trainees could be reduced using 3D laparoscopy instead of 4K laparoscopy.
- Conditions
- Uterine Fibroid, Uterine Bleeding, Uterine Prolapse
- Trial name
- NCT04637022
- Where
- Italy
- Volunteers
- 50 people
- Sponsor
- Catholic University of the Sacred Heart
Hernia, Ventral
Small Versus Large Bite Closure of Emergency Midline Laparotomy
In daily practice, midline laparotomy is an incision frequently performed by surgeons to achieve a rapid and wide access to the abdomen.
- Trial name
- E-STITCH (NCT04098380)
- Testing
- Small Bite, Larger bite
- Where
- Egypt
- Volunteers
- 160 people
- Sponsor
- Mansoura University
Inguinal Hernia
The Efficacy of Transversalis Fascia Plane Block in Pediatric Inguinal Hernia Repair
In patients undergoing lower abdominal surgery, postoperative pain management is frequently provided with systemic opioids use or neuraxial methods.
- Trial name
- NCT04272320
- Testing
- Bupivacaine Hydrochloride
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Ataturk University
Inguinal Hernia
Effectiveness of Topical Antibiotic Prophylaxis in Inguinal Hernia Repair
Aim of this study is to measure the effectiveness of topical gentamicin to prevent post-operative infection in inguinal tension-free hernia repair operation.Secondary aim is, if it is effective as a prophylactic agent, to compare…
- Trial name
- NCT01273818
- Testing
- Gentamicin and cefazolin, Cefazolin, Gentamicin
- Where
- Turkey (Türkiye)
- Volunteers
- 276 people
- Sponsor
- Diskapi Teaching and Research Hospital
Vaginal Fistula, Vesico Vaginal Fistula
Feasibility of the Menstrual Cup for VVF
This study examines the feasibility and acceptability of the vaginal menstrual cup for short-term management of vesicovaginal fistula (VVF) among 11 women seeking treatment at a health facility in Ghana.
- Conditions
- Vaginal Fistula, Vesico Vaginal Fistula, Obstetric; Injury
- Trial name
- FMCVVF (NCT03414060)
- Testing
- Menstrual Cup
- Where
- Ghana
- Volunteers
- 11 people
- Sponsor
- University of Ghana Medical School
Indirect Inguinal Hernia, Genetic Predisposition to Disease
Gene Expression and DNA Variation Analysis of Sacs to Identify the Pathophysiology of Indirect Inguinal Hernia
The aim of the project is to show that gene expression levels change in at least one of the GATA6 and T-box transcription factor 3 (TBX3) genes in indirect inguinal hernia sacs, thus revealing that this pathway causes an error in…
- Trial name
- NCT04634032
- Testing
- mRNA expression and SNP analysis, Blood sampling
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Trakya University
Umbilical Hernia
Analgesic Efficacy After Umbilical Hernia Repair in Children
Umbilical hernia repair is a common painful outpatient procedure performed in children. Often analgesia for this procedure is provided by using local infiltration of the surgical site by the surgeons and perioperative opioids and…
- Trial name
- NCT00578136
- Testing
- Bupivacaine
- Where
- United States
- Volunteers
- 52 people
- Sponsor
- Children's Hospital of Philadelphia
Alopecia Scar
Treatment of Alopecic Scars by Follicular Unit Extraction Hair Transplantation
This study aim: is to completely hide the alopecic scars in a way that it will not be visible.
- Trial name
- NCT06145672
- Testing
- follicular unit extraction and implantaion
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Assiut University
Hernia, Diaphragmatic
Early Childhood Follow-up of Congenital Diaphragmatic Hernia Survivors
The primary objective of this study is to determine the medical and neurodevelopmental outcomes of congenital diaphragmatic hernia (CDH) survivors at school-age (4-6 years) follow-up.
- Trial name
- CDH (NCT01029665)
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- Duke University
Dental Plaque, Gingivitis
Effectiveness of Toothbrushing Habits of Preschool Children, With or Without a Toothbrushing Assisting Application
The aim of this study is to investigate the effectiveness of the use of a toothbrushing assisting mobile application in dental plaque removal and adherence to the toothbrushing routine, in preschool children (3-5 yrs old) when…
- Trial name
- NCT05788692
- Testing
- electric tootbrush, manual toothbrush, toothbrushing assisting application
- Where
- 6 sites in Greece
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- National and Kapodistrian University of Athens
Keratoconus, Ectasia
UVA-Riboflavin Crosslinking Treatment of Corneal Ectasia
The primary objective of this study is to evaluate two different ultraviolet (UV) dosing regimens for corneal collagen cross linking to slow the progressive changes in corneal curvature in eyes with progressive keratoconus or…
- Conditions
- Keratoconus, Ectasia, Corneal Ectasia
- Trial name
- NCT01325298
- Testing
- UV-X Light, Riboflavin
- Where
- United States
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Mercy Center for Corrective Eye Surgery
Telogen Effluvium
Efficacy and Safety of Millet Seed Extract in Telogen Effluvium Treatment
This is a randomized, double-blind, controlled clinical trial investigating the efficacy and safety of millet seed extract capsules in treating telogen effluvium in female patients.
- Trial name
- NCT07348120
- Testing
- Millet Seed Extract group, Biotin group
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Kasr El Aini Hospital
Congenital Diaphragmatic Hernia
Microbiome and Volatile Organic Compounds in Patients With CDH
Despite improved prenatal diagnostics and therapeutic possibilities, congenital diaphragmatic hernia (CDH) represents a cross-disciplinary challenge.
- Trial name
- CDHVOCS (NCT03787160)
- Testing
- initial VOC, initial fecal microbiome, initial pulmonary microbiome
- Where
- Austria
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Medical University of Graz
Congenital Solitary Kidney
Long Term Outcome of Congenital Solitary Kidney
Congenital solitary kidney (CSK) is a disorder caused by an abnormal development of one of the two kidneys. The reported incidence ranges between 1:450-3200. It is debated whether CSK is a benign condition or not.
- Trial name
- CSKP (NCT01831141)
- Where
- Italy
- Volunteers
- 120 people
- Sponsor
- IRCCS Azienda Ospedaliero-Universitaria di Bologna
Bone Sarcoma, Soft Tissue Sarcoma
Preoperative Immunonutrition in Patients With Bone and Soft Tissue Sarcomas
This study will evaluate whether a short nutritional intervention before surgery can improve recovery in patients with bone and soft tissue sarcomas.
- Conditions
- Bone Sarcoma, Soft Tissue Sarcoma, Sarcopenia, Malnutrition
- Trial name
- NCT07609329
- Testing
- Forticare Advanced oral nutritional supplement
- Where
- Czechia
- Volunteers
- 100 people
- Sponsor
- St. Anne's University Hospital Brno, Czech Republic
Stricture Ureter
Buccal Mucosal Graft for Onlay Ureteroplasty in the Management of Proximal Ureteral Stricture
Onlay uretroplasty with either grafts or flaps has been attempted by many reconstructive urologists, ln particular buccal mucosa graft (BMG) ureteroplasty has been reported by many centers and has shown its feasibility and safety
- Trial name
- NCT05928364
- Testing
- Buccal mucosa for proximal ureter stricture
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Al-Azhar University
Uterine Fibroid, Uterine Bleeding
Can 3D Laparoscopy Improve Surgical Performances in Surgeons in Training?
Due to the inconclusive results on the benefits of 3D laparoscopic system present in literature, this prospective randomised pilot study aims to assess if the operative time of total laparoscopic hysterectomy (TLH) for benign…
- Conditions
- Uterine Fibroid, Uterine Bleeding, Uterine Prolapse
- Trial name
- NCT04209036
- Testing
- 0° 3D laparoscopy high-definition camera(Olympus Winter & IBE GMBH, Hamburg - Germany)
- Where
- Italy
- Volunteers
- 22 people
- Sponsor
- Catholic University of the Sacred Heart
Hemolytic Disorders, Gallstones
The Role of Ursodeoxycholic Acid in Treatment of Gallstones in Hemolytic Disorders
It is well established that hemolytic diseases predispose patients to the development of pigment gallstones. Gallstones are noted in at least 5% of children under the age of 10 years, increasing to 40-50% in the second to fifth…
- Trial name
- NCT02472509
- Testing
- Ursodeoxycholic Acid
- Where
- Israel
- Volunteers
- 3 people
- Sponsor
- Shaare Zedek Medical Center
Postoperative Agitation: Impaired Awareness, Abnormal Cognitive Function, Confusion, and Verbal and Physical Agitation During Recovery From General Anesthesia, Deviated Nasal Septum
Anterior Ethmoidal Nerve Block in Prevention of Postoperative Agitation
Postoperative agitation is an important complication of general anesthesia, moreover, it has been found with high incidence in ear, nose, throat (ENT) surgeries.
- Conditions
- Postoperative Agitation: Impaired Awareness, Abnormal Cognitive Function, Confusion, and Verbal and Physical Agitation During Recovery From General Anesthesia, Deviated Nasal Septum, Chronic Rhinosinusitis (Diagnosis), Nasal Polyps
- Trial name
- NCT03427502
- Testing
- Bupivacaine-epinephrine, normal saline
- Where
- Nepal
- Volunteers
- 100 people
- Sponsor
- Lumbini Medical College