Clinical trials: Anatomical Pathological Condition
Gall Stone
Colonic Gallstone Ileus, Diagnostic-therapeutic Algorithm
Gallstone ileus is a rare complication of gallstone disease. There is no systematic review on CGI. We analyze published literature on the subject and plan to propose a diagnostic-therapeutic algorithm for CGI.
- Trial name
- NCT04961411
- Testing
- operation or non-operative treatment
- Where
- Croatia
- Volunteers
- 113 people
- Sponsor
- Tomislav Bruketa
Abdominal Hernia, Abdominal Wall Defect
To Investigate the Use of a New Syringe "Visual Pressure Control (VPC)" for Epidural Anesthesia in Children Surgery
Pediatric epidural anesthesia has emerged as a safe and effective regional anesthesia technique for providing intraoperative and postoperative analgesia in thoracic and abdominal surgery.
- Conditions
- Abdominal Hernia, Abdominal Wall Defect, Abdominal Neoplasm, Urogenital Disease
- Trial name
- NCT05308771
- Testing
- VPC syringe
- Where
- Belgium
- Volunteers
- 15 people
- Sponsor
- Centre Hospitalier Universitaire de Tivoli
Kidney Stone, Nephrolithiasis
Pediatric KIDney Stone (PKIDS) Care Improvement Network
The goals of this study are to improve the ability of pediatric patients and their caregivers to select surgical treatment options for kidney stones and to enable urologists to use techniques that result in the best outcomes for…
- Trial name
- PKIDS (NCT04285658)
- Testing
- Ureteroscopy, Percutaneous Nephrolithotomy, Shock Wave Lithotripsy
- Where
- 31 sites in United States, Canada
- Volunteers
- 1,290 people
- Sponsor
- Children's Hospital of Philadelphia
Obstetric Fistula, Fistula
Effectiveness and Acceptability of Insertable Devices for Obstetric Fistula Management
The investigators propose a clinical trial and nested qualitative study to 1) quantify the effectiveness of an insertable vaginal cup to manage fistula urinary incontinence, 2) examine user and implementer acceptability, and 3)…
- Conditions
- Obstetric Fistula, Fistula, Fistula, Urinary, Fistula, Vaginal
- Trial name
- COPE (NCT05444504)
- Testing
- Cup, Cup+
- Where
- 3 sites in Ghana, Kenya
- Volunteers
- 100 people
- Sponsor
- University of California, San Francisco
Thymidine Kinase 2 Deficiency
A Study of the Efficacy and Safety of MT1621 in Thymidine Kinase 2 (TK2) Deficiency (Treatment naïve)
This is a Phase 3b, prospective, single-arm, multicenter, open-label treatment study of the efficacy and safety of MT1621 in pediatric and adolescent patients with thymidine kinase 2 deficiency (TK2d).
- Trial name
- NCT04581733
- Testing
- MT1621
- Sponsor
- Zogenix MDS, Inc.
Bladder Stone
Percutaneous Versus Transurethral Cystolithotripsy For The Management Of Bladder Calculi In The Pre-school Boys
Bladder stones are an uncommon condition in children, accounting for only 5% of urolithiasis in developed countries, whereas in developing nations, a greater number of children are affected due to the high incidence of urinary…
- Trial name
- NCT06970587
- Testing
- percutaneous cystolithotripsy
- Where
- Egypt
- Volunteers
- 150 people
- Sponsor
- South Valley University
Hernia, Inguinal
Outcome of Laparoscopic Inguinal Herniorraphy in Children
The investigators plan a retrospective, single-center outcome analysis of laparoscopic hernia repair in children operated between March 2nd, 2010, and March 1st, 2014.
- Trial name
- NCT02310958
- Testing
- Laparoscopic surgical hernia repair
- Volunteers
- 250 people
- Sponsor
- Johannes Mayr
Muscle-Invasive Bladder Carcinoma, Urothelial Carcinoma (UC)
Immune-Stromal Landscape in Muscle-Invasive Bladder Cancer
Bladder cancer is a significant global health issue. When the cancer spreads into the muscle layer of the bladder (muscle-invasive bladder cancer), a common treatment is the surgical removal of the bladder (radical cystectomy).
- Conditions
- Muscle-Invasive Bladder Carcinoma, Urothelial Carcinoma (UC), Bladder Cancer, Muscle-Invasive Urothelial Bladder Carcinoma
- Trial name
- NCT07525349
- Volunteers
- 100 people
- Sponsor
- Assiut University
Pelvic Organ Prolapse
Three-dimensional Ultrasound Assessment in Cases of Prolapse Surgeries
The levator ani muscle seems to play a key role in pelvic floor dysfunction. This muscle has two major components, the pubovisceral (including the pubococcygeus and puborectalis muscles) and the iliococcygeal muscles.Major…
- Trial name
- NCT03857724
- Testing
- prolapse surgery
- Where
- Egypt
- Volunteers
- 1 people
- Sponsor
- Assiut University
Leg Length Inequality, Cerebral Palsy
Spine Biomechanics During Gait Following Lower Extremity Treatment in Different Patient Groups
Measuring spine dynamics is a necessity in order to better understand gait deviations throughout the whole body and to evaluate treatment effects on spinal movement during gait.
- Trial name
- NCT01803243
- Testing
- Ankle foot orthosis, Shoe insole, Modified shoe with sole lift
- Where
- Switzerland
- Volunteers
- 20 people
- Sponsor
- University Children's Hospital Basel
Internal Hemorrhoid, Rectal Prolapse
CAES for Internal Hemorrhoids and Rectal Prolapse
Cap-assisted endoscopic sclerotherapy (CAES) is a new interventional therapy for internal hemorrhoids and rectal prolapse under colonoscopy.
- Trial name
- NCT04169152
- Testing
- Cap-assisted endoscopic sclerotherapy
- Where
- China
- Volunteers
- 10,000 people
- Sponsor
- Faming Zhang
Salivary Gland Stone, Salivary Gland Diseases
Evaluation of the Effect of Minimally Invasive Procedures Used in Management of Salivary Ductal Pathologies on Patients' Symptomatology and Gland Function
Aim of the current study was to evaluate the minimally invasive techniques in the management of salivary gland ductal pathologies
- Trial name
- NCT05346341
- Testing
- Minimally invasive techniques
- Where
- Egypt
- Volunteers
- 31 people
- Sponsor
- Aya Sakr
Stone, Kidney, Stone Ureter
Virtual Reality for Pain Control During Extracorporeal Shock Wave Lithotripsy: a Prospective, Comparative, Randomized Study at a Single Institution
The aim of this study is to prospectively analyze patient satisfaction, pain, delivered energy and clinical effectiveness of using VR as a complimentary treatment modality during SWL.
- Trial name
- NCT05183269
- Testing
- Oncomfort virtual reality monitor (Oncomfort SA, Wavre, Belgium)
- Where
- Belgium
- Volunteers
- 166 people, healthy volunteers welcome
- Sponsor
- AZ Sint-Lucas Gent
Tuberous Sclerosis, Angiofibroma
Long-term Trial of Topical Sirolimus to Angiofibroma in Patient With Tuberous Sclerosis Complex
The purpose of this trial is to evaluate the safety and efficacy of long-term treatment with NPC-12G gel (0.2% sirolimus gel) to angiofibroma and other skin lesions in patients with tuberous sclerosis complex in the open-label…
- Conditions
- Tuberous Sclerosis, Angiofibroma, Hypomelanotic Macule, Plaque
- Trial name
- NCT02634931
- Testing
- NPC-12G gel
- Where
- Japan
- Volunteers
- 94 people
- Sponsor
- Nobelpharma
Sarcopenia, Ultrasound
Assessment System for Sarcopenia Based on Ultrasonographic Data
1. To develop an artificial intelligence assisted diagnostic model for sarcopenia based on ultrasound images; 2. To develop artificial intelligence classification and regression models for auxiliary diagnosis of sarcopenia…
- Trial name
- NCT06199856
- Testing
- ultrasound scan
- Where
- China
- Volunteers
- 1,500 people, healthy volunteers welcome
- Sponsor
- West China Hospital
Pancreatic Cancer, Bile Duct Cancer
Randomized Controlled Trial on Pancreatic Stent Tube in Pancreaticoduodenectomy
The purpose of this study is to determine which stent type is effective in the decrease of postoperative stay and complications across pancreaticojejunostomy after pancreaticoduodenectomy.
- Conditions
- Pancreatic Cancer, Bile Duct Cancer, Ampullary Cancer, Pancreatitis
- Trial name
- NCT00628186
- Testing
- external drainage tube [polyethylene pancreatic drainage tube], internal drainage tube [polyethylene pancreatic drainage tube]
- Where
- Japan
- Volunteers
- 100 people
- Sponsor
- Wakayama Medical University
Pancreaticoduodenectomy, Distal Pancreatectomy
Randomized Trial of Early Versus Standard Drainage Removal After Pancreatic Resections
Despite a substantial decrease in postoperative mortality, morbidity after pancreatic resections is still high, even at high-volume centers.
- Conditions
- Pancreaticoduodenectomy, Distal Pancreatectomy, Pancreatic Fistula, Abdominal Abscess
- Trial name
- NCT00931554
- Testing
- Postoperative drain removal
- Where
- Italy
- Volunteers
- 114 people
- Sponsor
- Universita di Verona
Colorectal Neoplasms
Third Eye Panoramic Device Feasibility Evaluation
This study will evaluate the feasibility of using the Third Eye Panoramic device in conjunction with standard colonoscopes in a clinical setting.
- Trial name
- NCT02368977
- Testing
- Third Eye Panoramic device
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Avantis Medical Systems
Edentulous; Alveolar Process, Atrophy
Osseodensification Drills Versus Piezoelectric Surgery
implant stability is the first requirement for implant success. the aim is to assess whether different implant site preparation technique may impact the value of the primary stability.
- Trial name
- NCT05410405
- Testing
- implant site preparation
- Where
- 2 sites in Italy
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- International Piezosurgery Academy
Caries
Effectiveness of Toothbrushing Techniques in Plaque Removal and Caries Lesion Control
The aim of the study is to evaluate the effectiveness of cross-toothbrushing technique compared with anteroposterior and biofilm removal and control of caries lesions in first permanent molars.
- Trial name
- toothbrushing (NCT01501357)
- Testing
- modified toothbrush with multilevel filaments, cross toothbrushing
- Where
- Brazil
- Volunteers
- 220 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo