Clinical trials: Anemia (Iron-Loading)
Beta Thalassemia Major
An Algorithm to Start Iron Chelation in Minimally Transfused Young Beta-thalassemia Major Patients
A prospective randomized study on Safety, Tolerability and Efficacy of oral Low dose DFP (50 mg/kg/day) in minimally transfused B-TM after 5 transfusions when SF reaches 500 ng/m and with either appearance of LPI > 0.2 or TSAT…
- Trial name
- NCT02173951
- Testing
- Deferiprone
- Where
- Egypt
- Volunteers
- 64 people
- Sponsor
- Ain Shams University
Sickle Cell Disease
A 3-year, Prospective, Non-interventional, Multicenter Registry in Sickle Cell Disease (SCD) Patients
A long term observational study in sickle cell disease will enhance the understanding of the disease patterns, current transfusion practices, treatments and outcomes in sickle cell disease.
- Trial name
- FISCO (NCT01220115)
- Where
- 42 sites in United States
- Volunteers
- 498 people
- Sponsor
- Novartis
THALASSEMIA MAJOR
Reproductive Capacity and Iron Burden in Thalassemia
The improved long-term survival of thalassemia major (TM) patients has resulted in increased focus on the ability to preserve fertility.
- Trial name
- Fertility thal (NCT02308904)
- Testing
- Blood Draw/Semen Exam, Retrospective data/Chart Review/Relevant Clinical Results, Pituitary MRI
- Where
- United States
- Volunteers
- 59 people, healthy volunteers welcome
- Sponsor
- UCSF Benioff Children's Hospital Oakland
Sickle Cell Disease, Thalassemia
Multi-Center Study of Iron Overload: Pilot Study
The purpose of this study is to initiate pilot studies to demonstrate that a sufficient number of iron-overloaded thalassemia, SCD and DBA populations with similar duration of chronic transfusion, and age at start of transfusions…
- Conditions
- Sickle Cell Disease, Thalassemia, Diamond-Blackfan Anemia
- Trial name
- MCSIO (NCT01114776)
- Where
- 3 sites in United States, Germany and 1 more
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- UCSF Benioff Children's Hospital Oakland
Anemia (Iron-Loading), Beta-Thalassemia
Evaluation of Subcutaneous Desferrioxamine as Treatment for Transfusional Hemochromatosis
To determine whether deferoxamine prevented the complications of transfusional iron overload.
- Conditions
- Anemia (Iron-Loading), Beta-Thalassemia, Hematologic Diseases, Hemoglobinopathies
- Trial name
- NCT00000595
- Testing
- deferoxamine
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)