Clinical trials: Anesthesia, Endotracheal
Airway Management, Intubation, Intratracheal
The Difficult Airway Management Trial: "The DIFFICAIR-Trial"
In general anesthetic the patient is deprived of his awareness and ability to breathe. It is therefore one of the most important tasks in anesthesia to ensure the patient's airway and breathing.
- Trial name
- DIFFICAIR (NCT01718561)
- Testing
- SARI
- Where
- 28 sites in Denmark
- Volunteers
- 76,058 people, healthy volunteers welcome
- Sponsor
- Hillerod Hospital, Denmark
Endotracheal Tube, Finger
Correlation Between Anthropometric Characteristics and Age-based Formulas for Uncuffed Pediatric Endotracheal Tube
The goal of this observational study is to investigate the correlation between anthropometric characteristics, such as finger circumferences, body weight, body height, and body mass index, and age-based formulas for uncuffed tube…
- Trial name
- NCT07349953
- Where
- Serbia
- Volunteers
- 103 people, healthy volunteers welcome
- Sponsor
- Mother and Child Health Institute of Serbia Dr Vukan Cupic
Coughing Responses at Tracheal Extubation, Breathing Patterns
Endotracheal Tube Intolerance and Respiratory Airflow Perception
This is a case-control study designed to enroll 224 patients who will undergo tracheal intubation for general anesthesia in the operating rooms of Peking University People's Hospital between July 20, 2026, and October 31, 2026.
- Trial name
- NCT07759284
- Volunteers
- 224 people, healthy volunteers welcome
- Sponsor
- Peking University People's Hospital
Elective Urological Surgery
New Formula for Selection of Proper Size of Endotracheal Tube (ETT) in Children: Ultrasonographic Examination
Choosing the adequate size of endotracheal tube(ETT) in pediatric patients is important in all anesthesiologists, pediatricians, and critical care specialists.
- Trial name
- NCT01227161
- Where
- South Korea
- Volunteers
- 215 people, healthy volunteers welcome
- Sponsor
- Yonsei University
Appendicitis Acute, Postoperative Sore Throat, Cough, Hoarseness
Effect of Endotracheal Tube Cuff Pressure Management on Postoperative Sore Throat in Pediatric Laparoscopic Appendectomy
Abstract Objective: The aim of this study is to compare two different ways of adjusting the air-filled cushion (cuff) of the breathing tube used during general anesthesia in children undergoing laparoscopic appendectomy (closed…
- Conditions
- Appendicitis Acute, Postoperative Sore Throat, Cough, Hoarseness, Airway Complications, Respiratory Complications
- Trial name
- NCT07678086
- Testing
- Pressure Transducer, Traditional Palpation Method
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Ankara Etlik City Hospital
Anesthesia, Endotracheal
A Comparison of McGrath MAC Videolaryngoscopy and Macintosh Laryngoscopy for Orotracheal Intubation in Children With Torticollis
The primary purpose of this study is to investigate the effects of McGrath MAC videolaryngoscopy on the intubation time for orotracheal intubation in children with torticollis.
- Trial name
- NCT03582787
- Testing
- McGrath MAC videolaryngoscopy, Macintosh Laryngoscopy
- Where
- South Korea
- Volunteers
- 30 people
- Sponsor
- Ajou University School of Medicine
Respiratory Failure, Cardiac Arrest
'Single Hand Used inTubaTing Laryngoscope Evaluation' Study
This is a study to compare the new ShuttleScope with the standard Macintosh Laryngoscope
- Conditions
- Respiratory Failure, Cardiac Arrest, Difficult Intubation, Anesthesia Intubation Complication
- Trial name
- SHUTTLE (NCT04310384)
- Testing
- ShuttleScope, MacIntosh Laryngoscope
- Where
- Spain
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of the Basque Country (UPV/EHU)
Hemodynamic Instability
Role of Nebulized Dexmedetomidine in Blunting the Effects of Direct Laryngoscopy and Endotracheal Tube on Heart Rate and Blood Pressure.
The goal of this interventional study is to check the effectiveness of nebulized Dexmedetomidine in preventing the rise in blood pressure and heart rate in patients undergoing General Anesthesia.
- Trial name
- NCT06103721
- Testing
- Dexmedetomidine Injection [Precedex], Normal Saline
- Where
- Pakistan
- Volunteers
- 126 people, healthy volunteers welcome
- Sponsor
- Muhammad Haroon Anwar
Predicting Uncuffed Endotracheal Tube Size in Pediatric Anesthesia
Comparison of Modified Broselow Tape and Cole Formula
This study aimed to determine the accuracy of modified Broselow tape measurements compared to Cole formula in predicting the size of uncuffed endotracheal tubes in Indonesian pediatrics
- Trial name
- NCT04869410
- Testing
- Modification Broselow Tape, Cole Formula
- Where
- Indonesia
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Universitas Indonesia
Endotracheal Extubation, Airway Anesthesia
BELUGA: Better to Exchange ETT for LMA Before Extubation in Children Under General Anaesthesia
During surgery, anaesthetists can use an endotracheal tube (ETT) to facilitate ventilation. At emergence from general anaesthesia, there are two techniques for removal of the ETT: (1) the ETT is removed when the child is waking…
- Conditions
- Endotracheal Extubation, Airway Anesthesia, Paediatric
- Trial name
- BELUGA (NCT07204990)
- Testing
- Direct removal of endotracheal tube, Laryngeal mask airway inserted following deep extubation
- Where
- 8 sites in United States, Australia and 4 more
- Volunteers
- 1,400 people
- Sponsor
- Telethon Kids Institute
Gastric Cancer, Hepatic Carcinoma
Laryngopharyngeal Injury After Endotracheal Intubation Under General Anesthesia
This study retrospectively analyzed patients who underwent tracheal intubation under general anesthesia at the First Affiliated Hospital of Zhejiang University School of Medicine between October 1, 2015, and September 30, 2025…
- Conditions
- Gastric Cancer, Hepatic Carcinoma, Pulmonary Carcinoma, Pancreatic Carcinoma
- Trial name
- NCT07359586
- Where
- 2 sites in China
- Volunteers
- 1,200 people
- Sponsor
- Zhejiang University
Optic Nerve Sheath Diameter, Pediatric Anesthesia
Comparison of the Effects of Endotracheal Intubation and Laryngeal Mask Applications on Optic Nerve Diameter in Pediatric Patients
This clinical study aims to investigate the effects of breathing tubes - used to connect children aged 1-11 to a respiratory device under general anesthesia in the operating room - on intracranial pressure after they are…
- Conditions
- Optic Nerve Sheath Diameter, Pediatric Anesthesia, Intubation, Laryngeal Mask Airways
- Trial name
- NCT06994481
- Testing
- optic nerve sheet diameter measurement
- Where
- Turkey (Türkiye)
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Marmara University Pendik Training and Research Hospital
Endotracheal Intubation, Gastrointestinal Endoscopy
Application of Lateral Position Digestive Endoscopy-Guided Endotracheal Intubation in Anesthesia for Endoscopic Diagnosis and Therapy
This case series study evaluated whether placing a breathing tube using a camera (gastrointestinal endoscope) is safe and effective for patients lying on their left side during stomach and intestine exams under anesthesia.
- Conditions
- Endotracheal Intubation, Gastrointestinal Endoscopy, Airway Management, Lateral Position
- Trial name
- NCT06990490
- Where
- China
- Volunteers
- 40 people
- Sponsor
- Changlong Qiao
Anesthesia, Endotracheal
A Comparison of McGrath MAC Videolaryngoscopy and Macintosh Laryngoscopy for Orotracheal Intubation in Children
The primary purpose of this study is to investigate the effects of McGrath MAC videolaryngoscopy on the intubation time for orotracheal intubation in children.
- Trial name
- NCT02827123
- Testing
- McGrath MAC videolaryngoscopy, Macintosh Laryngoscopy
- Where
- South Korea
- Volunteers
- 84 people
- Sponsor
- Ajou University School of Medicine
Surgery, Anesthesia, Endotracheal
The Videolaryngoscopy in Small Infants
Complications related to infant (≤ 1 year) airway management are under-appreciated because of few rigorous and targeted studies.
- Trial name
- VISI (NCT03396432)
- Testing
- Video Laryngoscopy for ET placement, Direct Laryngoscopy for ET Placement
- Where
- 5 sites in United States, Australia
- Volunteers
- 566 people
- Sponsor
- Children's Hospital of Philadelphia
Endotracheal Tube Wrongly Placed During Anesthetic Procedure
Video Laryngoscopy vs Direct Laryngoscopy in Paediatric Patients
The goal of this interventional study is to compare the effectiveness of direct laryngoscopy vs. video laryngoscopy in paediatric population aged 2 to 8 years presenting for elective surgeries having uncomplicated airways.
- Trial name
- NCT06436196
- Testing
- Video Laryngoscope, Direct laryngoscope
- Where
- Pakistan
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- Watim Medical & Dental College
Endotracheal Tube Placement
Electrical Impedance Tomography for Endotracheal Tube Placement
Endobronchial tube misplacement is serious complication during general anesthesia in pediatric patients. Correct placement of the endotracheal tube (ETT) in the trachea is crucial.
- Trial name
- NCT01237756
- Testing
- measurement of left and right lung ventilation
- Where
- Germany
- Volunteers
- 18 people
- Sponsor
- University Hospital Freiburg
Anesthesia Intubation Complication, Premature Birth of Newborn
Optimizing Propofol Dosing for (Preterm) Newborn Infants That Need Endotracheal Intubation
Newborns admitted to an intensive care unit often require artificial ventilation. For that purpose an endotracheal tube needs to be placed into the trachea, a procedure named endotracheal intubation.
- Conditions
- Anesthesia Intubation Complication, Premature Birth of Newborn, Other Preterm Infants, Propofol Overdose
- Trial name
- NEOPROP2 (NCT02040909)
- Testing
- Propofol
- Where
- 3 sites in Netherlands
- Volunteers
- 91 people
- Sponsor
- Erasmus Medical Center
Preterm Infant, Anesthesia
The Comparison of Laryngeal Mask Airway and Endotracheal Tube in General Anesthesia for Premature Neonates
Objectives: To compare the perioperative respiratory adverse events between using laryngeal mask airway and endotracheal tube in preterm neonates receiving general anesthesia for hernia surgery.
- Conditions
- Preterm Infant, Anesthesia, Respiratory Complication
- Trial name
- NCT03931902
- Testing
- intubation with Endotracheal tube, intubation with laryngeal mask airway
- Where
- Taiwan
- Volunteers
- 43 people
- Sponsor
- Kaohsiung Medical University Chung-Ho Memorial Hospital
Intratracheal, Dexmedetomidine
Effect of Intratracheal Dexmedetomidine Administration on Recovery From General Anesthesia in Pediatrics Undergoing Lower Abdominal Surgery:
The incidence of intratracheal tube-induced laryngeal irritation, including coughing, bucking, and cardiovascular stimulation, on emergence from general anesthesia has been reported to occur in 38% and 96% of cases.
- Trial name
- NCT04385602
- Testing
- Intratracheal dexmedetomidine, Saline Solution
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Assiut University