Clinical trials: Anesthesia, Local
Regional Anesthesia Morbidity, Hip Surgeries
Pericapsular Nerve Group Block vs. Fascia Iliaca Compartment Block vs. Caudal Block for Hip Surgeries
The study aims to compare the effect of pericapsular nerve group block versus fascia iliaca compartment block versus caudal block regarding Postoperative analgesia in children undergoing hip surgeries.
- Conditions
- Regional Anesthesia Morbidity, Hip Surgeries, Perioperative Analgesia
- Trial name
- NCT07137962
- Testing
- PENG Block, FICB Block, Caudal Block
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Cairo University
Dental Phobia, Dental Anxiety
Assessment of Pain, Anxiety and Efficiency of NumBee Compared to Traditional Local Anesthetic Syringe
The study was conducted among a group of dental patients aged (6-8 years old) of both genders to assess the following variables in the needleless interparliamentary anesthesia (NUMBEE) compared to traditional local anesthesia: 1.
- Conditions
- Dental Phobia, Dental Anxiety, Anesthesia, Local, Needle Phobia
- Trial name
- NCT05899296
- Testing
- dental syringe ( NumBee), Traditional dental syringe
- Where
- Iraq
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Duaa Kamal Naji
Dental Anxiety, Pain
Effectiveness of Hand/Eyes/Mouth Behavior Management Technique During Local Anesthesia in Preschool Children
This will be a randomized, controlled, parallel-group clinical trial. The aim of this studio will be to evaluate the effectiveness of "Hands/Eyes/mouth" behavior management technique versus a conventional technique (covering the…
- Conditions
- Dental Anxiety, Pain, Infant Behavior, Heart Rate and Rhythm Disorders
- Trial name
- NCT02591797
- Testing
- inferior alveolar and lingual nerve block procedure
- Where
- Spain
- Volunteers
- 52 people
- Sponsor
- Cardenal Herrera University
Anesthesia, Local
Comparing Analgesic Effects of Three Ultrasound Guided Regional Anesthetic Techniques in Pediatrics
This study evaluates analgesic effects of ultrasound-guided (USG) regional anesthetic techniques; caudal block , transversus abdominis plane (TAP) block and quadratus lumborum block (QLB) by comparing postoperative pain scores […
- Trial name
- NCT03780790
- Testing
- Bupivacaine
- Where
- Turkey (Türkiye)
- Volunteers
- 135 people
- Sponsor
- Istanbul University
Anesthesia, Local
Changes in Tissue Oxygenation Following Regional Anesthesia
Adequate tissue oxygenation is required for effective white blood cell function and bactericidal activity. Decreased tissue oxygenation is a risk factor for perioperative wound infections.
- Trial name
- NCT01418690
- Where
- United States
- Volunteers
- 29 people
- Sponsor
- Nationwide Children's Hospital
Pain, Anxiety
Local Anesthesia Pen vs Conventional Syringe In The Treatment of Pain and Dental Anxiety
The goal of this is to compare pain and anxiety that may occur during dental anesthesia delivery using conventional dental syringe and the dental anesthesia injector (wireless pain less pen in pediatric dentistry.
- Trial name
- NCT07656194
- Testing
- Dental anesthesia injector
- Where
- Saudi Arabia
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Shahad Abudawood
Surgery
Regional Anesthesia EMG Study
This study aims to investigate how non-invasive, non-significant risk EMG monitoring can be used intraoperatively to objectively characterize neuraxial anesthesia (i.e.
- Trial name
- NCT06287151
- Testing
- BlockSynop surface electromyography device, Clonidine, Sevoflurane
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Nationwide Children's Hospital
Pediatric Postoperative Pain
Postoperative Pain After Pediatric Umbilical Hernia Repair
The purpose of this study is to compare the use of ultrasound-guided bilateral rectus sheath blocks to local infiltration of anesthetic agent in the surgical wound in a pediatric population of patients undergoing umbilical hernia…
- Trial name
- NCT01015053
- Testing
- bilateral ultrasound-guided rectus sheath block, Wound infiltration
- Where
- 2 sites in United States
- Volunteers
- 53 people
- Sponsor
- Boston Children's Hospital
Spinal Anesthesia, Local Anesthetic
Age-Based and Weight-Based Bupivacaine Dosing for Pediatric Spinal Anesthesia for Elective Infra-Umbilical Surgeries
Pediatric anesthesia presents distinctive challenges, particularly concerning appropriate dosage administration of local anesthetics for spinal anesthesia (SA).
- Conditions
- Spinal Anesthesia, Local Anesthetic, Bupivacaine
- Trial name
- NCT06801600
- Testing
- Weight-based dosing, Age-based dosing
- Volunteers
- 60 people
- Sponsor
- Cairo University
Anesthesia, Local
Comparing the Hemodynamic Effects of Epinephrine Versus Dexmedetomidine as an Adjuvant to Bupivacaine in Caudal Anaesthesia Assessed by Cardiometry
Electrical cardiometry (EC) is a non-invasive method of estimating cardiac parameters by measuring changes in thoracic bioimpedance during the cardiac cycle.
- Trial name
- NCT05860010
- Testing
- Epinephrine injection, Dexmedetomidine, Bupivacaine
- Where
- 2 sites in Egypt
- Volunteers
- 39 people
- Sponsor
- Kasr El Aini Hospital
Dental Anesthesia, Sweet Taste Perception
Efficacy of Pre-cooling and Sweet-tasting Solution on Pain Related to Local Anesthesia Injection in Children
The study aims to determine whether pre-cooling and sweet-tasting solutions, alone or combined with topical anesthesia, provide better pain control during dental local anesthesia in children.
- Conditions
- Dental Anesthesia, Sweet Taste Perception, Pain and Anxiety, Behavioral Management
- Trial name
- NCT07835191
- Testing
- Dental anesthesia
- Where
- Egypt
- Volunteers
- 224 people
- Sponsor
- British University In Egypt
Anesthesia, Local
Pain Control of Needle-free Versus Needle Injected Local Anesthesia for Pulpotomy of Upper Primary Molars in Children
This is a study that will be conducted on 6 to 8 years old children to compare the needle-less jet injector with the conventional needle attached syringe in terms of efficiency in controlling pain of local anesthetic infiltration…
- Trial name
- NCT03917121
- Testing
- Jet injector, Needle attached dental syringe
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Cairo University
Male Circumcision, Regional Anesthesia
Pudendal Nerve Block vs Penile Nerve Block for Analgesia During Pediatric Circumcision
Pediatric circumcision has been realized since the beginning of human civilization. In the United States, a 2014 review revealed a 81% prevalence of men 14-59 years old being circumcised.
- Trial name
- NCT03914365
- Testing
- Ultrasound-guided pudendal nerve block (PNB) and Ultrasound-guided penile nerve block (DPNB)
- Where
- Canada
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- CHU de Quebec-Universite Laval
Local Anesthesia Infiltration
Efficacy of Facial Massager in Reducing Intra Oral Injection Pain in Pediatric Patients
Abstract Background: Local anesthesia is a primary source of anxiety in pediatric dentistry. Objective: To evaluate if mechanical vibration from a low-cost facial massager reduces pain and anxiety during injections using the Gate…
- Trial name
- NCT07682181
- Testing
- Facial T massager, Topical Benzocaine 20%
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Government Dental College and Hospital, India
Regional Anesthesia Morbidity, Gallbladder Stone
LaGRA Trial in Laparoscopic Cholecystectomy
This study investigated the effectiveness of a surgeon administered, laparoscopic guided, regional anaesthesia technique.
- Conditions
- Regional Anesthesia Morbidity, Gallbladder Stone, Pain
- Trial name
- LaGRA (NCT03394807)
- Testing
- Levobupivacaine
- Volunteers
- 76 people
- Sponsor
- Health Service Executive, Ireland
Pain, Postoperative
Combined Nerve Blockade and Local Infiltration Anesthesia in Appendectomy - A Blinded Randomized Study
The purpose of this study is to assess whether the use of local anesthetic to numb the nerves that run deeper in the abdominal wall gives better post operative pain control than just infiltrating local anesthetic to the wound…
- Trial name
- NCT00508092
- Testing
- local anesthetic administration
- Where
- United Kingdom
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Royal Berkshire NHS Foundation Trust
Anesthesia
Impact of Ultrasound in Obstetric Anesthesia Central Blocks
This study aimed to evaluate the use of ultrasound in obstetric anesthesia, specifically for measuring epidural and intrathecal distances in pregnant women undergoing cesarean section.
- Trial name
- NCT06761222
- Testing
- The use of ultrasound in central blocks
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Ege University
Injection Site Irritation, Injection Site Bruising
Comparison of Subcutaneous Injection of Normal Saline and Bacteriostatic Saline
This is a randomized, double-blind, single-center clinical trial comparing normal saline and bacteriostatic saline subcutaneous injection within a single subject.
- Conditions
- Injection Site Irritation, Injection Site Bruising, Injection Site Discomfort, Benzoic Acid Adverse Reaction
- Trial name
- NCT05109000
- Testing
- Sodium Chloride 0.9% Inj, Bacteriostatic Sodium Chloride 0.9 % INJECTION VIAL (ML)
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Jeffrey Alan Klein, MD
Dental Anxiety, Pain Management
Effectiveness of Virtual Reality Technique on Children
Studying the effect of using virtual reality technique in managing pain, anxiety, and vital signs among pediatric dental patients.
- Conditions
- Dental Anxiety, Pain Management, Pediatric Dentistry
- Trial name
- NCT07722221
- Testing
- Conventional, Virtual reality
- Where
- Syria
- Volunteers
- 64 people
- Sponsor
- Latakia University
Scoliosis, Spinal Deformity
Bilateral Bi-level Erector Spine Plane Block as a Component of General Anesthesia in Surgical Correction of Spinal Deformations
Improving the anesthesiology management for surgical correction of spinal deformations with introducing the diagnostic methods and treatment strategy of acute pain, preventing the evolution of chronic pain.
- Conditions
- Scoliosis, Spinal Deformity, Acute Pain, Chronic Pain
- Trial name
- BBESPB (NCT04697498)
- Testing
- Bilateral bi-level Erector spine plane block, General anaesthesia
- Where
- Ukraine
- Volunteers
- 150 people
- Sponsor
- Lviv National Medical University