Clinical trials: Anesthesia, Local
Molar-Incisor Hypomineralization
Evaluation of Different Anesthesias in Children With Molar Incisor Hypomineralization
In children with molar-incisor hypomineralization (MIH), insufficient depth of anesthesia can lead to increased anxiety and behavior management problems, which may negatively affect the quality of restorations.
- Trial name
- NCT07268157
- Testing
- Computer-controlled anesthesia device (SleeperOne), Conventional injection technique
- Where
- Turkey (Türkiye)
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Canan Bayraktar Nahir
Trigeminal Neuralgia
Regional Anesthesia in Refractory Trigeminal Neuralgia: 21 Cases Reported to the Limoges University Hospital
Trigeminal neuralgia is defined according to the third edition of the International Classification of Headache Disorders (ICHD-3) criteria. Chronic pain can have a major impact on the quality of life.
- Trial name
- TRINEB ONE (NCT03669744)
- Testing
- telephone survey
- Where
- France
- Volunteers
- 21 people
- Sponsor
- University Hospital, Limoges
Adductor Canal Block, Postoperative Pain
Comparison of Combination of Proximal ACB and iPACK With Large-Volume Distal ACB for Early Mobilization After TKR
Large-volume distal ACB is not superior to combination of proximal ACB and iPACK in facilitating early mobilization after TKR. Block performing time of distal ACB was significantly shorter compared to the combination of proximal…
- Conditions
- Adductor Canal Block, Postoperative Pain, Regional Anesthesia
- Trial name
- NCT06525493
- Testing
- Regional Anesthesia
- Where
- Indonesia
- Volunteers
- 30 people
- Sponsor
- Universitas Indonesia
Anesthesia, Local
PDL Anesthesia Versus Local Infiltration
The literature concerning the success and pain scores of PDL injection technique compared with other techniques remains controversial; whereas some studies found no significant difference in pain scores between local infiltration…
- Trial name
- PDL (NCT03173898)
- Testing
- PDL anesthesia versus local infiltration
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- University of Jordan
Injection Site Irritation, Injection Site Bruising
Comparison of Subcutaneous Injection of Normal Saline and Bacteriostatic Saline
This is a randomized, double-blind, single-center clinical trial comparing normal saline and bacteriostatic saline subcutaneous injection within a single subject.
- Conditions
- Injection Site Irritation, Injection Site Bruising, Injection Site Discomfort, Benzoic Acid Adverse Reaction
- Trial name
- NCT05109000
- Testing
- Sodium Chloride 0.9% Inj, Bacteriostatic Sodium Chloride 0.9 % INJECTION VIAL (ML)
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Jeffrey Alan Klein, MD
Anesthesia, Local
Efficiency of Single Buccal Infiltration Versus Buccal and Intrapapillary Infiltration
Everyday practice in dentistry is based on giving the painless injection and achieving adequate local anesthesia. Various techniques of reducing injection pain in children can be broadly categorized as psychological and physical.
- Trial name
- NCT04458142
- Testing
- Single buccal infiltration
- Volunteers
- 25 people
- Sponsor
- Cairo University
Keloid, Alopecia Areata
Pain Outcomes Following Intralesional Corticosteroid Injections
Corticosteroid therapy, including intralesional and topical applications, has many indications within the fields of Dermatology, Plastic Surgery, and Orthopedics.
- Conditions
- Keloid, Alopecia Areata, Acne, Hypertrophic Scar
- Trial name
- NCT03630198
- Testing
- Corticosteroid with lidocaine, Corticosteroid with normal saline
- Where
- United States
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- Vanderbilt University Medical Center
Peripheral Nerve Block, Post Operative Analgesia
Transversus Abdominis Plane Lock Versus Quadratus Lumborum Block in Children
Although abdominal wall surgeries are also as routinely performed on pediatric patients, postoperative pain in children has remained under-researched compared to adults.
- Conditions
- Peripheral Nerve Block, Post Operative Analgesia, Ultrasound-guided Regional Anesthesia
- Trial name
- NCT06861556
- Testing
- Ultrasound guided Transversus Abdominis Plane block with 0.2ml/kg bupivacaine 0.25%, Ultrasound-guided Quadratus Lumborum block with 0.2ml/kg bupivacaine 0.25%
- Where
- Tunisia
- Volunteers
- 90 people
- Sponsor
- Tunis University
Knee Osteoarthritis, Hip Osteoarthritis
Regional Anesthesia in Total Hip and Knee Arthroplasty
The purpose of this study is to test whether the use of Ropivacaine and Mepivacaine are better in terms of effectiveness, cost, and safety than Bupivacaine as regional anesthetics in elective hip or knee replacement surgery.
- Trial name
- NCT04257682
- Testing
- Bupivacaine, Ropivacaine, Mepivacaine
- Volunteers
- 135 people
- Sponsor
- Ottawa Hospital Research Institute
Orchiectomy, Spermatic Cord Block
Comparison of Spinal Anesthesia and Spermatic Cord Block for Bilateral Orchiectomy
The goal of this randomized controlled trial is to compare intraoperative pain score, Morphine consumption during 6 and 12 hour after surgery, and postoperative complications between SA and SCB groups in metastatic prostate…
- Conditions
- Orchiectomy, Spermatic Cord Block, Spinal Anesthesia, Pain Score
- Trial name
- NCT06313775
- Testing
- bilateral orchiectomy
- Where
- Thailand
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Sanpasitthiprasong Hospital
Regional Anesthesia
Exploring the Efficacy of Assistive Artificial Intelligence for Ultrasound Guided Regional Anesthesia in Residency Training
The purpose of this study is to investigate the efficacy of a novel artificial intelligence (AI) device designed to assist in Ultrasound guided regional anesthesia (ScanNav Anatomy Peripheral Nerve Block; ScanNav), in the…
- Trial name
- NCT06667401
- Testing
- The ScanNav, a novel artificial intelligence device designed to assist in Ultrasound guided regional anesthesia
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Medical College of Wisconsin
Dental Caries in Children, Anesthesia, Local
Efficacy of Ethyl Chloride Topical Anesthesia Application on the Pain Perception During Intra-oral Injections in Children in Comparison to Benzocaine Gel.
The goal of this single-blinded randomized controlled trial is to compare pain perception during buccal infiltration using indirect EC spray and topical anesthesia and BC 20% topical gel, among seven to 10-year-old school…
- Conditions
- Dental Caries in Children, Anesthesia, Local, Injection Site Discomfort
- Trial name
- NCT06011005
- Testing
- Ethyl Chloride spray (group A), Benzocaine gel 20% (group B)
- Where
- United Arab Emirates
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Mohammed Bin Rashid University of Medicine and Health Sciences
Child Behaviour
Comparison of a Needle-free Local Anesthetic Technique With Traditional Syringe [ Needle Syringe] Technique for the Restoration of Primary Molars and Permanent Molars
The goal of this clinical trial is to compare the effectiveness of needle free system and dental needle system [Traditional syringe system] for restoration of Primary and young permanent teeth.
- Trial name
- NCT06448507
- Testing
- INJEX [Needle less anesthesia], Syringe Needle [ Traditional technique]
- Where
- Saudi Arabia
- Volunteers
- 50 people
- Sponsor
- University of Jazan
Regional Anesthesia Morbidity
Comparison of Femoral Nerve Block Versus Fascia Iliaca Compartment Block for Pain Control in Traumatic Femur Fracture Repair in Pediatric Population
Pediatric orthopedic surgical procedures require a multimodal approach for anesthetic management that maximizes both patient comfort and safety.
- Trial name
- NCT05882201
- Testing
- Fascia Iliaca compartment block group, Femoral nerve block group, General care
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- Menoufia University
Hip Dislocation, Congenital, Postoperative Pain
Quadratus Lumborum Block for Pediatric Hip Surgery
Caudal blockade (CB) is one of the most frequently performed regional anaesthetic techniques in children. It's an efficient way to offer perioperative analgesia for painful sub-umbilical interventions but with high incidence of…
- Conditions
- Hip Dislocation, Congenital, Postoperative Pain, Anesthesia
- Trial name
- NCT04292782
- Testing
- anterior Quadratus lumborum block, caudal block
- Where
- Tunisia
- Volunteers
- 40 people
- Sponsor
- University Tunis El Manar
Anesthesia
Regional Anesthesia in Cardiac Pediatric Patients Less Than 5 Years Old
This retrospective review presents a comparison of pediatric patients less than 5 years old undergoing cardiac surgery with general anesthesia with spinal, caudal epidural, or caudal epidural with catheter anesthesia from July…
- Trial name
- NCT02652117
- Volunteers
- 545 people, healthy volunteers welcome
- Sponsor
- University of Iowa
Edentulous Jaw, Dental Implant
Comparing Two Anesthetic Techniques for Implant Placement
To evaluate in a comparative way the patient's perception in implant surgery in the posterior mandibular quadrants depending on whether the operation is performed under trunk anaesthesia or infiltrative anaesthesia, in both cases…
- Conditions
- Edentulous Jaw, Dental Implant, Anesthesia, Local
- Trial name
- NCT04395690
- Testing
- Dental Implant Placement in the posterior mandible
- Where
- 8 sites in Spain
- Volunteers
- 96 people
- Sponsor
- Aula Dental Avanzada
Pain Perception of the New Device, The Pain Related Behavior
Computer Controlled Local Anesthesia in Children
Introduction: Effective pain control is critical in pediatric dentistry. The effectiveness of pain control in children can be influenced by child characteristics .
- Conditions
- Pain Perception of the New Device, The Pain Related Behavior, The Effectiveness of Anesthesia
- Trial name
- STA machine (NCT02025140)
- Testing
- Computer controlled anesthesia, conventional anesthesia syringe
- Where
- Saudi Arabia
- Volunteers
- 91 people, healthy volunteers welcome
- Sponsor
- King Abdulaziz University
Hip Dysplasia
Can PLIA Reduce Early Post-operative Pain After PAO Surgery?
The goal of this clinical trial is to compare different peri-incisional local infiltrative anesthesia (PLIA) methods in patients ages 13 to 50 undergoing a periacetabular osteotomy (PAO). The main questions to answer here are: 1.
- Trial name
- PILA PAO (NCT06519955)
- Testing
- Ropivacaine, Epinephrine, Ketorolac, NaCl (Saline)
- Where
- United States
- Volunteers
- 121 people, healthy volunteers welcome
- Sponsor
- Michael C Willey
Anesthesia, Local Anesthesia
Can Caudal Dexmedetomidine Provide Effective Analgesia?
The goal of this clinical trial is to evaluate if caudal dexmedetomidine can provide effective analgesia during inguinoscrotal surgeries in pediatrics, if used caudally alone (and not as an adjunct to caudal bupivacaine).
- Trial name
- NCT05902780
- Testing
- Caudal Bupivacaine injection, Caudal Dexmedetomidine Injection
- Volunteers
- 50 people
- Sponsor
- Benha University