Clinical trials: Anesthesia, Local
Ilioinguinal Nerve Block, Local Anesthesia
Comparing Ilioinguinal Single-shot and Three-layer Blocks
Ilio-inguinal nerve blocks have a long history of efficacy in treatment of post-operative pain following inguinal surgery. Several anatomic studies have shown that the nerves supplying the inguinal area have a certain degree of…
- Conditions
- Ilioinguinal Nerve Block, Local Anesthesia, Post-operative Analgesia
- Trial name
- NCT01625780
- Testing
- 3-layer block, Single-shot block
- Where
- Canada
- Volunteers
- 32 people
- Sponsor
- University of Alberta
Local Anesthesia
Effect of a Candy Flavoring Before Local Anesthesia on Anxiety and Pain Perception in Children
This is a randomized clinical trial that aimed to test the effect of using sugar-free flavors as a sensory distraction technique during local anesthesia on pain perception when compared to a negative control group.
- Trial name
- NCT05727527
- Testing
- Local Anesthesia 1, Local Anesthesia 2
- Where
- Jordan
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- King Abdullah University Hospital
Behavior, Child, Dental Anxiety
Dental Attire Effect on Children's Dental Anxiety
The aim of this study is to evaluate the effect of friendly attire on dental anxiety among children visiting dental office in comparison with conventional attire.
- Conditions
- Behavior, Child, Dental Anxiety, Anesthesia, Local
- Trial name
- NCT06122883
- Testing
- Evaluation the effectiveness of distraction in the reception area in the management of anxious pediatric patients during dental local anesthesia, Evaluation the effectiveness of distraction in the treatment area in the management of anxious pediatric patients during dental local anesthesia, Evaluation the effectiveness of distraction in both reception and treatment areas in the management of anxious pediatric patients during dental local anesthesia
- Where
- Syria
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Damascus University
Anesthesia, Local
Comparison of US-guided Single-dose Thoracic Paravertebral, Erector Spinae Plane and Serratus Anterior Plane Blocks
This study evaluates the analgesic effects of ultrasound-guided regional techniques, Thoracic Paravertebral Block (TPVB), Erector Spinae Plane Block (ESPB) and Serratus Anterior Plane Block(SAPB) by comparing postoperative total…
- Trial name
- NCT05431062
- Testing
- Bupivacain
- Volunteers
- 60 people
- Sponsor
- Istanbul University
Limb Fracture
Impact of Continuous Regional Analgesia in Severe Trauma Patients
Regional analgesia, based on its physiological effects and efficacy, is used for optimal perioperative pain relief. However, for acute pain in multiple trauma patients in a critical condition, it has not been prospectively…
- Trial name
- ALRréa (NCT04546503)
- Testing
- Continuous Regional analgesia, Control Group
- Where
- France
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University Hospital, Montpellier
Dental Anxiety
Comparison of Virtual Reality and Mixed Reality Head-Mounted Displays for Dental Anxiety Control During Local Anesthesia in Children
Dental anxiety is a common problem in children and may negatively affect cooperation, pain perception, and treatment success during dental procedures.
- Trial name
- NCT07398105
- Testing
- Audiovisual Distraction Using Head-Mounted Display
- Where
- Turkey (Türkiye)
- Volunteers
- 142 people, healthy volunteers welcome
- Sponsor
- Selcuk University
Anesthesia, Pediatric Surgery
Intravenous Dexmedetomidine as an Adjuvant to Locoregional Anesthesia in Pediatric Surgery
The main objective of this study is to study the impact of intravenous dexmedetomidine combined with locoregional anesthesia on postoperative pain in children undergoing surgery.
- Trial name
- DEXPED (NCT06736483)
- Testing
- Dexmedetomidine, Face Legs Activity Cry Consolability scale, Post-Hospitalization Behavior Questionnaire
- Where
- France
- Volunteers
- 200 people
- Sponsor
- University Hospital, Montpellier
Laparoscopic Appendectomy
Comparing Pain Relief Between Two Methods of Freezing Injections in Children Having Their Appendix Removed
Laparoscopic appendectomies are the most common emergency surgeries performed in children. Despite being considered minimally invasive surgeries, they can result in substantial postoperative pain and 2 of 3 patients require…
- Trial name
- NCT06945263
- Testing
- Rectus Sheath Block, Local Anesthetic at the Umbilical Port Site, Intravenous Dexamethasone
- Where
- Canada
- Volunteers
- 32 people
- Sponsor
- University of British Columbia
Pain Management
Pain Reduction Using Vibration and Topical Anesthesia
The goal of this clinical trial is to study if a powered toothbrush providing vibrations compared with 20% benzocaine topical gel is more effective in reducing pain before local anesthetic injections in children aged 6-12 years…
- Trial name
- TG-EB-Eff (NCT06804616)
- Testing
- 20% benzocaine Gel, Powered Toothbrush
- Where
- Pakistan
- Volunteers
- 60 people
- Sponsor
- University of Lahore
Anesthesia
Comparison of Articaine Mandibular Infiltration to Lidocaine Inferior Alveolar Nerve Block in Pediatric Patients
This is a prospective, single-blind, parallel-design randomized controlled clinical trial that aims compare the effectiveness of articaine local infiltration to lidocaine inferior alveolar nerve block (IANB) for restorative…
- Trial name
- NCT04865848
- Testing
- Dental local anesthesia
- Where
- United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- University of Illinois Chicago
Laparoscopic Colon Resection, Perioperative Analgesia
Intravenous and Intraperitoneal Lignocaine for Perioperative Analgesia in Laparoscopic Colon Resections
The aim of this study is to investigate the analgesic effects of intraperitoneal lignocaine (IPL) compared with intravenous lignocaine (IVL) after laparoscopic colon resections.
- Trial name
- NCT03105193
- Testing
- IV Saline bolus and infusion, IP Saline bolus and infusion, IV lignocaine bolus and infusion
- Where
- New Zealand
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Auckland, New Zealand
Regional Anesthesia Morbidity
Assessing Current Peripheral Nerve Block Catheter Fixation and Dressing Strategies: An Equivalence Study
The investigators' objective is to evaluate whether any of the various peripheral nerve block catheter dressing strategies currently employed by the Boston Children's Hospital Regional Anesthesia Service has any differential…
- Trial name
- NCT02926521
- Testing
- 2-octyl cyanoacrylate, Gum Mastic
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Boston Children's Hospital
Scoliosis Idiopathic Adolescent
The Effect of Dexamethasone Administration Route and Local Anesthetic Concentration on Pain, Inflammatory Response, and Neuromonitoring in Children Undergoing Scoliosis Correction
Scoliosis correction surgery in children is a complex procedure with significant risks, including postoperative pain, inflammatory response, and potential neurological complications.
- Trial name
- NCT06789029
- Testing
- perineural Dexamethasone, intravenous Dexamethasone
- Where
- Poland
- Volunteers
- 60 people
- Sponsor
- Poznan University of Medical Sciences
Healthy Participants, Tooth Extraction
Application Of Dentapen In Dental Local Infiltration Anesthesia
The goal of this clinical study is to compare patients' self-reported pain and mental stress during infiltration anesthesia between conventional syringe and Dentapen.
- Conditions
- Healthy Participants, Tooth Extraction, Orthodontic Patients
- Trial name
- NCT07431801
- Testing
- computer controlled local anesthesia delivery device (Dentapen), Control
- Where
- Vietnam
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Son Hoang Le
Dental Anxiety, Pain
Dental Anxiety and Pain During Inferior Alveolar Nerve Block in Children: the Effects of Two Distraction Techniques
Objectives: To compare the effectiveness of virtual reality (VR) and external cooling and vibration distraction techniques on dental anxiety and pain in children during inferior alveolar nerve block (IANB).
- Conditions
- Dental Anxiety, Pain, Distraction Methods, Local Anesthesia
- Trial name
- NCT06788301
- Testing
- Inferior Alveolar Nerve Block, VR eyeglasses, Buzzy device
- Where
- Turkey (Türkiye)
- Volunteers
- 158 people, healthy volunteers welcome
- Sponsor
- Pamukkale University
Hemorrhoids
Local Anaesthetic Day-care Haemorrhoidectomy Challenges Traditional Concepts - a Randomised Controlled Trial
Background: Local anaesthetic day-care open haemorrhoidectomy (LH) is feasible, cheap and may be the cost-effective surgical approach to third degree haemorrhoids.
- Trial name
- NCT00503269
- Testing
- Hemorrhoidectomy
- Where
- United Kingdom
- Volunteers
- 42 people
- Sponsor
- East Kent Hospitals University NHS Foundation Trust
Analgesic Adverse Reaction
Psoas Compartment Block (PCB) Versus L.A Infiltration and Remifentanil Infusion During EVAR
Endovascular aneurysm repair (EVAR) was introduced in 1990 for the first time as a minimally invasive procedure instead of the conventional open surgical repair, with the aim to decrease morbidity and mortality .
- Trial name
- NCT03443518
- Testing
- Psoas Compartment Block (PCB), Local Anesthesia infiltration, Normal saline 0.9% IV infusion
- Where
- 2 sites in Saudi Arabia
- Volunteers
- 30 people
- Sponsor
- Dr. Erfan and Bagedo General Hospital
Catheterization, Peripheral
The Main Content of This Study is to Use Virtual Reality Technology Combined With Local Anesthesia With Lidocaine Injection at Different Times to Reduce the Pain of PICC in School-age Children
We try to through the use of virtual reality technology in combination with lidocaine in different injection time to reduce the pain of PICC catheter school-age children.
- Trial name
- NCT06562829
- Testing
- Virtual reality technology, different timing of lidocaine injection
- Where
- China
- Volunteers
- 174 people
- Sponsor
- Qi Yu
Knee Injury
Needleless Jet Injected (J-Tip) Lidocaine in Children Undergoing Regional Anesthesia Prior to Knee Arthroscopy
Purpose of this study is to investigate the pain outcomes and satisfaction of pain relief for pediatric patients receiving needleless jet-injected (J-Tip) lidocaine prior to regional anesthesia with femoral and/or sciatic nerve…
- Trial name
- NCT02649322
- Testing
- J-Tip, Syringe and 25 gauge needle
- Where
- United States
- Volunteers
- 115 people
- Sponsor
- Orlando Health, Inc.
Pain, Anxiety
Local Anesthesia Pen vs Conventional Syringe In The Treatment of Pain and Dental Anxiety
The goal of this is to compare pain and anxiety that may occur during dental anesthesia delivery using conventional dental syringe and the dental anesthesia injector (wireless pain less pen in pediatric dentistry.
- Trial name
- NCT07656194
- Testing
- Dental anesthesia injector
- Where
- Saudi Arabia
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Shahad Abudawood