Clinical trials: Anesthesia, Obstetrical
Pregnancy Complications, Cesarean Section Complications
A Quality Improvement Project - Peripartum Operating Room Leveling System
Investigators propose a four-category triaging system to delineate and facilitate the communication and action plan for all types of obstetric OR cases via a multidisciplinary approach.
- Conditions
- Pregnancy Complications, Cesarean Section Complications, Morbidity;Perinatal
- Trial name
- NCT03552419
- Volunteers
- 1,380 people
- Sponsor
- Johns Hopkins University
Cesarean Section
Ultrasound Guided Spinal Anesthesia in Non Obese Obstetric Patients
The classical method for spinal anesthesia relies on the use of bony landmarks to identify the level and point of entry of the spinal needle.
- Trial name
- NCT01440400
- Testing
- Ultrasound guided spinal anesthesia
- Where
- United Arab Emirates
- Volunteers
- 150 people
- Sponsor
- Corniche Hospital
Labor Pain
Labor Analgesia With Ropivacaine and Clonidine
The aim of the present study was to examine, for pain relief during labor, the efficacy of two pharmacological approaches - the 0.125% ropivacaine alone and the 0.0625% ropivacaine added to 75 ug clonidine, both by epidural…
- Trial name
- LA (NCT00626977)
- Testing
- ropivacaine, ropivacaine and clonidine
- Where
- Brazil
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- UPECLIN HC FM Botucatu Unesp
Obstetric, Cesarean Birth
Hyperangulated vs. Macintosh Style Blades for Intubation in Obstetric Patients
Cesarean section under general anesthesia requires intubation (insertion of a tube through the mouth into the breathing pipe to support breathing during the surgery).
- Conditions
- Obstetric, Cesarean Birth, Airway Anesthesia, Intubation
- Trial name
- ANGLED (NCT07667010)
- Testing
- Macintosh Style Blade, Hyperangulated blade
- Where
- Canada
- Volunteers
- 100 people
- Sponsor
- Samuel Lunenfeld Research Institute, Mount Sinai Hospital
Twin Pregnancy, Neonate
Neonatal Outcomes in Twin Pregnancies
Multiple pregnancies are associated with increased maternal and fetal risks compared to singleton pregnancies. Additionally, the cesarean section rate is quite high in multiple pregnancies.
- Trial name
- NCT05104255
- Testing
- Spinal anesthesia, General anesthesia
- Volunteers
- 527 people, healthy volunteers welcome
- Sponsor
- Derince Training and Research Hospital
Cesarean Section, Anesthesia, Obstetric
Evaluation of the Typical Spinal Block During Cesarean Delivery
This will be a prospective, observational, single-center study to evaluate the accuracy of sensory testing by blunt 16-gauge plastic cannula during the 15 minutes after spinal injection for predicting spinal failure.
- Trial name
- NCT06206044
- Testing
- Intrathecal 1.6 ml 0.75% bupivacaine in 8.25% dextrose combined with 15 mcg fentanyl and 150 mcg preservative-free morphine
- Where
- United States
- Volunteers
- 250 people
- Sponsor
- Oregon Health and Science University
Medical Education, Resident Education
Impact of Mental Training on the Stress of Anaesthesiology Residents Before Performing Obstetrical Epidural Analgesia
Anaesthetists are trained from the beginning of their residency to perform high-risk procedures, often in high-stress environments, that can adversely affect both their technical and non-technical performance.
- Conditions
- Medical Education, Resident Education, Anesthesia, Epidural Analgesia, Obstetric
- Trial name
- NCT07183618
- Testing
- Mental training group
- Where
- France
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- University Hospital, Rouen
Neurodevelopmental Disorders, Behavior
Effect of Obstetric Anesthesia and Delivery Mode On Neurodevelopmental And Behavioural Outcomes In A Population-Based Birth Cohort
The study aims to determine: 1. The association between Obstetric anesthesia events at delivery (such as mode of anesthesia, drugs given, desaturation and hypotension) on pediatric neurodevelopmental and behavioural outcomes. 2.
- Trial name
- NCT05196750
- Testing
- Behavioural questionnaires and assessments on mother and child
- Where
- 2 sites in Singapore
- Volunteers
- 1,176 people
- Sponsor
- National University Hospital, Singapore
Obstetrical Complication of Anesthesia
Effects of Intraoperative Oxygen Therapy on Oxygenation of Newborns Born Via Elective Cesarian Section
In this study the investigators examine the effects of intraoperative oxygen administration to the mother on certain enzyme functions of the newborn.
- Trial name
- NCT02804555
- Testing
- Oxygen
- Where
- Hungary
- Volunteers
- 107 people
- Sponsor
- Szeged University
High Risk Pregnancy, Multidisciplinary Communication
The Center for Peripartum Optimization
In January 2017 investigators started a Center for Peripartum Optimization (CPO) with the aim of optimizing a patient's clinical status in an outpatient setting to minimize unnecessary laboratory tests and studies, costly…
- Conditions
- High Risk Pregnancy, Multidisciplinary Communication, Communication, Obstetric Complication
- Trial name
- NCT03522909
- Testing
- Seen in clinic
- Where
- United States
- Volunteers
- 250 people
- Sponsor
- Johns Hopkins University
Postpartum Hemorrhage, Uterine Atony
ED90 Determination of Carbetocin for the Prevention of Uterine Atony in Women Undergoing an Elective Cesarean Delivery
The purpose of this trial is to determine the effective dose of carbetocin which would prevent the occurrence of postpartum uterine atony in 90% of women undergoing an elective cesarean delivery.
- Trial name
- NCT01579201
- Testing
- Carbetocin
- Where
- Canada
- Volunteers
- 40 people
- Sponsor
- Maisonneuve-Rosemont Hospital
Cesarean Delivery, General Anesthesia
The Society for Obstetric Anesthesia and Perinatology Research Network General Anesthesia Registry
The SOAP registry is a prospective, multicenter, electronic registry. The goal is to investigate the indications, mode of airway management, predisposing factors, and obstetric and anesthetic outcomes of pregnant patients who…
- Trial name
- NCT06030063
- Where
- 35 sites in United States, Canada
- Volunteers
- 5,000 people, healthy volunteers welcome
- Sponsor
- Yale University
Obstetric Anesthesia, Spinal Anesthesia
ED50 Determination of Hydroxyethylstarch for Treatment of Hypotension During Cesarean Section Under Spinal Anesthesia
The purpose of this trial is to determine the effective volume of hydroxyethylstarch 130/0.4 which would prevent the occurence of maternal hypotension in 50% of healthy pregnant women undergoing a cesarean section under spinal…
- Conditions
- Obstetric Anesthesia, Spinal Anesthesia, Hypotension, Fluid Therapy
- Trial name
- NCT01415284
- Testing
- Hydroxyethylstarch 130/0.4
- Where
- Canada
- Volunteers
- 30 people
- Sponsor
- Maisonneuve-Rosemont Hospital
Obstetric Anesthesia Care
Obstetric Anesthesia and Analgesia Month Attributes in Czech Republic
A national survey of current practices, preferred drug and technique choices for obstetric anesthesia and analgesia in Czech Republic.
- Trial name
- OBAAMA (NCT01830218)
- Testing
- Obstetric anesthesia and analgesia
- Where
- Czechia
- Volunteers
- 1,940 people
- Sponsor
- Charles University, Czech Republic
Preeclampsia
Peripartum Anesthetic Management of Patients With Preeclampsia
The investigators will conduct a prospective, observational multicentral international study of perioperative management of patients with preeclampsia.
- Trial name
- NCT05237011
- Where
- Israel
- Volunteers
- 1,500 people
- Sponsor
- Shaare Zedek Medical Center
Obstetric Anesthesia Care
Obstetric Anaesthesia And Analgesia Month Attributes - in COVID-19
A national survey of current practices, preferred drug and technique choices for obstetric anesthesia and analgesia and to evaluate the impact of COVID-19 pandemic on obstetric anesthesia and analgesia in Czech Republic and…
- Trial name
- OBAAMA-COV (NCT04912791)
- Testing
- Obstetric anesthesia and analgesia
- Where
- Czechia
- Volunteers
- 5,000 people
- Sponsor
- Brno University Hospital
Obstetric Anesthesia Care
Obstetric Anaesthesia And Analgesia Month Attributes - International
A national survey of current practices, preferred drug and technique choices for obstetric anesthesia and analgesia in Czech Republic and Slovak Republic.
- Trial name
- OBAAMA-INT (NCT02380586)
- Testing
- Obstetric anesthesia and analgesia
- Where
- Czechia
- Volunteers
- 3,040 people
- Sponsor
- Brno University Hospital
Hypothermia, Anesthesia
Electric Warming Mattress to Prevent IPH During LSCS
This study will demonstrate whether an electric warming mattress can reduce the number of patients who get cold and shiver after elective cesarean section.
- Conditions
- Hypothermia, Anesthesia, Obstetric Anesthesia Problems
- Trial name
- ObsIPH (NCT01054209)
- Testing
- Warming with warming mattress
- Where
- United Kingdom
- Volunteers
- 116 people
- Sponsor
- Brighton and Sussex University Hospitals NHS Trust
Anesthesia
Impact of Ultrasound in Obstetric Anesthesia Central Blocks
This study aimed to evaluate the use of ultrasound in obstetric anesthesia, specifically for measuring epidural and intrathecal distances in pregnant women undergoing cesarean section.
- Trial name
- NCT06761222
- Testing
- The use of ultrasound in central blocks
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Ege University
Obstetric Anesthesia Problems, High-Risk Pregnancy
Effect of Intra-abdominal Pressure to the Level of the Sensory Block at Caesarean Section Under Spinal Anesthesia
It is known that an increase in intra-abdominal pressure (IAP) causes a decrease in the volume of cerebrospinal fluid in the lumbar and lower thoracic region, which may contribute to the development of more high spinal block.
- Trial name
- IAPSB (NCT02237092)
- Testing
- Measurement of IAP
- Where
- Russia
- Volunteers
- 196 people, healthy volunteers welcome
- Sponsor
- Tver Regional Perinatal Center