Clinical trials: Anesthesia,General
Trigeminocardiac Reflex, Hemodynamic Changes
Association Between Lingual Retraction and Hemodynamic Changes in Patients Receiving Dental Treatment Under General Anesthesia
This study aims to investigate the association between sudden decreases in heart rate and blood pressure during dental procedures requiring lingual retraction-such as fillings, root canal treatments, tooth extractions, and cyst…
- Conditions
- Trigeminocardiac Reflex, Hemodynamic Changes, Dental Procedures
- Trial name
- NCT07240688
- Where
- Turkey (Türkiye)
- Volunteers
- 85 people
- Sponsor
- Kırıkkale University
Pain, Anesthesia
Pupillary Pain Index and Reaction to Skin Incision
During routine general anesthesia (not standardized, left to the discretion of the attending anesthesiologist), pupillary pain index was measured one minute before skin incision.
- Conditions
- Pain, Anesthesia, Surgery
- Trial name
- NCT03103360
- Testing
- videopupillometer, skin incision
- Where
- France
- Volunteers
- 53 people
- Sponsor
- Pr Isabelle CONSTANT
General Anesthesia
Gastric Ultrasound in Paediatric Anaesthesia
Anesthesia for emergency surgery is a situation at risk of pulmonary aspiration of gastric contents. It has been previously reported that bedside two-dimensional ultrasonography can be a useful tool for anesthesiologists to…
- Trial name
- ECHOGASTRO (NCT02584348)
- Testing
- Gastric ultrasound
- Where
- France
- Volunteers
- 146 people
- Sponsor
- Hospices Civils de Lyon
Anesthesia
NoL Index Response to Stimulation in Anesthetized Children
The Nociception Level (NoL) is an index obtained via a non-invasive monitor, that is currently used to assess nociception in anesthetized adults. The NoL index varies from 0 to 100.
- Trial name
- STIMNOL (NCT05233449)
- Testing
- NoL monitor, Stimulation
- Where
- 2 sites in France
- Volunteers
- 30 people
- Sponsor
- University Hospital, Lille
Alzheimer´s Disease, General Anesthesia
Is There a Relationship Between Previous Exposure to General Anesthesia and the Development of Alzheimer´s Disease?
The purpose of this study is to compare exposure to general anesthesia between cases with a diagnosis of Alzheimer´s disease and controls without diagnosis, through studies of medical records.
- Trial name
- DEMA (NCT01695889)
- Where
- Sweden
- Volunteers
- 877 people
- Sponsor
- University Hospital, Linkoeping
Neurodevelopmental Delay
General Anesthesia/Surgical Exposure on White Matter Development in Children
International large-scale clinical studies have found that prolonged or repeated exposure to general anesthesia drugs in infancy and early childhood can lead to an increased risk of long-term neurodevelopmental abnormalities in…
- Trial name
- NCT06367062
- Testing
- MRI
- Volunteers
- 210 people
- Sponsor
- Shanghai Ninth People's Hospital Affiliated to Shanghai Jiao Tong University
Intraoperative Ventilation
A Comparison of Different Ventilation Strategies in Children Using the Proseal™ Laryngeal Mask Airway
The purpose of this research study is to compare difference between breathing by oneself or with the partial help from an anesthesia machine in children under general anesthesia.
- Trial name
- NCT00966433
- Testing
- Spontaneous ventilation, Pressure support Ventilation, Pressure control ventilation
- Where
- United States
- Volunteers
- 33 people
- Sponsor
- Wake Forest University Health Sciences
Spinal Anesthesia, General Anesthesia
Spinal and General Anesthesia in Neonates Undergoing Herniorrhaphy
The aim of this study is to compare spinal and general anesthesia in neonates undergoing herniorrhaphy.
- Conditions
- Spinal Anesthesia, General Anesthesia, Neonates, Inguinal Herniorrhaphy
- Trial name
- NCT06352606
- Testing
- Spinal anesthesia, General anesthesia
- Where
- Egypt
- Volunteers
- 74 people
- Sponsor
- Tanta University
Anesthesia
Comparing EEG Patterns in Different Age Groups During General Anesthesia With Sevoflurane
This study is being conducted to evaluate and assess the electroencephalography wave patterns in different age patients undergoing surgery under general anesthesia.
- Trial name
- NCT03559504
- Testing
- Sevoflurane Inhal Soln
- Where
- China
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Second Affiliated Hospital of Wenzhou Medical University
Surgeries Undergoing General Anesthesia
Study: Study to Compare Video Miller Device to Direct Laryngoscopy
The purpose of this study is to compare: the standard pediatric intubation instrument (Miller blade) used as direct laryngoscopy during tracheal intubation to the VideoMiller device (the standard pediatric blade with a camera…
- Trial name
- NCT01371032
- Testing
- VideoMiller, Direct Laryngoscopy
- Where
- United States
- Volunteers
- 28 people
- Sponsor
- Cedars-Sinai Medical Center
Postoperative Nausea and Vomiting
Aprepitant PO vs Ondansetron IV for Prevention of Postoperative Nausea and Vomiting
Postoperative nausea and vomiting (PONV) persists as one of the more common complications of surgery. Although rarely life-threatening, it is the postoperative outcome that is most unfavorable to patients, even more undesirable…
- Trial name
- NCT00699894
- Testing
- aprepitant 40 mg, ondansetron 4 mg
- Where
- United States
- Sponsor
- Northwell Health
Postoperative Pain
Postoperative Discomfort After Dental General Anesthesia
The aim of this prospective, randomised, controlled clinical trial was to compare immediate postoperative discomfort, emergence delirium and recovery time of the patients intubated using either laryngeal mask airway or…
- Trial name
- NCT03197753
- Testing
- Laryngeal mask airway, Nasotracheal intubation
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Aydin Adnan Menderes University
Intratracheal, Dexmedetomidine
Effect of Intratracheal Dexmedetomidine Administration on Recovery From General Anesthesia in Pediatrics Undergoing Lower Abdominal Surgery:
The incidence of intratracheal tube-induced laryngeal irritation, including coughing, bucking, and cardiovascular stimulation, on emergence from general anesthesia has been reported to occur in 38% and 96% of cases.
- Trial name
- NCT04385602
- Testing
- Intratracheal dexmedetomidine, Saline Solution
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Assiut University
Surgery
Ankle/Brachial Non-Invasive Blood Pressure Difference During General Anesthesia
Brachial non-invasive blood pressure (NIBP) monitoring is recommended as part of the American Society of Anesthesiology (ASA) basic monitoring package.
- Trial name
- NCT03547401
- Testing
- Ankle Non-invasive Blood pressure measurement, Arm Non-invasive Blood pressure measurement
- Where
- Belgium
- Volunteers
- 25 people
- Sponsor
- Philippe VAN DER LINDEN
Inguinal Hernia
Awake Caudal Catheter vs General Anesthesia
It is well established that preterm inguinal hernias discovered in the NICU pose a significant surgical risk due to the associated co-morbid conditions that accompany these patients.
- Trial name
- NCT05919732
- Testing
- Bupivacaine, Dexmedetomidine, Caffeine, Tylenol, Propofol, rocuronium, caffeine, Tylenol, bupivacaine
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Nemours Children's Clinic
Anesthesia, Sedation
EEG Signal Correlates During Anesthesia and Sedation in Adults and Children
This prospective, multicenter, non-interventional observational study investigates the correlates between electroencephalographic (EEG) signals and pharmacological/clinical parameters during general anesthesia and procedural…
- Conditions
- Anesthesia, Sedation, Consciousness Monitors
- Trial name
- SPECTRALADUPED (NCT07460414)
- Where
- 2 sites in France
- Volunteers
- 330 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
General Anesthesia
Determination of Optimal Positive End-expiratory Pressure Using Electrical Impedance Tomography in Children Under General Anesthesia: Comparison Between Supine and Prone Positions
The purpose of this study was to determine the appropriate positive end-expiratory pressure (PEEP) using electrical impedance tomography (EIT) in children under general anesthesia and to investigate whether there is a difference…
- Trial name
- NCT05275309
- Testing
- Exploration of optimal PEEP in supine and prone position
- Where
- South Korea
- Volunteers
- 33 people
- Sponsor
- Seoul National University Hospital
Pediatric Anesthesia, Airway Management
Effective Dose of Alfentanil Combined With Propofol for Laryngeal Mask Airway Insertion in Children
This study uses a prospective, up-and-down sequential allocation method to determine the median effective dose (ED50) and 95% effective dose (ED95) of alfentanil combined with propofol for successful laryngeal mask airway (LMA)…
- Conditions
- Pediatric Anesthesia, Airway Management, General Anesthesia, LMA
- Trial name
- NCT07581665
- Testing
- Alfentanil
- Where
- China
- Volunteers
- 23 people
- Sponsor
- Zhongshan Ophthalmic Center, Sun Yat-sen University
Pediatric Dentistry
Change in Quality of Life After Full Mouth Rehabilitation Under General Anesthesia in a Group of Egyptian Children With Down Syndrome
To assess oral health related quality of life (OHRQOL) after full mouth rehabilitation under GA in a group of Egyptian children with down syndrome .
- Trial name
- NCT05146271
- Testing
- Complete mouth rehabilitation under general anesthesia in a group of Egyptian children with Down syndrome
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Cairo University
Hemodynamic Instability
Role of Nebulized Dexmedetomidine in Blunting the Effects of Direct Laryngoscopy and Endotracheal Tube on Heart Rate and Blood Pressure.
The goal of this interventional study is to check the effectiveness of nebulized Dexmedetomidine in preventing the rise in blood pressure and heart rate in patients undergoing General Anesthesia.
- Trial name
- NCT06103721
- Testing
- Dexmedetomidine Injection [Precedex], Normal Saline
- Where
- Pakistan
- Volunteers
- 126 people, healthy volunteers welcome
- Sponsor
- Muhammad Haroon Anwar