Clinical trials: Anesthesia,General
Oxygen Toxicity, Oxidative Stress
Optimized Oxygen Delivery During General Anesthesia in Newborn Infants
An open randomized control trial investigating the delivery of two levels of inspired oxygen to newborn infants during general anesthesia.
- Trial name
- ANOXneo (NCT02698020)
- Testing
- Room-air
- Where
- Sweden
- Volunteers
- 35 people
- Sponsor
- Uppsala University
General Anesthesia, Dexmedetomidine
General Anesthesia Versus Sedation By Dexmedetomidine and Ketamine With Local Infiltration for Percutaneous Transcatheter Closure of Atrial Septal Defect in Pediatric Patients
The aim of the present study is to compare between general anesthesia versus sedation with dexmedetomidine and ketamine with local infilteration at the catheter insertion site in pediatric patients undergoing transcutaneous…
- Conditions
- General Anesthesia, Dexmedetomidine, Ketamine, Local Infiltration
- Trial name
- NCT06431178
- Testing
- General Anesthesia, Local anesthesia
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Tanta University
Perfusion Index, Plethysmography
Evaluation of Caudal Block and Ilioinguinal-ilioohypogastric Nerve Block Efficacy with Perfusion Index (PI)
The study is a prospective, randomised, controlled double-blind clinical trial. The primary aim was to evaluate the efficacy of caudal block and ilioinguinal-iliohypogastric nerve block with PI and PVI in pediatric inguinal…
- Conditions
- Perfusion Index, Plethysmography, Anesthesia, Caudal, Nerve Block
- Trial name
- NCT06203743
- Testing
- caudal block group, ilioinguinal-iliohypogastric nerve block group
- Where
- Turkey (Türkiye)
- Volunteers
- 102 people
- Sponsor
- Bursa Yuksek Ihtisas Training and Research Hospital
Pain, Postoperative
Preemptive Analgesia for Postoperative Pain Control for Dental Treatment Under General Anesthesia
The aim of this study was to compare the analgesic-treated children with analgesic prior to the treatment and to compare the postoperative analgesic needs of children undergoing dental treatment under general anesthesia.
- Trial name
- NCT03852602
- Testing
- Preemptive Analgesics, Control
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people
- Sponsor
- Aydin Adnan Menderes University
Surgery
Effect of Dexmedetomidine on QT Interval in Pediatric Patients Under General Anesthesia
Various medications used in anesthesia have been implicated in the prolongation of QT interval. Recently, there has been an increase in the use of dexmedetomidine in patients presenting for surgeries given its beneficial…
- Trial name
- NCT01917786
- Testing
- ECG
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Senthil G. Krishna
Preoperative Anxiety, Dental Anxiety
Digital Storytelling-Based Animation for Preoperative Anxiety in Children
This randomized controlled trial evaluates the effect of a digital storytelling-based animation on preoperative anxiety and physiological parameters in children aged 5-12 years undergoing dental treatment under general…
- Trial name
- NCT07825493
- Testing
- Digital Storytelling-Based Animation
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people
- Sponsor
- Recep Tayyip Erdogan University
Surgeries Undergoing General Anesthesia
Study: Study to Compare Video Miller Device to Direct Laryngoscopy
The purpose of this study is to compare: the standard pediatric intubation instrument (Miller blade) used as direct laryngoscopy during tracheal intubation to the VideoMiller device (the standard pediatric blade with a camera…
- Trial name
- NCT01371032
- Testing
- VideoMiller, Direct Laryngoscopy
- Where
- United States
- Volunteers
- 28 people
- Sponsor
- Cedars-Sinai Medical Center
Awareness, Anesthesia
Validity of Perfusion Index to Evaluate the Level of General Anaesthesia in Children.
The aim of this study is to evaluate the validity of perfusion index to determine the level of anesthesia in comparison with auditory evoked potential in children undergoing tonsillectomy.
- Trial name
- PI/AAI (NCT03412214)
- Testing
- Perfusion index detected by pulse oximeter, AAI
- Where
- Egypt
- Volunteers
- 41 people
- Sponsor
- Assiut University
Anesthesia
Right Lateral Positioning and Its Effect on Induction of General Anesthesia for Children
The quality of induction with sevoflurane, along with its ability to generate optimal conditions for Laryngeal Mask Airway (LMA) insertion without supplemental opioids or muscle relaxants, has also been well documented.
- Trial name
- NCT02654184
- Testing
- supine position, Right lateral position
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Assiut University
Fasting
Blood Glucose Levels in Children During Anesthesia
This cross-sectional study aims to investigate blood glucose levels in children during general anesthesia and explore the incidence of hypoglycemia after anesthesia induction in relation to preoperative fasting.
- Trial name
- NCT06915493
- Testing
- General Anesthesia
- Where
- Iceland
- Volunteers
- 350 people
- Sponsor
- Landspitali University Hospital
Adverse Effect of Other General Anesthetics, Sequela
Automated Assessment of Difficult Airway With Facial Recognition Techniques
General anaesthesia mandates artificial ventilation and tracheal intubation in order to provide patients with artificial breathing.
- Trial name
- PeScho (NCT02022397)
- Where
- Switzerland
- Volunteers
- 6,000 people, healthy volunteers welcome
- Sponsor
- University of Lausanne Hospitals
Surgery, Anesthesia
Nalbuphine and Flurbiprofen for Oculoplastic Surgery
The purpose of this study is to evaluate the postoperative pain and discomfort using flurbiprofen axetil or nalbuphine administration after oculoplastic surgery under general anesthesia.
- Conditions
- Surgery, Anesthesia, Pain
- Trial name
- NCT03422887
- Testing
- Nalbuphine, Flurbiprofen Axetil, Nalbuphine and Flurbiprofen Axetil
- Where
- China
- Volunteers
- 330 people
- Sponsor
- Sun Yat-sen University
Airway Complication of Anaesthesia
Effectiveness and Safety of the Levitan Scope for Laryngoscopy and Tracheal Intubation With a Simulated Difficult Airway
A laryngoscope is a medical instrument that is used to get a view of the voice box and the space in between the vocal cords. A laryngoscope is used to place a breathing tube into the trachea (windpipe or airway) to protect the…
- Trial name
- NCT01491984
- Testing
- Laryngoscopy order: 1) MAC, 2) Levitan, Laryngoscopy order: 1) Levitan, 2) MAC
- Volunteers
- 105 people
- Sponsor
- IWK Health Centre
Sore Throat, Intubation;Difficult
Assessment of Post-operative Sore Throat After Scheduled General Anesthesia
Precise description of the technique for intubation or laryngeal mask placement during general anesthesia Research on factors that can influence sore throat due to the placement of an endobuccal or endotracheal device during…
- Trial name
- POST (NCT04115865)
- Testing
- Endotracheal sonde or laryngeal mask
- Sponsor
- University Hospital, Lille
Anesthesia
A Study to Evaluate the Safety and Efficacy of Ultiva (Remifentanil Hydrochloride) in Pediatric Participants General Anesthetised
The purpose of this study is to evaluate the efficacy and safety of JNJ-268229 (Ultiva /Remifentanil Hydrochloride) in pediatric participants between 1 and 15 years of age during maintenance of general anesthesia.
- Trial name
- NCT01998165
- Testing
- Remifentanil
- Where
- 9 sites in Japan
- Volunteers
- 80 people
- Sponsor
- Janssen Pharmaceutical K.K.
Emergence Agitation
Effect of Lollipop on Emergence Delirium in Pediatric Patients Undergoing General Anesthesia
This study aims to evaluate the effectiveness of lollipop administration after surgery in reducing emergence agitation in pediatric patients undergoing anesthesia with sevoflurane at RS Ngoerah.
- Trial name
- LOLLIPOP-ED (NCT07571707)
- Testing
- Lollipop
- Where
- Indonesia
- Volunteers
- 66 people
- Sponsor
- Udayana University
General Anesthetics Toxicity, Postoperative Cognitive Dysfunction
Tau/P-Tau and Neurocognitive Outcomes in Children
The proposed studies are aimed to measure Tau and P-Tau levels in pre- and postoperative blood, urine, feces and saliva, as well as to assess pre- and postoperative neurocognitive function in children (3 to 5 years old) who will…
- Conditions
- General Anesthetics Toxicity, Postoperative Cognitive Dysfunction, Child Development
- Trial name
- NCT03511729
- Where
- 2 sites in United States
- Volunteers
- 20 people
- Sponsor
- Massachusetts General Hospital
Myringotomy
Effect of Dexmedetomidine on Emergence Agitation in Children With or Without Tube Insertion Under General Anesthesia
The investigators are inviting your child to participate in this research study because your child is having myringotomy (putting a tiny incision in the eardrum with or without tube insertion) under general anesthesia.
- Trial name
- NCT01535287
- Testing
- Dexmedetomidine
- Where
- United States
- Volunteers
- 140 people
- Sponsor
- Martin Mueller
Patients Requiring Ambulatory Surgery Under General Anesthesia
Propofol for Supreme LMA Insertion With and Without Remifentanil
The aims of this study were to determine the clinically required concentration of propofol for LMA Supreme insertion, and to examine to what extent remifentanil reduces the dose of propofol and improves conditions for it's…
- Trial name
- SC50 (NCT01974648)
- Testing
- propofol, propofol and remifentanil
- Where
- Spain
- Volunteers
- 59 people
- Sponsor
- Hospital General Universitario Gregorio Marañon
Intraoperative Arterial Hypotension, Infant, Newborn
Determination of the Optimal Dose of Ephedrine in Intraoperative Arterial Hypotension of Newborns and Infants up to 6 Months of Age.
The incidence of arterial hypotension under general anesthesia using sevoflurane is particularly high in newborns and infants up to 6 months of age.
- Trial name
- EPHEDRINE (NCT02384876)
- Testing
- Ephedrine 30mg/10mL injectable solution, single administration, dose : 0.6, 0.8, 1.0, 1.2 and 1.4 mg/kG, Ephedrine 30mg/10mL injectable solution, single administration, dose : 0.1 mg/kG.
- Where
- 3 sites in France
- Volunteers
- 120 people
- Sponsor
- Hospices Civils de Lyon